LOCUS       NM_031350               1935 bp    mRNA    linear   ROD 28-MAR-2024
DEFINITION  Rattus norvegicus peroxisomal biogenesis factor 3 (Pex3), mRNA.
ACCESSION   NM_031350
VERSION     NM_031350.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1935)
  AUTHORS   Yonekawa,S., Furuno,A., Baba,T., Fujiki,Y., Ogasawara,Y.,
            Yamamoto,A., Tagaya,M. and Tani,K.
  TITLE     Sec16B is involved in the endoplasmic reticulum export of the
            peroxisomal membrane biogenesis factor peroxin 16 (Pex16) in
            mammalian cells
  JOURNAL   Proc Natl Acad Sci U S A 108 (31), 12746-12751 (2011)
   PUBMED   21768384
REFERENCE   2  (bases 1 to 1935)
  AUTHORS   Bharti,P., Schliebs,W., Schievelbusch,T., Neuhaus,A., David,C.,
            Kock,K., Herrmann,C., Meyer,H.E., Wiese,S., Warscheid,B., Theiss,C.
            and Erdmann,R.
  TITLE     PEX14 is required for microtubule-based peroxisome motility in
            human cells
  JOURNAL   J Cell Sci 124 (Pt 10), 1759-1768 (2011)
   PUBMED   21525035
REFERENCE   3  (bases 1 to 1935)
  AUTHORS   Ghosh,D., Lippert,D., Krokhin,O., Cortens,J.P. and Wilkins,J.A.
  TITLE     Defining the membrane proteome of NK cells
  JOURNAL   J Mass Spectrom 45 (1), 1-25 (2010)
   PUBMED   19946888
REFERENCE   4  (bases 1 to 1935)
  AUTHORS   Pinto,M.P., Grou,C.P., Fransen,M., Sa-Miranda,C. and Azevedo,J.E.
  TITLE     The cytosolic domain of PEX3, a protein involved in the biogenesis
            of peroxisomes, binds membrane lipids
  JOURNAL   Biochim Biophys Acta 1793 (11), 1669-1675 (2009)
   PUBMED   19715730
REFERENCE   5  (bases 1 to 1935)
  AUTHORS   Anthonio,E.A., Brees,C., Baumgart-Vogt,E., Hongu,T.,
            Huybrechts,S.J., Van Dijck,P., Mannaerts,G.P., Kanaho,Y., Van
            Veldhoven,P.P. and Fransen,M.
  TITLE     Small G proteins in peroxisome biogenesis: the potential
            involvement of ADP-ribosylation factor 6
  JOURNAL   BMC Cell Biol 10, 58 (2009)
   PUBMED   19686593
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 1935)
  AUTHORS   Ghaedi,K., Tamura,S., Okumoto,K., Matsuzono,Y. and Fujiki,Y.
  TITLE     The peroxin pex3p initiates membrane assembly in peroxisome
            biogenesis
  JOURNAL   Mol Biol Cell 11 (6), 2085-2102 (2000)
   PUBMED   10848631
REFERENCE   7  (bases 1 to 1935)
  AUTHORS   Gouveia,A.M., Reguenga,C., Oliveira,M.E., Eckerskorn,C.,
            Sa-Miranda,C. and Azevedo,J.E.
  TITLE     Alkaline density gradient floatation of membranes: polypeptide
            composition of the mammalian peroxisomal membrane
  JOURNAL   Anal Biochem 274 (2), 270-277 (1999)
   PUBMED   10527525
REFERENCE   8  (bases 1 to 1935)
  AUTHORS   Soukupova,M., Sprenger,C., Gorgas,K., Kunau,W.H. and Dodt,G.
  TITLE     Identification and characterization of the human peroxin PEX3
  JOURNAL   Eur J Cell Biol 78 (6), 357-374 (1999)
   PUBMED   10430017
REFERENCE   9  (bases 1 to 1935)
  AUTHORS   South,S.T. and Gould,S.J.
  TITLE     Peroxisome synthesis in the absence of preexisting peroxisomes
  JOURNAL   J Cell Biol 144 (2), 255-266 (1999)
   PUBMED   9922452
REFERENCE   10 (bases 1 to 1935)
  AUTHORS   Kammerer,S., Holzinger,A., Welsch,U. and Roscher,A.A.
  TITLE     Cloning and characterization of the gene encoding the human
            peroxisomal assembly protein Pex3p
  JOURNAL   FEBS Lett 429 (1), 53-60 (1998)
   PUBMED   9657383
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from
            JAXUCZ010000001.1.
            
            On Nov 26, 2020 this sequence version replaced NM_031350.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AB035306.1, BC062046.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760383,
                                           SAMEA5760389 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-156               JAXUCZ010000001.1  9774324-9774479     c
            157-288             JAXUCZ010000001.1  9767866-9767997     c
            289-370             JAXUCZ010000001.1  9763164-9763245     c
            371-414             JAXUCZ010000001.1  9757809-9757852     c
            415-539             JAXUCZ010000001.1  9756294-9756418     c
            540-606             JAXUCZ010000001.1  9755995-9756061     c
            607-661             JAXUCZ010000001.1  9755841-9755895     c
            662-827             JAXUCZ010000001.1  9754764-9754929     c
            828-898             JAXUCZ010000001.1  9747044-9747114     c
            899-1021            JAXUCZ010000001.1  9745909-9746031     c
            1022-1118           JAXUCZ010000001.1  9736190-9736286     c
            1119-1935           JAXUCZ010000001.1  9732641-9733457     c
FEATURES             Location/Qualifiers
     source          1..1935
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1p13"
     gene            1..1935
                     /gene="Pex3"
                     /note="peroxisomal biogenesis factor 3"
                     /db_xref="GeneID:83519"
                     /db_xref="RGD:621636"
     exon            1..156
                     /gene="Pex3"
                     /inference="alignment:Splign:2.1.0"
     CDS             84..1202
                     /gene="Pex3"
                     /note="peroxin-3; peroxisomal assembly protein PEX3"
                     /codon_start=1
                     /product="peroxisomal biogenesis factor 3"
                     /protein_id="NP_112640.1"
                     /db_xref="GeneID:83519"
                     /db_xref="RGD:621636"
                     /translation="MLRSMWNFLKRHKKKCIFLGTVLGGVYILGKYGQKKLREIQERE
                     AAEYIAQARRQYHFESNQRTCNMTVLSMLPTLREALMQQLNSESLTALLKNRPSNKLE
                     IWEDLKIISFTRSIVAVYSTCMLVVLLRVQLNIIGGYIYLDNATVGKNGTSILAPPDV
                     QQQYLSSIQHLLGDGLTELVTVIKQAVQRILGSISLKHSLSLLDLEQKLKEIRTLVEQ
                     HRSCWNDKDASKSSLCHYMMPDEETPLAAQAYGLSPRDITTIKLLNETRDMLESPDFS
                     TVLNTCLNRGFSRLLDNMAEFFRPTEQDLQHGNSINSLSSVSLPLAKIIPIVNGQIHS
                     VCSETPSHFVQDLLMMEQVKDFAANVYEAFSTPQQLEK"
     exon            157..288
                     /gene="Pex3"
                     /inference="alignment:Splign:2.1.0"
     exon            289..370
                     /gene="Pex3"
                     /inference="alignment:Splign:2.1.0"
     exon            371..414
                     /gene="Pex3"
                     /inference="alignment:Splign:2.1.0"
     exon            415..539
                     /gene="Pex3"
                     /inference="alignment:Splign:2.1.0"
     exon            540..606
                     /gene="Pex3"
                     /inference="alignment:Splign:2.1.0"
     exon            607..661
                     /gene="Pex3"
                     /inference="alignment:Splign:2.1.0"
     exon            662..827
                     /gene="Pex3"
                     /inference="alignment:Splign:2.1.0"
     exon            828..898
                     /gene="Pex3"
                     /inference="alignment:Splign:2.1.0"
     exon            899..1021
                     /gene="Pex3"
                     /inference="alignment:Splign:2.1.0"
     exon            1022..1118
                     /gene="Pex3"
                     /inference="alignment:Splign:2.1.0"
     exon            1119..1935
                     /gene="Pex3"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ccgggccaga ttgacggaag acacggtttc ctggtgagcc agtccctctc ccctaggcaa
       61 cccacacaac ccggggtctg aagatgctga gatcaatgtg gaattttctg aaacgtcaca
      121 aaaagaaatg catcttcctg ggcacagtcc ttggaggagt ctatatcctg ggaaaatatg
      181 gacagaaaaa acttagagaa atacaagaaa gagaagctgc agagtacatt gcccaagctc
      241 ggcgacagta ccattttgaa agtaaccaga ggacttgcaa tatgacagtg ctgtccatgc
      301 tgccaacact gagagaggcc ttaatgcagc agctcaactc ggagagtctg acagctttgt
      361 tgaaaaacag gccttcaaac aagctggaaa tatgggagga tctaaagata ataagtttca
      421 caagaagtat tgtagctgtg tacagcacat gtatgctggt ggttcttttg cgagtccagc
      481 tgaacataat tggtggatat atttacctgg ataatgcaac agttggcaaa aatggcacta
      541 gcatcctagc tcccccagat gtacagcaac agtatttatc aagtattcaa cacctccttg
      601 gagatggcct gacagagttg gtcactgtca ttaaacaagc tgtgcagagg atcttaggaa
      661 gtatttctct taaacattcc ttgtcccttt tggacttgga gcagaaactg aaagaaataa
      721 gaactcttgt tgagcaacat cgatcttgct ggaatgataa agacgcatcc aagtcttccc
      781 tgtgccacta catgatgcca gacgaggaga cgccgctggc agcgcaggct tatgggcttt
      841 ctcccagaga tattaccact attaaacttc tcaatgagac aagagacatg ctggaaagtc
      901 cagatttcag tacagttctg aatacctgtt taaacagagg cttcagtcgg cttctagaca
      961 atatggcgga gttcttccga cccactgagc aggacctgca gcatggtaac tccataaaca
     1021 gtctgtccag tgtcagcctc cctttagcca agataatccc catagtgaac ggacagatcc
     1081 actccgtctg cagtgagaca cccagtcact tcgtgcagga tctgctgatg atggagcaag
     1141 tgaaagactt tgctgccaac gtgtacgaag cattcagcac cccccaacaa ctggagaaat
     1201 gattgttttc tttcaagaaa aaccacagtg gattcatcta cattaaaaag tactctgaat
     1261 aaatcaccta tacctagagt gacaatttgc aaccaaatgc ctaataaaat atattcttga
     1321 gccaagtctt catctcataa tgaagtagat tcatttagca ccttactgta tttttaattc
     1381 agcacagtct acttcctcag gtgtatctaa ctgtgcagag atcacgtcag catcaatcat
     1441 gattccttaa agtctggata gctgatccaa acaagtaggg cttttataca tacatggaat
     1501 ggaatgtggt gtcctttcac acatgtaatg agggaaaatg tgtcttgaaa aggagatcta
     1561 ggctgtttaa ctaattatgg cgtttcctgg actctgaagt aagcaagagc aagccagatc
     1621 ctcttcagtc gcccttagaa ggcacccgtg atttgctcac acatacctac gcaggggctt
     1681 atcttctaga aatgagtggg tttccacacc tgtggtcact tacttctctg cactgtcctg
     1741 tcagtattta tttgcagcat tttctaagct tcattagcag ccctcagaag gctgcatata
     1801 gattcttcaa gctaatgttt atgttgttta ctcacaatta ttaataatta caggtttatt
     1861 catttatgta taaattaata actttgtatt gattttgagt ataataagtt gttacaataa
     1921 actattttaa taaaa
//
