LOCUS       NM_031573               1381 bp    mRNA    linear   ROD 30-MAR-2024
DEFINITION  Rattus norvegicus phosphorylase kinase catalytic subunit gamma 1
            (Phkg1), mRNA.
ACCESSION   NM_031573
VERSION     NM_031573.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1381)
  AUTHORS   Kwitek,A.E., Gullings-Handley,J., Yu,J., Carlos,D.C., Orlebeke,K.,
            Nie,J., Eckert,J., Lemke,A., Andrae,J.W., Bromberg,S., Pasko,D.,
            Chen,D., Scheetz,T.E., Casavant,T.L., Soares,M.B., Sheffield,V.C.,
            Tonellato,P.J. and Jacob,H.J.
  TITLE     High-density rat radiation hybrid maps containing over 24,000
            SSLPs, genes, and ESTs provide a direct link to the rat genome
            sequence
  JOURNAL   Genome Res 14 (4), 750-757 (2004)
   PUBMED   15060019
REFERENCE   2  (bases 1 to 1381)
  AUTHORS   Brushia,R.J. and Walsh,D.A.
  TITLE     Phosphorylase kinase: the complexity of its regulation is reflected
            in the complexity of its structure
  JOURNAL   Front Biosci 4, D618-D641 (1999)
   PUBMED   10487978
  REMARK    Review article
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 1381)
  AUTHORS   Cawley,K.C., Akita,C.G., Angelos,K.L. and Walsh,D.A.
  TITLE     Characterization of the gene for rat phosphorylase kinase catalytic
            subunit
  JOURNAL   J Biol Chem 268 (2), 1194-1200 (1993)
   PUBMED   8419323
REFERENCE   4  (bases 1 to 1381)
  AUTHORS   Cawley,K.C., Ramachandran,C., Gorin,F.A. and Walsh,D.A.
  TITLE     Nucleotide sequence of cDNA encoding the catalytic subunit of
            phosphorylase kinase from rat soleus muscle
  JOURNAL   Nucleic Acids Res 16 (5), 2355-2356 (1988)
   PUBMED   3357797
REFERENCE   5  (bases 1 to 1381)
  AUTHORS   Salsgiver,W.J. and Lawrence,J.C. Jr.
  TITLE     Rat skeletal muscle phosphorylase kinase: turnover and control of
            isozyme levels in culture
  JOURNAL   Am J Physiol 250 (3 Pt 1), C365-C373 (1986)
   PUBMED   3953807
REFERENCE   6  (bases 1 to 1381)
  AUTHORS   Taira,T., Kii,R., Sakai,K., Tabuchi,H., Takimoto,S., Nakamura,S.,
            Takahashi,J., Hashimoto,E., Yamamura,H. and Nishizuka,Y.
  TITLE     Comparison of glycogen phosphorylase kinases of various rat tissues
  JOURNAL   J Biochem 91 (3), 883-888 (1982)
   PUBMED   6281247
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from
            JAXUCZ010000012.1.
            
            On Nov 26, 2020 this sequence version replaced NM_031573.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: X07320.1, SRR26643289.32209.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760386, SAMEA5760393
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-43                JAXUCZ010000012.1  32475077-32475119
            44-159              JAXUCZ010000012.1  32478645-32478760
            160-338             JAXUCZ010000012.1  32479185-32479363
            339-393             JAXUCZ010000012.1  32479758-32479812
            394-459             JAXUCZ010000012.1  32483781-32483846
            460-623             JAXUCZ010000012.1  32485744-32485907
            624-714             JAXUCZ010000012.1  32486847-32486937
            715-868             JAXUCZ010000012.1  32487083-32487236
            869-994             JAXUCZ010000012.1  32488156-32488281
            995-1381            JAXUCZ010000012.1  32488574-32488960
FEATURES             Location/Qualifiers
     source          1..1381
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="12"
                     /map="12q13"
     gene            1..1381
                     /gene="Phkg1"
                     /gene_synonym="Phkg; PHKIN01"
                     /note="phosphorylase kinase catalytic subunit gamma 1"
                     /db_xref="GeneID:29353"
                     /db_xref="RGD:3325"
     exon            1..43
                     /gene="Phkg1"
                     /gene_synonym="Phkg; PHKIN01"
                     /inference="alignment:Splign:2.1.0"
     exon            44..159
                     /gene="Phkg1"
                     /gene_synonym="Phkg; PHKIN01"
                     /inference="alignment:Splign:2.1.0"
     CDS             77..1243
                     /gene="Phkg1"
                     /gene_synonym="Phkg; PHKIN01"
                     /EC_number="2.7.11.1"
                     /EC_number="2.7.11.19"
                     /EC_number="2.7.11.26"
                     /note="gamma phosphorylase kinase; phosphorylase kinase
                     subunit gamma-1; serine/threonine-protein kinase PHKG1;
                     phosphorylase kinase, gamma 1"
                     /codon_start=1
                     /product="phosphorylase b kinase gamma catalytic chain,
                     skeletal muscle/heart isoform"
                     /protein_id="NP_113761.1"
                     /db_xref="GeneID:29353"
                     /db_xref="RGD:3325"
                     /translation="MTRDEALPDSHSAQNFYENYEPKEILGRGVSSVVRRCIHKPTCQ
                     EYAVKIIDITGGGSFSSEEVQELREATLKEVDILQKVSGHPNIIQLKDTYETNTFFFL
                     VFDLMKRGELFDYLTEKVTLTEKETRKIMRALLEVVCTLHKLNIVHRDLKPENILLDD
                     NMNIKLTDFGFSCQLQPGEKLREVCGTPSYLAPEIIQCSMDEGHPGYGKEVDMWSTGV
                     IMYTLLAGSPPFWHRKQMLMLRMIMDGKYQFGSPEWDDYSDTVKDLVSRFLVVQPQDR
                     CSAEEALAHPFFQEYVVEEVRHFSPRGKFKVICLTVLASVRIYYQYRRVKPVTREIVI
                     RDPYALRPLRRLIDAYAFRIYGHWVKKGQQQNRAALFENTPKAVLLSLAEEEDF"
     exon            160..338
                     /gene="Phkg1"
                     /gene_synonym="Phkg; PHKIN01"
                     /inference="alignment:Splign:2.1.0"
     exon            339..393
                     /gene="Phkg1"
                     /gene_synonym="Phkg; PHKIN01"
                     /inference="alignment:Splign:2.1.0"
     exon            394..459
                     /gene="Phkg1"
                     /gene_synonym="Phkg; PHKIN01"
                     /inference="alignment:Splign:2.1.0"
     exon            460..623
                     /gene="Phkg1"
                     /gene_synonym="Phkg; PHKIN01"
                     /inference="alignment:Splign:2.1.0"
     exon            624..714
                     /gene="Phkg1"
                     /gene_synonym="Phkg; PHKIN01"
                     /inference="alignment:Splign:2.1.0"
     exon            715..868
                     /gene="Phkg1"
                     /gene_synonym="Phkg; PHKIN01"
                     /inference="alignment:Splign:2.1.0"
     exon            869..994
                     /gene="Phkg1"
                     /gene_synonym="Phkg; PHKIN01"
                     /inference="alignment:Splign:2.1.0"
     exon            995..1381
                     /gene="Phkg1"
                     /gene_synonym="Phkg; PHKIN01"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gaattcctgt cacttccatt caagagccta caagaaccta actaggtgct tgggatcccc
       61 tgagatccag ctgaccatga cccgggatga ggccctccct gactctcatt ctgcacagaa
      121 tttctatgag aactacgagc ccaaggagat cctgggcagg ggagtcagca gcgtggtcag
      181 gagatgcatt cacaaaccta cgtgccaaga atacgcagta aaaatcatcg acatcaccgg
      241 cggaggaagc tttagctccg aggaggtaca ggagcttcgg gaagccaccc tgaaggaggt
      301 ggacattctg cagaaggtct caggacaccc caacatcata cagctgaagg acacttacga
      361 gaccaacact ttcttcttct tggtatttga tctgatgaag agaggggaac tctttgacta
      421 tctcacagag aaggtcacct tgactgagaa ggaaaccaga aagatcatgc gggccctgct
      481 ggaggtggtc tgcaccttgc acaaactcaa cattgtccat cgggacctga agccggagaa
      541 catccttctg gatgacaaca tgaacatcaa gctcactgac ttcgggtttt cctgccagct
      601 gcagccagga gagaagctcc gagaggtttg tgggactccc agttatctgg cccccgaaat
      661 catccagtgc tccatggacg aaggccatcc tggctatgga aaggaggtgg acatgtggag
      721 cacaggagtc atcatgtata cgctgctggc tggctccccg cccttctggc accggaagca
      781 aatgctaatg ttgaggatga tcatggatgg caaataccag ttcggctcac cagagtggga
      841 tgactactca gataccgtga aagacttggt atctcgcttc ttggtggtgc aaccccagga
      901 ccgctgctcg gcggaagagg ccttggcgca tcctttcttc caggagtacg tggtggaaga
      961 ggtgcggcac ttcagccctc gagggaagtt caaggtcatc tgtctaactg tgctggcctc
     1021 ggtaaggatc tactaccagt accgtcgggt gaagccggta accagggaga tcgtcatccg
     1081 agacccctac gccctacggc cattgcgcag actcatcgac gcctatgctt tccgcatcta
     1141 cggccactgg gtgaagaaag ggcaacagca gaacagagct gccctcttcg agaacacgcc
     1201 caaggcagtg ctcctctcct tggctgagga ggaggacttc tgaggggtgg cggggcacag
     1261 gggagaaagc aaacagggta cgcgccccca gaactgtgag aagaggatgc ctcaaggagg
     1321 aggcttctgc aaaggagctg tgaccctact ctgcactctc aaaggctcgc cactagatgc
     1381 g
//
