LOCUS       NM_001191961            1326 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus peptidoglycan recognition protein 3 (Pglyrp3),
            mRNA.
ACCESSION   NM_001191961 XM_017591040 XM_574982
VERSION     NM_001191961.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1326)
  AUTHORS   Saha,S., Jing,X., Park,S.Y., Wang,S., Li,X., Gupta,D. and
            Dziarski,R.
  TITLE     Peptidoglycan recognition proteins protect mice from experimental
            colitis by promoting normal gut flora and preventing induction of
            interferon-gamma
  JOURNAL   Cell Host Microbe 8 (2), 147-162 (2010)
   PUBMED   20709292
REFERENCE   2  (bases 1 to 1326)
  AUTHORS   Cho,S., Wang,Q., Swaminathan,C.P., Hesek,D., Lee,M., Boons,G.J.,
            Mobashery,S. and Mariuzza,R.A.
  TITLE     Structural insights into the bactericidal mechanism of human
            peptidoglycan recognition proteins
  JOURNAL   Proc Natl Acad Sci U S A 104 (21), 8761-8766 (2007)
   PUBMED   17502600
REFERENCE   3  (bases 1 to 1326)
  AUTHORS   Lu,X., Wang,M., Qi,J., Wang,H., Li,X., Gupta,D. and Dziarski,R.
  TITLE     Peptidoglycan recognition proteins are a new class of human
            bactericidal proteins
  JOURNAL   J Biol Chem 281 (9), 5895-5907 (2006)
   PUBMED   16354652
REFERENCE   4  (bases 1 to 1326)
  AUTHORS   Dziarski,R. and Gupta,D.
  TITLE     The peptidoglycan recognition proteins (PGRPs)
  JOURNAL   Genome Biol 7 (8), 232 (2006)
   PUBMED   16930467
  REMARK    Review article
REFERENCE   5  (bases 1 to 1326)
  AUTHORS   Liu,C., Xu,Z., Gupta,D. and Dziarski,R.
  TITLE     Peptidoglycan recognition proteins: a novel family of four human
            innate immunity pattern recognition molecules
  JOURNAL   J Biol Chem 276 (37), 34686-34694 (2001)
   PUBMED   11461926
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000002.1.
            
            On or before May 21, 2021 this sequence version replaced
            XM_017591040.2, NM_001191961.1.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMN06680416,
                              SAMN06680421 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-204               JAXUCZ010000002.1  180174931-180175134
            205-406             JAXUCZ010000002.1  180176970-180177171
            407-525             JAXUCZ010000002.1  180179282-180179400
            526-678             JAXUCZ010000002.1  180180045-180180197
            679-877             JAXUCZ010000002.1  180181427-180181625
            878-996             JAXUCZ010000002.1  180183857-180183975
            997-1197            JAXUCZ010000002.1  180184636-180184836
            1198-1326           JAXUCZ010000002.1  180185879-180186007
FEATURES             Location/Qualifiers
     source          1..1326
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="2"
                     /map="2q34"
     gene            1..1326
                     /gene="Pglyrp3"
                     /gene_synonym="Pglyrp3b"
                     /note="peptidoglycan recognition protein 3"
                     /db_xref="GeneID:499658"
                     /db_xref="RGD:1593164"
     exon            1..204
                     /gene="Pglyrp3"
                     /gene_synonym="Pglyrp3b"
                     /inference="alignment:Splign:2.1.0"
     CDS             156..1175
                     /gene="Pglyrp3"
                     /gene_synonym="Pglyrp3b"
                     /note="peptidoglycan recognition protein 3b"
                     /codon_start=1
                     /product="peptidoglycan recognition protein 3 precursor"
                     /protein_id="NP_001178890.1"
                     /db_xref="GeneID:499658"
                     /db_xref="RGD:1593164"
                     /translation="MLCRLLAFSALSLVACGSPTIVSRKVWGASSLTCRVPLSLPVPY
                     LIIEQVTRMQCQDQTSCSQVLRVLHSHYVHNKGWCDVAFNFLVGNDGKVYEGVGWHVQ
                     GLHTQGYNNVSLGIAFFGSKIGSSPSPAALSATEDLIFFAILNGYLSPKYIQPFLLKE
                     ETCLVPQHSEIPKKACPNIIPRTAWEARETHCSQMNLPAKFVIIIHTAGESCNESADC
                     LIRVRDTQSFHMDKQDFCDIAYHFLVGQDGVVYEGVGWTIEGSHTYGYNDIALGIAFM
                     GNFVEKPPNEASLEAAQSLIQCAVAMGYLASNYLLMGHSDVSNILSPGQALYNIIKTW
                     PHFKH"
     exon            205..406
                     /gene="Pglyrp3"
                     /gene_synonym="Pglyrp3b"
                     /inference="alignment:Splign:2.1.0"
     exon            407..525
                     /gene="Pglyrp3"
                     /gene_synonym="Pglyrp3b"
                     /inference="alignment:Splign:2.1.0"
     exon            526..678
                     /gene="Pglyrp3"
                     /gene_synonym="Pglyrp3b"
                     /inference="alignment:Splign:2.1.0"
     exon            679..877
                     /gene="Pglyrp3"
                     /gene_synonym="Pglyrp3b"
                     /inference="alignment:Splign:2.1.0"
     exon            878..996
                     /gene="Pglyrp3"
                     /gene_synonym="Pglyrp3b"
                     /inference="alignment:Splign:2.1.0"
     exon            997..1197
                     /gene="Pglyrp3"
                     /gene_synonym="Pglyrp3b"
                     /inference="alignment:Splign:2.1.0"
     exon            1198..1326
                     /gene="Pglyrp3"
                     /gene_synonym="Pglyrp3b"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 catgtgctgg tcctcagaag tgaaccaggc aatagagaaa caaacagggt gctatgcagt
       61 tagcatagtc attttaactg tcagtgttct ccaaggccag ctccctccag gactgactac
      121 cagactccac gctggtgtcc tgggaccatt tgaagatgct gtgcaggctt cttgccttct
      181 ctgctctgag tcttgtggcc tgtggcagtc ctaccatagt ttcccgaaaa gtgtggggag
      241 caagttcact cacctgcaga gtcccactga gcctgcctgt gccctacctc atcatagagc
      301 aggttaccag gatgcaatgc caagatcaga cctcgtgcag ccaggttttg cgggttctac
      361 actcccatta tgtccacaac aaaggctggt gtgatgtggc tttcaacttc ctggttggga
      421 atgatggcaa ggtgtatgaa ggtgtcggtt ggcatgtcca aggtttgcac actcaaggct
      481 acaataatgt ttccctgggc attgccttct ttggcagtaa gataggaagc agccccagtc
      541 ctgctgctct atcagctaca gaggacctga tcttctttgc catcctgaat ggctacctgt
      601 cacccaagta cattcagcca tttcttttaa aagaagaaac ctgtttggtt cctcaacact
      661 cagagatacc caaaaaagca tgccccaata tcataccacg gactgcttgg gaagccagag
      721 agacacattg ctctcagatg aaccttccag ccaaatttgt catcatcatc cacactgctg
      781 gagaaagctg caatgaatct gcagactgct tgattcgtgt gagagacaca cagtcctttc
      841 acatggacaa acaagatttc tgtgacattg catatcactt cctagtgggt caagatggtg
      901 tagtatatga aggagttggc tggactattg aaggctctca cacctatgga tacaatgata
      961 ttgctcttgg aattgccttt atgggaaact ttgtagaaaa gcctccaaat gaagcttcac
     1021 tggaggcagc ccagagcctg atccagtgtg ctgtggccat ggggtacctg gcctccaact
     1081 acctgctaat gggccacagt gatgtgtcca acatcctgtc ccctggacaa gcactataca
     1141 acatcatcaa gacatggcct cacttcaagc actgaaaaag accccagtgc catctaagat
     1201 gatacagcaa gaaggccttg gcctgatgat gaccttgaac ttcccagagt tcagactaca
     1261 gaaaataaat ctttgttcac tatgaataac ccagtctcaa gtatctgtta atgtctcaaa
     1321 tattct
//
