LOCUS       NM_053487               2259 bp    mRNA    linear   ROD 04-JUN-2024
DEFINITION  Rattus norvegicus peroxisomal biogenesis factor 11 alpha (Pex11a),
            mRNA.
ACCESSION   NM_053487
VERSION     NM_053487.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2259)
  AUTHORS   Koch,J., Pranjic,K., Huber,A., Ellinger,A., Hartig,A., Kragler,F.
            and Brocard,C.
  TITLE     PEX11 family members are membrane elongation factors that
            coordinate peroxisome proliferation and maintenance
  JOURNAL   J Cell Sci 123 (Pt 19), 3389-3400 (2010)
   PUBMED   20826455
REFERENCE   2  (bases 1 to 2259)
  AUTHORS   Matsuzaki,T. and Fujiki,Y.
  TITLE     The peroxisomal membrane protein import receptor Pex3p is directly
            transported to peroxisomes by a novel Pex19p- and Pex16p-dependent
            pathway
  JOURNAL   J Cell Biol 183 (7), 1275-1286 (2008)
   PUBMED   19114594
REFERENCE   3  (bases 1 to 2259)
  AUTHORS   Delille,H.K. and Schrader,M.
  TITLE     Targeting of hFis1 to peroxisomes is mediated by Pex19p
  JOURNAL   J Biol Chem 283 (45), 31107-31115 (2008)
   PUBMED   18782765
REFERENCE   4  (bases 1 to 2259)
  AUTHORS   Wu,Y. and Smas,C.M.
  TITLE     Wdnm1-like, a new adipokine with a role in MMP-2 activation
  JOURNAL   Am J Physiol Endocrinol Metab 295 (1), E205-E215 (2008)
   PUBMED   18492766
REFERENCE   5  (bases 1 to 2259)
  AUTHORS   Kikuchi,M., Hatano,N., Yokota,S., Shimozawa,N., Imanaka,T. and
            Taniguchi,H.
  TITLE     Proteomic analysis of rat liver peroxisome: presence of
            peroxisome-specific isozyme of Lon protease
  JOURNAL   J Biol Chem 279 (1), 421-428 (2004)
   PUBMED   14561759
REFERENCE   6  (bases 1 to 2259)
  AUTHORS   South,S.T. and Gould,S.J.
  TITLE     Peroxisome synthesis in the absence of preexisting peroxisomes
  JOURNAL   J Cell Biol 144 (2), 255-266 (1999)
   PUBMED   9922452
REFERENCE   7  (bases 1 to 2259)
  AUTHORS   Schrader,M., Reuber,B.E., Morrell,J.C., Jimenez-Sanchez,G.,
            Obie,C., Stroh,T.A., Valle,D., Schroer,T.A. and Gould,S.J.
  TITLE     Expression of PEX11beta mediates peroxisome proliferation in the
            absence of extracellular stimuli
  JOURNAL   J Biol Chem 273 (45), 29607-29614 (1998)
   PUBMED   9792670
REFERENCE   8  (bases 1 to 2259)
  AUTHORS   Abe,I., Okumoto,K., Tamura,S. and Fujiki,Y.
  TITLE     Clofibrate-inducible, 28-kDa peroxisomal integral membrane protein
            is encoded by PEX11
  JOURNAL   FEBS Lett 431 (3), 468-472 (1998)
   PUBMED   9714566
REFERENCE   9  (bases 1 to 2259)
  AUTHORS   Passreiter,M., Anton,M., Lay,D., Frank,R., Harter,C., Wieland,F.T.,
            Gorgas,K. and Just,W.W.
  TITLE     Peroxisome biogenesis: involvement of ARF and coatomer
  JOURNAL   J Cell Biol 141 (2), 373-383 (1998)
   PUBMED   9548716
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AJ224120.1, BC061835.1 and JAXUCZ010000001.1.
            
            On Oct 13, 2005 this sequence version replaced NM_053487.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC061835.1, SRR22582416.651682.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN12840110, SAMN12840117
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-558               AJ224120.1         33-590
            559-666             BC061835.1         522-629
            667-1049            AJ224120.1         699-1081
            1050-2259           JAXUCZ010000001.1  143089410-143090619 c
FEATURES             Location/Qualifiers
     source          1..2259
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q31"
     gene            1..2259
                     /gene="Pex11a"
                     /gene_synonym="Pmp26p"
                     /note="peroxisomal biogenesis factor 11 alpha"
                     /db_xref="GeneID:85249"
                     /db_xref="RGD:619842"
     exon            1..162
                     /gene="Pex11a"
                     /gene_synonym="Pmp26p"
                     /inference="alignment:Splign:2.1.0"
     CDS             107..847
                     /gene="Pex11a"
                     /gene_synonym="Pmp26p"
                     /note="PMP28; rnPEX11p; PEX11alpha; peroxin-11A;
                     pex11palpha; peroxisomal coatomer receptor; peroxisomal
                     membrane protein 26; 28 kDa peroxisomal integral membrane
                     protein; PEX11-alpha; protein PEX11 homolog alpha;
                     peroxisomal biogenesis factor 11A; peroxisomal membrane
                     protein Pmp26p (Peroxin-11)"
                     /codon_start=1
                     /product="peroxisomal membrane protein 11A"
                     /protein_id="NP_445939.1"
                     /db_xref="GeneID:85249"
                     /db_xref="RGD:619842"
                     /translation="MDAFIRVANQSQGRDRLFRATQHACMLLRYLLESKAGKEAVVTK
                     LKNLETSVSTGRKWFRLGNVLHAIQATEQSIQATDLVPRLCLTLANLNRVVYYICDTV
                     LWAKSVGLTSGINREKWQMRAARHYYYFLLLSLVRDLYEVLLHMGQVARDRAKREKSS
                     GDPPKYSVANEESEWLQSFLLLLFQSLKRNPPLFLDTVKNFCDILIPLNQLGIYKSNL
                     GVVGFGGLVSSVAGLITVVYPQLKLKAR"
     exon            163..278
                     /gene="Pex11a"
                     /gene_synonym="Pmp26p"
                     /inference="alignment:Splign:2.1.0"
     exon            279..2259
                     /gene="Pex11a"
                     /gene_synonym="Pmp26p"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cccacccacc cggcgactaa tctgatcccg gctgtccccc gggaccagcg aggtcccaga
       61 agacccacga gggagcgggc gtaacgcgtg gctgcgggtg ggagccatgg acgccttcat
      121 ccgagtcgcc aaccaaagcc aaggtcggga ccgacttttc agagccactc aacacgcatg
      181 catgttgctt agatatttgt tagagtctaa ggctggcaaa gaggcggtgg taacgaagct
      241 caagaatctg gagactagtg tgagcactgg ccgtaaatgg ttcagactag gcaacgtgct
      301 ccatgccatc caggccactg agcagagcat ccaagccact gaccttgtgc cccgcctatg
      361 cctaacatta gccaacctga accgcgtggt ttattacatc tgtgacactg tcctctgggc
      421 gaagagtgtg ggtctgacat ctggaatcaa cagagagaag tggcaaatgc gggcggcccg
      481 ccactactac tatttcctct tgctgagcct ggtccgggat ctgtatgagg tcttgctgca
      541 tatgggacaa gttgcacgtg acagagcaaa gagagagaag tcctccgggg accctcctaa
      601 gtacagcgtc gctaatgaag aaagtgaatg gctccagtcc ttcctcctcc tcctcttcca
      661 gtctctaaag cgaaatccgc ccttattcct ggacaccgtg aagaacttct gtgacatcct
      721 gatccctttg aaccagctcg ggatctacaa gtccaacctt ggcgtggtag gatttggagg
      781 tctcgtgtcc tctgtggctg gcctcatcac tgtggtgtat cctcagttga aactgaaggc
      841 ccgctagggt gtttggaaaa tttaagactg acgttcagtg gagcaaacat ttgcttttgt
      901 catgatgtct actgtactta atttttttta atcatgtgag catcttacca accggtgatg
      961 tgagcagagg taggacccac aacggagcct gaagactgat gacgtttttg taaacacggc
     1021 agtaacttct gcacatttcc ccttcagtga acattgctga gcatcttttc tgtacatagt
     1081 aagagctcag tatatgctga acaaataaag atagaaagga acgaagtcat cgaaaaccca
     1141 aggaaactag aattacagat cgggtcgcat gggttttgat ttcacacaag cacatcaggg
     1201 cccggcacag cactcctggc tctggttaag gcttcccttt tctcccatct gtggttgtta
     1261 tcccccagcc ccacagatgt cagtagtggg atggagggga gctgtgctca gagcctggta
     1321 acctgttggc cctggtcatt gctgtagttg tgtcctgacc atgttcagaa gtagactcag
     1381 aaaaacatca gtacctttgt gccggaagcg gtgtccacag gtaatgctgt gagtaagcaa
     1441 gaaaacagca ggagggacca gaggtgaaag taggtgggag gtcaccactg cccattacat
     1501 aatccatcac agataaggaa attgacaata caaaacaaag ccactagcac acaggtttat
     1561 tctgattctt cccaagatga ttcccgtgat ctcatgaccc tcagcagcat ttccaggctc
     1621 aaagccctta gtcccttaac atgcccctcc ccctgctggc ctggaacgtc catccacggt
     1681 ctctgttcta gtctataaag tgcaaaacaa tgtagactca cccaggctgg ttttatttaa
     1741 agctacataa cagtttgggc aattccacag tatttttcat caaaataaga gaattaaaat
     1801 tcttctgcct atgaatgtag gaatgtcagt tttctgtgac aaatctgatt tttctcagga
     1861 caactgggag gggcgggaaa gagctatcgg gccagtggag agggtgtggg gacgctcttc
     1921 acggctcagc cttcctgtct tgagcttggt ttaggtgtgt gaagtgggag acactggcca
     1981 gcaggtgggc cagtgtctca gcaccgataa agccgtgtac agttaagtgg aaatgagaac
     2041 tctgcactaa gtaactgctt tccgtgaatg tgaagaagat tcttgcaaag tggactcagg
     2101 accttggcac tgtatttgta aaatgataat gtgctttgag aaaaccttag ggggaggggg
     2161 gatgaaagaa attaaagtgg taaaacaaga caaatatgag taaatgccta tttttactgt
     2221 aacattaatt atgtctaata aatttctaga taaaattga
//
