LOCUS       NM_053290               1806 bp    mRNA    linear   ROD 17-FEB-2024
DEFINITION  Rattus norvegicus phosphoglycerate mutase 1 (Pgam1), mRNA.
ACCESSION   NM_053290 XM_001053034
VERSION     NM_053290.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1806)
  AUTHORS   Martins-de-Souza,D., Alsaif,M., Ernst,A., Harris,L.W., Aerts,N.,
            Lenaerts,I., Peeters,P.J., Amess,B., Rahmoune,H., Bahn,S. and
            Guest,P.C.
  TITLE     The application of selective reaction monitoring confirms
            dysregulation of glycolysis in a preclinical model of schizophrenia
  JOURNAL   BMC Res Notes 5, 146 (2012)
   PUBMED   22420779
  REMARK    GeneRIF: Data show statistically significant altered levels of Tpi1
            and alteration of Hk1, Aldoc, Pgam1 and Gapdh with borderline
            significance in phencyclidine (PCP) rats compared to controls.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1806)
  AUTHORS   Okuda,H., Tsujimura,A., Irie,S., Yamamoto,K., Fukuhara,S.,
            Matsuoka,Y., Takao,T., Miyagawa,Y., Nonomura,N., Wada,M. and
            Tanaka,H.
  TITLE     A single nucleotide polymorphism within the novel sex-linked
            testis-specific retrotransposed PGAM4 gene influences human male
            fertility
  JOURNAL   PLoS One 7 (5), e35195 (2012)
   PUBMED   22590500
REFERENCE   3  (bases 1 to 1806)
  AUTHORS   Buschow,S.I., van Balkom,B.W., Aalberts,M., Heck,A.J., Wauben,M.
            and Stoorvogel,W.
  TITLE     MHC class II-associated proteins in B-cell exosomes and potential
            functional implications for exosome biogenesis
  JOURNAL   Immunol Cell Biol 88 (8), 851-856 (2010)
   PUBMED   20458337
REFERENCE   4  (bases 1 to 1806)
  AUTHORS   Ghosh,D., Lippert,D., Krokhin,O., Cortens,J.P. and Wilkins,J.A.
  TITLE     Defining the membrane proteome of NK cells
  JOURNAL   J Mass Spectrom 45 (1), 1-25 (2010)
   PUBMED   19946888
REFERENCE   5  (bases 1 to 1806)
  AUTHORS   Jacobowitz,D.M., Jozwik,C., Fukuda,T. and Pollard,H.B.
  TITLE     Immunohistochemical localization of Phosphoglycerate mutase in
            capillary endothelium of the brain and periphery
  JOURNAL   Microvasc Res 76 (2), 89-93 (2008)
   PUBMED   18533197
  REMARK    GeneRIF: The cellular localization of phosphoglycerate mutase
            (PGAM1) type B in the endothelium of the capillaries and arteries
            of the brain, liver and kidneys was determined by
            immunocytochemistry.
REFERENCE   6  (bases 1 to 1806)
  AUTHORS   Urena,J.M., Grana,X., de Lecea,L., Ruiz,P., Castella,J.,
            Carreras,J., Pons,G. and Climent,F.
  TITLE     Isolation and sequencing of a cDNA encoding the B isozyme of rat
            phosphoglycerate mutase
  JOURNAL   Gene 113 (2), 281-282 (1992)
   PUBMED   1533381
REFERENCE   7  (bases 1 to 1806)
  AUTHORS   Egea,G., Urena,J.M., Grana,X., Marsal,J., Carreras,J. and
            Climent,F.
  TITLE     Nuclear location of phosphoglycerate mutase BB isozyme in rat
            tissues
  JOURNAL   Histochemistry 97 (3), 269-275 (1992)
   PUBMED   1314249
REFERENCE   8  (bases 1 to 1806)
  AUTHORS   Uchida,K.
  TITLE     cDNA encoding type B subunit of rat phosphoglycerate mutase: its
            isolation and nucleotide sequence
  JOURNAL   Arch Biochem Biophys 288 (2), 558-561 (1991)
   PUBMED   1832843
REFERENCE   9  (bases 1 to 1806)
  AUTHORS   Fundele,R., Winking,H., Illmensee,K. and Jagerbauer,E.M.
  TITLE     Developmental activation of phosphoglycerate mutase-2 in the testis
            of the mouse
  JOURNAL   Dev Biol 124 (2), 562-566 (1987)
   PUBMED   2824255
REFERENCE   10 (bases 1 to 1806)
  AUTHORS   Omenn,G.S. and Cheung,S.C.
  TITLE     Phosphoglycerate mutase isozyme marker for tissue differentiation
            in man
  JOURNAL   Am J Hum Genet 26 (3), 393-399 (1974)
   PUBMED   4827367
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JACYVU010000054.1.
            
            [WARNING] On Apr 3, 2024 this sequence was replaced by NM_053290.4.
            
            On Feb 10, 2021 this sequence version replaced NM_053290.2.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC065582.1, FQ227359.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132262
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-291               JACYVU010000054.1  1817873-1818163
            292-566             JACYVU010000054.1  1822204-1822478
            567-747             JACYVU010000054.1  1823474-1823654
            748-1806            JACYVU010000054.1  1824426-1825484
FEATURES             Location/Qualifiers
     source          1..1806
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q54"
     gene            1..1806
                     /gene="Pgam1"
                     /gene_synonym="PGAM-B; Pgmut"
                     /note="phosphoglycerate mutase 1"
                     /db_xref="GeneID:24642"
                     /db_xref="RGD:3312"
     exon            1..291
                     /gene="Pgam1"
                     /gene_synonym="PGAM-B; Pgmut"
                     /inference="alignment:Splign:2.1.0"
     CDS             153..917
                     /gene="Pgam1"
                     /gene_synonym="PGAM-B; Pgmut"
                     /EC_number="5.4.2.4"
                     /EC_number="5.4.2.11"
                     /note="BPG-dependent PGAM 1; phosphoglycerate mutase
                     isozyme B; phosphoglycerate mutase 1 (brain)"
                     /codon_start=1
                     /product="phosphoglycerate mutase 1"
                     /protein_id="NP_445742.2"
                     /db_xref="GeneID:24642"
                     /db_xref="RGD:3312"
                     /translation="MAAYKLVLIRHGESAWNLENRFSGWYDADLSPAGHEEAKRGGQA
                     LRDAGYEFDICFTSVQKRAIRTLWTVLDAIDQMWLPVVRTWRLNERHYGGLTGLNKAE
                     TAAKHGEAQVKIWRRSYDVPPPPMEPDHPFYSNISKDRRYADLTEDQLPSCESLKDTI
                     ARALPFWNEEIVPQIKEGKRVLIAAHGNSLRGIVKHLEGLSEEAIMELNLPTGIPIVY
                     ELDKNLKPIKPMQFLGDEETVRKAMEAVAAQGKVKK"
     exon            292..566
                     /gene="Pgam1"
                     /gene_synonym="PGAM-B; Pgmut"
                     /inference="alignment:Splign:2.1.0"
     exon            567..747
                     /gene="Pgam1"
                     /gene_synonym="PGAM-B; Pgmut"
                     /inference="alignment:Splign:2.1.0"
     exon            748..1806
                     /gene="Pgam1"
                     /gene_synonym="PGAM-B; Pgmut"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gtctgtctgg cgagtggaaa gatttcgggg agaaagtgcg cgggagcggg gcgggagagt
       61 gcaagcgcgc aggcgcgacc gggggggggg gggcgggctg cgaggagaat ctcagcgatc
      121 ctcagttact gccgcatcct ctgccggtcg tcatggctgc ctacaagctg gtgctgatcc
      181 ggcatggcga gagcgcctgg aacctggaga accgcttcag cggctggtac gatgccgacc
      241 tgagcccagc gggccacgag gaggcgaagc gcggcgggca ggcgttgcga gatgctggct
      301 atgagtttga catctgcttc acctctgtgc agaagagagc aatccgcacc ctctggacag
      361 tcctggatgc cattgaccag atgtggttgc cagtggtcag gacctggcgt ctcaatgagc
      421 gacactatgg gggtctaaca ggtctcaata aagcagagac tgctgctaag catggtgagg
      481 cacaggtaaa gatctggaga cgatcttacg atgtcccgcc acctccaatg gagcctgatc
      541 atcccttcta cagcaacatc agcaaggacc gcaggtacgc agaccttact gaggaccagc
      601 taccctcctg tgagagcctg aaggatacta ttgccagggc actgcccttc tggaatgaag
      661 aaattgtccc ccagatcaag gaggggaaaa gggtcttgat tgctgcccat ggcaacagcc
      721 tacggggcat tgtcaagcat ctggagggtc tgtcagaaga ggccatcatg gagctgaacc
      781 tgccaactgg catccccatc gtctatgaac tggacaagaa cttgaagccc atcaagccca
      841 tgcagttcct gggagatgag gagaccgtgc gtaaagccat ggaagctgtg gctgctcagg
      901 gcaaggtgaa gaagtgaagg cgaggaggcg gactcctgcc ctgacaccct ctctccctgc
      961 ttgttcctgc ctcctgcacc ctcccctgca cctgccacac tgactacatc tttaggatct
     1021 tcagtttaag ttgtagctgc agatagggac ctgtggctcc cattctcctt ttagtatttt
     1081 atccccggca cccactccct tcatagaatc tagtcagaag aagacctctg gggtgcaggc
     1141 tcttggtcca tatccaggga cggctccctg ttacaggaga gttgagagat agtaattata
     1201 gttttcttag ctctttgttt actaagggtc tgcttaggaa gaaggtcggg agggactgta
     1261 tgtggtatga ccaatgagga gaagctgtgg tccagttttg tccctggaac ctgtcctgca
     1321 ctcttcccac aattaggtaa ctgggggcct agtcattcca gtggagagtg aaagtaacct
     1381 catgccgatt aaaagaccct actttctctc tgaccctaaa ggagctgctg gccctagaag
     1441 gttgggaaca gtcttgtcaa gtctatgtgt tacatttatt tttacaaaaa taaagtatat
     1501 atacatatat cagcacaaaa gcaacgaggt tgctagtggc agttgagagt cctaagtggt
     1561 caccagaaaa aaagccattc ctcatatcaa atgggataaa ctccttgtac ctcttgctgt
     1621 gtttggatcc ctttgccttg ttttgtagag gtgaagcccc ttgatcatgt ccaaggtttt
     1681 gtctttcact gtctgaatca tgttccagct gcttgaccct actgtgtggg ttcagaactc
     1741 gtttgggcat aacaactaag tctctttcca gatcagtata ataaaggagt gatgtgcaat
     1801 acttta
//
