LOCUS       NM_001106991            3455 bp    mRNA    linear   ROD 26-FEB-2024
DEFINITION  Rattus norvegicus post-GPI attachment to proteins 6 (Pgap6), mRNA.
ACCESSION   NM_001106991 XM_001061336 XM_220264
VERSION     NM_001106991.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3455)
  AUTHORS   Schroder B, Wrocklage C, Pan C, Jager R, Kosters B, Schafer H,
            Elsasser HP, Mann M and Hasilik A.
  TITLE     Integral and associated lysosomal membrane proteins
  JOURNAL   Traffic 8 (12), 1676-1686 (2007)
   PUBMED   17897319
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473948.1.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_220264.4, XM_001061336.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: CB605612.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132262
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..3455
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="10"
                     /map="10q12"
     gene            1..3455
                     /gene="Pgap6"
                     /gene_synonym="M83; Tmem8; Tmem8a"
                     /note="post-GPI attachment to proteins 6"
                     /db_xref="GeneID:303004"
                     /db_xref="RGD:1311395"
     exon            1..251
                     /gene="Pgap6"
                     /gene_synonym="M83; Tmem8; Tmem8a"
                     /inference="alignment:Splign:2.1.0"
     CDS             134..2452
                     /gene="Pgap6"
                     /gene_synonym="M83; Tmem8; Tmem8a"
                     /EC_number="3.1.1.4"
                     /note="transmembrane protein 8 (five membrane-spanning
                     domains); type I transmembrane protein; transmembrane
                     protein 8A; post-GPI attachment to proteins factor 6;
                     post-glycosylphosphatidylinositol attachment to proteins
                     6"
                     /codon_start=1
                     /product="post-GPI attachment to proteins factor 6
                     precursor"
                     /protein_id="NP_001100461.1"
                     /db_xref="GeneID:303004"
                     /db_xref="RGD:1311395"
                     /translation="MGRVGAGSTARVAAAGSLLLLLLLLARPPPAAARNIKESEAGLV
                     SEHFSQAPQKLSFYSWYGSTRLFHFRVPPDTVLLRWLLHVSQGGPSCADVEITVHFRY
                     GAPPVINPLGTSFPDDTLTHASFHIKTLLSTMLLGNTSVNISHPAPGDWFLVAHLPPS
                     SQKIQVKGFVPTCAYIFQPDMLVMRVVEVSILEPDIPLPQTLLSHPSYLKIFVPEYTQ
                     ELRLELQGCVSSVSPGCPVRLTAGVTTLPRNFQRVLTCTGLAPFCHLLLSSPPWGRWL
                     QVTVESLAEPHVTVGFTAKAAFTACRPWSVTFHHLIQNNPNQTYDTSAVQLSQSAAHW
                     DLGRSGRSSRVDGGPFCLLNYPVLREDTDVVSVHFQPLNGAFVLVHSNMPSVMQLRLD
                     TGMDSGGSFIIVLRANKSEVTNGTSVAACVNVASPFLSFNASLNCTTAFFQGYPMFLS
                     ASSHMANLIIPYPETDNWYLSLQLVCPESPEDCEQAAVRVETVLYLVPCLNDCGPYGQ
                     CLLLRRYGYLYAGCSCKAGWRGWSCTDNSTAQTAAQQRAAALLLTLSNLMFLAPIAIS
                     VHRSFLVEASVYFYTMFFSTFYHACDQPGEAVLCILSYDTLQYCDFLGSGASTWVTIL
                     CMARLKTILKQVLLVLGLLVIAMSLQMDRRGIWNLMGPCVFAFVIMAFMWIYRCGHRR
                     QCYPTSWQRWVFYLLPGISMAFVGIAMYTSMMTSDNYYYTHSIWHILLAGSVAFLLPP
                     REEKAGSWACLQKFPCHYQICRNDRDELYTVT"
     exon            252..426
                     /gene="Pgap6"
                     /gene_synonym="M83; Tmem8; Tmem8a"
                     /inference="alignment:Splign:2.1.0"
     exon            427..634
                     /gene="Pgap6"
                     /gene_synonym="M83; Tmem8; Tmem8a"
                     /inference="alignment:Splign:2.1.0"
     exon            635..762
                     /gene="Pgap6"
                     /gene_synonym="M83; Tmem8; Tmem8a"
                     /inference="alignment:Splign:2.1.0"
     exon            763..1031
                     /gene="Pgap6"
                     /gene_synonym="M83; Tmem8; Tmem8a"
                     /inference="alignment:Splign:2.1.0"
     exon            1032..1360
                     /gene="Pgap6"
                     /gene_synonym="M83; Tmem8; Tmem8a"
                     /inference="alignment:Splign:2.1.0"
     exon            1361..1451
                     /gene="Pgap6"
                     /gene_synonym="M83; Tmem8; Tmem8a"
                     /inference="alignment:Splign:2.1.0"
     exon            1452..1575
                     /gene="Pgap6"
                     /gene_synonym="M83; Tmem8; Tmem8a"
                     /inference="alignment:Splign:2.1.0"
     exon            1576..1712
                     /gene="Pgap6"
                     /gene_synonym="M83; Tmem8; Tmem8a"
                     /inference="alignment:Splign:2.1.0"
     exon            1713..1891
                     /gene="Pgap6"
                     /gene_synonym="M83; Tmem8; Tmem8a"
                     /inference="alignment:Splign:2.1.0"
     exon            1892..2038
                     /gene="Pgap6"
                     /gene_synonym="M83; Tmem8; Tmem8a"
                     /inference="alignment:Splign:2.1.0"
     exon            2039..2155
                     /gene="Pgap6"
                     /gene_synonym="M83; Tmem8; Tmem8a"
                     /inference="alignment:Splign:2.1.0"
     exon            2156..3455
                     /gene="Pgap6"
                     /gene_synonym="M83; Tmem8; Tmem8a"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gcggcaggtc catccgagcc atgggagctc cgggcagagg cagcggcggc ggccgcagag
       61 gcggcagggg ctgcccaggc gggggcgagc ggcgcgggac tcgggagggg tagcacgggc
      121 caagcgtgga gccatgggcc gggttggggc cgggagcaca gcgcgggtgg cagcagccgg
      181 gtcactgctg ctactgctgc tgctcctggc tcggcctccg cctgccgccg cccgcaacat
      241 caaggagagc gaggctggac tggtgtctga gcacttctca caggccccac agaagctgtc
      301 cttctatagc tggtatggta gcacccggct tttccacttc cgtgtgcccc cagacaccgt
      361 gctgcttcga tggctgctgc atgtgtccca gggaggtccg tcatgcgccg acgtagagat
      421 cacagtgcat ttccgctatg gcgcccctcc tgtcatcaac ccgctgggca ccagcttccc
      481 tgacgacacc ttgacccatg cctccttcca tatcaagaca ctgctgagca ccatgttact
      541 gggcaacacc tcagtcaaca tctcccaccc agcccctggg gactggttcc tggtggctca
      601 cctccctccc tcatcccaga agatccaggt gaagggcttt gttccaacct gtgcctacat
      661 cttccagcct gatatgctgg taatgagggt ggttgaagtc tccatcctag agcccgacat
      721 tcccctccca cagacgctgc tctcccaccc cagctacctc aagatctttg tccctgaata
      781 cacccaggag cttcgcttgg aactgcaggg ctgtgtgtcc agtgtgagcc ccggctgccc
      841 agtacgtctc acagcggggg tgaccaccct gcctagaaac ttccagaggg tattgacttg
      901 cactggcctt gctccattct gccatttgct gctgtcctct ccgccctggg gccggtggtt
      961 acaagtgaca gtggagagcc tggctgaacc tcacgtgaca gtgggtttca ctgctaaagc
     1021 tgcctttaca gcgtgtaggc catggagtgt gaccttccat catctaatac aaaacaaccc
     1081 aaaccagact tacgatacct ctgcagtcca gctgtcccaa agtgctgccc actgggacct
     1141 gggcaggagt ggccggagta gcagggtaga cggtggcccc ttctgtctcc tgaactatcc
     1201 agtcctgagg gaggacacag atgtggtgtc tgtacacttc cagcccctga atggggcctt
     1261 cgtgctggtg cattcaaaca tgccttctgt aatgcagctc cgtcttgata caggcatgga
     1321 cagcgggggc tccttcatca ttgtcctgag ggctaacaag tcagaggtca caaatggcac
     1381 ctcggtagca gcttgtgtga atgttgcctc acctttcctc agcttcaacg cttcactcaa
     1441 ctgcaccaca gccttcttcc agggctatcc catgtttctg agtgcctcat ctcacatggc
     1501 caacctcatc atcccctatc cggagacaga caactggtac ctctccttgc agcttgtgtg
     1561 ccctgagagt cctgaggatt gtgaacaggc cgcggttcgc gtggagaccg tcttgtatct
     1621 ggtgccctgt ttgaatgact gtgggcccta tggccagtgt ctcctgctcc gtagatacgg
     1681 ctatctgtac gcaggctgca gctgcaaggc aggttggcgt gggtggagct gcacggacaa
     1741 cagcacagcc cagactgcag cccagcagag ggcagcagca cttctgctca cgcttagcaa
     1801 cctcatgttc ctggccccca ttgctatatc cgtgcaccgc tccttcctgg ttgaggcctc
     1861 tgtctacttt tacactatgt tcttctcaac gttctaccac gcctgtgacc agcctgggga
     1921 ggctgtgttg tgtatcctca gctatgacac gctgcagtac tgcgactttc tgggttctgg
     1981 ggcatccacc tgggtgacca ttctttgcat ggcccgtctg aagacaatcc tgaaacaggt
     2041 actacttgtc ctcggcctac tggtcatcgc tatgtccttg cagatggatc gcaggggcat
     2101 ctggaacctg atgggacctt gtgtctttgc ctttgtgatc atggctttca tgtggatata
     2161 ccgctgtggg caccgacgtc agtgctaccc tacctcgtgg cagcgctggg tcttctacct
     2221 cctgcctggc atctccatgg cttttgtggg catcgccatg tacacttcaa tgatgaccag
     2281 cgacaactac tactacaccc acagcatttg gcacatccta ctggctggca gtgtggcatt
     2341 tcttctccct ccacgagaag aaaaggctgg gtcctgggcc tgtttgcaga agttcccctg
     2401 tcactaccag atctgcagga atgatcggga tgagttgtac acagtgacat gataaggcta
     2461 gctcacggac acccgagact ctaatgacct cttcagccag gacaggaatg agagaggtgc
     2521 ctgtctagcc ccaaccaggt ttccatctga ataaaactgt cctgagaccc ttggcttctt
     2581 tctccagagg agaagaccct ctccacccat aaaatcttta tggccgttgc cagtcagagc
     2641 tgcttccacc tggagataga ccacaggtgc cacgtgtggg cagagcactc tgttatggct
     2701 ggagacacag ataaggggtt cccgtggtcc ccttcctttg ggaagctgtg atgtgagagc
     2761 cacaagcaag gaaggctgag tgcacagaga ccactgtcca tgacatcgtg tacccttgaa
     2821 tgccaccctg ccttggcatg gggatgccct gctgctgcag ttgctatggc agaggccaag
     2881 gtcatcagag agctgattaa gacctggggt gctgtgtgct gtccctccct cattctctgt
     2941 tggagtgggg gatcctggaa agatcctggg gtagcaggct gctcagctgt atgaggtgtg
     3001 gctccagaag gcacacaatg ctatgccagt gtccttctca ccctaagagt cctaggcccc
     3061 agtctggtga gcattctctt gtgctgtcct aggcactagg ttgaggctaa cccctactgg
     3121 atcaatcgag gtttgaggag tgggttctgg agccctggtc cagtctttct ggtttcctgg
     3181 gatcactgag ttggcaatgc agtgtgctct gtctgtatgg ttcccactat gaggcccatc
     3241 tgctctgagt actaggatta caggtgtagg cctctgggct ccttcccaag ctattaacat
     3301 cctttatttg gccaccaaag cacactttag cccctgaaag gggaaacatg tatatattgt
     3361 tggggggagg tggtaaaatg ttactgttct aagatatgaa ggcatatttt tatgtaattg
     3421 gtgaatttaa tattctacaa tgattttttc aaacc
//
