LOCUS       NM_021753               1333 bp    mRNA    linear   ROD 23-JUL-2024
DEFINITION  Rattus norvegicus pepsinogen A3 (Pga3), mRNA.
ACCESSION   NM_021753
VERSION     NM_021753.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1333)
  AUTHORS   Chen,X., Rosenfeld,C.S., Roberts,R.M. and Green,J.A.
  TITLE     An aspartic proteinase expressed in the yolk sac and neonatal
            stomach of the mouse
  JOURNAL   Biol Reprod 65 (4), 1092-1101 (2001)
   PUBMED   11566730
REFERENCE   2  (bases 1 to 1333)
  AUTHORS   Kageyama,T., Ichinose,M., Tsukada-Kato,S., Omata,M., Narita,Y.,
            Moriyama,A. and Yonezawa,S.
  TITLE     Molecular cloning of neonate/infant-specific pepsinogens from rat
            stomach mucosa and their expressional change during development
  JOURNAL   Biochem Biophys Res Commun 267 (3), 806-812 (2000)
   PUBMED   10673373
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AJ251687.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AJ251687.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMD00132261,
                                           SAMD00132263 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1333
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="Sprague-Dawley"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q43"
     gene            1..1333
                     /gene="Pga3"
                     /gene_synonym="Pepf; Pga5"
                     /note="pepsinogen A3"
                     /db_xref="GeneID:60372"
                     /db_xref="RGD:621573"
     exon            1..73
                     /gene="Pga3"
                     /gene_synonym="Pepf; Pga5"
                     /inference="alignment:Splign:2.1.0"
     CDS             21..1184
                     /gene="Pga3"
                     /gene_synonym="Pepf; Pga5"
                     /EC_number="3.4.23.1"
                     /function="unknown"
                     /note="pepsinogen F protein; pepsinogen 5, group I
                     (pepsinogen A); pepsin F-like; pepsinogen A5"
                     /codon_start=1
                     /product="pepsinogen A3 precursor"
                     /protein_id="NP_068521.1"
                     /db_xref="GeneID:60372"
                     /db_xref="RGD:621573"
                     /translation="MKWLWVLGLVALSECLVKIPLMKIKSMRENLRESHMLKDYLEKY
                     PRSRAHVLLEQRRNPSVTYEPMRNYLDLVYIGTISIGTPPQEFKVVLDTGSSDLWVPS
                     IYCSSPACAHHKVFNPLQSSTFLVSGRPVNVAYGSGEMSGFLAYDTVKIGDLTVVAQA
                     FGLSLEEPGRFMEHAVFDGILGLGYPNLGLQGVTPVFDNLWIQGLIPQNLFAFYLSSK
                     DEKGSVLMLGGVDPSYYHGELHWVPVSKPSYWQLAVDSISMNGEIIACDGGCQGIMDT
                     GTSLVTGPRSSILNIQNLIGAKASGDGEYFLKCDTINTLPDIVFTIDSVTYPVPASAY
                     IRKDHSHNCRSNFEESTDDPSDPELWVLGDVFLRLYFTVFDRANNRIGLASAA"
     exon            74..233
                     /gene="Pga3"
                     /gene_synonym="Pepf; Pga5"
                     /inference="alignment:Splign:2.1.0"
     exon            234..351
                     /gene="Pga3"
                     /gene_synonym="Pepf; Pga5"
                     /inference="alignment:Splign:2.1.0"
     exon            352..470
                     /gene="Pga3"
                     /gene_synonym="Pepf; Pga5"
                     /inference="alignment:Splign:2.1.0"
     exon            471..670
                     /gene="Pga3"
                     /gene_synonym="Pepf; Pga5"
                     /inference="alignment:Splign:2.1.0"
     exon            671..787
                     /gene="Pga3"
                     /gene_synonym="Pepf; Pga5"
                     /inference="alignment:Splign:2.1.0"
     exon            788..932
                     /gene="Pga3"
                     /gene_synonym="Pepf; Pga5"
                     /inference="alignment:Splign:2.1.0"
     exon            933..1031
                     /gene="Pga3"
                     /gene_synonym="Pepf; Pga5"
                     /inference="alignment:Splign:2.1.0"
     exon            1032..1333
                     /gene="Pga3"
                     /gene_synonym="Pepf; Pga5"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ccttagcctg ggaaaggatc atgaaatggc tttgggtcct cgggcttgtg gccctctcag
       61 agtgcttggt caaaatccct ctgatgaaga ttaagtccat gcgagaaaac ctgcgggaaa
      121 gccacatgct gaaggattac ctggagaagt accctcgcag ccgtgcccac gtgcttcttg
      181 agcagcgcag gaacccatca gtaacttatg agcctatgag gaactaccta gacctggtct
      241 acatcggcac catcagcatt ggcacgcccc ctcaggagtt caaggttgtc ttggatactg
      301 gttcttcaga cctgtgggta ccatccatct actgctccag cccagcctgc gctcatcaca
      361 aagtcttcaa ccctcttcag tcttccactt tcctggtctc aggccgacct gtgaatgttg
      421 cctatggctc aggagagatg tctggatttc ttgcctatga cactgtcaag attggagacc
      481 tcacggttgt ggcccaggca tttggcctga gcctggaaga acctggccgt ttcatggaac
      541 atgctgtctt tgatggtatc ctgggactgg gataccccaa ccttggtctt cagggagtca
      601 cacctgtctt tgacaaccta tggatacaag gcctcatccc ccagaatctc tttgccttct
      661 acttgagcag caaggatgaa aagggcagcg tgctgatgct aggtggggtg gacccctcct
      721 attaccatgg agagcttcac tgggtaccag tgtccaagcc cagctactgg cagttagctg
      781 tggacagcat ctccatgaac ggggagatca ttgcctgtga tggtggctgc caaggtatca
      841 tggatacagg gacctccttg gtgaccggcc cacgaagctc aatccttaac atccagaacc
      901 tcattggtgc caaggcttct ggtgatggcg agtacttcct caagtgtgac accatcaaca
      961 ccctacctga cattgtcttc accatcgaca gtgtgaccta cccagtgcca gccagtgcct
     1021 acatccggaa ggatcattca cacaattgcc gaagcaactt tgaagaaagc acagatgacc
     1081 cgtcagaccc tgagttgtgg gtgctggggg atgttttcct gaggctgtac ttcaccgtgt
     1141 ttgatcgggc aaataacagg attggtctgg cttctgctgc atgagtgctg ggcctccttc
     1201 agggaatggc caggcacacc cctcaacacg gaattgagta tgggtcattt catccaggaa
     1261 gctgacccca ggctaggagg agctctgcaa gaccctgttc tgtgtaagaa ataaagattg
     1321 cattcgcaaa gcc
//
