LOCUS       XM_039099503            7084 bp    mRNA    linear   ROD 11-JUN-2023
DEFINITION  PREDICTED: Rattus norvegicus phosphate regulating endopeptidase
            X-linked (Phex), transcript variant X1, mRNA.
ACCESSION   XM_039099503
VERSION     XM_039099503.1
DBLINK      BioProject: PRJNA677964
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_051356.1) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            [WARNING] On Feb 22, 2024 this sequence was replaced by
            XM_039099503.2.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_015227675.2-RS_2023_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/06/2023
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7084
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN/NHsdMcwi"
                     /db_xref="taxon:10116"
                     /chromosome="X"
                     /sex="male"
                     /tissue_type="kidney"
                     /geo_loc_name="USA: Wisconsin, Milwaukee, Medical College
                     of Wisconsin"
                     /collection_date="2019-03-08"
                     /collected_by="Rebecca Schilling"
     gene            1..7084
                     /gene="Phex"
                     /gene_synonym="PEX"
                     /note="phosphate regulating endopeptidase X-linked;
                     Derived by automated computational analysis using gene
                     prediction method: Gnomon. Supporting evidence includes
                     similarity to: 11 ESTs, 10 Proteins, and 98% coverage of
                     the annotated genomic feature by RNAseq alignments,
                     including 2 samples with support for all annotated
                     introns"
                     /db_xref="GeneID:25512"
                     /db_xref="RGD:3323"
     CDS             1626..3875
                     /gene="Phex"
                     /gene_synonym="PEX"
                     /codon_start=1
                     /product="phosphate-regulating neutral endopeptidase PHEX
                     isoform X1"
                     /protein_id="XP_038955431.1"
                     /db_xref="GeneID:25512"
                     /db_xref="RGD:3323"
                     /translation="MEAEAGSTMETGKGTNRGIRIALALFITGTLVLGTLLFLVSQGL
                     LSFQAKQEYCLKPECIEAAAAIMSKVNLSVDPCENFFRFACDGWISNNPIPEDMPSYG
                     VYPWLRHNVDLKLKALLEKSVSRRRDTEAVQKAKILYSSCMNEKAIEKADAKPLLHIL
                     RHSPFRWPVLEANIGPEGVWSERKFSLLQTLATFRGQYSNSVFIRLYVSPDDKASNEH
                     ILKLDQATLSLAVREDFLDNTTEAKSYRDALYKFMVDTAVLLGANSSRAEHDMKSVLR
                     LEIKIAEIMIPHENRTSEAMYNKMNISELSAMIPQFDWLGYIKKVIDTRLYPHLKDIG
                     PSENVVVRVPQYFKDLFRILGAERKKTIANYLVWRMVYSRIPNLSRRFQYRWLEFSRV
                     IQGTTTLLPQWDKCVNFIESALPYVVGKMFVNVHFQEDKKEMMEELIEGVRWAFIDML
                     EKENEWMDAGTKRKAQEKARAVLAKVGYPEFIMNDTYVNEDLKAIKFSESDYFGNVLQ
                     TRKYLAQSDFFWLRKAVPKTEWFTNPTTVNAFYSASTNQIRFPAGELQKPFFWGTEYP
                     RSLSYGAIGVIVGHEFTHGFDNNGRKYDKNGNLDPWWSVDSEEKFKEKTKCMINQYSN
                     YYWKKAGLNVKGKRTLGENIADNGGLREAFRAYRKWINDRRQGVEEPLLPGITFTNNQ
                     LFFLSYAHVRCNSYRPEAAREQVQIGAHSPPQFRVNGAISNFEEFQKAFNCPANSTMN
                     RGADSCRLW"
ORIGIN      
        1 ggcgtttggt gttttcctct ggcgtcagag atgtgtgcct caagtatacc tgaggccagt
       61 tgaccattat tgaatttcta gttttacttc ttgttttttt ttttttttca tgagtttttg
      121 catgtggcca cgaactgaga aagtgtcaag agacttcttt gatttgctaa ttaattgcat
      181 ttaagaccca acctggtttg gaatgttttt atttgaaaca agtgcatgta tatcatgctg
      241 tcaacaaatt taccctgcag aaatcgccag ttaactcatt ttcatggctc tgtaggagta
      301 gtcttttttg gacaatcccc ttcctgtgaa taatgacttt ccattctcca acacacaggg
      361 taatattcta gagtctcatt attgtagttt cagataaaga tccattcttc aatttccttg
      421 acacaatggt ttctattcca cgagcataga ttggagcaat tttgagttgc aggtcagcat
      481 gggttttgta tgtcatttga agaggtagca tttctttctc tctctctctc tctctctctc
      541 tctctctctc tctgtctctc tctctctctc tctctctctt tatttttttt ttttgtcccc
      601 taatgggctg gagagtaaaa cattctaagc ttcacagaga aaaatgtttg ccacagaacc
      661 atagaacctt tgaccatgta gcatgaatgg agccataagt gatctgacaa aaccattaac
      721 cgaaacagag aataaaccag attgggctga taatgtactt tcttttacag ccctcttctt
      781 tgaccttttg tgaacactca ttattcagct gtaccttgaa cttatttctt ttggcctaag
      841 gtattttgtc atcctaattt gtttttaagt gcctttattt tcagtacaag ataatcacga
      901 tctcccaaaa ggctgagaaa ttaatgcaga aaatgacaca taatgaagaa tgcgccttat
      961 aaggaatgat acacccacac cctgtcctcc gtcaatcgca cccactctca aatgttcctt
     1021 taatttcttt ggtgagtaaa aggagcctac attacattac attatattca gcaaactatt
     1081 tttaacaact tgagagctgt gtttttactt ccatagagtt attttcatga atcaagtgca
     1141 ttcttttcta cacacgtcta agtttggaac ggaaagcatc aagttttcta ttactatcat
     1201 tggaagtgtg tttattgtat tggtgtcctt ttctttctct ctctctctct ttctttcttt
     1261 ctttctttct tccttctttc ttttttttct cagatattaa acgttcagga atgaagtcct
     1321 gtctgcaaat gactagtggg tggaacttca atggaacttc caaatctctc tcacttctgg
     1381 ggatttacca gtctaaggtt cctgaatcat cctcccatac tcccaccatc ttctgacctc
     1441 tgcctagata ggcacaagat tatttgagaa agtgtgtcga ggggaagttt cctgacagga
     1501 atttttaaag ctgtctatta gcagacgagc aagagagtct tgaatgtcaa atgcctgaca
     1561 aactcttgag accagccacc aaaccacgaa aagtgacttt ctgagtcttc tcttcggccc
     1621 ttctgatgga agcagaagca gggagcacca tggagactgg aaaggggacc aaccgaggca
     1681 ttcggattgc actggccctg ttcattactg gcaccctggt gctgggcaca ctgctctttc
     1741 tagtgagtca aggtctccta agtttccaag ctaaacagga gtactgcctg aagccagaat
     1801 gcattgaagc cgctgctgcc atcatgagca aagtaaatct ttctgtggat ccttgtgaga
     1861 attttttccg gtttgcttgt gatggctgga taagcaataa cccaattcct gaagatatgc
     1921 caagctatgg ggtttatcct tggctgagac acaatgttga cctcaagttg aaggcacttc
     1981 tggagaaatc agtcagtcga aggcgggaca ctgaagctgt acagaaagcc aaaatccttt
     2041 attcatcctg catgaatgag aaagcgattg aaaaagcaga tgccaaacca ctgctccaca
     2101 tcttgaggca ttcacctttc cgctggcccg tgcttgaagc taatattggt cctgaagggg
     2161 tttggtcaga gagaaaattc agtctactgc aaacactggc aacattccgc ggtcaataca
     2221 gcaattctgt gttcatccgt ttgtacgtgt cccctgacga caaggcatcc aatgagcata
     2281 tcttgaagtt ggaccaagca acactctccc tggctgtgag ggaagacttt ctggataaca
     2341 ctaccgaagc caaatcttat cgtgatgccc tttacaaatt catggtggac actgctgtgc
     2401 ttttaggagc taatagctct cgagctgaac atgacatgaa gtcagtgctt agactggaaa
     2461 ttaagatagc tgagataatg attccacatg agaaccgaac cagtgaggct atgtataaca
     2521 aaatgaacat ctcagagctc agtgctatga ttccccagtt tgactggctg ggctatatca
     2581 agaaggtcat tgataccaga ctctacccac acttgaaaga cattggcccc tcggagaatg
     2641 tggtggtgcg cgtcccacaa tactttaaag atttgtttag gatattaggt gctgaaagga
     2701 agaaaaccat tgccaactat ttggtgtgga gaatggttta ttccagaatt ccaaacctca
     2761 gcaggcgctt tcaatataga tggctggaat tctcaagggt aatccagggg acaacaactc
     2821 tgctgcctca gtgggacaaa tgtgttaact ttatcgaaag tgccctccct tatgttgtgg
     2881 ggaaaatgtt tgtgaatgtt cacttccagg aagataagaa ggaaatgatg gaagaattga
     2941 ttgagggtgt tcgctgggcc ttcattgaca tgctggagaa agaaaatgaa tggatggatg
     3001 cagggacaaa aaggaaagct caagaaaagg caagagctgt tttggcaaaa gttggctatc
     3061 cagagtttat aatgaatgat acttatgtta atgaagacct caaggcaatc aaattttcag
     3121 aatcggacta ctttggcaac gtactgcaaa cccgcaagta tttagcacag tctgatttct
     3181 tctggctaag aaaagctgtt cccaaaacag agtggtttac aaacccaaca acggtcaatg
     3241 ccttttacag tgcatctacc aaccagatac gatttcctgc tggagagctg cagaagcctt
     3301 tcttttgggg aacagaatac cctcgatctc tgagttacgg tgctatagga gtaattgtgg
     3361 ggcacgaatt tacacatgga tttgataata atggtagaaa atatgataaa aatggaaacc
     3421 ttgatccgtg gtggtctgtg gactctgaag aaaagtttaa ggaaaaaaca aaatgcatga
     3481 ttaaccagta tagcaactat tattggaaga aagccggctt aaatgtgaag gggaaaagga
     3541 ccttgggaga aaatattgct gataatggag gtcttcgaga agcttttagg gcttacagga
     3601 aatggataaa tgatagaaga cagggagttg aagagcccct cctaccaggc atcacattca
     3661 ccaacaatca gctcttcttc ctgagttatg ctcacgtgag gtgcaattcc tacagaccgg
     3721 aagctgccag agaacaagtc caaattggtg ctcacagtcc tccacaattt agagtcaatg
     3781 gtgccattag caactttgaa gaatttcaga aagcttttaa ctgtccggca aattccacca
     3841 tgaacagagg tgcagattcc tgccgactct ggtagctgga gtgctggttt ctgccatcct
     3901 gacagagctg aggagtgccg gtagaggagg cactcacata ctcagcacct actgcttttt
     3961 gcctatattt tgtcgaagac ttttattttt aatgcatttc tattatttgg gtagatgatt
     4021 tgcttggatc taaacagtat ctgttcaaag tcattgggtt tataaaagga atgcaagaac
     4081 tgagggaaat acatcttttt aaagtaagcc aaaccaatga aaacaagtgt caaggctatt
     4141 tggttaaact gctcttggct gatctcccct atcatccctt tatgttagcc acggctaggt
     4201 ggtacctaac atttcaatct atagctctgc agggggcctg aggagagtgt atccatagaa
     4261 aggatcagtc aatgaaaatt gtcaccctca gtgataaagt tgtgtgccct ttggtgtaca
     4321 gtgattatac aacatttctt aattctaagg tggttaaatt agaaatacgt tggaccttca
     4381 ttttacagtt tatgataaag tttttctctt caggtttgga gtctattgga caattatctc
     4441 agaactttct tcagatgtag ctaactgccc tgtttaagta atcatgaaca aagatggcat
     4501 acagtcaatt tggtaaagga tttgggtcta taaaataggg aaaaagaaca catctttaac
     4561 tgccagcagt attaaaaact attaaccacc acaataacaa ctaatcacac aacaataaag
     4621 ataataggaa atgaaatctg caaacgttga tccagtccct ccatacatca gtggacatct
     4681 atctgacgga taacaatcat ggagcagttc tgattttgtt ttgttctgct cagatatcct
     4741 gactgaactg agtagatatt gaggaaataa tattccgttt ccatgtcagg aacatatggt
     4801 tttcatttcc tttcagcatg atgatataat caccacactg aggatggagt aaaaagcctc
     4861 ttccttctca gccactttat gttacctctc cttaaaagaa aatttttgca aaagtttcta
     4921 gaaagaaagc attttggtat atatgaatcc aatttaagca atcctgtcta gatctaaagg
     4981 acataacttt actcttcaag tcttatgaag ggtttaattt ttctaaaaac agtactgtat
     5041 tttgatcttt agagcattat ttttgtaatc atcacctata gtgttaatta attaacagta
     5101 ttagtgtgta tttatgtagg ataactgtta tcacatttaa gagtgtatgt aggataaaat
     5161 tataatggca ttgaagtggt gagtatttcc tgtttttttc tattgtttta aaaattagta
     5221 tagccatttt tctacccccc cattacataa ttcattatac atggggtgct gggttaagtg
     5281 ggccaataga aaaacttcaa aagcaaaatg acaaaatcag atgaaccaca ggacttcatt
     5341 ttgcatcctt gtgacttgtc attcttttgc aaaaaaaaaa aaaaaaagta agtgtgaacc
     5401 atatcctttt gtaaccatgg gaacttccaa agagagaaaa atggaagggc accatcatga
     5461 ggaaaacaat tacactgcat tagtctgagg agagtgattt tccccttgac ttcctcctct
     5521 ccgaatggat acacttctga agggcagcag ccttttcctc cgcttaacca tggtttaatg
     5581 tgaccttggt ttgtatttct aataacaaac agcattatgt gagatgttag aaatatgtgt
     5641 gccttttctc tggtgtaacc attctgattt gataatcctc attttactcc tgaacactga
     5701 agtttgctat gcttatataa atagtgggtt ccttctaggt ttcctttttt aacaattcca
     5761 aagaaacaca ttcctgcagg tcagagagag tgtttgataa aactacagac ttatgacttt
     5821 ggaaatggta ttggtttatt ggttaaggac agctggttag tgatcagtta gagttctccc
     5881 agtttctgga tgacaagatt agtaactaag tatcttgatc aacttaagat tttcaagaga
     5941 tactaaattc ttcttgtagc cacatacatc ttctacaagt actaactttt taagtgtttc
     6001 tgttaaacct ttcaaatcac aatactgttc tctgtgtgac ttggtttctt aaagagacac
     6061 cgattaaatg atagagaagg tcagacatga gtggaggaat ggaagtgtgg caagcagggg
     6121 gagctggcct aaggaaacaa gacaggatct tggtcctcct tgatgtacat gttcactgga
     6181 ggaaagtcag aaagttttta aaaataatta tggtaaatca aaaggaaatt aaatattgga
     6241 tctcagacta gggctgcagc aacacactgc tctgactcat ataacagctg ttctgcaagt
     6301 ggattattaa ctgggccttt gaaggagttt ttagttcttt ttaatgtgtg ggaaattctc
     6361 tttcgtgagt cagagatttg gtatatctaa agctgtgttg tttggcctta ctaccattgt
     6421 ccaaagtttg ctgagttttt cactaagcat aggcctccta ttcctgactc actccctttt
     6481 atgagatgga ttggtacacg actgctgtaa aatgagaatt cataaattat ccctgagctt
     6541 atttagtgcc ttacctcaat ggagcttaaa gcatagccca taaattttat cttatttagc
     6601 cctggagcat cactaagacg aaactaggaa ccaaggctca ccagacagag ggtgctcatg
     6661 ccaagaggaa tgggaaggct tagaattgct tatcaaatat ctcagagcat gggaagacag
     6721 gttttgtgct ttgggctact gacctttgaa ttaacttgca tctcttagaa gatcttcttt
     6781 tctgatatgt ttattccacc agtatttcta aagttactta tcatttggta gccactgcct
     6841 ttgatatttt ttaacataat gtcacagtac accttaaatt atggaaaact gcatgattgt
     6901 ttcatgtaat aacatcttta tcactagtgg cagtgcctta ctggttttaa gaaagatgtc
     6961 cttggatttg cagtttaaaa acaatctatg ttgctactat cagactggtt tggttgtgat
     7021 ttttttcctt tgtgaaacaa ggacaatcat cattttaagg acaataaaac atttgttgaa
     7081 ggtt
//
