LOCUS       NM_001106265            1890 bp    mRNA    linear   ROD 21-MAR-2023
DEFINITION  Rattus norvegicus p53 apoptosis effector related to PMP22 (Perp),
            mRNA.
ACCESSION   NM_001106265 XM_001072627 XM_214953
VERSION     NM_001106265.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1890)
  AUTHORS   Fouillade C, Baron-Menguy C, Domenga-Denier V, Thibault C, Takamiya
            K, Huganir R and Joutel A.
  TITLE     Transcriptome analysis for Notch3 target genes identifies Grip2 as
            a novel regulator of myogenic response in the cerebrovasculature
  JOURNAL   Arterioscler Thromb Vasc Biol 33 (1), 76-86 (2013)
   PUBMED   23117660
REFERENCE   2  (bases 1 to 1890)
  AUTHORS   Jheon AH, Mostowfi P, Snead ML, Ihrie RA, Sone E, Pramparo T,
            Attardi LD and Klein OD.
  TITLE     PERP regulates enamel formation via effects on cell-cell adhesion
            and gene expression
  JOURNAL   J Cell Sci 124 (Pt 5), 745-754 (2011)
   PUBMED   21285247
REFERENCE   3  (bases 1 to 1890)
  AUTHORS   Ketteler R, Sun Z, Kovacs KF, He WW and Seed B.
  TITLE     A pathway sensor for genome-wide screens of intracellular
            proteolytic cleavage
  JOURNAL   Genome Biol 9 (4), R64 (2008)
   PUBMED   18387192
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 1890)
  AUTHORS   Mootha VK, Bunkenborg J, Olsen JV, Hjerrild M, Wisniewski JR, Stahl
            E, Bolouri MS, Ray HN, Sihag S, Kamal M, Patterson N, Lander ES and
            Mann M.
  TITLE     Integrated analysis of protein composition, tissue diversity, and
            gene regulation in mouse mitochondria
  JOURNAL   Cell 115 (5), 629-640 (2003)
   PUBMED   14651853
REFERENCE   5  (bases 1 to 1890)
  AUTHORS   Attardi LD, Reczek EE, Cosmas C, Demicco EG, McCurrach ME, Lowe SW
            and Jacks T.
  TITLE     PERP, an apoptosis-associated target of p53, is a novel member of
            the PMP-22/gas3 family
  JOURNAL   Genes Dev 14 (6), 704-718 (2000)
   PUBMED   10733530
  REMARK    Erratum:[Genes Dev 2000 Jul 15;14(14):1835]
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC166608.1.
            
            On Apr 29, 2008 this sequence version replaced NM_001106265.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC166608.1, DN934252.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5756307, SAMEA5760383
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1890
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1p12"
     gene            1..1890
                     /gene="Perp"
                     /note="p53 apoptosis effector related to PMP22"
                     /db_xref="GeneID:292949"
                     /db_xref="RGD:1310294"
     exon            1..318
                     /gene="Perp"
                     /inference="alignment:Splign:2.1.0"
     CDS             105..686
                     /gene="Perp"
                     /note="PERP, TP53 apoptosis effector"
                     /codon_start=1
                     /product="p53 apoptosis effector related to PMP-22"
                     /protein_id="NP_001099735.1"
                     /db_xref="GeneID:292949"
                     /db_xref="RGD:1310294"
                     /translation="MLRCGLACERCRWILPLLLLSAIAFDIIALSGRGWLQSSNHIQT
                     SSLWWRCFDEGGGSGSYDDGCQSLMEYAWGRAAAATLFCGFIILVICFILSFFALCGP
                     QMLVFLRVIGGLLALAAVFQIISLVIYPVKYTQTFRLHDNPAVNYIYNWAYGFGWAAT
                     IILIGCSFFFCCLPNYEDDLLGNAKPRYFYTSA"
     exon            319..459
                     /gene="Perp"
                     /inference="alignment:Splign:2.1.0"
     exon            460..1872
                     /gene="Perp"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gcgggagccg cctcttcctt tagtggcggt gtcggcgctc gcaggaccac tctcggccgc
       61 tgctccagcc ccgcgttcct ccgctccgcg ccgccaccga cgacatgctg cgctgcggcc
      121 tggcctgcga gcgctgcagg tggatcctgc ccctgctgct gctcagtgcc atcgccttcg
      181 acatcatcgc gctgtccggc cgcggctggc tgcagtctag caaccacatc cagacgtcct
      241 cgctttggtg gaggtgtttc gacgagggcg gtggcagcgg ctcctacgac gatggctgcc
      301 agagcctcat ggaatacgcc tggggccgag cagctgctgc cactctcttc tgtggattca
      361 tcatcctggt catctgcttc atcctctcgt tcttcgccct gtgtggaccc cagatgcttg
      421 ttttcctgag agtgattgga ggccttctcg cactggctgc tgtattccag atcatctccc
      481 tggttatcta tcccgtgaag tacacacaaa ccttcaggct tcatgataat cccgctgtta
      541 attacatcta caactgggcc tatggcttcg gatgggcagc cacgatcatc ttgattggtt
      601 gctctttctt cttctgctgc ctccccaact acgaggatga ccttctgggc aatgcaaagc
      661 ccaggtactt ctatacatct gcctaatgtg gagggagatc ctgagaaaag cctgctgcaa
      721 gatgcatgtg aggaggaaag tgttctccaa ggagcaaaga acctatgttt gggcagtgtt
      781 catatgagtg gaaatgctag aataaatgct aaagaaaatt cttcataaat agtgttaagt
      841 ttcatgtccc tgtgtatgtc ttgcggagtt aaaagagact tgtttctgtt tgctcagtat
      901 atgctgactt ctccttgcac caattctgta tcatttaaac ttcatttgtt aaagagcatg
      961 cccgggaaac ttgctaagta agaaatgcta tggcttctca tttaataatc tgatgaagct
     1021 tttgtttttc cagagagaat gggttgtttc tacagggaat gggttggcta cagagcagga
     1081 aagctactgg caaattccag tgaccaaata ttctgaaatt aatgtttttc ttaaacacac
     1141 acacacacac acacacacac acacacacac acacacacac acgccctttt tgagttttca
     1201 gttacataaa gaagcagagt ggtgtcctac gtgagcatcg atgttttgaa cagttattgt
     1261 ttcgctcagc tttgtgttga ttttctccga tatgcgggga aagtgaaaca tggccgttgt
     1321 cactactgaa tgctaaggtg aattttactc ttttgacgta gattagaggg gtgggtgtgg
     1381 gaagaagcca tattaacaaa tctgtacagt gttgcgtgta tgtttagaac cagcgtagac
     1441 tagatgggag ggtggactag gccttattcc tcccgaccga tggatgtgat gaggtcgggt
     1501 aggaaggcct atgagggtta ccattcagac atcccgggag aagacatatc aatgcccctc
     1561 tcagccttaa ctgagctcta ctgacagaca gctagaatag atttgaactg taacagaaac
     1621 ctaaatgtaa ttacaaacct ggtcttcctc ggtaaacaga cttaacatat ctgtataata
     1681 catacaaggg ggaaatttgg gaatgagttt ctctgaatac atattggaag ggctgttatt
     1741 attttttctt accatttata ctcactgaat ggaaactagc ttattttaaa tatcagaaca
     1801 ctattttgta agttgcagcc aagacaattg cagttttcat gaccagcttc cccaataaac
     1861 cagatgttca aaaaaaaaaa aaaaaaaaaa
//
