LOCUS       NM_001415143            5248 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus PHD finger protein 2 (Phf2), mRNA.
ACCESSION   NM_001415143 XM_039095667
VERSION     NM_001415143.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 5248)
  AUTHORS   Black,J.C., Van Rechem,C. and Whetstine,J.R.
  TITLE     Histone lysine methylation dynamics: establishment, regulation, and
            biological impact
  JOURNAL   Mol Cell 48 (4), 491-507 (2012)
   PUBMED   23200123
  REMARK    Review article
REFERENCE   2  (bases 1 to 5248)
  AUTHORS   Baba,A., Ohtake,F., Okuno,Y., Yokota,K., Okada,M., Imai,Y., Ni,M.,
            Meyer,C.A., Igarashi,K., Kanno,J., Brown,M. and Kato,S.
  TITLE     PKA-dependent regulation of the histone lysine demethylase complex
            PHF2-ARID5B
  JOURNAL   Nat Cell Biol 13 (6), 668-675 (2011)
   PUBMED   21532585
REFERENCE   3  (bases 1 to 5248)
  AUTHORS   Horton,J.R., Upadhyay,A.K., Hashimoto,H., Zhang,X. and Cheng,X.
  TITLE     Structural basis for human PHF2 Jumonji domain interaction with
            metal ions
  JOURNAL   J Mol Biol 406 (1), 1-8 (2011)
   PUBMED   21167174
REFERENCE   4  (bases 1 to 5248)
  AUTHORS   Ohta,S., Bukowski-Wills,J.C., Sanchez-Pulido,L., Alves Fde,L.,
            Wood,L., Chen,Z.A., Platani,M., Fischer,L., Hudson,D.F.,
            Ponting,C.P., Fukagawa,T., Earnshaw,W.C. and Rappsilber,J.
  TITLE     The protein composition of mitotic chromosomes determined using
            multiclassifier combinatorial proteomics
  JOURNAL   Cell 142 (5), 810-821 (2010)
   PUBMED   20813266
REFERENCE   5  (bases 1 to 5248)
  AUTHORS   Wen,H., Li,J., Song,T., Lu,M., Kan,P.Y., Lee,M.G., Sha,B. and
            Shi,X.
  TITLE     Recognition of histone H3K4 trimethylation by the plant homeodomain
            of PHF2 modulates histone demethylation
  JOURNAL   J Biol Chem 285 (13), 9322-9326 (2010)
   PUBMED   20129925
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000017.1.
            
            On Dec 22, 2022 this sequence version replaced XM_039095667.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643295.53943.1,
                                           SRR26643297.48219.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-212               JAXUCZ010000017.1  15989594-15989805
            213-298             JAXUCZ010000017.1  16025134-16025219
            299-413             JAXUCZ010000017.1  16028577-16028691
            414-574             JAXUCZ010000017.1  16032056-16032216
            575-716             JAXUCZ010000017.1  16034773-16034914
            717-903             JAXUCZ010000017.1  16037261-16037447
            904-1066            JAXUCZ010000017.1  16038719-16038881
            1067-1154           JAXUCZ010000017.1  16039792-16039879
            1155-1261           JAXUCZ010000017.1  16040246-16040352
            1262-1353           JAXUCZ010000017.1  16040741-16040832
            1354-1443           JAXUCZ010000017.1  16042114-16042203
            1444-1803           JAXUCZ010000017.1  16042673-16043032
            1804-1923           JAXUCZ010000017.1  16044190-16044309
            1924-2039           JAXUCZ010000017.1  16044667-16044782
            2040-2218           JAXUCZ010000017.1  16046777-16046955
            2219-2289           JAXUCZ010000017.1  16047054-16047124
            2290-2450           JAXUCZ010000017.1  16047789-16047949
            2451-2722           JAXUCZ010000017.1  16051946-16052217
            2723-2818           JAXUCZ010000017.1  16053319-16053414
            2819-2928           JAXUCZ010000017.1  16053909-16054018
            2929-3316           JAXUCZ010000017.1  16054601-16054988
            3317-5248           JAXUCZ010000017.1  16055652-16057583
FEATURES             Location/Qualifiers
     source          1..5248
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="17"
                     /map="17p14"
     gene            1..5248
                     /gene="Phf2"
                     /note="PHD finger protein 2"
                     /db_xref="GeneID:306814"
                     /db_xref="RGD:1305228"
     exon            1..212
                     /gene="Phf2"
                     /inference="alignment:Splign:2.1.0"
     CDS             115..3405
                     /gene="Phf2"
                     /codon_start=1
                     /product="lysine-specific demethylase PHF2"
                     /protein_id="NP_001402072.1"
                     /db_xref="GeneID:306814"
                     /db_xref="RGD:1305228"
                     /translation="MATVPVYCVCRLPYDVTRFMIECDACKDWFHGSCVGVEEEEAPD
                     IDIYHCPNCEKTHGKSTLKKKRTWHKHGPGQTPDMKPVQNGSQLFIKELRSRTFPSAE
                     DVVSRVPGSQLTVGYMEEHGFTEPILVPKKDGLGLAVPAPTFYVSDVENYVGPERSVD
                     VTDVTKQKDCKMKLKEFVDYYYSTNRKRVLNVTNLEFSDTRMSSFVEPPDIVKKLSWV
                     ENYWPDDALLAKPKVTKYCLICVKDSYTDFHIDSGGASAWYHVLKGEKIFYLIRPASA
                     NLSLYECWRSASNHSEMFFADQVDKCYKCTVKQGQTLFIPSGWIYATLTPVDCLAFAG
                     HFLHSLSVEMQMRAYEVERRLKLGSLTQFPNFETACWYMGKHLLEAFKGSHKSGKQLP
                     PHLVQGAKILNGAFRSWTKKQALAEHEDELPEHFRPSQLIKDLAKEIRLSENASKTVR
                     PEVNAVASSDEVCDGDREKEEPPSPIESTPPRSLLEKVSKKKTSKTVKMPKPSKTPKP
                     PKPPKPPKTLKLKDGSKKKGKKCKESASPTIPNLDLLEAHTKEALTKMEPPKKGKTPK
                     SVLSVPNKDTVHTQNDVERLEIREQTKSKSEAKWKYKNSKPDSLLRMEEEQRLEKSPL
                     AGNKDKFSFSFSNRKLLGSKPLRPPSSPGVFGTLQSFKEDKAKPVRDEYEYVSDDGEL
                     KIDEFPIRRKKNPPKRDLSFLLDKKETLLIPTSKPKLDSTAYKSDDSSDEGSLHIDTD
                     TKPSRNAKVKKESGSSAAGILDLLQASEEVGALEYNPNSQPPASPSTQEAIQGMLSMA
                     NLQASDSCLQTTWGTGQAKGGSLAAHGARKNGGSSKGTGKRLLKRTAKNSVDLEDYEE
                     QDHLDACFKDSDYVYPSLESDEDNPVFKSRSKKRKGSDDAPYSPTARVGPSVPRQDRP
                     VREGTRVASIETGLAAAAAKLSQQEEQKNRKKKNTKRKPTPNTASPSVSTSASASTGT
                     TSASTTPASTTPASTTPASTTPASTSTASSQASQEGSSPEPPPESHSSGLADHEYTAA
                     GTFAGAQAGRASQPMAPGVFLTQRRPSASSPNNTAAKGKRTKKGMATAKQRLGKILKI
                     HRNGKLLL"
     exon            213..298
                     /gene="Phf2"
                     /inference="alignment:Splign:2.1.0"
     exon            299..413
                     /gene="Phf2"
                     /inference="alignment:Splign:2.1.0"
     exon            414..574
                     /gene="Phf2"
                     /inference="alignment:Splign:2.1.0"
     exon            575..716
                     /gene="Phf2"
                     /inference="alignment:Splign:2.1.0"
     exon            717..903
                     /gene="Phf2"
                     /inference="alignment:Splign:2.1.0"
     exon            904..1066
                     /gene="Phf2"
                     /inference="alignment:Splign:2.1.0"
     exon            1067..1154
                     /gene="Phf2"
                     /inference="alignment:Splign:2.1.0"
     exon            1155..1261
                     /gene="Phf2"
                     /inference="alignment:Splign:2.1.0"
     exon            1262..1353
                     /gene="Phf2"
                     /inference="alignment:Splign:2.1.0"
     exon            1354..1443
                     /gene="Phf2"
                     /inference="alignment:Splign:2.1.0"
     exon            1444..1803
                     /gene="Phf2"
                     /inference="alignment:Splign:2.1.0"
     exon            1804..1923
                     /gene="Phf2"
                     /inference="alignment:Splign:2.1.0"
     exon            1924..2039
                     /gene="Phf2"
                     /inference="alignment:Splign:2.1.0"
     exon            2040..2218
                     /gene="Phf2"
                     /inference="alignment:Splign:2.1.0"
     exon            2219..2289
                     /gene="Phf2"
                     /inference="alignment:Splign:2.1.0"
     exon            2290..2450
                     /gene="Phf2"
                     /inference="alignment:Splign:2.1.0"
     exon            2451..2722
                     /gene="Phf2"
                     /inference="alignment:Splign:2.1.0"
     exon            2723..2818
                     /gene="Phf2"
                     /inference="alignment:Splign:2.1.0"
     exon            2819..2928
                     /gene="Phf2"
                     /inference="alignment:Splign:2.1.0"
     exon            2929..3316
                     /gene="Phf2"
                     /inference="alignment:Splign:2.1.0"
     exon            3317..5248
                     /gene="Phf2"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gctccggccg cggcgcccgc gcccgccgcc cccgccgccc tcgccgcgcg gcccccggcc
       61 cggcccggcc cgacccgggc agcgcagcgg cggggcgagc ggcggcgcgg caacatggcg
      121 acggtgcccg tgtactgcgt ctgccggctg ccctacgacg ttacccgctt catgatcgag
      181 tgcgatgcct gcaaggactg gttccacggc agctgtgttg gggtggaaga ggaagaggca
      241 ccagacatcg acatttacca ctgcccgaac tgcgagaaaa cccatggcaa gtccacgctc
      301 aagaaaaagc ggacctggca caagcatggc cctgggcaga caccggacat gaagccagtg
      361 cagaatggca gccagctgtt catcaaggag ctgcggagcc gaaccttccc cagtgctgaa
      421 gatgtggtgt cccgtgtacc aggcagccag ctcactgtgg gctacatgga ggagcatggc
      481 ttcaccgagc ccatccttgt ccccaagaaa gatggcctgg gcttggctgt ccctgcccca
      541 acattctacg tgagtgacgt ggagaactat gtggggccag agaggagtgt ggacgtgaca
      601 gacgttacca agcagaaaga ctgcaaaatg aagctgaaag aattcgtgga ctattactac
      661 agcaccaacc gcaaacgtgt tctcaatgtg accaacctcg agttctcaga caccagaatg
      721 tccagctttg tggagccacc tgacattgtg aagaaactat cgtgggtgga aaactactgg
      781 cccgatgacg cgctgctggc caagcccaag gtgaccaagt actgcctgat ctgtgtgaag
      841 gacagctaca ccgacttcca cattgattct ggaggtgcct cagcctggta ccacgttctc
      901 aagggggaga agatcttcta tctcatccgg ccggcctcag ccaacctctc cctatatgaa
      961 tgctggcggt cagcctccaa ccacagcgag atgttctttg ctgaccaggt ggacaagtgc
     1021 tataagtgca ctgtcaagca gggccagacc ctcttcatcc cctcaggctg gatatacgct
     1081 acgctcaccc ctgtggactg cctggccttc gctggacatt ttcttcacag cctcagtgtg
     1141 gagatgcaga tgagggcata cgaggtggaa agaaggttaa aactaggcag cctgactcaa
     1201 tttcccaact ttgaaactgc ctgctggtac atggggaagc atctattgga agcattcaaa
     1261 ggttctcaca agtctgggaa acagctgccc ccacacttag ttcaaggagc taagattctc
     1321 aatggtgctt ttaggtcatg gacgaagaag caggctttgg cagagcacga ggacgagctc
     1381 ccggagcact tcaggccctc acagctcatc aaggacctgg ccaaagagat caggctcagc
     1441 gagaatgcct ccaaaactgt ccgacctgaa gtaaatgctg tcgcctcctc agatgaggtc
     1501 tgtgacgggg accgggagaa ggaggaaccg ccatctccca ttgagtctac cccacctcga
     1561 tccctcctgg agaaagtgtc caaaaaaaag acttccaaga ctgtgaagat gcccaagcca
     1621 tccaaaaccc ccaagccccc caagcccccc aagcccccca aaaccctgaa actcaaggac
     1681 ggaagcaaga agaaagggaa gaagtgcaaa gagtccgcct ctcccaccat ccccaacttg
     1741 gacctgcttg aggcccacac caaggaggcg ctgaccaaga tggagccacc gaagaaagga
     1801 aagactccaa agagcgtcct gagtgttccc aataaggaca cggtccacac gcagaatgac
     1861 gtggaaagac tggaaatccg agagcaaaca aagagcaagt cggaggccaa gtggaagtac
     1921 aagaacagca aacctgactc tttactgaga atggaggagg agcagaggtt ggagaagtca
     1981 cccctggctg ggaacaagga caagttttcc ttttctttct ctaacagaaa actcctgggc
     2041 tccaagcccc tcaggccgcc gagcagccct ggcgtgttcg ggaccttgca gagcttcaag
     2101 gaggacaagg ccaagcccgt ccgagatgag tatgaatatg tatcggacga cggggagctg
     2161 aagattgacg agtttcctat caggaggaag aagaaccccc ccaaaaggga tttgtccttt
     2221 ttgttagaca agaaggagac tctcctcatc cccacctcga agccaaagct ggactccacg
     2281 gcatacaaga gcgacgactc ctctgatgag ggctctctgc atatcgacac ggacaccaag
     2341 ccaagccgaa atgccaaagt gaagaaggaa agtgggagct cggcggcagg catcctggac
     2401 ctactgcagg ccagcgagga ggtcggggct cttgagtaca accccaacag ccagccccct
     2461 gcctccccca gtacgcagga agccattcag ggaatgttgt ccatggccaa tctgcaggcc
     2521 tctgactcct gcctgcagac cacatggggc actggccagg ccaagggggg ttccctggca
     2581 gcccatggcg cccggaagaa tggtggtagc agcaaaggga caggcaagcg cctactgaag
     2641 aggactgcca agaacagcgt ggatcttgag gactatgagg agcaggacca cctggacgcc
     2701 tgcttcaagg actcagacta tgtttacccc tcactggagt ctgacgaaga taaccctgtc
     2761 ttcaagtccc ggtcaaagaa gaggaaaggc tcagacgatg ctccttacag ccccacagcc
     2821 agggtcggtc catcagtgcc gagacaagac aggcctgtgc gtgaggggac cagagtggcc
     2881 tccattgaga ctgggctggc agctgctgca gccaagctgt cccagcagga ggagcagaaa
     2941 aacaggaaga agaagaacac caaaaggaag ccgactccta acactgcctc cccctccgtc
     3001 tccacgtctg cctccgcctc cacgggtacc acctcggcct ccaccacccc agcctccacc
     3061 accccggcct ccaccacccc agcatccacc accccggcct ctaccagcac agccagcagc
     3121 caggcctcac aggagggcag ctcacccgag cccccacctg agtcacacag cagtggccta
     3181 gctgaccacg agtatacagc agccggcaca ttcgcagggg cccaggctgg ccgtgcctcc
     3241 cagcccatgg cccctggagt ctttctcaca cagaggcggc cttctgcatc atcccccaac
     3301 aacactgctg ccaaaggaaa acgtacaaaa aagggcatgg ccaccgccaa gcaaaggctt
     3361 ggaaagatct tgaagatcca tcggaatggg aaactgctcc tctaaggctt ggaaagccag
     3421 gatccttctg ctctgctcag gacccccgga gccccgctac atcagcccct cccaggacgg
     3481 tggctgtgcc gcctggcccg gggagggcct tgcctcctcc cagccacctc tccccaatgc
     3541 gagcatctgt cccttgagca ggtggaatga gcggagcatg gccgtccctt gttgtgaaca
     3601 cggacatcct ttctcagttg ctcagagtga cctgaaagtg gccctgccga cctaaggatc
     3661 attctggttt caggacagcc tccaggctcc ccaccggagc ctggcgacct ctatggctct
     3721 gcttgggagc atgaggcctt caaggaaggt gcggtgagcc acgctcacca gcctgagtcc
     3781 gagctggccc caggctggca gcctcccaag gcataaaaca aggcaaagga cagagaaaga
     3841 gaggagctgt ggggcaacga gcgtcccctc cctcctctac ctgagcgagt cttacagcac
     3901 ttgatcagtg aggagaggtt gccccagctc cctggctggc aggtagcagg ctaggtagtg
     3961 ggtgtcacac cccaaaaggc ctagggacat ttgggcttgt caggacctgc agttaggttg
     4021 gtgtgtgagt gggtggagga gccactgtgg gttcacaggg gaagggtgac agctcagcca
     4081 cgtcttaggg tccgggggac ccaggctaag ccacgtggag gggccccact ctggaacagc
     4141 acttctaggc caaggcaccc tgccctgagt gggcagacag cagggccaca gggctggagc
     4201 cagcatggca gcgttgtctg agcccctggg tggcatcatg agtgtggcca tctcaggtgg
     4261 cggtgtccac ccatcaacat ggaggggctg ggtttgtttc tcaggcaatc ctgtattttc
     4321 attttagatg tatttccgga agcatatttt taatagaatg tagcgtgtaa atagcttttt
     4381 aaatgacttc ttttttacaa gagcaaaagt atctctaggg atttctttct atagagccct
     4441 tcattaacct ttatacgagt ttttgctccc ccaccccttc tctgacggat ggtcaggttc
     4501 cggctccccc accccctttg ctttcctttc ctttcctttt gttactcctt cttattttcc
     4561 tcttaggaac taaggtattg cctgaaaaac aacggcgcct gcgcggcctt accctctgtc
     4621 tctcagagcg gatagtacgg attccctccc cactcgccct gaagccgcgt ctccagtctc
     4681 acaccagctc ttcgatctcc ttcttgtgtg acgagggccg gggacgcagt tactttgcta
     4741 gcaccttgtg aagtatttgt gtttcgtgat gctgtaattt attaatgttt gtagcttttt
     4801 atatttgtac atttcttatg aggtttgttt ctacacccgt tacctggatg tgttgtccac
     4861 gaggagatgc agcttggtgg aggccttatc cactcccact ttgacctgtt tggagggacg
     4921 tcatccccag ggcccggggc tgggagaggg gcatcttgca ggccccaggc ttactcagaa
     4981 ctggtgtttt taaagtttcc ttgacctgtc cttgtgaaca tttctataat cttaacccgg
     5041 gcatcaagct gttctctctc tctctctttt tctcttttta attttattat tattttggca
     5101 acatgtacat ttctaacaaa gtttatcgtg gctattaaag tgttctattt cccagttcat
     5161 attactcttg tatcgagtcc atgaggtcta aggcgactta gaccaaagtt ttaaaaaaaa
     5221 agtaaaaata tttcaggttt tgtacaga
//
