LOCUS       NM_001109454            8472 bp    mRNA    linear   ROD 23-MAR-2023
DEFINITION  Rattus norvegicus phosphoglucomutase 2-like 1 (Pgm2l1), mRNA.
ACCESSION   NM_001109454 XM_001062178 XM_006229793
VERSION     NM_001109454.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 8472)
  AUTHORS   Maliekal P, Sokolova T, Vertommen D, Veiga-da-Cunha M and Van
            Schaftingen E.
  TITLE     Molecular identification of mammalian phosphopentomutase and
            glucose-1,6-bisphosphate synthase, two members of the
            alpha-D-phosphohexomutase family
  JOURNAL   J Biol Chem 282 (44), 31844-31851 (2007)
   PUBMED   17804405
REFERENCE   2  (bases 1 to 8472)
  AUTHORS   Drago GA, Hopkinson DA, Westwood SA and Whitehouse DB.
  TITLE     Antigenic analysis of the major human phosphoglucomutase isozymes:
            PGM1, PGM2, PGM3 and PGM4
  JOURNAL   Ann Hum Genet 55 (4), 263-271 (1991)
   PUBMED   1840235
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JACYVU010000042.1.
            
            [WARNING] On Apr 3, 2024 this sequence was replaced by
            NM_001109454.4.
            
            On or before Jul 22, 2021 this sequence version replaced
            XM_006229793.3, NM_001109454.2.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMD00132261,
                              SAMD00132262 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            inferred exon combination :: based on alignments, homology
            RefSeq Select criteria    :: based on conservation, expression,
                                         longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-399               JACYVU010000042.1  5034441-5034839
            400-567             JACYVU010000042.1  5057918-5058085
            568-674             JACYVU010000042.1  5059923-5060029
            675-759             JACYVU010000042.1  5060983-5061067
            760-843             JACYVU010000042.1  5063054-5063137
            844-1037            JACYVU010000042.1  5066229-5066422
            1038-1227           JACYVU010000042.1  5068038-5068227
            1228-1325           JACYVU010000042.1  5068526-5068623
            1326-1503           JACYVU010000042.1  5069241-5069418
            1504-1597           JACYVU010000042.1  5071808-5071901
            1598-1727           JACYVU010000042.1  5072561-5072690
            1728-1917           JACYVU010000042.1  5073141-5073330
            1918-2051           JACYVU010000042.1  5075041-5075174
            2052-8472           JACYVU010000042.1  5077134-5083554
FEATURES             Location/Qualifiers
     source          1..8472
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q32"
     gene            1..8472
                     /gene="Pgm2l1"
                     /note="phosphoglucomutase 2-like 1"
                     /db_xref="GeneID:685076"
                     /db_xref="RGD:1583226"
     exon            1..399
                     /gene="Pgm2l1"
                     /inference="alignment:Splign:2.1.0"
     CDS             289..2154
                     /gene="Pgm2l1"
                     /EC_number="2.7.1.106"
                     /codon_start=1
                     /product="glucose 1,6-bisphosphate synthase"
                     /protein_id="NP_001102924.1"
                     /db_xref="GeneID:685076"
                     /db_xref="RGD:1583226"
                     /translation="MAENANDDLNSNLLHAPYLTGDPQLDTAIGQWLRWDKNPKTKEQ
                     IENLLRNGMNKELRDRLCCRMTFGTAGLRSAMGAGFCYINDLTVIQSTQGMYKYLERC
                     FSDFKQRGFVVGYDTRGQVTSSCSSQRLAKLTAAVLLAKDVPVYLFSRYVPTPFVPYA
                     VQELKAVAGVMITASHNRKEDNGYKVYWETGAQITSPHDKEILKCIEECVEPWDDSWN
                     DNLVDTSPLKKDPLQDICRRYMEDLKKICFYRDLNSKTTLKFVHTSFHGVGHDYVQLA
                     FQVFGFKPPIPVPEQKDPDPDFSTVKCPNPEEGESVLELSLRLAEKENARIVLATDPD
                     ADRLAVAELQENGHWKVFTGNELAALFGWWMFDCWKKSKPNADVKNVYMLATTVSSKI
                     LKAIALKEGFHFEETLPGFKWIGSRIKDLLGHGKEVLFAFEESIGFLCGTSVLDKDGV
                     SAAVVVAEMAAFLDARKVTLMEQLMKVYETYGYHMSKTSYFLCYDPPTIKTIFERIRN
                     FESPKEYPKFCGAFAILHVRDITTGYDSSQPNKKSVLPVSKNSQMITFTFQNGCVATL
                     RTSGTEPKIKYYAEMCASPGQSDTALLEEELKKLIDALIENFLEPSKNGLIWRSV"
     exon            400..567
                     /gene="Pgm2l1"
                     /inference="alignment:Splign:2.1.0"
     exon            568..674
                     /gene="Pgm2l1"
                     /inference="alignment:Splign:2.1.0"
     exon            675..759
                     /gene="Pgm2l1"
                     /inference="alignment:Splign:2.1.0"
     exon            760..843
                     /gene="Pgm2l1"
                     /inference="alignment:Splign:2.1.0"
     exon            844..1037
                     /gene="Pgm2l1"
                     /inference="alignment:Splign:2.1.0"
     exon            1038..1227
                     /gene="Pgm2l1"
                     /inference="alignment:Splign:2.1.0"
     exon            1228..1325
                     /gene="Pgm2l1"
                     /inference="alignment:Splign:2.1.0"
     exon            1326..1503
                     /gene="Pgm2l1"
                     /inference="alignment:Splign:2.1.0"
     exon            1504..1597
                     /gene="Pgm2l1"
                     /inference="alignment:Splign:2.1.0"
     exon            1598..1727
                     /gene="Pgm2l1"
                     /inference="alignment:Splign:2.1.0"
     exon            1728..1917
                     /gene="Pgm2l1"
                     /inference="alignment:Splign:2.1.0"
     exon            1918..2051
                     /gene="Pgm2l1"
                     /inference="alignment:Splign:2.1.0"
     exon            2052..8472
                     /gene="Pgm2l1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gggcgaaggc ggcgacccag acatctggga ctgttgttgt tctctcgcct cacgcccgcc
       61 tcagtcagtt cgagctgaga tccggagcta gtctgctggg aggcggctgt cctgtctccg
      121 ccctccctcc gggttcgctg aagctgcggc aggagccggc gctgactgaa cagctcgcgg
      181 ttggtctctc atgcccttcg tcaaggaggg ggtttctgga ccctggtgag cgcacctaga
      241 gcccccagat tcggtatctt cgtctgcccc tcgggaccgc agctcatcat ggctgagaac
      301 gcaaatgatg acctgaactc taacctgctc cacgccccct acctcaccgg ggacccccag
      361 ctagacacgg ccatcgggca gtggctgcgt tgggacaaga atcccaaaac aaaagagcag
      421 attgaaaatc tcttgcggaa tgggatgaac aaggaattgc gtgatcgtct ttgttgccgg
      481 atgacttttg ggactgcagg acttcgatct gccatgggag cagggttctg ctacattaat
      541 gaccttacag taatacagtc aacacaaggg atgtacaaat acctggagag gtgtttttca
      601 gacttcaagc agagaggctt tgttgttggc tatgacaccc ggggtcaagt gactagcagc
      661 tgcagcagcc agaggcttgc taaactcact gctgcggtgt tgctggctaa agatgttcct
      721 gtttaccttt tttcaagata cgttcctaca cctttcgtac catatgcagt tcaggagctc
      781 aaagcagtcg caggtgtgat gattactgct tctcataacc gcaaagagga caacgggtac
      841 aaggtttatt gggaaactgg tgctcaaatc acatctccac atgataagga aatcctgaaa
      901 tgtatagagg agtgtgtgga gccctgggat gactcttgga atgataattt agtggacacc
      961 agcccactga agaaagatcc tcttcaggac atttgcagga gatacatgga agacctgaaa
     1021 aagatctgtt tttacaggga cttaaattca aagaccacct tgaagtttgt acatacctcc
     1081 tttcatggcg ttggacatga ctacgtgcag ttggcttttc aagtatttgg ttttaagcct
     1141 ccaattccag tcccagaaca gaaagatcca gatccagact tttctactgt taaatgtcca
     1201 aaccctgaag aaggagaatc tgtgctggaa ctgtccctga gactggcaga gaaagaaaat
     1261 gcacggatag tgctagccac agatcctgat gcagaccggc tggcagtagc agaacttcag
     1321 gagaatggtc attggaaggt gttcacaggg aatgagttgg cggctctgtt tgggtggtgg
     1381 atgtttgatt gctggaagaa aagtaaacca aatgccgacg tgaagaatgt ttacatgcta
     1441 gccaccactg tctcttctaa aattttaaag gcaattgccc ttaaagaagg atttcatttt
     1501 gaagaaacat tgccaggctt taaatggatt ggaagtagga taaaagatct cctaggacat
     1561 ggaaaagaag tcctttttgc atttgaagag tctattggct ttctgtgtgg aacctctgtg
     1621 ctggacaaag atggagtcag tgcagctgtt gttgttgctg aaatggccgc tttcctggat
     1681 gccaggaagg taacactgat ggagcaactg atgaaagttt acgaaacata cggttatcac
     1741 atgtcaaaaa cttcatattt cttgtgttat gacccaccta ccatcaaaac catctttgaa
     1801 aggattcgca attttgagtc tccaaaggaa tatccaaagt tctgtggggc atttgctatt
     1861 ttgcatgtac gggacataac cactggctat gatagcagcc agccaaataa gaaatcagta
     1921 ctgcctgtga gcaaaaacag ccaaatgatc acatttactt ttcaaaatgg ctgtgttgct
     1981 actcttcgaa caagtgggac agaaccaaag ataaagtatt atgcagagat gtgcgcatca
     2041 cctggccaga gtgacactgc cttactggaa gaagaattaa agaaactcat tgatgctctg
     2101 atagagaatt ttcttgaacc cagtaagaat ggactgatct ggcgttctgt gtagggcaca
     2161 tcagtacgtt atgcctttgc actgacatat ggaacgaaac ctccaagaac tccactcagt
     2221 gaaccttgtg ttagaattct ctcgtctgcc aagttatctt tccccttttc tttcctgtgt
     2281 tcagccggct aaatagatta tatacatttg aaatgaaaat gtttggatat gagtcaaata
     2341 tttccaaaat cttaagtgac agtcattaca atgaaagtgt ttcagtggct cgctgttcct
     2401 cctgtatcac aaacaataca aaagtgagtt ttcttattga actgtggtta agcttagtta
     2461 tatatcttgt aattgtgtac agcatggttg aaagaagtca aacattacat aactataggg
     2521 ttagttagga cattctttct taatggtgtg tgtgtgtgtg gaagtattgt cttgcccagg
     2581 gtgggaaagt tctgttgtag atattgtttt tcaaattaga aacctagctt ggtgacatat
     2641 tcctgttaca gccttagggg gctgaggcag gaggatcatt agtttatggc cagcctgttg
     2701 cacaataatg ttctgtctcc acaaaaaaat aaaaaagaaa gaaaagaaaa aaaactgtat
     2761 ctaggtcatt taggttttct gactaggaca gatgttgcag tctgtggttg tgcacccgtg
     2821 atggatgtgt ccttggcgtg gtgatcattt acgtatgtat ttaagacgaa cgtttactga
     2881 acacaaaaca gtagtagcag cactccgagt ggatttactc ttgtcaaatt cctcagtgca
     2941 ttctcagggt caggtgtgaa ccgaaacgac gtggaacgta attccatcag tccattttca
     3001 ggtagttaag gaagatcttc cagactgtat aggcgcttcc tctacagaaa acagatctgt
     3061 tgacatctag agatgggtgt agaaaaaggt cttaatgtgg cctaatgtga ctgcagctgg
     3121 gtcttcatgc taggacttag ttatcatagc ctgtaagtga caagctccgt cctgtggcac
     3181 aagcatggca tttattcggc agtctttttg aattacattt tcatagccag gtttgttgta
     3241 tctgataagg tgatgctaat ttcaataaga aatgaagcat caggttagaa gtatttccta
     3301 cagccataca accttgattc aatacccagt ctcacttcat ctcagaagcc aagcaaggct
     3361 aaggtgctcg gatgggaaat cttagtatga agcactgaaa ctgatgttca aaactgaggt
     3421 cagtctattt tagggtgttg ctggctttgg aatttctgat catataaata cttttcatct
     3481 ttttcagtgc aaaacagttt tcaggaaagt cacttgaggt tgactcttca gccttctgac
     3541 gccctaatag aaaaatagtg tctaagcttt ccacattata tccctacaca gtttacagaa
     3601 tacatacatg atagtcatga tgacagtagc aaggctttca ggtgtaatca tttaagaaaa
     3661 tttgcctata ggagacagca ctgatgttag atgatttgtt tcctaaaaat aaatactaaa
     3721 aagcctgaac caattagaac gttcattaga ccatggtttg gtttgttgca gcttgaggat
     3781 aactgtgtgg ggataatccc aacactgctt ttacactgcg ttgccacgac tgctctgtgt
     3841 tccttcctta gagctgggtc ctgtatggct atggatgaca gctagtgact gttcagtgcc
     3901 actttaaaat aatctcactc tatgagatta ttttaaagac tttgtgctaa agaagtagtg
     3961 catagaattt ttttgtttta ttttttaaaa tgtcagcttt taggagtatg aacagtaatt
     4021 taggaaatag catgtattct acaaagtggc ataatcaaag ctgtacattg gaaaacatgc
     4081 atattcagtt ttagtgtctg tgtctcagtg gcccaaggac aaaatgaaac ttaagtgatg
     4141 tgacagccaa cttataacaa aagagccaca tcatgattgc ccttcactta caagaacatt
     4201 tttgtttcca tgcttaagca tatttaagaa ataagtcatc ttaaagtgaa gttactgaca
     4261 atcgagctct tatcttgaaa agctaaattc caactctata taaaggttcc gagagtgcat
     4321 aagttgagga aactatttga ttttgtctac agaaatcaga atcagaatcc atctgagcat
     4381 gtttaacatg aacttgacac aatgggtgca taggtgctta acaggataaa tttaacaaca
     4441 gctcaagaga ggagtgccag cctgtgcgtc tcagccttgg gctaaactac gttgtttatc
     4501 tcttcccctt ttttggcaat aatatgggaa tatatgctct ttgagcaaat aaatcaaaac
     4561 aggtattttc tgaggaaaag aattagactg gaacatagcc cagtggtaaa gcacttacct
     4621 agcatgcaga taaagcaaag cttacatttg atcactggcg atacaaaaaa agaaagagaa
     4681 agaaggttat tattgatgga gcaaagtcaa atcataaagt ggcaataacc aataagagac
     4741 caacaaacta tatatacatg ccagtaatgg tgacagaaga aaagcttgag aagtacaaac
     4801 catgcactgt aacaggataa actgtatgtg aggctgttca cttatgtttg tgaggacgca
     4861 cagacagcaa gcctatactg ttttcattcc ttcagtagtg atcgctgaaa agaagcccag
     4921 ttctaggagg tgaggttcag ttgagctgtg gggtgttatt ttagagtcac tcgaagataa
     4981 agaacaaaat taaaagaaat aaaaccaaga ttgaaaagta tagcctctaa gaaaaagttc
     5041 aaagaattaa gatttttgga ctctgaaaca aagagctatt gagttcattt accaaaccat
     5101 aagttattca ttgggatgtt tactaaaggt atcaaagtaa gagggactaa tggcaccctg
     5161 attatctctg gtaaagacac catggggaat aaagttgtaa aaaaacaaga cctgttctat
     5221 aaacacggaa aaaaaagata tagaagggag ctagttgaaa agtgagtcaa acgggtagga
     5281 gaagtttaag agaaggataa tggggttact gtgatcataa tgcattctgt acatgtacgt
     5341 aatggtcaga aataaatgaa tagacaacgt gaaatgttta agaggttaga atttcttggg
     5401 cagaagtgat tataaaacct atttgaaacc ttatttttga tgggataata tttgaaatat
     5461 taagggagat accagatggc agtttaaaga tccttcaagc acatttttaa gaatcgggtt
     5521 gggacaagac ttatgtatag agcactatca gtaacttctg catttcactc cgtatctggt
     5581 tggctcacca gtaacttgta tatattttga atgggaggtg catgggtgca gtgatgggtg
     5641 ttctctttaa tttgcaagct gtatgagact tgaatgcact cttgttcatc tcggggaatg
     5701 agcagcttta taagatattt aagatttatt gcaaatataa agtatcagta tttggatata
     5761 gtaacttaaa gagagattct aagagattgg atattttgtg atgtctgcat gtagcaagta
     5821 gacacccccc ccccccgcca tttcctcatc aagatgcttc tgaaattgat gcaacagaga
     5881 gtgggagtcc cctggaaggg ttgagtactg ctgttcctgc tgctgttctc ggacctccca
     5941 ctgatatttc taaagcctga aaactacaaa ttccacttgg aaacatttaa tttcccacct
     6001 ttcctgctct acctctcttc cctaggcatc ctctctctta ctgtgaaatg ctactaccct
     6061 gttacctcac tgataagtct taactgtgtt cattcagatg gctttaaact tagtcgtgaa
     6121 ttgtttatag actgttgttt tcattgttgt tgtctgaata tctgagatgt actgtatgaa
     6181 gtaacctcac tatctttcaa agcccatttc tggttgctgg acactcctag atggcgtcac
     6241 tgtgggcttt acaatgaatt tgttttctga atttgttcta gaaactgatg aggaaacaac
     6301 tataccaacc aaagtagtag gttgaccaag gattttattg ggggtcctct gtgctttggg
     6361 cagtaagagt acaaaaattt gagggaattt tttttttaca ttgcccctca acgcatttta
     6421 ccataagccg aaagaagtcg aagagagctg gttgtggtaa ctcatatgta taatctcagc
     6481 cctggagaaa ctgaggcagg agaattgctg ggagttcaca gtcagcttag gctacatgga
     6541 gagatctaga cagaaaaacc ttaaaataga agagaacagt gcattgtctg cctcttcaca
     6601 aagcattggt ttagtgccag tcaaacacaa gtcagtgtta ctaatatttt taactagaga
     6661 gagagagaga gagggagaga gagagagaga gagagagaga gagagagaga gagagaggga
     6721 gagagagata acctatgcat ttaattaaga ggccaagaca aggacgaagt gaccagagtc
     6781 tgctttctaa attttccatc cacagaaccc taaagtagaa aagtgtgaaa aggatggaaa
     6841 tggggcccag agcaaagccc aaagaagcca cacactggcg tgaggccatg agagcctctc
     6901 agtcacagtg gattctcaat agagtaaact ctaagagaaa catggagcca ggacggagct
     6961 cagtggtaga gtgcttgcct gacatgccaa aggtcctagg tccaacatcc ccagcaccat
     7021 tgaaaacatt taaaaagggg aaaataccag aaaagaacac aagcctgtca tgtaattcct
     7081 caactcccag ccccagaccc ccacctgcag tggctgcttt ttcctgaagg aatacacaat
     7141 gaccttataa gaaatgtgca ttctaggcta ttctctgcct ttctgacctg tacttccaaa
     7201 ctgttaatgc cagaccaatt ggcctgcaat atgttaccct tgaaccttat aacattgtct
     7261 gatctataag ccaatttgtt ttctttaatt cactgacaga cactcttcaa cccacctgtc
     7321 agctgcctga catggttcat tgtttttaat atctgttttt cttaattcag tatctcctgt
     7381 catgcagtat ttaactggtg ataatagtag taaaggaaca agcttaaaag ataataaaac
     7441 agtagttttc caattcagtt tctaaaacag tattactgag atatccagta agcaacattt
     7501 actaagcatg cataccgtta aatacttgtt gtcttaggga ttctgttgct gtgataaaca
     7561 ccatgaccaa aaaaagcaac tggggaaagg aggggtttat ttcctccttg agcttatact
     7621 ccatccctgg gggaagctag ggcaggaact cagggcacga acctggaggc tggaactgaa
     7681 gcagaggcca tggaggggtg ctgcttcatg gcttgcctgc tttttgagaa cacctaggtc
     7741 cacaatcccg gggcgagggg gggggggggg ggcaccacac acagtgaaac ggcccctccc
     7801 acctctatta tcaagaaaat gccccataag ccaatcggat ctgggcattt tcccaactga
     7861 ggtttcctca tctaaaagaa ctagcttttg tgtcaagttg acataaacct atgcagcaca
     7921 ctgtttcttt gaagagtaca aagcatcttt caacatgaaa gtatatataa ttttgctcgc
     7981 aaaacaaggt tttggccagg aaggctacga atgtatctta tatgggttta atgtcactgg
     8041 tctggatgcc attttgaacc taatagctcc acctttcaag tgagtcacat ctgatttaat
     8101 aatgcttaat gcattttgtc caatattagg attcatcatg tgtgttattg gagtcactca
     8161 ggcacaaaaa aatgggggga ggggtgtctg tacctgtgta tgatgagacc atgttataga
     8221 ccactataag ctcttggtgt acattattga atatgacagg taaaacacag aattaagaat
     8281 gtaatacttt tctagtagta gctcagaatt gtgcccttgt tttcaacagt ttctgtcaat
     8341 atctcatctt tccctgtaaa agaacagggt ctattgttag cctgtgagaa tttgcacttt
     8401 atgtatttgt gtgtggattt ctgtggtttt aaccaaatga aatgttctca gtaataaaca
     8461 ggtctctcca ta
//
