LOCUS       NM_001107259            3547 bp    mRNA    linear   ROD 22-MAR-2023
DEFINITION  Rattus norvegicus pellino E3 ubiquitin protein ligase family member
            2 (Peli2), mRNA.
ACCESSION   NM_001107259 XM_001062693 XM_223941
VERSION     NM_001107259.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3547)
  AUTHORS   Weber A, Wasiliew P and Kracht M.
  TITLE     Interleukin-1 (IL-1) pathway
  JOURNAL   Sci Signal 3 (105), cm1 (2010)
   PUBMED   20086235
  REMARK    Review article
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3547)
  AUTHORS   Dong W, Liu Y, Peng J, Chen L, Zou T, Xiao H, Liu Z, Li W, Bu Y and
            Qi Y.
  TITLE     The IRAK-1-BCL10-MALT1-TRAF6-TAK1 cascade mediates signaling to
            NF-kappaB from Toll-like receptor 4
  JOURNAL   J Biol Chem 281 (36), 26029-26040 (2006)
   PUBMED   16831874
REFERENCE   3  (bases 1 to 3547)
  AUTHORS   Jensen LE and Whitehead AS.
  TITLE     Pellino2 activates the mitogen activated protein kinase pathway
  JOURNAL   FEBS Lett 545 (2-3), 199-202 (2003)
   PUBMED   12804775
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH474040.1.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_001062693.1, XM_223941.4.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMEA5756307,
                              SAMEA5760383 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..3547
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="15"
                     /map="15p14"
     gene            1..3547
                     /gene="Peli2"
                     /gene_synonym="RGD1565884"
                     /note="pellino E3 ubiquitin protein ligase family member
                     2"
                     /db_xref="GeneID:305835"
                     /db_xref="RGD:1565884"
     exon            1..331
                     /gene="Peli2"
                     /gene_synonym="RGD1565884"
                     /inference="alignment:Splign:2.1.0"
     CDS             255..1514
                     /gene="Peli2"
                     /gene_synonym="RGD1565884"
                     /EC_number="2.3.2.27"
                     /note="protein pellino homolog 2; pellino 2"
                     /codon_start=1
                     /product="E3 ubiquitin-protein ligase pellino homolog 2"
                     /protein_id="NP_001100729.1"
                     /db_xref="GeneID:305835"
                     /db_xref="RGD:1565884"
                     /translation="MFSPGQEEPSSPNKEPVKYGELVVLGYNGALPNGDRGRRKSRFA
                     LYKRTKANGVKPSTIHVVSTPQASKAISCKGQHSISYTLSRNQTVVVEYTHDNDTDMF
                     QVGRSTESPIDFVVTDTVSGGQNDDAQITQSTISRFACRIVCDRNEPYTARIFAAGFD
                     SSKNIFLGEKAAKWKNPGGHMDGLTTNGVLVMHPRGGFTDESQPGVWREISVCGDVYT
                     LRETRSAQQRGKLVESETNVLQDGSLIDLCGATLLWRTADGLFHAPTQKHIEALRQEI
                     NAARPQCPVGLNTLAFPSINRKEVVEEKQPWAYLSCGHVHGYHSWGHRSDGEANEREC
                     PMCRTVGPYVPLWLGCEAGFYVDAGPPTHAFTPCGHVCSEKSAKYWSQIPLPHGTHAF
                     HAACPFCATQLVGEQNCIKLIFQGPVD"
     exon            332..461
                     /gene="Peli2"
                     /gene_synonym="RGD1565884"
                     /inference="alignment:Splign:2.1.0"
     exon            462..563
                     /gene="Peli2"
                     /gene_synonym="RGD1565884"
                     /inference="alignment:Splign:2.1.0"
     exon            564..758
                     /gene="Peli2"
                     /gene_synonym="RGD1565884"
                     /inference="alignment:Splign:2.1.0"
     exon            759..947
                     /gene="Peli2"
                     /gene_synonym="RGD1565884"
                     /inference="alignment:Splign:2.1.0"
     exon            948..3547
                     /gene="Peli2"
                     /gene_synonym="RGD1565884"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ggctccggtc gccgctcgca ttcctagtcc ggtcccgctc gcagcggcgg aagagcgtgt
       61 agctccgggg aagccggcgg gcgacgctcg cagccacgac ggagcagccg cgggactggc
      121 cgccccgcgc cccgttcgcc gccgtgccgt ttcccggcgc gctcaccccg ttctcgggat
      181 gggagtgtag cggcggcgcg gactcggcgg ggatcgcggc ggaggcggct gcggcggcgg
      241 ccgagcacgg ctccatgttt tcacccggcc aggaggaacc cagctccccc aacaaggagc
      301 cggtgaaata cggggagctg gtggtcctgg ggtacaatgg tgctttacct aatggtgaca
      361 ggggcaggag gaaaagcaga tttgccctgt ataagcggac caaggccaac ggtgtcaaac
      421 ccagcacaat ccacgtggtc tccacacccc aggcatccaa ggccatcagc tgcaaaggtc
      481 aacacagcat atcgtacact ttgtcacgga accagaccgt agtggtggag tacacacatg
      541 ataatgacac ggacatgttt caggtgggca ggtcaacaga aagtcccatc gacttcgtgg
      601 tcacagacac ggtttccggc ggtcagaacg acgatgccca gatcacacag agcaccatct
      661 ctaggtttgc ctgcaggatc gtgtgcgaca ggaacgagcc atacacagca cgcatattcg
      721 cagcagggtt cgattcttcc aaaaatatat tcctcggcga gaaggcggca aagtggaaaa
      781 accctggcgg gcacatggac ggactcacca ccaacggcgt cctggtaatg cacccaagag
      841 gaggcttcac ggatgagtcc cagcccggag tctggagaga gatctccgtc tgtggagacg
      901 tgtacacctt gagggagacc aggtcggccc agcagagggg gaagctggtg gaaagcgaga
      961 ccaatgtcct gcaagatggc tccctcattg acctgtgcgg ggccacgctc ctctggagaa
     1021 ccgccgacgg cctcttccac gcaccgactc agaagcacat tgaagccctc cggcaggaga
     1081 tcaacgcagc ccgaccccag tgtcccgtgg gcctcaacac cctggccttc cccagcatca
     1141 accggaagga agtggtagaa gagaagcagc cctgggcgta cctgagctgc ggtcacgtgc
     1201 acggctacca cagctggggc catcggagcg acggcgaagc caacgagcgg gagtgtccca
     1261 tgtgcaggac tgtgggcccc tatgtccccc tctggctggg ctgtgaggca gggttttatg
     1321 tcgatgcagg acctccaact cacgctttca ccccctgtgg gcacgtctgt tcggagaagt
     1381 ccgcaaagta ctggtcccag attccactgc cccacggaac ccacgcattt cacgccgcct
     1441 gtccgttctg tgccacgcag ctggttggtg aacaaaactg catcaaattg attttccaag
     1501 gtccagtgga ctgacaccct ggacgaccgt ctacatgacg ataacacgtt actgtgaaga
     1561 tttcgccact aactgtagat cctacctttt tgtaaggctc tttgttgagg ggacggcgga
     1621 ctgagttggg acgacagagg tggggcaggc gatgacagat accactgtgt ttggcatgcc
     1681 cagaacagca gcctcacctg aggtctgcct gactaaactt taatacctgt gtaatgatta
     1741 gatttcaact gccatgcttt tatttttaac tttaggtttt taaccagatt tttttccccc
     1801 tttgtaaact tgggtaagat tttacaaatg tagaagaagg gtactctgca gatgtctctt
     1861 agagcacagc ctgcagagct gtgtggcaca ggagtcacac atctggtgat gttcagtggt
     1921 tgggaatact tgacagtggc cagaatctga cccagtacca aagggccagc tctgttggcc
     1981 ctgccacaaa cacccgtgga caggaggcgt agaccatgca cttgtcttga actctgtagc
     2041 ttttcctcac tttttttttt tttttttttt ttttactttg ggtggaagag agaatccata
     2101 tactgtttca ttttaacttt agtggaattc acttacatat tcactcatca gatatgtggc
     2161 atgtcaaaca aagaaccccc ccccatggtc ctagcctgcc ctgttattaa ttttgcttag
     2221 cgtgacactt acatgtcaag aagtgattgg ttggttggtt aactgattga ttgatgattg
     2281 aattcatgaa ctgagggtgg cagcagcggg cgtgtcctag gtactctaac atcagtttta
     2341 tctgcacacc agaaaactta agacccaagt gggatttaaa atacgctttt acttctaaaa
     2401 ccacttgctg gcacgtcctg tgtttccttt ctcttcttct taggaaagcc caagattttt
     2461 taagcccaga agcaacaagc aacagcgaga ttgtcatttc tgtcccctac cttcccacca
     2521 tctgtcacct tccctcacag cttaaggaac cccataaggt ttttggtttt gttttttgtt
     2581 ttttgttttt tttaatgttt gcaaatcaag ctaaatctaa atgtgattgt cagctacacg
     2641 gagcactgag tggcatgtgt gtagagattg gtcgagattc ctgcttttga gagggcaagt
     2701 gagtgtttac tggggaatca ttaaatcagt ttcatatgag ctgcactgcc cctctctgtt
     2761 tcatcttgca ttgattgata atgcctgagt gcttgttttc tatgcttggt gacagtggta
     2821 tcagaggctc ccagaatgtc agcatggaga cacactgctg ggcttagctg cattccaccc
     2881 cattcccagg gagaaagtct tcggttaaat taacatctgc tcagagggac cgccaacaga
     2941 tctgatctgc ctgttttagc ttttgtaaat ataaataatt tatatgatta tgacatatcc
     3001 atacttgaat cggtttttcc atatcttgcc tattagcaga tatttcacct attttcaacc
     3061 aattaaacct atttgagtag tttttcctga aggcaaaacg gtaatattaa ttcctctgta
     3121 gtgttgctgc ttagttcgac tcaatttgct ggagttacct gtcattttaa aaatagcttt
     3181 attttccctt ggagactgtt aagaattatg agagagtttt ttgttttaat tatatttatt
     3241 aacgagataa aagtttacgt tataccacta aactctagtc cgaaacttac tacctcagct
     3301 gagaatcgag acaagagaga aagagagaga gagagagaaa gagagagaga gagagagaag
     3361 agaactttct agagaaacct agggtgccac ctggtgcagc cagcgttttt atcactggtt
     3421 ttcctcccca ccccacccca ccccgcctct agttatatgg aaatttatag tttgagggtt
     3481 cctgtcgtaa tcttgtaaga taaagggtct cacacccagt aaggttaaat tttatatttc
     3541 acccatc
//
