LOCUS       NM_001106570            3789 bp    mRNA    linear   ROD 22-MAR-2023
DEFINITION  Rattus norvegicus PHD finger protein 19 (Phf19), mRNA.
ACCESSION   NM_001106570 XM_001080221 XM_231165
VERSION     NM_001106570.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3789)
  AUTHORS   Gu W, Cheng Y, Wang S, Sun T and Li Z.
  TITLE     PHD Finger Protein 19 Promotes Cardiac Hypertrophy via
            Epigenetically Regulating SIRT2
  JOURNAL   Cardiovasc Toxicol 21 (6), 451-461 (2021)
   PUBMED   33611744
  REMARK    GeneRIF: PHD Finger Protein 19 Promotes Cardiac Hypertrophy via
            Epigenetically Regulating SIRT2.
REFERENCE   2  (bases 1 to 3789)
  AUTHORS   Herz HM, Garruss A and Shilatifard A.
  TITLE     SET for life: biochemical activities and biological functions of
            SET domain-containing proteins
  JOURNAL   Trends Biochem Sci 38 (12), 621-639 (2013)
   PUBMED   24148750
  REMARK    Review article
REFERENCE   3  (bases 1 to 3789)
  AUTHORS   Lu R and Wang GG.
  TITLE     Tudor: a versatile family of histone methylation 'readers'
  JOURNAL   Trends Biochem Sci 38 (11), 546-555 (2013)
   PUBMED   24035451
  REMARK    Review article
REFERENCE   4  (bases 1 to 3789)
  AUTHORS   Simon JA and Kingston RE.
  TITLE     Occupying chromatin: Polycomb mechanisms for getting to genomic
            targets, stopping transcriptional traffic, and staying put
  JOURNAL   Mol Cell 49 (5), 808-824 (2013)
   PUBMED   23473600
  REMARK    Review article
REFERENCE   5  (bases 1 to 3789)
  AUTHORS   Cai L, Rothbart SB, Lu R, Xu B, Chen WY, Tripathy A, Rockowitz S,
            Zheng D, Patel DJ, Allis CD, Strahl BD, Song J and Wang GG.
  TITLE     An H3K36 methylation-engaging Tudor motif of polycomb-like proteins
            mediates PRC2 complex targeting
  JOURNAL   Mol Cell 49 (3), 571-582 (2013)
   PUBMED   23273982
REFERENCE   6  (bases 1 to 3789)
  AUTHORS   Patel DJ and Wang Z.
  TITLE     Readout of epigenetic modifications
  JOURNAL   Annu Rev Biochem 82, 81-118 (2013)
   PUBMED   23642229
  REMARK    Review article
REFERENCE   7  (bases 1 to 3789)
  AUTHORS   Brien GL, Gambero G, O'Connell DJ, Jerman E, Turner SA, Egan CM,
            Dunne EJ, Jurgens MC, Wynne K, Piao L, Lohan AJ, Ferguson N, Shi X,
            Sinha KM, Loftus BJ, Cagney G and Bracken AP.
  TITLE     Polycomb PHF19 binds H3K36me3 and recruits PRC2 and demethylase
            NO66 to embryonic stem cell genes during differentiation
  JOURNAL   Nat Struct Mol Biol 19 (12), 1273-1281 (2012)
   PUBMED   23160351
REFERENCE   8  (bases 1 to 3789)
  AUTHORS   Ballare C, Lange M, Lapinaite A, Martin GM, Morey L, Pascual G,
            Liefke R, Simon B, Shi Y, Gozani O, Carlomagno T, Benitah SA and Di
            Croce L.
  TITLE     Phf19 links methylated Lys36 of histone H3 to regulation of
            Polycomb activity
  JOURNAL   Nat Struct Mol Biol 19 (12), 1257-1265 (2012)
   PUBMED   23104054
REFERENCE   9  (bases 1 to 3789)
  AUTHORS   Hunkapiller J, Shen Y, Diaz A, Cagney G, McCleary D, Ramalho-Santos
            M, Krogan N, Ren B, Song JS and Reiter JF.
  TITLE     Polycomb-like 3 promotes polycomb repressive complex 2 binding to
            CpG islands and embryonic stem cell self-renewal
  JOURNAL   PLoS Genet 8 (3), e1002576 (2012)
   PUBMED   22438827
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH474001.2.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_001080221.1, XM_231165.4.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMD00132261,
                              SAMD00132263 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..3789
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="3"
                     /map="3p11"
     gene            1..3789
                     /gene="Phf19"
                     /note="PHD finger protein 19"
                     /db_xref="GeneID:296653"
                     /db_xref="RGD:1310390"
     exon            1..45
                     /gene="Phf19"
                     /inference="alignment:Splign:2.1.0"
     exon            46..231
                     /gene="Phf19"
                     /inference="alignment:Splign:2.1.0"
     CDS             52..1788
                     /gene="Phf19"
                     /codon_start=1
                     /product="PHD finger protein 19"
                     /protein_id="NP_001100040.1"
                     /db_xref="GeneID:296653"
                     /db_xref="RGD:1310390"
                     /translation="METQALEPGTQEAFGATSPNKGAPSKTKKNFKDLMSKVTEGQFV
                     LCRWTDGLYYLGKIKRVSSPKQSCLVTFEDNSKYWVLWKDIQHAGVPGEEPKCDVCMG
                     KTSGPMNEILICGKCGLGYHQQCHIPIAVDANWPLLTHWFCRRCIFALAVRKGGALKK
                     GAIAKTLQAVKMVLSYQPEELDWDSPHRTNQQQCYCYCGGPGEWYLRMLQCYRCRQWF
                     HEACTQCLSEPMVFGDRFYLFFCSVCNQGPEYIERLPLRWVDIVHLALYNLGVQSKKR
                     YFDFEEILAFVNHHWELLQLGKLTSTPVTERGPHLLNALNSYKSRFLCGKEIKKKKCI
                     FRLRVRVPPAPPGKLLPDRAQMPSDKGTFELLRKRGKSKPGLLPQESQQQKRRVYRRK
                     RSKFLLEDAIPSSDFTSAWSTDHHLASIFDFTLDEIQSLKSGSSGQTFFSDVDSTDAA
                     STSGSASTSLSQDSRWTVGSRKRKLAAKAYRPLRAKHRAAEPDGRCASDSSAEGAPGP
                     EQQDEGIDSHTFESISGDDSSLSHLKSSITNYFGAAGRLACGEKYQVLARRVTPEGKV
                     QYLLEWEGTTPY"
     exon            232..313
                     /gene="Phf19"
                     /inference="alignment:Splign:2.1.0"
     exon            314..409
                     /gene="Phf19"
                     /inference="alignment:Splign:2.1.0"
     exon            410..510
                     /gene="Phf19"
                     /inference="alignment:Splign:2.1.0"
     exon            511..659
                     /gene="Phf19"
                     /inference="alignment:Splign:2.1.0"
     exon            660..755
                     /gene="Phf19"
                     /inference="alignment:Splign:2.1.0"
     exon            756..824
                     /gene="Phf19"
                     /inference="alignment:Splign:2.1.0"
     exon            825..945
                     /gene="Phf19"
                     /inference="alignment:Splign:2.1.0"
     exon            946..1013
                     /gene="Phf19"
                     /inference="alignment:Splign:2.1.0"
     exon            1014..1175
                     /gene="Phf19"
                     /inference="alignment:Splign:2.1.0"
     exon            1176..1263
                     /gene="Phf19"
                     /inference="alignment:Splign:2.1.0"
     exon            1264..1349
                     /gene="Phf19"
                     /inference="alignment:Splign:2.1.0"
     exon            1350..1445
                     /gene="Phf19"
                     /inference="alignment:Splign:2.1.0"
     exon            1446..3789
                     /gene="Phf19"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 tggtggccag actccaagtg ggaccggctg acgcgctgcc tcgcgaagct gatggagacg
       61 caagctctgg aaccagggac tcaggaagcc tttggtgcca ccagccctaa caagggggcc
      121 ccgtctaaga ccaaaaagaa cttcaaagac ttgatgtcta aggtgacaga gggacagttt
      181 gtgctatgcc ggtggactga cgggctatac taccttggca agatcaagcg ggtcagcagt
      241 cctaagcaaa gctgcctcgt gactttcgaa gacaattcca aatactgggt cctttggaag
      301 gacatccagc atgctggtgt tccaggagag gagcccaagt gtgatgtctg catggggaag
      361 acttcaggac cgatgaacga gatcctcatc tgtgggaagt gtggcctggg ttaccaccaa
      421 cagtgccaca tccccatagc agtcgatgcc aactggcccc tcctcactca ctggttctgc
      481 cgacgctgca ttttcgcact ggctgtgagg aaaggcggtg cgctgaagaa aggcgccatc
      541 gccaagacgc tgcaggcagt gaaaatggtg ctgtcctacc agcctgagga gctcgattgg
      601 gattcgcccc atcgcaccaa ccagcagcaa tgctactgct actgcggcgg gcctggagag
      661 tggtacttac ggatgctaca gtgctaccgg tgtaggcagt ggttccatga agcctgtaca
      721 cagtgcctaa gtgagcctat ggtgtttgga gaccggttct acctgttctt ctgctccgtg
      781 tgtaaccaag gcccagagta tatcgagagg ttgcccctga gatgggtaga catagttcac
      841 ctggccctct ataacctggg agtacagagc aagaagaggt acttcgactt tgaggagatc
      901 ctggcctttg tcaaccacca ctgggagctc ctgcagcttg gcaagctcac gagcacccct
      961 gtgacagagc gagggccgca tctcctcaac gctctcaaca gttacaaaag ccggttcctg
     1021 tgtggcaagg agattaagaa gaagaaatgc atcttccgac tgcgcgtccg tgtcccgccc
     1081 gcccctccag gaaaactgct tccggacagg gcacagatgc caagtgacaa agggaccttt
     1141 gagctgcttc gtaagagagg aaagagcaag cctggtttgt tgcctcagga atcccagcag
     1201 cagaaaaggc gagtttatag aagaaaaaga tcaaagtttt tgctggaaga tgctattccc
     1261 agtagtgact tcacctcagc ctggagcacg gaccaccacc tggccagcat attcgacttt
     1321 acactggatg aaattcagag tttaaaaagt ggcagctcag gccagacctt cttctcagac
     1381 gtggattcta ccgatgctgc tagcacctca ggctctgcgt ccaccagcct ctcccaggac
     1441 tccagatgga cagtaggcag ccgtaagagg aagctggcgg ccaaagcgta caggcccctg
     1501 cgggcaaagc atcgggcagc cgagccggat gggagatgcg cctcagacag cagtgcagag
     1561 ggagctccgg gccctgagca gcaggatgaa ggcatcgaca gccacacgtt cgaaagcatc
     1621 agtggagatg actcctccct gtcccatctc aagtcctcta tcaccaacta cttcggtgca
     1681 gctgggcggt tggcctgcgg ggaaaagtat caggtgttgg ctcggagggt cactccagaa
     1741 ggcaaggttc agtacctgtt ggaatgggag ggcactaccc cttactgatt atccctcaga
     1801 ggctgcccag aggctgcaaa ccaaaggagg ggcagaagaa gcccctgggt ccctgttttc
     1861 tccaggctta cggtggtgga gggaagcagg acatcctggc cgcagcccct gcctgctgtc
     1921 tgccaggcca aggtctgtgt gctgctgtac cagttgcccg agtctctgag gccctgctgg
     1981 ctctctctcg tctatatcac actccatacc ctcaaacttt ccattggttc ctccgatggt
     2041 accctggctg tgacccctga tctgaggcct gaaactgatt ttcgttgtcc ccagttctcc
     2101 atcttctgac ctctcccctg cttgggtgtt tcatgcggac acacatcttc catgcacata
     2161 tgctcatctg tccctcactg ggaccacagt gaggaaaggg aaccctgtgg gtcttccact
     2221 ttctcaccag tacccctcac ccaggagagt aggggatgcc tgagaaagtt caggatgcct
     2281 gcgacccaga gcctgggaag tgatggcctg ggtctctact gaagggacga gaatcagggt
     2341 cttttattga ggctgggaag ggggactaag ggagtcaagg ccaaggctcc cagaagtttg
     2401 cctgtcccca gcaacagctc ttcactgttg ccgcagacta gagcctggcc ttgctacata
     2461 gacgtgttct tgaacgcgca gatctgggag gaaacgatgg ggaggaccca tcccaaacac
     2521 tgtgtataca gacaaacacc accacacatc cccaccaggg tgccctggcc ctgtccttgg
     2581 cctcttccag ggataaatgc tgcagttaaa tgtgaaaacc aagctccggc ctcctctggc
     2641 ctgtgaacca gccttggccc cacagagaag cacaaaagac accccaagac acccctctcc
     2701 tgcatagctc ctgccttgcc cagaagctga caatcacttt ggggatgggg cagccggggg
     2761 cggggagaga gggcagttcc caagggtctg aatcattggt tcccttcaga aaggaagtct
     2821 ttgtcatcga tggtaaaata gaattcttag aatggacaaa ctcagccgtg tccggaggga
     2881 aaccaaaact aggaggtagg cagggagtcc ttatttttgc ctgcagaaac agaaactgac
     2941 tcgctcggtt ggacaattag aaagaagtgc ctttggggtg ggaggcaggg gcaccagact
     3001 gggaccagct tccctgactg ctgctgtggc ttctggctgg gagtggggaa atggaccatc
     3061 gcatggcgac atcagactat atcagaagtg ctgatttccc catgagtggg tctgacccct
     3121 ccacatccac ctgtgagcat taaggaggag ggggagtccc tgaggtaggc tagacggtcc
     3181 ctgccataca cctcagcaac catagtgcct tgcaaaggaa cctcacctct cactagacac
     3241 agctacccac gtccatctgc ttccccgtct tggctcaggc agggctcagc agatggacac
     3301 tgagaccagt tctcagtccc acagctgctg ccactgaggt ccccaagtgg gtcccggtgg
     3361 aaggagagtt gtaaagccaa ctcccaggcc agcaggcatg tgggaactgg ggtcaagttt
     3421 gtggcttcct gttggcttct gtgagcacgg caacctccaa catgtgtttt ccaggctact
     3481 ggggaagcca gagagtttag gatggctgtt tgtacatctg tccctcctcc cctgctgtgc
     3541 cccagaagct ctaggcctga ggagcaggaa ggcaggtggg gtgctcatcc cgctggggaa
     3601 gctagcacaa ggcctgacca ggtcctggac tcctcaaggc agcatttcac ccctacatga
     3661 caatagctgc attactgcca accgatggta cgaccctgtg cacctttgaa gagattctgg
     3721 ttttaaattg ctgcttttaa tagtatttgt tatattaaag ttataattga cgtgtctggt
     3781 ttacaacat
//
