LOCUS       NM_001007634            1550 bp    mRNA    linear   ROD 02-JUN-2024
DEFINITION  Rattus norvegicus pelota mRNA surveillance and ribosome rescue
            factor (Pelo), mRNA.
ACCESSION   NM_001007634 XM_215478
VERSION     NM_001007634.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1550)
  AUTHORS   Nyamsuren,G., Kata,A., Xu,X., Raju,P., Dressel,R., Engel,W.,
            Pantakani,D.V. and Adham,I.M.
  TITLE     Pelota regulates the development of extraembryonic endoderm through
            activation of bone morphogenetic protein (BMP) signaling
  JOURNAL   Stem Cell Res 13 (1), 61-74 (2014)
   PUBMED   24835669
REFERENCE   2  (bases 1 to 1550)
  AUTHORS   Franckenberg,S., Becker,T. and Beckmann,R.
  TITLE     Structural view on recycling of archaeal and eukaryotic ribosomes
            after canonical termination and ribosome rescue
  JOURNAL   Curr Opin Struct Biol 22 (6), 786-796 (2012)
   PUBMED   23031510
  REMARK    Review article
REFERENCE   3  (bases 1 to 1550)
  AUTHORS   Adham,I.M., Sallam,M.A., Steding,G., Korabiowska,M., Brinck,U.,
            Hoyer-Fender,S., Oh,C. and Engel,W.
  TITLE     Disruption of the pelota gene causes early embryonic lethality and
            defects in cell cycle progression
  JOURNAL   Mol Cell Biol 23 (4), 1470-1476 (2003)
   PUBMED   12556505
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC083637.1.
            
            On Nov 29, 2004 this sequence version replaced XM_215478.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC083637.1, FQ214039.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132262
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1550
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="2"
                     /map="2q14"
     gene            1..1550
                     /gene="Pelo"
                     /note="pelota mRNA surveillance and ribosome rescue
                     factor"
                     /db_xref="GeneID:294754"
                     /db_xref="RGD:1359591"
     exon            1..881
                     /gene="Pelo"
                     /inference="alignment:Splign:2.1.0"
     CDS             156..1313
                     /gene="Pelo"
                     /note="pelota homolog"
                     /codon_start=1
                     /product="protein pelota homolog"
                     /protein_id="NP_001007635.1"
                     /db_xref="GeneID:294754"
                     /db_xref="RGD:1359591"
                     /translation="MKLVRKDIEKDNAGQVTLVPEEPEDMWHTYNLVQVGDSLRASTI
                     RKVQTESSTGSVGSNRVRTTLTLCVEAIDFDSQACQLRVKGTNIQENEYVKMGAYHTI
                     ELEPNRQFTLAKKQWDSVVLERIEQACDPAWSADVAAVVMQEGLAHVCLVTPSMTLTR
                     AKVEVNIPRKRKGNCSQHDRALERFYEQVVQAIQRHINFEVVKCILVASPGFVREQFC
                     DYMFQQAVKTDNKVLLENRSKFLQVHASSGHKYSLKEVLCDPTVASRLSDTKAAGEVK
                     ALDDFYKMLQHEPDRAFYGLKQVERANEALAIDTLLISDELFRHQDVATRSRYVRLVD
                     SVKENAGTVRIFSSLHVSGEQLGQLTGVAAILRFPVPELSDQEDDSSSEED"
     exon            882..1479
                     /gene="Pelo"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ggagaaaagg cgtgggggaa gcgccgtccc gggctacagg agtcagaggt agtgtttcct
       61 tccggtctga actcaccgcc ccttccctgc cccgccccct cccgcctggg ggcttccaag
      121 cgcctcctat tctgaagtga gcccctgccg cggtcatgaa gcttgtgagg aaagatatcg
      181 agaaggacaa tgcgggccag gtcaccctcg tcccggagga gcccgaggac atgtggcaca
      241 cctacaatct agtgcaggtg ggcgacagcc tgcgcgcctc caccatccgt aaggtccaga
      301 ccgagtcctc cacaggcagc gtggggagca accgtgtccg caccaccctc actctttgcg
      361 tggaggccat cgacttcgac tcccaggcct gccagctgcg ggttaagggc accaatattc
      421 aagagaatga gtatgtcaag atgggggctt accacaccat cgaactggag cccaaccgcc
      481 agttcaccct ggccaagaaa cagtgggaca gtgtggttct ggaacgcatc gagcaggcat
      541 gtgacccggc ctggagcgct gatgtggcag ctgtggtcat gcaggagggc ctcgcccatg
      601 tctgcttagt cacgcccagc atgaccctta cccgtgccaa ggtggaggtg aacatcccca
      661 ggaaacggaa aggcaactgt tcccagcatg accgggcctt ggagcggttc tatgaacaag
      721 tggtccaggc catccagcgc cacataaact ttgaggttgt aaagtgcatt ctggtggcca
      781 gccctggatt tgtgcgagag cagttctgcg attacatgtt tcaacaagct gtgaagaccg
      841 acaacaaggt gctcctggaa aaccgctcca aattccttca ggtacacgcc tcctctggac
      901 acaagtactc cctgaaagag gtcctatgtg atcctactgt agcgagccgc ctttcagaca
      961 cgaaagctgc cggggaagta aaagccttgg atgacttcta caaaatgtta cagcacgaac
     1021 ctgaccgagc attctatgga ctcaagcagg tggagagggc caatgaagcc ttggcgattg
     1081 acaccttgct catcagtgat gagctcttcc ggcatcagga tgtggccacc cggagccggt
     1141 atgtcaggct ggtggacagt gtgaaagaga atgcgggcac cgtaaggata ttctccagtc
     1201 tccacgtgtc tggggaacag cttggtcagc tgactggagt agctgccatt ctccgcttcc
     1261 ctgtgccgga actttctgac caagaggatg attcaagttc tgaagaggat taagacggaa
     1321 actcaatagt ttcttcttct acagcatcct tgacaagtgc aaggccgcac ttgttggtcc
     1381 tgctggggtt tcatgtgtga tgggttccca tgaagtgttt tatggtttgg ttggcaggac
     1441 atgtattcca attaaataaa ccacaacgat gtccaagcaa aaaaaaaaaa aaaaaaaaaa
     1501 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
//
