LOCUS       NP_001100461             772 aa            linear   ROD 26-FEB-2024
DEFINITION  post-GPI attachment to proteins factor 6 precursor [Rattus
            norvegicus].
ACCESSION   NP_001100461 XP_001061336 XP_220264
VERSION     NP_001100461.1
DBSOURCE    REFSEQ: accession NM_001106991.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (residues 1 to 772)
  AUTHORS   Schroder B, Wrocklage C, Pan C, Jager R, Kosters B, Schafer H,
            Elsasser HP, Mann M and Hasilik A.
  TITLE     Integral and associated lysosomal membrane proteins
  JOURNAL   Traffic 8 (12), 1676-1686 (2007)
   PUBMED   17897319
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473948.1.
            
            On or before Oct 4, 2007 this sequence version replaced
            XP_220264.1, XP_001061336.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: CB605612.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132262
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..772
                     /organism="Rattus norvegicus"
                     /db_xref="taxon:10116"
                     /chromosome="10"
                     /map="10q12"
     Protein         1..772
                     /product="post-GPI attachment to proteins factor 6
                     precursor"
                     /EC_number="3.1.1.4"
                     /note="transmembrane protein 8 (five membrane-spanning
                     domains); type I transmembrane protein; transmembrane
                     protein 8A; post-GPI attachment to proteins factor 6;
                     post-glycosylphosphatidylinositol attachment to proteins
                     6"
                     /calculated_mol_wt=82461
     sig_peptide     1..33
                     /inference="COORDINATES: ab initio prediction:SignalP:4.0"
                     /calculated_mol_wt=3156
     Region          553..728
                     /region_name="DUF3522"
                     /note="Protein of unknown function (DUF3522); pfam12036"
                     /db_xref="CDD:463441"
     CDS             1..772
                     /gene="Pgap6"
                     /gene_synonym="M83; Tmem8; Tmem8a"
                     /coded_by="NM_001106991.1:134..2452"
                     /db_xref="GeneID:303004"
                     /db_xref="RGD:1311395"
ORIGIN      
        1 mgrvgagsta rvaaagslll lllllarppp aaarnikese aglvsehfsq apqklsfysw
       61 ygstrlfhfr vppdtvllrw llhvsqggps cadveitvhf rygappvinp lgtsfpddtl
      121 thasfhiktl lstmllgnts vnishpapgd wflvahlpps sqkiqvkgfv ptcayifqpd
      181 mlvmrvvevs ilepdiplpq tllshpsylk ifvpeytqel rlelqgcvss vspgcpvrlt
      241 agvttlprnf qrvltctgla pfchlllssp pwgrwlqvtv eslaephvtv gftakaafta
      301 crpwsvtfhh liqnnpnqty dtsavqlsqs aahwdlgrsg rssrvdggpf cllnypvlre
      361 dtdvvsvhfq plngafvlvh snmpsvmqlr ldtgmdsggs fiivlranks evtngtsvaa
      421 cvnvaspfls fnaslnctta ffqgypmfls asshmanlii pypetdnwyl slqlvcpesp
      481 edceqaavrv etvlylvpcl ndcgpygqcl llrrygylya gcsckagwrg wsctdnstaq
      541 taaqqraaal lltlsnlmfl apiaisvhrs flveasvyfy tmffstfyha cdqpgeavlc
      601 ilsydtlqyc dflgsgastw vtilcmarlk tilkqvllvl gllviamslq mdrrgiwnlm
      661 gpcvfafvim afmwiyrcgh rrqcyptswq rwvfyllpgi smafvgiamy tsmmtsdnyy
      721 ythsiwhill agsvafllpp reekagswac lqkfpchyqi crndrdelyt vt
//
