LOCUS       NM_001106066            2376 bp    mRNA    linear   ROD 01-JUN-2024
DEFINITION  Rattus norvegicus 6-phosphogluconolactonase (Pgls), mRNA.
ACCESSION   NM_001106066 XM_001069380 XM_214296
VERSION     NM_001106066.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2376)
  AUTHORS   Gonzales,P.A., Pisitkun,T., Hoffert,J.D., Tchapyjnikov,D.,
            Star,R.A., Kleta,R., Wang,N.S. and Knepper,M.A.
  TITLE     Large-scale proteomics and phosphoproteomics of urinary exosomes
  JOURNAL   J Am Soc Nephrol 20 (2), 363-379 (2009)
   PUBMED   19056867
REFERENCE   2  (bases 1 to 2376)
  AUTHORS   Collard,F., Collet,J.F., Gerin,I., Veiga-da-Cunha,M. and Van
            Schaftingen,E.
  TITLE     Identification of the cDNA encoding human
            6-phosphogluconolactonase, the enzyme catalyzing the second step of
            the pentose phosphate pathway(1)
  JOURNAL   FEBS Lett 459 (2), 223-226 (1999)
   PUBMED   10518023
REFERENCE   3  (bases 1 to 2376)
  AUTHORS   Schofield,P.J. and Sols,A.
  TITLE     Rat liver 6-phosphogluconolactonase: a low Km enzyme
  JOURNAL   Biochem Biophys Res Commun 71 (4), 1313-1318 (1976)
   PUBMED   971315
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH474031.2.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_214296.4, XM_001069380.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: FQ233522.1, AW141722.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132262
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..2376
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="16"
                     /map="16p14"
     gene            1..2376
                     /gene="Pgls"
                     /note="6-phosphogluconolactonase"
                     /db_xref="GeneID:290636"
                     /db_xref="RGD:1307001"
     exon            1..1800
                     /gene="Pgls"
                     /inference="alignment:Splign:2.1.0"
     CDS             1411..2286
                     /gene="Pgls"
                     /EC_number="3.1.1.31"
                     /note="6PGL"
                     /codon_start=1
                     /product="6-phosphogluconolactonase"
                     /protein_id="NP_001099536.1"
                     /db_xref="GeneID:290636"
                     /db_xref="RGD:1307001"
                     /translation="MALAQSARTHGSSAVAQAHWRTGLCPERCRLPAAMAAPAPGLIS
                     VFSSPQELGASLAQLVAQRAASCLEGNRGRFALGLSGGSLVSMLARDLPAATAPAGPA
                     SFARWTLGFCDERLVPFDHAESTYGLYRTHLLSKLPIPDSQVLTIDPALPVEDAAEDY
                     ARKLRQAFQGDTVPVFDLLILGVGPDGHTCSLFPGHPLLQEREKIVAPIGDSPKPPPQ
                     RVTLTLPVLNAAQSVIFVATGEGKAAVLKRILEDQESALPAAMVQPRTGALCWFLDEA
                     AARLLSVPFEKHSTL"
     exon            1801..1908
                     /gene="Pgls"
                     /inference="alignment:Splign:2.1.0"
     exon            1909..2010
                     /gene="Pgls"
                     /inference="alignment:Splign:2.1.0"
     exon            2011..2151
                     /gene="Pgls"
                     /inference="alignment:Splign:2.1.0"
     exon            2152..2376
                     /gene="Pgls"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ggcctgaatg ggggcacaag cctttaatcc cagcatttgg gaagcagaag caggcaggtc
       61 tttgtttgag gccagcctac tctacagagt gacttccaga acaaccaggg ccacaacaac
      121 aacagtcact cttaaacaac aacaaagttc ttgcagtgtt tcacagtgta taacttgcta
      181 cttgaagcca tccatgggca ctcaaggctg taggtttggg attagggtgc agccaatgat
      241 ccagcctgga cttagcattc agcaggccct ggatttagtc ccagcacagt gaccgactgc
      301 attttggagc tctcctgagt tcgggagggt gacacattat cagtcgtctt ttgggtgcaa
      361 tggctcagtg gttaagagta ctcgttgggc ttgcttcctt ccttccttcc atgcaacgat
      421 ctaactcaga cccagggtct cctggactct gcacacactt ggcacagaga tactcatgcg
      481 ggagaaacag ccatgctcat tgaaaaaaaa taaattaagc aaaaataaag gagtaaatta
      541 agagagagga accagagggg gtttatttgg gtcttcatgg tggaagcagc tgtctgtcac
      601 cttctcactg atctacttgg gtcaaggctc ttaacagtcc caaagtttcc gtatgtgggc
      661 cactgggagc cacctgttga agcacatgaa tgggggcagt ttcacaccca aatgcagatg
      721 ttttcaactg ttgggcagca gttgtcccgg ggagtcctct ttctgctgtg ggcagctgtg
      781 agcggaaggc agcggagtgt cactgcatcc gctttcgtaa cacaaaaaaa ggggtgtcgg
      841 ggggttgggg atttggctca gtggtagagt gcttgcctag catgcgcaag gccctgggtt
      901 cggtccccag ctccgaaaaa aaaaaaaaaa ggggtgtcgg gataggcgaa tgtggggagg
      961 gccgtgcagg cacagggaca tcataagtgt gtgtgtatga caagagtccc actgcttagc
     1021 ccaatctggc ctctaactcg ggctagccgc ctgcctttgc cacctgaggg ctagcatgag
     1081 tgtaggtcat cacgcctggc ttattgacct tatcacactg cagctggcgc actctgtgtg
     1141 tccaaccgca ccccggaaac ccgctacacc ctcaagagtg caggtgcatt caggtcacct
     1201 cagccctcaa gtcgaggaag gacgatcagg agcgtgaagc cagccggagc tacatgactc
     1261 cgtcttaaaa aactaaataa aatgcgagaa atcggtccag gaaggcgtcc ccagttcagg
     1321 gaagcactgt ggattgcccg cccaccaccc accccaaaac cctgaggcgc actgtggctt
     1381 cgcttcatct gcgcaactgc acatgcgcct atggccttgg ctcaaagtgc tcggacccat
     1441 ggcagctcgg ccgtcgcgca ggcgcactgg cgtactggcc tctgcccgga gcgctgtcgc
     1501 ctccccgccg ccatggccgc acccgcgccc ggtctcatct cggtcttctc cagcccacag
     1561 gagctgggcg catcgctggc gcagctggtg gcgcagcggg ccgctagctg cttggaaggg
     1621 aaccgtggcc gcttcgctct tggcctgtca ggcggcagcc tggtctccat gctggcccga
     1681 gacctacccg ccgccactgc tcccgcgggg cccgccagct ttgcacgctg gacgctcggc
     1741 ttctgtgacg agcgcctcgt gcccttcgac cacgccgaaa gcacgtacgg cctctaccgg
     1801 acacacctgc tctcaaagct gcccatccca gacagccagg tcctcaccat cgatcccgcc
     1861 ctacctgtgg aggacgctgc agaggactat gccaggaaac tgaggcaggc cttccaagga
     1921 gacactgtcc ctgtgtttga cctgctgatc ctgggagtgg gccctgacgg ccacacctgt
     1981 tcgctcttcc ctgggcatcc cctcctccag gagcgggaga agatcgtggc tcccattggt
     2041 gactccccaa agccaccacc gcagagggtg acccttacac tccctgtgct gaacgcagcc
     2101 caaagtgtca tattcgtggc cacaggggaa ggcaaggcag ctgtgctgaa gcgcatcctg
     2161 gaggaccagg agagcgcgct gcccgccgcc atggtgcagc cgcgcacggg cgccctctgc
     2221 tggttcctgg acgaggcagc tgcacggctg ctgtctgtgc ccttcgagaa gcattccacg
     2281 ttataggggc cgcaccacgc acgctgtggg cacttcgggc cgcagagact acgggagagg
     2341 actacctgca gattaaacag ctttgctgga actctg
//
