LOCUS       NM_053895               2568 bp    mRNA    linear   ROD 24-JUN-2024
DEFINITION  Rattus norvegicus post-GPI attachment to proteins 2 (Pgap2), mRNA.
ACCESSION   NM_053895 XM_006229838
VERSION     NM_053895.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2568)
  AUTHORS   Hirata,T., Mishra,S.K., Nakamura,S., Saito,K., Motooka,D.,
            Takada,Y., Kanzawa,N., Murakami,Y., Maeda,Y., Fujita,M.,
            Yamaguchi,Y. and Kinoshita,T.
  TITLE     Identification of a Golgi GPI-N-acetylgalactosamine transferase
            with tandem transmembrane regions in the catalytic domain
  JOURNAL   Nat Commun 9 (1), 405 (2018)
   PUBMED   29374258
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2568)
  AUTHORS   Tashima,Y., Taguchi,R., Murata,C., Ashida,H., Kinoshita,T. and
            Maeda,Y.
  TITLE     PGAP2 is essential for correct processing and stable expression of
            GPI-anchored proteins
  JOURNAL   Mol Biol Cell 17 (3), 1410-1420 (2006)
   PUBMED   16407401
  REMARK    GeneRIF: results demonstrate that PGAP2 is involved in the
            processing of GPI-APs required for their stable expression at the
            cell surface
REFERENCE   3  (bases 1 to 2568)
  AUTHORS   Ishii,H., Inageta,T., Mimori,K., Saito,T., Sasaki,H., Isobe,M.,
            Mori,M., Croce,C.M., Huebner,K., Ozawa,K. and Furukawa,Y.
  TITLE     Frag1, a homolog of alternative replication factor C subunits,
            links replication stress surveillance with apoptosis
  JOURNAL   Proc Natl Acad Sci U S A 102 (27), 9655-9660 (2005)
   PUBMED   15983387
REFERENCE   4  (bases 1 to 2568)
  AUTHORS   Lorenzi,M.V., Horii,Y., Yamanaka,R., Sakaguchi,K. and Miki,T.
  TITLE     FRAG1, a gene that potently activates fibroblast growth factor
            receptor by C-terminal fusion through chromosomal rearrangement
  JOURNAL   Proc Natl Acad Sci U S A 93 (17), 8956-8961 (1996)
   PUBMED   8799135
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000001.1.
            
            On or before Feb 7, 2015 this sequence version replaced
            XM_006229838.2, NM_053895.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: U57715.1, SRR26643285.3092.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-223               JAXUCZ010000001.1  166003593-166003815
            224-590             JAXUCZ010000001.1  166015050-166015416
            591-702             JAXUCZ010000001.1  166015635-166015746
            703-877             JAXUCZ010000001.1  166018232-166018406
            878-1130            JAXUCZ010000001.1  166027545-166027797
            1131-1225           JAXUCZ010000001.1  166027901-166027995
            1226-1334           JAXUCZ010000001.1  166028575-166028683
            1335-2568           JAXUCZ010000001.1  166028855-166030088
FEATURES             Location/Qualifiers
     source          1..2568
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q32"
     gene            1..2568
                     /gene="Pgap2"
                     /gene_synonym="Frag1"
                     /note="post-GPI attachment to proteins 2"
                     /db_xref="GeneID:116675"
                     /db_xref="RGD:619744"
     exon            1..223
                     /gene="Pgap2"
                     /gene_synonym="Frag1"
                     /inference="alignment:Splign:2.1.0"
     exon            224..590
                     /gene="Pgap2"
                     /gene_synonym="Frag1"
                     /inference="alignment:Splign:2.1.0"
     exon            591..702
                     /gene="Pgap2"
                     /gene_synonym="Frag1"
                     /inference="alignment:Splign:2.1.0"
     exon            703..877
                     /gene="Pgap2"
                     /gene_synonym="Frag1"
                     /inference="alignment:Splign:2.1.0"
     CDS             713..1465
                     /gene="Pgap2"
                     /gene_synonym="Frag1"
                     /note="FGF receptor-activating protein 1"
                     /codon_start=1
                     /product="post-GPI attachment to proteins factor 2"
                     /protein_id="NP_446347.2"
                     /db_xref="GeneID:116675"
                     /db_xref="RGD:619744"
                     /translation="MYQVPLTLDRDGTLVRLRFTMVALITVCCPLVAFFFCILWSLLF
                     HFKETTSTHCGVPNYLPSVSSAIGGEVPQRYVWRFCIGLHSAPRFLTAFAYWNHYLSC
                     ASPCPGYRLLCRLNFSLNVVENLALLVLTYVSSSEDFTIHENAFIVFIAASLSYMLLT
                     CILWRLTKKHTDRKSYSWKQRLFIINFISFFSALAVYFRHNMYCEAGVYTIFAILEYT
                     VVLTNMAFHMTAWWDFGNKELLITSQPEEKRF"
     exon            878..1130
                     /gene="Pgap2"
                     /gene_synonym="Frag1"
                     /inference="alignment:Splign:2.1.0"
     exon            1131..1225
                     /gene="Pgap2"
                     /gene_synonym="Frag1"
                     /inference="alignment:Splign:2.1.0"
     exon            1226..1334
                     /gene="Pgap2"
                     /gene_synonym="Frag1"
                     /inference="alignment:Splign:2.1.0"
     exon            1335..2568
                     /gene="Pgap2"
                     /gene_synonym="Frag1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ggactatggg gagggacgag gagtcccact ctctctgcgg caacggttgg ctgagaaagg
       61 gtcatgacgt cacacagggc cctcgaagag ggcaggtgag tggctagagt agtgagcacc
      121 aaacagcagt gacgttgggt tcagaccccg cccctttcct tggagcgcgg agactcgcta
      181 cggaagcttc ggccaatcag aaggaagacc caaggatgat atggtgatgg catgcagcca
      241 gaggtaaaat gacaaggtga cttattcgac atgtcaaaat cttgtttcca gagctctctg
      301 actgctctca cgtactcaaa aatagtgggg acagagccga cctggggagg cttggcttca
      361 agagacgcta gattataaag aaagccagga gtcccggtcg ccaaaatggg gaggagccag
      421 tgaagaaacg ggcccagttt cctctttaag acccacccca gagcgctggc cccgcctcac
      481 gccgttgctg ctgcgacccg cccccttcca ctcgcccccg ggctgggctg gggctcccgg
      541 ttccgcgccc ctggctacgg gggtacggcc ccctagccac cactacttgg ggccttctgc
      601 tcaagatccc tccaggcact gcggatggag gcgtggggga gccttggaac ctcagactag
      661 ttttgaatcc ctgccctgcc agtcactagc ttgtggcttt gagtctgaca agatgtacca
      721 ggtcccattg acactggacc gggatgggac cctagtccgg ctccgcttca ctatggtggc
      781 cctgatcacg gtctgctgtc cacttgtcgc cttcttcttc tgcatcctgt ggtccctgct
      841 cttccacttc aaggagacaa catctacaca ctgtggggtg cccaattacc tgccatcagt
      901 gagctctgcc attggtgggg aggttcccca gcgctacgtg tggcgtttct gcattggcct
      961 gcactcggca ccccgcttct tgacagcctt cgcctattgg aaccactacc tcagctgtgc
     1021 atccccgtgc ccgggttacc gccttctctg ccgcctcaac ttcagtctca atgtggtgga
     1081 gaacctggca ctgctcgtgc tcacctatgt ctcctcctcc gaggacttca ccatccatga
     1141 aaatgctttc attgtgttta tcgcggcctc cctcagttac atgctcctca cctgcattct
     1201 ctggcggctg accaagaagc acacagatcg caagtcctac agctggaaac aacggctctt
     1261 catcatcaac ttcatctcct tcttctcggc gctggctgtt tacttccggc acaacatgta
     1321 ttgtgaggct ggagtgtaca ccatctttgc catcctggag tacactgtgg tcctaaccaa
     1381 catggcgttc cacatgacag cctggtggga cttcgggaac aaagagctgc taataacctc
     1441 tcagcctgag gaaaagagat tctaaacccc gtctctgatc ctggaaaaca agaaaccact
     1501 ctggccttcc ctatctcagt gtcctctctg ggcccttctc cgtctgggga ctgggagaga
     1561 agagcaggaa gggtaggaca aggctgaccc cagcactgct gacttctccc cacctctcat
     1621 ctctcatggg gatcttcaag aagcatcact actcactgaa aggtcctaaa aagctgagct
     1681 ggcaggaaag ccctaccact tggtgctaag aaaaaaaaaa aaaaaaaaaa agagagagag
     1741 agaaagaaca aaaaaagaag agtcctgagg ttcatgactg tctagttttt gacctttata
     1801 tagacacgtt tcactaaggt tagggtccag agcaatggct gtgaccgtcc ggtctggtca
     1861 ttgatctgac tgatgtgtct agcgatctac cgtgtacacc cactgtgtgt acacccaggt
     1921 ggtagttcta taacttgccc aggtgttcta gaggtgtaac ctcttcccca tcagcctcac
     1981 tgtgttcccg tgtatgcctg ggggaagtat gttgtgtgat ttctaagggc tttggtctct
     2041 gaggtcatcc aatggaagtg ttgtgttgta cttgacaggt aacttgtccc agaagcagca
     2101 tcaagtgtag gatatatttt cctttcccat ctaaaacctc tggcttcttg gaatatgtct
     2161 gtcatcccaa cacattggag gctgagatgg gtggactgct tcaggatcca cgccaccctg
     2221 ggctacatgt gagaccttgt ctcaaaaatg aaataagatg caaggcacgg tggcacatgc
     2281 ctttaatccc aacacagcag agacaggcaa atatctgttg agttcaaggc cagccagggc
     2341 tatacagtaa gaccctgttt tagaagaaaa aaaaaaaatc aaagaaccct aaaatcgcag
     2401 gcttctgaga cctttccctc cttggatggg gggaggggtc agaggtagat ttccctactc
     2461 cagaatgggt tccttggctt tcctttatcc tcgtgactgt cccacatccc catctttcat
     2521 ttgtatattt tatttcaaag gacaataaat ttttttcttt tgccaaca
//
