LOCUS       NP_001101132             830 aa            linear   ROD 24-JUN-2024
DEFINITION  polyhomeotic-like protein 3 [Rattus norvegicus].
ACCESSION   NP_001101132 XP_001058534 XP_001058585 XP_001058644 XP_226976
VERSION     NP_001101132.1
DBSOURCE    REFSEQ: accession NM_001107662.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (residues 1 to 830)
  AUTHORS   Gil,J. and O'Loghlen,A.
  TITLE     PRC1 complex diversity: where is it taking us?
  JOURNAL   Trends Cell Biol 24 (11), 632-641 (2014)
   PUBMED   25065329
  REMARK    Review article
REFERENCE   2  (residues 1 to 830)
  AUTHORS   Simon,J.A. and Kingston,R.E.
  TITLE     Occupying chromatin: Polycomb mechanisms for getting to genomic
            targets, stopping transcriptional traffic, and staying put
  JOURNAL   Mol Cell 49 (5), 808-824 (2013)
   PUBMED   23473600
  REMARK    Review article
REFERENCE   3  (residues 1 to 830)
  AUTHORS   Vandamme,J., Volkel,P., Rosnoblet,C., Le Faou,P. and Angrand,P.O.
  TITLE     Interaction proteomics analysis of polycomb proteins defines
            distinct PRC1 complexes in mammalian cells
  JOURNAL   Mol Cell Proteomics 10 (4), M110.002642 (2011)
   PUBMED   21282530
REFERENCE   4  (residues 1 to 830)
  AUTHORS   Maertens,G.N., El Messaoudi-Aubert,S., Racek,T., Stock,J.K.,
            Nicholls,J., Rodriguez-Niedenfuhr,M., Gil,J. and Peters,G.
  TITLE     Several distinct polycomb complexes regulate and co-localize on the
            INK4a tumor suppressor locus
  JOURNAL   PLoS One 4 (7), e6380 (2009)
   PUBMED   19636380
  REMARK    Publication Status: Online-Only
REFERENCE   5  (residues 1 to 830)
  AUTHORS   Deshpande,A.M., Akunowicz,J.D., Reveles,X.T., Patel,B.B.,
            Saria,E.A., Gorlick,R.G., Naylor,S.L., Leach,R.J. and Hansen,M.F.
  TITLE     PHC3, a component of the hPRC-H complex, associates with E2F6
            during G0 and is lost in osteosarcoma tumors
  JOURNAL   Oncogene 26 (12), 1714-1722 (2007)
   PUBMED   17001316
REFERENCE   6  (residues 1 to 830)
  AUTHORS   Girard,A., Sachidanandam,R., Hannon,G.J. and Carmell,M.A.
  TITLE     A germline-specific class of small RNAs binds mammalian Piwi
            proteins
  JOURNAL   Nature 442 (7099), 199-202 (2006)
   PUBMED   16751776
REFERENCE   7  (residues 1 to 830)
  AUTHORS   Levine,S.S., Weiss,A., Erdjument-Bromage,H., Shao,Z., Tempst,P. and
            Kingston,R.E.
  TITLE     The core of the polycomb repressive complex is compositionally and
            functionally conserved in flies and humans
  JOURNAL   Mol Cell Biol 22 (17), 6070-6078 (2002)
   PUBMED   12167701
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473961.1.
            
            On or before Oct 4, 2007 this sequence version replaced
            XP_001058644.1, XP_001058585.1, XP_226976.3, XP_001058534.1.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMEA5760393,
                              SAMN09345330 [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..830
                     /organism="Rattus norvegicus"
                     /db_xref="taxon:10116"
                     /chromosome="2"
                     /map="2q24"
     Protein         1..830
                     /product="polyhomeotic-like protein 3"
                     /note="polyhomeotic like 3"
                     /calculated_mol_wt=89746
     Region          <108..513
                     /region_name="PHA03247"
                     /note="large tegument protein UL36; Provisional"
                     /db_xref="CDD:223021"
     Region          <188..>353
                     /region_name="PAT1"
                     /note="Topoisomerase II-associated protein PAT1;
                     pfam09770"
                     /db_xref="CDD:401645"
     Region          761..829
                     /region_name="SAM_Ph1,2,3"
                     /note="SAM domain of Ph (polyhomeotic) proteins of
                     Polycomb group; cd09577"
                     /db_xref="CDD:188976"
     Site            order(779..780,814..815,818..819,822)
                     /site_type="other"
                     /note="oligomer interface EH [polypeptide binding]"
                     /db_xref="CDD:188976"
     Site            order(790..794,796..797,800..801,805,810)
                     /site_type="other"
                     /note="oligomer interface ML [polypeptide binding]"
                     /db_xref="CDD:188976"
     CDS             1..830
                     /gene="Phc3"
                     /coded_by="NM_001107662.1:385..2877"
                     /db_xref="GeneID:310258"
                     /db_xref="RGD:1307998"
ORIGIN      
        1 msqtsinlst sptpaqlmsr sqassstsgs itqqtmllgs tsptltasqa qmylraqmvq
       61 nltlrsqklg vlsssqngpp ksagqtqslt ichnkttvts skisqrdpsp eskkggspgl
      121 esrstavtrt ssihqliapa syspiqphsl ikhqqiplhs pppkvshhql ilqqqqqqiq
      181 pitlqspsqd pppsqhcipl pnhglspass naqsqqhcsp iqshpppltv spsqaqsaqq
      241 svvvspppah spsqsptiii hpqalvqphp lvssalhtgp nlqqatadqv qstaqlnlps
      301 hlplpaspvv higpvqqsal vspgqqivsp tshqqystlq sspipiatpp qmsasppaqi
      361 pplplqsmqs lqvqpeilsq gqvlvqnalv seeelpaaea lvqlpfqtlp ppqtvavnlq
      421 vqppapvdpp vvyqvedvce eerpeesdec armdrtpppp tlspaaitvg rgedltsehp
      481 lleqvelpav asvsasviks psdpthvsap appllmpaas trssstslas stpslenkpp
      541 qaivkpqilt hviegfviqe glepfpvsrs sllieqpvkk rplldnqvvn svcvqpelqn
      601 ntkhadnssd temedmiaee tleemdsell kcefcgkmgy pneflrskrf ctmscakryn
      661 vscskkfals rwnrkpdnqs lghrgrrpsg pegaarehil rqlpitypsa eedlasrddp
      721 vpsamttrlr rqsererere lrdvrirkmp ensdllpvaq tepsiwtvdd vwafihslpg
      781 cqdvadefra qeidgqalll lkedhlmstm nmklgpalki carinslkds
//
