LOCUS       NP_620609                422 aa            linear   ROD 19-NOV-2024
DEFINITION  phagosome assembly factor 1 [Rattus norvegicus].
ACCESSION   NP_620609
VERSION     NP_620609.2
DBSOURCE    REFSEQ: accession NM_139040.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (residues 1 to 422)
  AUTHORS   Stricker,N.L. and Huganir,R.L.
  TITLE     The PDZ domains of mLin-10 regulate its trans-Golgi network
            targeting and the surface expression of AMPA receptors
  JOURNAL   Neuropharmacology 45 (6), 837-848 (2003)
   PUBMED   14529721
  REMARK    GeneRIF: Lin-10 is enriched in the trans-Golgi network and present
            in dendrites and spines of whole brain and cultured neurons--where
            protein sorting and synaptic delivery are known to
            occur--suggesting that Lin-10 may regulate AMPA receptor
            trafficking in vivo.
REFERENCE   2  (residues 1 to 422)
  AUTHORS   Ide,N., Hata,Y., Hirao,K., Irie,M., Deguchi,M., Yao,I., Satoh,A.,
            Wada,M., Takahashi,K., Nakanishi,H. and Takai,Y.
  TITLE     Interaction of rat lin-10 with brain-enriched F-actin-binding
            protein, neurabin-II/spinophilin
  JOURNAL   Biochem Biophys Res Commun 244 (1), 258-262 (1998)
   PUBMED   9514910
REFERENCE   3  (residues 1 to 422)
  AUTHORS   Ide,N., Hirao,K., Hata,Y., Takeuchi,M., Irie,M., Yao,I.,
            Deguchi,M., Toyoda,A., Nishioka,H., Mizoguchi,A. and Takai,Y.
  TITLE     Molecular cloning and characterization of rat lin-10
  JOURNAL   Biochem Biophys Res Commun 243 (2), 634-638 (1998)
   PUBMED   9480860
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000019.1.
            
            On Dec 3, 2020 this sequence version replaced NP_620609.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: U92010.1, SRR26643291.41632.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..422
                     /organism="Rattus norvegicus"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="19"
                     /map="19q11"
     Protein         1..422
                     /product="phagosome assembly factor 1"
                     /note="lin-10 homolog; UPF0183 protein C16orf70 homolog"
                     /calculated_mol_wt=47333
     Region          15..407
                     /region_name="PHAF1"
                     /note="Phagosome assembly factor 1; pfam03676"
                     /db_xref="CDD:461013"
     CDS             1..422
                     /gene="Phaf1"
                     /gene_synonym="Lin-10; Lin10; RGD621098"
                     /coded_by="NM_139040.2:197..1465"
                     /db_xref="GeneID:207123"
                     /db_xref="RGD:621098"
ORIGIN      
        1 mldlevvper slgneqweft lgmplaqava ilqkhcriik nvqvlyseqs plshdlilnl
       61 tqdgikllfd afnqrlkvie vydltkvklk ycgvhfnsqa iaptieqidq sfgathpgvy
      121 nsaeqlfhln frglsfsfql dswteapkye pnfahglasl qiphgatvkr myiysgnslq
      181 dtkapmmpls cflgnvyaes vdvlrdgtgp sglrlrllaa gcgpgvlada kmrvferavy
      241 fgdscqdvls mlgsphkvfy ksedkmkihs psphkqvpsk cndyffnyft lgvdilfdan
      301 thkvkkfvlh tnypghynfn iyhrcefkip laikkenagg qteicttysk wdsiqellgh
      361 pvekpvvlhr ssspnntnpf gstfcfglqr mifevmqnnh iasvtlygpp rpgahlrtae
      421 lp
//
