LOCUS       NM_001107662            3415 bp    mRNA    linear   ROD 24-JUN-2024
DEFINITION  Rattus norvegicus polyhomeotic homolog 3 (Phc3), mRNA.
ACCESSION   NM_001107662 XM_001058534 XM_001058585 XM_001058644 XM_226976
VERSION     NM_001107662.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3415)
  AUTHORS   Gil,J. and O'Loghlen,A.
  TITLE     PRC1 complex diversity: where is it taking us?
  JOURNAL   Trends Cell Biol 24 (11), 632-641 (2014)
   PUBMED   25065329
  REMARK    Review article
REFERENCE   2  (bases 1 to 3415)
  AUTHORS   Simon,J.A. and Kingston,R.E.
  TITLE     Occupying chromatin: Polycomb mechanisms for getting to genomic
            targets, stopping transcriptional traffic, and staying put
  JOURNAL   Mol Cell 49 (5), 808-824 (2013)
   PUBMED   23473600
  REMARK    Review article
REFERENCE   3  (bases 1 to 3415)
  AUTHORS   Vandamme,J., Volkel,P., Rosnoblet,C., Le Faou,P. and Angrand,P.O.
  TITLE     Interaction proteomics analysis of polycomb proteins defines
            distinct PRC1 complexes in mammalian cells
  JOURNAL   Mol Cell Proteomics 10 (4), M110.002642 (2011)
   PUBMED   21282530
REFERENCE   4  (bases 1 to 3415)
  AUTHORS   Maertens,G.N., El Messaoudi-Aubert,S., Racek,T., Stock,J.K.,
            Nicholls,J., Rodriguez-Niedenfuhr,M., Gil,J. and Peters,G.
  TITLE     Several distinct polycomb complexes regulate and co-localize on the
            INK4a tumor suppressor locus
  JOURNAL   PLoS One 4 (7), e6380 (2009)
   PUBMED   19636380
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 3415)
  AUTHORS   Deshpande,A.M., Akunowicz,J.D., Reveles,X.T., Patel,B.B.,
            Saria,E.A., Gorlick,R.G., Naylor,S.L., Leach,R.J. and Hansen,M.F.
  TITLE     PHC3, a component of the hPRC-H complex, associates with E2F6
            during G0 and is lost in osteosarcoma tumors
  JOURNAL   Oncogene 26 (12), 1714-1722 (2007)
   PUBMED   17001316
REFERENCE   6  (bases 1 to 3415)
  AUTHORS   Girard,A., Sachidanandam,R., Hannon,G.J. and Carmell,M.A.
  TITLE     A germline-specific class of small RNAs binds mammalian Piwi
            proteins
  JOURNAL   Nature 442 (7099), 199-202 (2006)
   PUBMED   16751776
REFERENCE   7  (bases 1 to 3415)
  AUTHORS   Levine,S.S., Weiss,A., Erdjument-Bromage,H., Shao,Z., Tempst,P. and
            Kingston,R.E.
  TITLE     The core of the polycomb repressive complex is compositionally and
            functionally conserved in flies and humans
  JOURNAL   Mol Cell Biol 22 (17), 6070-6078 (2002)
   PUBMED   12167701
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473961.1.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_001058644.1, XM_001058585.1, XM_226976.4, XM_001058534.1.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMEA5760393,
                              SAMN09345330 [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..3415
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="2"
                     /map="2q24"
     gene            1..3415
                     /gene="Phc3"
                     /note="polyhomeotic homolog 3"
                     /db_xref="GeneID:310258"
                     /db_xref="RGD:1307998"
     exon            1..170
                     /gene="Phc3"
                     /inference="alignment:Splign:2.1.0"
     exon            171..326
                     /gene="Phc3"
                     /inference="alignment:Splign:2.1.0"
     exon            327..399
                     /gene="Phc3"
                     /inference="alignment:Splign:2.1.0"
     CDS             385..2877
                     /gene="Phc3"
                     /note="polyhomeotic like 3"
                     /codon_start=1
                     /product="polyhomeotic-like protein 3"
                     /protein_id="NP_001101132.1"
                     /db_xref="GeneID:310258"
                     /db_xref="RGD:1307998"
                     /translation="MSQTSINLSTSPTPAQLMSRSQASSSTSGSITQQTMLLGSTSPT
                     LTASQAQMYLRAQMVQNLTLRSQKLGVLSSSQNGPPKSAGQTQSLTICHNKTTVTSSK
                     ISQRDPSPESKKGGSPGLESRSTAVTRTSSIHQLIAPASYSPIQPHSLIKHQQIPLHS
                     PPPKVSHHQLILQQQQQQIQPITLQSPSQDPPPSQHCIPLPNHGLSPASSNAQSQQHC
                     SPIQSHPPPLTVSPSQAQSAQQSVVVSPPPAHSPSQSPTIIIHPQALVQPHPLVSSAL
                     HTGPNLQQATADQVQSTAQLNLPSHLPLPASPVVHIGPVQQSALVSPGQQIVSPTSHQ
                     QYSTLQSSPIPIATPPQMSASPPAQIPPLPLQSMQSLQVQPEILSQGQVLVQNALVSE
                     EELPAAEALVQLPFQTLPPPQTVAVNLQVQPPAPVDPPVVYQVEDVCEEERPEESDEC
                     ARMDRTPPPPTLSPAAITVGRGEDLTSEHPLLEQVELPAVASVSASVIKSPSDPTHVS
                     APAPPLLMPAASTRSSSTSLASSTPSLENKPPQAIVKPQILTHVIEGFVIQEGLEPFP
                     VSRSSLLIEQPVKKRPLLDNQVVNSVCVQPELQNNTKHADNSSDTEMEDMIAEETLEE
                     MDSELLKCEFCGKMGYPNEFLRSKRFCTMSCAKRYNVSCSKKFALSRWNRKPDNQSLG
                     HRGRRPSGPEGAAREHILRQLPITYPSAEEDLASRDDPVPSAMTTRLRRQSERERERE
                     LRDVRIRKMPENSDLLPVAQTEPSIWTVDDVWAFIHSLPGCQDVADEFRAQEIDGQAL
                     LLLKEDHLMSTMNMKLGPALKICARINSLKDS"
     exon            400..558
                     /gene="Phc3"
                     /inference="alignment:Splign:2.1.0"
     exon            559..802
                     /gene="Phc3"
                     /inference="alignment:Splign:2.1.0"
     exon            803..1677
                     /gene="Phc3"
                     /inference="alignment:Splign:2.1.0"
     exon            1678..1831
                     /gene="Phc3"
                     /inference="alignment:Splign:2.1.0"
     exon            1832..2082
                     /gene="Phc3"
                     /inference="alignment:Splign:2.1.0"
     exon            2083..2242
                     /gene="Phc3"
                     /inference="alignment:Splign:2.1.0"
     exon            2243..2357
                     /gene="Phc3"
                     /inference="alignment:Splign:2.1.0"
     exon            2358..2490
                     /gene="Phc3"
                     /inference="alignment:Splign:2.1.0"
     exon            2491..2722
                     /gene="Phc3"
                     /inference="alignment:Splign:2.1.0"
     exon            2723..3415
                     /gene="Phc3"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ctaccagatt taaagaccac agtacagcta tggagagtga gcccagctct ggaacgtctg
       61 tgtcaacaac agccagcagc accaccacca ccaccatcac cacatcctcc tcccgaatgc
      121 agcagccaca gatctctgtc tacagtgggt cagaccgaca tgctgtccag gtaattcagc
      181 aggccctgca tcggcccccc agctcggcag ctcagtacct gcagcagatg tacgcagcgc
      241 agcagcagca cctcatgctg cacacggccg cccttcagca gcagcatctg agcagctccc
      301 agctccagag cctggcggcc gtgcagtttg tccagtggaa gaccatctac atcccccaca
      361 ggcagtgtta cacaacagtc aagtatgtcc cagacatcta tcaacctctc cacttcgccg
      421 acacctgctc agctgatgag ccgctcgcag gcctccagct cgaccagtgg cagcattacc
      481 cagcagacca tgctcctagg gagcacctcg cccaccctca cagccagcca ggcccaaatg
      541 tatctccgag ctcaaatggt tcagaattta acattacgca gccagaagtt gggtgtctta
      601 tctagctcac agaatggccc accaaaaagt gctggtcaaa cccagtcctt gacaatttgc
      661 cataataaaa caacagtgac cagttctaaa atcagccaac gagacccttc tccagagagc
      721 aagaagggcg gaagtccagg tctggaatct cggagcacag ccgtcacacg gacatcaagc
      781 attcaccagt tgatagcacc agcttcatat tctccaattc agcctcattc tctaatcaaa
      841 catcaacaga ttcctctcca ttcaccacct cctaaagttt cccatcatca gctgatatta
      901 caacagcaac aacagcaaat tcagccaatc acccttcaga gtccaagtca agatccaccc
      961 ccatcccagc actgtatccc actccccaac catggccttt ctccggcttc cagtaatgcc
     1021 cagtcacagc agcattgctc accaattcag agccatcccc cgcctttaac tgtgtctcct
     1081 agccaggccc agtctgcaca gcagtctgta gtggtgtctc ctccccccgc tcattcccca
     1141 agccagtctc ctaccatcat tatccatcca caagcacttg tccagccaca ccctcttgtg
     1201 tcttcagctc ttcacacagg gccaaacttg cagcaggcca ctgctgatca ggtacaatcc
     1261 acagcacagc tgaacctccc gtcccatctt ccacttccag catcccctgt agtacacatt
     1321 ggccccgtcc agcagtctgc cttggtgtcc cctggtcagc agatagtgtc cccaacatca
     1381 caccagcaat attcaaccct acagtcatct ccaattccga tcgcaacccc tccacagatg
     1441 tcggcatctc ctccagctca gatcccacca ctgcccttgc agtctatgca gtctttacaa
     1501 gtgcagcctg aaattctatc ccagggccag gttttggtgc agaatgcttt ggtgtcagaa
     1561 gaggagctgc ctgctgcaga agctttggtc cagttgccat ttcagactct tcctcctcca
     1621 cagaccgttg cggtaaacct acaagtacag ccgccagcac ctgttgatcc accagtggtt
     1681 tatcaggtag aagatgtgtg cgaggaagaa aggccagagg agtccgatga gtgtgcacgg
     1741 atggaccgaa caccgccgcc ccccactttg tctccagcag ctatcactgt ggggagagga
     1801 gaggatttga catctgagca tcctttgtta gagcaagtag agttgcctgc cgtggcctca
     1861 gtcagtgctt ctgtgatcaa gtctccatca gacccaaccc atgtctctgc tcctgcacct
     1921 ccactcttaa tgcccgctgc ctccacaagg agcagcagca cttctctggc cagcagcacc
     1981 cccagcctgg aaaacaagcc tccacaggct atcgtgaagc cacagattct gacccacgtt
     2041 atagaaggtt ttgtgattca ggagggactg gagccgtttc ctgtgagtcg ttcatctttg
     2101 ctgatagaac aacctgtgaa aaagaggcct cttttggata atcaggtggt aaattcggtg
     2161 tgtgttcagc cagagctaca gaataacaca aagcatgcag ataactcgtc cgacacagag
     2221 atggaggaca tgattgctga agagacattg gaagaaatgg atagtgagtt actcaagtgt
     2281 gaattctgtg gaaaaatggg atatcctaat gaatttttac gatcaaaacg attctgtact
     2341 atgtcatgtg ccaaaaggta caacgttagc tgttctaaaa agtttgcact tagtcgttgg
     2401 aatcgtaagc ctgataatca aagtcttggg catcggggcc gtcgtccaag tggccctgaa
     2461 ggggcagcga gagaacatat ccttaggcag cttccaatta cttatccatc tgcagaagaa
     2521 gacttggcct ctcgtgacga tcctgtgccg tctgctatga cgactcgcct gcgcaggcag
     2581 agtgagcggg aaagagaacg cgaacttcgc gacgtgagga ttaggaaaat gcctgagaac
     2641 agcgacttgc tcccagtcgc acagacggag ccctccatat ggacggtcga tgacgtctgg
     2701 gccttcatcc actctttgcc tggctgtcag gacgttgccg atgagttcag ggcacaggag
     2761 attgatgggc aggcactgct cctgctaaaa gaagaccatc tcatgagcac aatgaacatg
     2821 aagctgggcc cagccctgaa gatctgtgca cgcatcaact ctctgaagga ctcctaacag
     2881 cagccaggct ttgtctcagt ccattcctct ttctcggtga aggtaaagcc tgatggggct
     2941 gagagcatcg gactgatggg ggaaggccaa gtgcattggg accgccacgg ccagtgccga
     3001 catttctctt cagatgccct aactcatctt atgttctcat aattagcgac cgtcggtggt
     3061 gttaatttta ccagttacag actacactga aagacttgtt acagaggccc atatttttca
     3121 aagaaacatg ttatactaga taatttttta aaggtaatgt ttatcattaa tataaaagaa
     3181 tccttttaaa aataattatt gatttacact ccccctcctt taattctctt ttcttataca
     3241 tttgtctacc ctgttagttt tctaaatgtt gtcatagaga tataggataa tttaggagcc
     3301 cattgacaga attgaatgca atgaaatagc agtatgtttt taaaagtatc ttccacagat
     3361 gctttggttg tgaaatggga ttgtgtttta gcataaggag tatttttgaa ggttc
//
