LOCUS       NM_001109405            1699 bp    mRNA    linear   ROD 21-MAR-2023
DEFINITION  Rattus norvegicus peroxisomal biogenesis factor 10 (Pex10), mRNA.
ACCESSION   NM_001109405 XM_001057106
VERSION     NM_001109405.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1699)
  AUTHORS   Hanson MG, Fregoso VL, Vrana JD, Tucker CL and Niswander LA.
  TITLE     Peripheral nervous system defects in a mouse model for peroxisomal
            biogenesis disorders
  JOURNAL   Dev Biol 395 (1), 84-95 (2014)
   PUBMED   25176044
REFERENCE   2  (bases 1 to 1699)
  AUTHORS   Bharti P, Schliebs W, Schievelbusch T, Neuhaus A, David C, Kock K,
            Herrmann C, Meyer HE, Wiese S, Warscheid B, Theiss C and Erdmann R.
  TITLE     PEX14 is required for microtubule-based peroxisome motility in
            human cells
  JOURNAL   J Cell Sci 124 (Pt 10), 1759-1768 (2011)
   PUBMED   21525035
REFERENCE   3  (bases 1 to 1699)
  AUTHORS   Kikuchi M, Hatano N, Yokota S, Shimozawa N, Imanaka T and Taniguchi
            H.
  TITLE     Proteomic analysis of rat liver peroxisome: presence of
            peroxisome-specific isozyme of Lon protease
  JOURNAL   J Biol Chem 279 (1), 421-428 (2004)
   PUBMED   14561759
REFERENCE   4  (bases 1 to 1699)
  AUTHORS   Warren DS, Wolfe BD and Gould SJ.
  TITLE     Phenotype-genotype relationships in PEX10-deficient peroxisome
            biogenesis disorder patients
  JOURNAL   Hum Mutat 15 (6), 509-521 (2000)
   PUBMED   10862081
REFERENCE   5  (bases 1 to 1699)
  AUTHORS   Chang CC, Warren DS, Sacksteder KA and Gould SJ.
  TITLE     PEX12 interacts with PEX5 and PEX10 and acts downstream of receptor
            docking in peroxisomal matrix protein import
  JOURNAL   J Cell Biol 147 (4), 761-774 (1999)
   PUBMED   10562279
REFERENCE   6  (bases 1 to 1699)
  AUTHORS   South ST and Gould SJ.
  TITLE     Peroxisome synthesis in the absence of preexisting peroxisomes
  JOURNAL   J Cell Biol 144 (2), 255-266 (1999)
   PUBMED   9922452
REFERENCE   7  (bases 1 to 1699)
  AUTHORS   Okumoto K, Itoh R, Shimozawa N, Suzuki Y, Tamura S, Kondo N and
            Fujiki Y.
  TITLE     Mutations in PEX10 is the cause of Zellweger peroxisome deficiency
            syndrome of complementation group B
  JOURNAL   Hum Mol Genet 7 (9), 1399-1405 (1998)
   PUBMED   9700193
REFERENCE   8  (bases 1 to 1699)
  AUTHORS   Warren DS, Morrell JC, Moser HW, Valle D and Gould SJ.
  TITLE     Identification of PEX10, the gene defective in complementation
            group 7 of the peroxisome-biogenesis disorders
  JOURNAL   Am J Hum Genet 63 (2), 347-359 (1998)
   PUBMED   9683594
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473968.1.
            
            On Oct 4, 2007 this sequence version replaced XM_001057106.1.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMD00132261,
                              SAMD00132262 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1699
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="5"
                     /map="5q36"
     gene            1..1699
                     /gene="Pex10"
                     /note="peroxisomal biogenesis factor 10"
                     /db_xref="GeneID:680424"
                     /db_xref="RGD:1591776"
     exon            1..197
                     /gene="Pex10"
                     /inference="alignment:Splign:2.1.0"
     CDS             92..1066
                     /gene="Pex10"
                     /EC_number="2.3.2.27"
                     /codon_start=1
                     /product="peroxisome biogenesis factor 10"
                     /protein_id="NP_001102875.1"
                     /db_xref="GeneID:680424"
                     /db_xref="RGD:1591776"
                     /translation="MAQAGPPEVIRAAQKDEYYLGGLRSAAGGALHSLAGAKKWLEWR
                     KEIELLSDIAYFGLTTIAGYQTLGEEYVGIIQVDPSRQRVPSRLRRGVLVALHAVLPY
                     LLDKALLPLEQELQAEGDGTRASQGSLLPGGRSRSGARRWVRHHAATLTEQQRRALQR
                     AVFILRQGFACLHRLHVAWFYIHGTFYHLAKRLAGITYLRTRRLPGEDLRACTSYRLL
                     GLISLLHLALSLGLQLYSFRQKQRARKEWRLHRNLSHRRSSLEDRAVCRAPLCTLCLE
                     ERRHSTATPCGHLFCWECITEWCNTKTECPLCREKFPPQKLVYLRHYR"
     exon            198..278
                     /gene="Pex10"
                     /inference="alignment:Splign:2.1.0"
     exon            279..685
                     /gene="Pex10"
                     /inference="alignment:Splign:2.1.0"
     exon            686..861
                     /gene="Pex10"
                     /inference="alignment:Splign:2.1.0"
     exon            862..997
                     /gene="Pex10"
                     /inference="alignment:Splign:2.1.0"
     exon            998..1699
                     /gene="Pex10"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cctgcgcccc acgacagagg tacgtcgagc gtcacaggcc ccgcccacga ggtgcgccgg
       61 cgcggtgcga gctcaccgac cgagtagagc catggcgcag gcgggtcctc cagaagtgat
      121 ccgggcggcg cagaaggacg agtactacct gggaggcctg cggagcgcgg cgggtggagc
      181 gctgcacagc ctagcgggtg caaagaaatg gctggaatgg aggaaagaga tcgagttgct
      241 ctcagacata gcctactttg gcctcaccac aattgcaggc taccagacac ttggagagga
      301 gtacgtcggg atcatccaag tggacccatc ccggcagcgt gtgccctcca ggctccgacg
      361 tggagtgctg gttgccctgc atgctgtctt gccctacctg ctagacaagg cactgctgcc
      421 cctggagcag gagctgcaag ctgagggcga cggcacccgg gcctcccagg ggagtctgct
      481 acccggagga cgcagccggt caggggcacg gcgctgggtg cgtcaccacg cagctaccct
      541 gactgaacaa cagaggaggg ccctccagcg ggcagtcttt atcctgagac agggcttcgc
      601 ctgcctccac cggctccatg tggcttggtt ttatatccat ggtaccttct accacctggc
      661 caagagactg gcagggatca cttatctccg cactcgccgc ctgccgggag aggacctgag
      721 ggcttgcact agctaccgac tgctgggact catctccctg ctgcatctgg cattgtcact
      781 ggggctgcag ttgtacagct tcaggcagaa gcagcgagcc aggaaggagt ggaggctgca
      841 ccgaaatctg tcccaccgca ggagttccct tgaggacaga gcagtttgta gagccccact
      901 ctgcaccctg tgcttggagg agcgaagaca ctccacagcc acaccttgtg gccatctctt
      961 ctgctgggag tgcattaccg agtggtgcaa caccaagaca gagtgtcccc tatgccggga
     1021 gaagttccca ccccagaagc tggtctacct gaggcactac cgctgacagc tctaagaagt
     1081 gaatggaagc ccatggacaa gtttctcaga actgtggctg cacagaaaca taaaacctcc
     1141 acactgctct tttgttgcat aagctactac agttacctgg aaagaaaggg agtcaggcgc
     1201 aagtggggaa aactcaattt gggggtagga gagtttgttg cacgtaatct atggcttctt
     1261 cagtctctgg agatagtgga ctcccccctc ccttcccaag ccacacagct gagaactgct
     1321 tcagaaggtc agggtgtttt actcaggtct gtaaagaggc agccaccatt gggctgggag
     1381 aggcatggct caggttaggc tggaagcgaa gtgtagaact ctgggctcac tgccgtcagt
     1441 acccctccta aaacaccaca tgcttaatcc atgttgccaa ctccttaagg aaatgaaggg
     1501 ctgtgctgga cagatggctc agaggctgag cactggatgt tcttccagag gccctgagtt
     1561 caattcccag caaccatcta ttctggaatc tgatgccctt tctgacagaa cactaaaata
     1621 cataacaaat aaacctttac aaaaagtaca acttgaaggt cttcatctcc ccgagctgca
     1681 catttttaca actgtatta
//
