LOCUS       NM_001034147            1480 bp    mRNA    linear   ROD 26-FEB-2024
DEFINITION  Rattus norvegicus peroxisomal biogenesis factor 7 (Pex7), mRNA.
ACCESSION   NM_001034147 XM_218778
VERSION     NM_001034147.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1480)
  AUTHORS   Brites P, Motley AM, Gressens P, Mooyer PA, Ploegaert I, Everts V,
            Evrard P, Carmeliet P, Dewerchin M, Schoonjans L, Duran M, Waterham
            HR, Wanders RJ and Baes M.
  TITLE     Impaired neuronal migration and endochondral ossification in Pex7
            knockout mice: a model for rhizomelic chondrodysplasia punctata
  JOURNAL   Hum Mol Genet 12 (18), 2255-2267 (2003)
   PUBMED   12915479
REFERENCE   2  (bases 1 to 1480)
  AUTHORS   van den Brink DM, Brites P, Haasjes J, Wierzbicki AS, Mitchell J,
            Lambert-Hamill M, de Belleroche J, Jansen GA, Waterham HR and
            Wanders RJ.
  TITLE     Identification of PEX7 as the second gene involved in Refsum
            disease
  JOURNAL   Am J Hum Genet 72 (2), 471-477 (2003)
   PUBMED   12522768
REFERENCE   3  (bases 1 to 1480)
  AUTHORS   Ghys K, Fransen M, Mannaerts GP and Van Veldhoven PP.
  TITLE     Functional studies on human Pex7p: subcellular localization and
            interaction with proteins containing a peroxisome-targeting signal
            type 2 and other peroxins
  JOURNAL   Biochem J 365 (Pt 1), 41-50 (2002)
   PUBMED   11931631
REFERENCE   4  (bases 1 to 1480)
  AUTHORS   Will GK, Soukupova M, Hong X, Erdmann KS, Kiel JA, Dodt G, Kunau WH
            and Erdmann R.
  TITLE     Identification and characterization of the human orthologue of
            yeast Pex14p
  JOURNAL   Mol Cell Biol 19 (3), 2265-2277 (1999)
   PUBMED   10022913
REFERENCE   5  (bases 1 to 1480)
  AUTHORS   Purdue PE, Zhang JW, Skoneczny M and Lazarow PB.
  TITLE     Rhizomelic chondrodysplasia punctata is caused by deficiency of
            human PEX7, a homologue of the yeast PTS2 receptor
  JOURNAL   Nat Genet 15 (4), 381-384 (1997)
   PUBMED   9090383
REFERENCE   6  (bases 1 to 1480)
  AUTHORS   Motley AM, Hettema EH, Hogenhout EM, Brites P, ten Asbroek AL,
            Wijburg FA, Baas F, Heijmans HS, Tabak HF, Wanders RJ and Distel B.
  TITLE     Rhizomelic chondrodysplasia punctata is a peroxisomal protein
            targeting disease caused by a non-functional PTS2 receptor
  JOURNAL   Nat Genet 15 (4), 377-380 (1997)
   PUBMED   9090382
REFERENCE   7  (bases 1 to 1480)
  AUTHORS   Braverman N, Steel G, Obie C, Moser A, Moser H, Gould SJ and Valle
            D.
  TITLE     Human PEX7 encodes the peroxisomal PTS2 receptor and is responsible
            for rhizomelic chondrodysplasia punctata
  JOURNAL   Nat Genet 15 (4), 369-376 (1997)
   PUBMED   9090381
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC100091.1.
            
            On Oct 14, 2005 this sequence version replaced XM_218778.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC100091.1, FQ213073.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMD00132261,
                                           SAMD00132262 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1480
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1p12"
     gene            1..1480
                     /gene="Pex7"
                     /note="peroxisomal biogenesis factor 7"
                     /db_xref="GeneID:308718"
                     /db_xref="RGD:1308483"
     exon            1..164
                     /gene="Pex7"
                     /inference="alignment:Splign:2.1.0"
     CDS             50..1006
                     /gene="Pex7"
                     /note="peroxisome biogenesis factor 7"
                     /codon_start=1
                     /product="peroxisomal biogenesis factor 7"
                     /protein_id="NP_001029319.1"
                     /db_xref="GeneID:308718"
                     /db_xref="RGD:1308483"
                     /translation="MSAARTLRVPGRHGYAVEFSPYLPGRLACAAAQHYGIAGCGTLL
                     VLDQNESGLQIFRSFDWNDGLFDVTWSENNEHVLVTCSGDGSLQLWDTAKATGPLQVY
                     KEHTQEVYSVDWSQTRDEQLVVSGSWDQTVKVWDPTVGNSLCTFRGHESVIYSTIWSP
                     HIPGCFASASGDQTLRIWDVKTTGVRIVIPAHQAEILSCDWCKYNENLLVTGAVDCSL
                     RGWDLRNVRQPVFELLGHTYAIRRVKFSPFHASVLASCSYDFTVRFWNFSKPDPLLET
                     VEHHTEFTCGLDLSLQSPTEVADCSWDETVKIYNPVCLAVPG"
     exon            165..222
                     /gene="Pex7"
                     /inference="alignment:Splign:2.1.0"
     exon            223..373
                     /gene="Pex7"
                     /inference="alignment:Splign:2.1.0"
     exon            374..451
                     /gene="Pex7"
                     /inference="alignment:Splign:2.1.0"
     exon            452..560
                     /gene="Pex7"
                     /inference="alignment:Splign:2.1.0"
     exon            561..667
                     /gene="Pex7"
                     /inference="alignment:Splign:2.1.0"
     exon            668..781
                     /gene="Pex7"
                     /inference="alignment:Splign:2.1.0"
     exon            782..837
                     /gene="Pex7"
                     /inference="alignment:Splign:2.1.0"
     exon            838..937
                     /gene="Pex7"
                     /inference="alignment:Splign:2.1.0"
     exon            938..1406
                     /gene="Pex7"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 attgtttccg cgcccgggtg gggaggccga gtggcgacgg gcgggcggga tgagcgcggc
       61 gcggacgctg cgggtgccgg gtcgccacgg ctatgcggtc gagttctctc cgtacctgcc
      121 gggccgcctg gcctgtgccg ctgcgcagca ttacggcatc gcgggctgtg gaaccctatt
      181 ggtattggat caaaatgaat ctggactcca gatttttaga agctttgact ggaacgacgg
      241 cttatttgac gttacctgga gtgaaaacaa tgaacacgtc cttgtcacct gtagcggtga
      301 cggctcactg cagctctggg acactgccaa agccacaggg cctctccagg tctataaaga
      361 gcacactcag gaggtgtaca gtgttgattg gagccaaacc agagatgaac aacttgtagt
      421 gtctggctcc tgggaccaaa ctgtcaaagt gtgggatcca actgttggaa attctctgtg
      481 tacctttaga ggccacgaga gtgtcattta cagcacaatc tggtctcccc acatccctgg
      541 ttgttttgct tcagcctcag gtgatcagac tctgagaatc tgggatgtga agaccacagg
      601 agtccgaatt gtgattccag cacatcaggc cgaaatcctg agctgtgact ggtgtaaata
      661 caatgagaac ttgctggtga caggtgcggt agactgtagc ctgagaggct gggacttaag
      721 gaatgtgcga cagcctgtgt ttgaacttct tggtcacacg tacgccatta ggagggtgaa
      781 attctcacca tttcatgcct ccgtgttggc ctcttgttcc tatgatttca ctgtaagatt
      841 ctggaatttt tcaaagcctg atccacttct ggaaacagtg gagcatcaca cagagttcac
      901 ctgtggctta gacctaagtc tccagagccc cactgaggta gctgactgct cctgggatga
      961 aaccgtaaag atctacaacc ctgtctgtct cgcagttccc ggttaagcca cgctgctgtg
     1021 gtcagaacag acactgactg atgggctact tagcaacaaa ccgttaacta ctgaaaggat
     1081 agagctaggc ctttatatgt actgagattt cagaattctc agacttacat cgagatcagt
     1141 tttgaggcgt ctgataaaga tattgtatca tattgtaatc ctggtacata agccatgttt
     1201 tctgggatcc taaagaataa ttgttatgat atatcttgta atgactatta aaatgttatc
     1261 tctgtactgt aacattacat aaaatatggg aggttagatt acacgggcgg taatatattt
     1321 tatattttat cattaatata tcattttgga tgtaaaatat aatcatcctg ctgataaaaa
     1381 tcaaaataaa ctgcatttct tgatcaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
     1441 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
//
