LOCUS       NM_214458               1776 bp    mRNA    linear   ROD 24-JUN-2024
DEFINITION  Rattus norvegicus phosphatase and actin regulator 2 (Phactr2),
            mRNA.
ACCESSION   NM_214458 XM_218094
VERSION     NM_214458.2
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1776)
  AUTHORS   Chiocco,M.J., Zhu,X., Walther,D., Pletnikova,O., Troncoso,J.C.,
            Uhl,G.R. and Liu,Q.R.
  TITLE     Fine mapping of calcineurin (PPP3CA) gene reveals novel alternative
            splicing patterns, association of 5'UTR trinucleotide repeat with
            addiction vulnerability, and differential isoform expression in
            Alzheimer's disease
  JOURNAL   Subst Use Misuse 45 (11), 1809-1826 (2010)
   PUBMED   20590401
REFERENCE   2  (bases 1 to 1776)
  AUTHORS   Goldstein,B.A., Hubbard,A.E., Cutler,A. and Barcellos,L.F.
  TITLE     An application of Random Forests to a genome-wide association
            dataset: methodological considerations & new findings
  JOURNAL   BMC Genet 11, 49 (2010)
   PUBMED   20546594
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 1776)
  AUTHORS   Wider,C., Lincoln,S.J., Heckman,M.G., Diehl,N.N., Stone,J.T.,
            Haugarvoll,K., Aasly,J.O., Gibson,J.M., Lynch,T., Rajput,A.,
            Rajput,M.L., Uitti,R.J., Wszolek,Z.K., Farrer,M.J. and Ross,O.A.
  TITLE     Phactr2 and Parkinson's disease
  JOURNAL   Neurosci Lett 453 (1), 9-11 (2009)
   PUBMED   19429005
REFERENCE   4  (bases 1 to 1776)
  AUTHORS   Allen,P.B., Greenfield,A.T., Svenningsson,P., Haspeslagh,D.C. and
            Greengard,P.
  TITLE     Phactrs 1-4: A family of protein phosphatase 1 and actin regulatory
            proteins
  JOURNAL   Proc Natl Acad Sci U S A 101 (18), 7187-7192 (2004)
   PUBMED   15107502
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from
            JAXUCZ010000001.1.
            
            On Nov 27, 2020 this sequence version replaced NM_214458.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AY500158.1, SRR26643298.147.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760383,
                                           SAMEA5760393 [ECO:0006172]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-53                JAXUCZ010000001.1  9530860-9530912     c
            54-221              JAXUCZ010000001.1  9497140-9497307     c
            222-302             JAXUCZ010000001.1  9468266-9468346     c
            303-461             JAXUCZ010000001.1  9463224-9463382     c
            462-1008            JAXUCZ010000001.1  9454995-9455541     c
            1009-1211           JAXUCZ010000001.1  9448660-9448862     c
            1212-1368           JAXUCZ010000001.1  9447057-9447213     c
            1369-1424           JAXUCZ010000001.1  9441551-9441606     c
            1425-1486           JAXUCZ010000001.1  9435618-9435679     c
            1487-1624           JAXUCZ010000001.1  9433972-9434109     c
            1625-1701           JAXUCZ010000001.1  9426874-9426950     c
            1702-1776           JAXUCZ010000001.1  9418085-9418159     c
FEATURES             Location/Qualifiers
     source          1..1776
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1p13"
     gene            1..1776
                     /gene="Phactr2"
                     /note="phosphatase and actin regulator 2"
                     /db_xref="GeneID:308291"
                     /db_xref="RGD:1303141"
     exon            1..53
                     /gene="Phactr2"
                     /inference="alignment:Splign:2.1.0"
     CDS             8..1717
                     /gene="Phactr2"
                     /codon_start=1
                     /product="phosphatase and actin regulator 2"
                     /protein_id="NP_999623.2"
                     /db_xref="GeneID:308291"
                     /db_xref="RGD:1303141"
                     /translation="MGQTSVSALSPQPGSVDGLDKASIANSDGPPAGSQTPPFKRKGK
                     LSTIGKIFKPWKWRKKKTSDKFRETSAVLERKISTRQSREELIRRGLLKELPDQDGDV
                     TVNFENSNGHMIHIGEEATQEENVGKPEEGNVSVCEKGPPREEQAEEKTAGSSHPKKT
                     TGSKASSSPSASSTSSHPRGPKESLTGKAGAVGTTRGKKKISKQPAAAASRLSPNTVT
                     SETSSLKGELSDTGVESLKPEETVAGAEEEATGKPKAVVVALPPVTVPPSSPALPLPP
                     EDPCTIALDTPMVLVSDGPTLPISALETSPLPGTEEPANRTTPYSSTGLGGSREQAKC
                     FTTKDGPGKAGPQLLTPGQMGDSLESFSAPEDEAPREYQANDSDSDGPILYTDDDDEE
                     DDDDDSTGESALASKIRRRDTLAIKLGNRPSKKELEDKNILQRTSEEERQELRQQIGT
                     KLVRRLSQRPTTEELEQRNILKQKNEEEEQEAKMELKRRLSRKLSLRPTVAELQARRI
                     LRFNEYVEVTDSPDYDRRADKPWARLTPADKAAIRKELNEFKSTEMEVHEESRQFTRF
                     HRP"
     exon            54..221
                     /gene="Phactr2"
                     /inference="alignment:Splign:2.1.0"
     exon            222..302
                     /gene="Phactr2"
                     /inference="alignment:Splign:2.1.0"
     exon            303..461
                     /gene="Phactr2"
                     /inference="alignment:Splign:2.1.0"
     exon            462..1008
                     /gene="Phactr2"
                     /inference="alignment:Splign:2.1.0"
     exon            1009..1211
                     /gene="Phactr2"
                     /inference="alignment:Splign:2.1.0"
     exon            1212..1368
                     /gene="Phactr2"
                     /inference="alignment:Splign:2.1.0"
     exon            1369..1424
                     /gene="Phactr2"
                     /inference="alignment:Splign:2.1.0"
     exon            1425..1486
                     /gene="Phactr2"
                     /inference="alignment:Splign:2.1.0"
     exon            1487..1624
                     /gene="Phactr2"
                     /inference="alignment:Splign:2.1.0"
     exon            1625..1701
                     /gene="Phactr2"
                     /inference="alignment:Splign:2.1.0"
     exon            1702..1776
                     /gene="Phactr2"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 acccgccatg ggccagacct cggtgtccgc gctgtccccg cagcccggca gcgttgatgg
       61 actagacaaa gcctccatag caaactcaga tggcccccca gcaggttccc agacacctcc
      121 cttcaagaga aaggggaaac tctccaccat tggtaaaatc ttcaagcctt ggaaatggag
      181 gaaaaagaag accagtgaca agtttagaga gacctcagca gtattagaga ggaagatatc
      241 caccagacaa agtagagagg agctgataag aaggggcctg cttaaggaat tgcctgatca
      301 agatggagat gtaacagtta actttgaaaa ttcaaacggg cacatgatac acatcggaga
      361 ggaagctacc caagaggaga atgtagggaa acctgaagaa gggaatgtct ctgtgtgtga
      421 gaaaggacca cctcgagagg aacaggcaga agagaagaca gctggttcct ctcacccgaa
      481 gaaaacaact ggttccaaag cctcatcctc accatctgct tcgtccacct cctctcatcc
      541 cagaggaccc aaggagtcac tcactggcaa agcaggcgcg gttgggacca caaggggcaa
      601 gaaaaagatt agcaagcagc cagcagcggc ggcatcccga ctgtccccca acacagtcac
      661 ttctgaaacg tctagtctta aaggagagct ctcagacact ggggtagaga gcctcaagcc
      721 agaggaaact gttgctggag cagaggagga ggccacaggc aaacccaagg cggtcgtcgt
      781 cgctctgcca cctgtcacag taccgccatc ttcacctgcc cttcctctgc cccctgagga
      841 tccatgcact attgccttgg acactcccat ggtcctagtc agtgatggac ccaccctgcc
      901 catctctgcc ttagaaacaa gtccgctccc tgggactgaa gaaccagcga acagaaccac
      961 tccgtactca agcaccggct taggtgggag ccgagagcag gcaaaatgtt ttacaaccaa
     1021 agatgggccg ggaaaggctg gacctcaatt gctgacccct ggacagatgg gagactcatt
     1081 agaatccttc agtgccccag aggatgaggc cccaagagag taccaagcca atgactctga
     1141 ctcggatgga cccatcttat acacagatga tgatgatgaa gaagatgatg atgatgacag
     1201 cactggagaa agtgcattgg caagtaagat cagacgaagg gatacactcg ccatcaaact
     1261 tggcaacaga ccatccaaga aagagctaga ggacaaaaac atcctgcagc gaacgtctga
     1321 agaagaaagg caggagctgc gacaacagat cggaaccaag ctggtcagga gactcagcca
     1381 gaggccaacc actgaagaat tagagcagag aaacatctta aaacaaaaga atgaagaaga
     1441 ggagcaggaa gcaaaaatgg aactcaaacg gaggctcagc cggaagctca gcctaagacc
     1501 tactgtggca gagctacaag cccgaagaat cctgcggttt aatgagtatg tggaagtcac
     1561 agattccccg gactacgaca gacgtgcgga caagccctgg gccaggttga cacctgcgga
     1621 caaggcagca ataaggaaag aactaaatga atttaaaagc acggaaatgg aagttcacga
     1681 agagagtcga cagtttacaa ggtttcaccg tccataatga agcatgggac agcttggaaa
     1741 taaggaccct gacattgcac tgagatttga atgtgt
//
