LOCUS       NM_001101805            7071 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus PDS5 cohesin associated factor B (Pds5b),
            transcript variant 2, mRNA.
ACCESSION   NM_001101805 XM_001056510 XM_001056563 XM_221833
VERSION     NM_001101805.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 7071)
  AUTHORS   Zhang,B., Chang,J., Fu,M., Huang,J., Kashyap,R., Salavaggione,E.,
            Jain,S., Kulkarni,S., Deardorff,M.A., Uzielli,M.L., Dorsett,D.,
            Beebe,D.C., Jay,P.Y., Heuckeroth,R.O., Krantz,I. and Milbrandt,J.
  TITLE     Dosage effects of cohesin regulatory factor PDS5 on mammalian
            development: implications for cohesinopathies
  JOURNAL   PLoS One 4 (5), e5232 (2009)
   PUBMED   19412548
  REMARK    Erratum:[PLoS One. 2009;4(5). doi:
            10.1371/annotation/ea5b7eb5-5087-448a-8325-c8efff1f54d9.
            Shashikant, Kulkarni [corrected to Kulkarni, Shashikant]]
REFERENCE   2  (bases 1 to 7071)
  AUTHORS   Watrin,E., Schleiffer,A., Tanaka,K., Eisenhaber,F., Nasmyth,K. and
            Peters,J.M.
  TITLE     Human Scc4 is required for cohesin binding to chromatin,
            sister-chromatid cohesion, and mitotic progression
  JOURNAL   Curr Biol 16 (9), 863-874 (2006)
   PUBMED   16682347
REFERENCE   3  (bases 1 to 7071)
  AUTHORS   Losada,A., Yokochi,T. and Hirano,T.
  TITLE     Functional contribution of Pds5 to cohesin-mediated cohesion in
            human cells and Xenopus egg extracts
  JOURNAL   J Cell Sci 118 (Pt 10), 2133-2141 (2005)
   PUBMED   15855230
REFERENCE   4  (bases 1 to 7071)
  AUTHORS   Geck,P., Maffini,M.V., Szelei,J., Sonnenschein,C. and Soto,A.M.
  TITLE     Androgen-induced proliferative quiescence in prostate cancer cells:
            the role of AS3 as its mediator
  JOURNAL   Proc Natl Acad Sci U S A 97 (18), 10185-10190 (2000)
   PUBMED   10963680
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000012.1 and CK357543.1.
            
            On or before Aug 22, 2007 this sequence version replaced
            XM_221833.4, XM_001056510.1, XM_001056563.1.
            
            Transcript Variant: This variant (2) lacks alternate in-frame
            segments in the 3' coding region, compared to variant 1. The
            resulting protein (isoform 2) is shorter when it is compared to
            isoform 1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            transcript and genomic sequence to make the sequence consistent
            with the reference genome assembly. The genomic coordinates used
            for the transcript record were based on alignments.
            
            ##Evidence-Data-START##
            RNAseq introns :: partial sample support SAMEA5760383, SAMEA5760386
                              [ECO:0000350]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-117               JAXUCZ010000012.1  5090942-5091058
            118-321             JAXUCZ010000012.1  5095030-5095233
            322-408             JAXUCZ010000012.1  5098282-5098368
            409-506             JAXUCZ010000012.1  5098463-5098560
            507-633             JAXUCZ010000012.1  5099570-5099696
            634-714             JAXUCZ010000012.1  5105175-5105255
            715-855             JAXUCZ010000012.1  5111969-5112109
            856-971             JAXUCZ010000012.1  5114700-5114815
            972-1066            JAXUCZ010000012.1  5118747-5118841
            1067-1212           JAXUCZ010000012.1  5122417-5122562
            1213-1364           JAXUCZ010000012.1  5123868-5124019
            1365-1971           CK357543.1         82-688
            1972-2132           JAXUCZ010000012.1  5144145-5144305
            2133-2256           JAXUCZ010000012.1  5150275-5150398
            2257-2415           JAXUCZ010000012.1  5152933-5153091
            2416-2484           JAXUCZ010000012.1  5153997-5154065
            2485-2621           JAXUCZ010000012.1  5155319-5155455
            2622-2745           JAXUCZ010000012.1  5157643-5157766
            2746-2950           JAXUCZ010000012.1  5162845-5163049
            2951-3065           JAXUCZ010000012.1  5164898-5165012
            3066-3198           JAXUCZ010000012.1  5166489-5166621
            3199-3318           JAXUCZ010000012.1  5166939-5167058
            3319-3381           JAXUCZ010000012.1  5167898-5167960
            3382-3531           JAXUCZ010000012.1  5168627-5168776
            3532-3968           JAXUCZ010000012.1  5173903-5174339
            3969-4076           JAXUCZ010000012.1  5174441-5174548
            4077-4215           JAXUCZ010000012.1  5176775-5176913
            4216-7071           JAXUCZ010000012.1  5178353-5181208
FEATURES             Location/Qualifiers
     source          1..7071
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="12"
                     /map="12p12"
     gene            1..7071
                     /gene="Pds5b"
                     /gene_synonym="Aprin; AS3; CG008"
                     /note="PDS5 cohesin associated factor B"
                     /db_xref="GeneID:304218"
                     /db_xref="RGD:1310838"
     exon            1..117
                     /gene="Pds5b"
                     /gene_synonym="Aprin; AS3; CG008"
                     /inference="alignment:Splign:2.1.0"
     CDS             10..4251
                     /gene="Pds5b"
                     /gene_synonym="Aprin; AS3; CG008"
                     /note="isoform 2 is encoded by transcript variant 2;
                     androgen-induced prostate proliferative shutoff associated
                     protein; sister chromatid cohesion protein PDS5 homolog B;
                     androgen-induced shutoff 3; androgen-induced prostate
                     proliferative shutoff-associated protein AS3; PDS5,
                     regulator of cohesion maintenance, homolog B"
                     /codon_start=1
                     /product="sister chromatid cohesion protein PDS5 homolog B
                     isoform 2"
                     /protein_id="NP_001095275.1"
                     /db_xref="GeneID:304218"
                     /db_xref="RGD:1310838"
                     /translation="MAHSKTRTNDGKITYPPGVKEISDKISKEEMVRRLKMVVKTFMD
                     MDQDSEEEKELYLNLALHLASDFFLKHPDKDVRLLVACCLADIFRIYAPEAPYTSPDK
                     LKDIFMFITRQLKGLEDTKSPQFNRYFYLLENIAWVKSYNICFELEDSNEIFTQLYRT
                     LFSVINNGHNQKVHMHMVDLMSSIICEGDTVSQELLDTVLVNLVPAHKNLNKQAYDLA
                     KALLKRTAQAIEPYITNFFNQVLMLGKTSISDLSEHVFDLILELYNIDSHLLLSVLPQ
                     LEFKLKSNDNEERLQVVKLLAKMFGAKDSELASQNKPLWQCYLGRFNDIHVPIRLECV
                     KFASHCLMNHPDLAKDLTEYLKVRSHDPEEAIRHDVIVSIVTAAKKDILLVNDHLLNF
                     VRERTLDKRWRVRKEAMMGLAQIYKKYALQSAAGKDAAKQICWVKDKLLHIYYQNSID
                     DRLLVERIFAQYMVPHNLETTERMKCLYYLYATLDLNAVKALNEMWKCQNLLRHQVKD
                     LLDLIKQPKTDASVKAIFSKVMVITRNLPDPGKAQDFMKKFTQVLEDDEKIRKQLEAL
                     VSPTCSCKQAEGCVREITKKLGNPKQPTNPFLEMIKFLLERIAPVHIDTESISALIKQ
                     VNKSIDGTADDEDEGVPTDQAIRAGLELLKVLSFTHPISFHSAETFESLLACLKMDDE
                     KVAEAALQIFKNTGSKIEEDFPHIRSALLPVLHHKSKKGPPRQAKYAIHCIHAIFSSK
                     ETQFAQIFEPLHKSLDPSNLEHLITPLVTIGHIALLAPDQFAAPLKSLVATFIVKDLL
                     MNDRLPGKKTTKLWVPDEEVSPETMVKIQAIKMMVRWLLGMKNNHSKSGTSTLRLLTT
                     ILHSDGDLTEQGKISKPDMSRLRLAAGSAIVKLAQEPCYHEIITLEQYQLCALAINDE
                     CYQVRQVFAQKLHKGLSRLRLPLEYMAICALCAKDPVKERRAHARQCLVKNITVRREY
                     LKQHAAVSEKLLSLLPEYVVPYTIHLLAHDPDYVKVQDIEQLKDVKECLWFVLEILMA
                     KNENNSHAFIRKMVENIKQTKDAQGPDDTKMNEKLYTVCDVAMNIIMSKSTTYSLESP
                     KDPVLPARFFTQPDKNFSNTKNYLPPEMKSFFTPGKPKTANVLGAVNKPLSSAGKQSQ
                     TKSSRMETVSNASSSSNPSSPGRIKGRQSELEKPRSRKKASVTDPEEKLGMDDLSKLV
                     QEQKPKGSQRGRKRGHAASESEEQQWPEEKRHKEELLGNEDEQNSPPKKGKRGRPPKP
                     LGGTSKEEPVVKTSKKGNKKKPAPPVVDEDEEEERQMGNTEQKSKSKQQRTSKRAQQR
                     AESPETSAVESTQSTPQKGRGRPSKTPSPSQPKKNIRVGRSKQVATKENDSSEEMDVL
                     QASSPVSDDTTQEGAEEEDISAGNVRRRSSKRERR"
     exon            118..321
                     /gene="Pds5b"
                     /gene_synonym="Aprin; AS3; CG008"
                     /inference="alignment:Splign:2.1.0"
     exon            322..408
                     /gene="Pds5b"
                     /gene_synonym="Aprin; AS3; CG008"
                     /inference="alignment:Splign:2.1.0"
     exon            409..506
                     /gene="Pds5b"
                     /gene_synonym="Aprin; AS3; CG008"
                     /inference="alignment:Splign:2.1.0"
     exon            507..633
                     /gene="Pds5b"
                     /gene_synonym="Aprin; AS3; CG008"
                     /inference="alignment:Splign:2.1.0"
     exon            634..714
                     /gene="Pds5b"
                     /gene_synonym="Aprin; AS3; CG008"
                     /inference="alignment:Splign:2.1.0"
     exon            715..855
                     /gene="Pds5b"
                     /gene_synonym="Aprin; AS3; CG008"
                     /inference="alignment:Splign:2.1.0"
     exon            856..971
                     /gene="Pds5b"
                     /gene_synonym="Aprin; AS3; CG008"
                     /inference="alignment:Splign:2.1.0"
     exon            972..1066
                     /gene="Pds5b"
                     /gene_synonym="Aprin; AS3; CG008"
                     /inference="alignment:Splign:2.1.0"
     exon            1067..1212
                     /gene="Pds5b"
                     /gene_synonym="Aprin; AS3; CG008"
                     /inference="alignment:Splign:2.1.0"
     exon            1213..1364
                     /gene="Pds5b"
                     /gene_synonym="Aprin; AS3; CG008"
                     /inference="alignment:Splign:2.1.0"
     exon            1365..1478
                     /gene="Pds5b"
                     /gene_synonym="Aprin; AS3; CG008"
                     /inference="alignment:Splign:2.1.0"
     exon            1479..1560
                     /gene="Pds5b"
                     /gene_synonym="Aprin; AS3; CG008"
                     /inference="alignment:Splign:2.1.0"
     exon            1561..1609
                     /gene="Pds5b"
                     /gene_synonym="Aprin; AS3; CG008"
                     /inference="alignment:Splign:2.1.0"
     exon            1610..1749
                     /gene="Pds5b"
                     /gene_synonym="Aprin; AS3; CG008"
                     /inference="alignment:Splign:2.1.0"
     exon            1750..1865
                     /gene="Pds5b"
                     /gene_synonym="Aprin; AS3; CG008"
                     /inference="alignment:Splign:2.1.0"
     exon            1866..1971
                     /gene="Pds5b"
                     /gene_synonym="Aprin; AS3; CG008"
                     /inference="alignment:Splign:2.1.0"
     exon            1972..2132
                     /gene="Pds5b"
                     /gene_synonym="Aprin; AS3; CG008"
                     /inference="alignment:Splign:2.1.0"
     exon            2133..2256
                     /gene="Pds5b"
                     /gene_synonym="Aprin; AS3; CG008"
                     /inference="alignment:Splign:2.1.0"
     exon            2257..2415
                     /gene="Pds5b"
                     /gene_synonym="Aprin; AS3; CG008"
                     /inference="alignment:Splign:2.1.0"
     exon            2416..2484
                     /gene="Pds5b"
                     /gene_synonym="Aprin; AS3; CG008"
                     /inference="alignment:Splign:2.1.0"
     exon            2485..2621
                     /gene="Pds5b"
                     /gene_synonym="Aprin; AS3; CG008"
                     /inference="alignment:Splign:2.1.0"
     exon            2622..2745
                     /gene="Pds5b"
                     /gene_synonym="Aprin; AS3; CG008"
                     /inference="alignment:Splign:2.1.0"
     exon            2746..2950
                     /gene="Pds5b"
                     /gene_synonym="Aprin; AS3; CG008"
                     /inference="alignment:Splign:2.1.0"
     exon            2951..3065
                     /gene="Pds5b"
                     /gene_synonym="Aprin; AS3; CG008"
                     /inference="alignment:Splign:2.1.0"
     exon            3066..3198
                     /gene="Pds5b"
                     /gene_synonym="Aprin; AS3; CG008"
                     /inference="alignment:Splign:2.1.0"
     exon            3199..3318
                     /gene="Pds5b"
                     /gene_synonym="Aprin; AS3; CG008"
                     /inference="alignment:Splign:2.1.0"
     exon            3319..3381
                     /gene="Pds5b"
                     /gene_synonym="Aprin; AS3; CG008"
                     /inference="alignment:Splign:2.1.0"
     exon            3382..3531
                     /gene="Pds5b"
                     /gene_synonym="Aprin; AS3; CG008"
                     /inference="alignment:Splign:2.1.0"
     exon            3532..3968
                     /gene="Pds5b"
                     /gene_synonym="Aprin; AS3; CG008"
                     /inference="alignment:Splign:2.1.0"
     exon            3969..4076
                     /gene="Pds5b"
                     /gene_synonym="Aprin; AS3; CG008"
                     /inference="alignment:Splign:2.1.0"
     exon            4077..4215
                     /gene="Pds5b"
                     /gene_synonym="Aprin; AS3; CG008"
                     /inference="alignment:Splign:2.1.0"
     exon            4216..7071
                     /gene="Pds5b"
                     /gene_synonym="Aprin; AS3; CG008"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 atttccatca tggctcattc aaagacaaga accaacgatg gcaaaattac ttaccctcct
       61 ggtgtcaagg agatctcaga taaaatctct aaagaggaga tggtgaggcg gctaaagatg
      121 gttgtaaaaa cattcatgga catggaccag gactctgaag aggaaaagga actgtatcta
      181 aacctagctt tacaccttgc ttctgacttc ttcctcaagc atcctgataa agatgtccgt
      241 ttactggtgg cttgctgcct tgctgatatt ttcaggattt acgctcctga ggctccttac
      301 acatctcccg ataaactaaa ggatatattt atgtttataa caaggcaatt gaagggactg
      361 gaggacacaa agagccctca attcaatagg tatttttatt tacttgagaa cattgcatgg
      421 gttaaatcat ataacatatg ctttgagtta gaagatagca atgaaatctt tactcaacta
      481 tacagaacat tattctcagt tataaacaat ggccacaatc agaaagttca catgcacatg
      541 gtggacctta tgagctctat catctgtgaa ggtgacacag tatcgcagga gctcctagat
      601 acagtcttag tgaatctggt gcctgctcat aagaacttaa acaagcaagc gtatgatttg
      661 gcaaaggcgt tgctgaagag gaccgctcaa gctattgaac cctatattac caattttttt
      721 aatcaggttc tgatgcttgg gaaaacatct atcagtgatt tgtctgagca tgtctttgat
      781 ttgatcttgg aactctacaa cattgacagc catttgctgc tttctgttct gccccagctt
      841 gagtttaaat taaagagcaa tgacaatgaa gaacgcctcc aggttgttaa actcctggca
      901 aaaatgtttg gggcaaagga ctcagaattg gcctctcaaa acaaaccact ctggcagtgc
      961 tacttgggca ggttcaatga catccatgtg ccaatacgcc tggaatgtgt gaagtttgcc
     1021 agccactgcc tcatgaacca tcccgattta gcaaaggatt taacagagta tcttaaagtg
     1081 aggtcacacg accctgaaga agctattaga catgatgtca ttgtgtctat agtaacagct
     1141 gctaaaaagg acattcttct tgtcaacgat cacctactca actttgtgag agagcgaacg
     1201 ttggacaaac ggtggagagt acgcaaagaa gccatgatgg gacttgccca gatttacaag
     1261 aaatacgctt tacagtcagc ggctggcaag gacgctgcca agcagatatg ctgggtcaag
     1321 gacaagctgc tgcatatata ctatcagaac agcattgatg accggttgct tgttgagcgg
     1381 atctttgctc agtacatggt tcctcacaac ttggaaacta cggagcggat gaagtgcttg
     1441 tactacttgt atgctaccct ggacctgaat gccgtgaagg cattgaatga aatgtggaaa
     1501 tgtcaaaatc tactccgaca tcaagtaaag gatttgcttg atttaattaa acaaccaaaa
     1561 acagatgcca gtgtcaaggc catattttct aaagtgatgg ttattacaag aaatttgcca
     1621 gatcctggta aggcccagga cttcatgaag aaattcacac aagtgttgga agatgatgag
     1681 aaaatacgga aacagctgga ggcccttgtt agccctacat gctcctgcaa gcaggctgaa
     1741 ggctgtgtgc gtgaaataac taagaagctg ggaaacccta aacagcctac gaaccccttc
     1801 ttggagatga tcaagttcct cctggagagg atagcccctg tgcacattga cactgagtct
     1861 atcagcgctc ttatcaagca ggtgaataag tcgatagatg ggacagcaga tgatgaggac
     1921 gagggcgtcc ccacagatca ggctatccgc gcgggcctcg agctgctgaa ggtgctgtct
     1981 tttacacacc ctatctcatt ccactctgcc gagacgtttg aatccctgct ggcttgtctg
     2041 aagatggatg atgaaaaggt ggcggaagct gccctacaaa ttttcaaaaa cacaggaagc
     2101 aaaatcgaag aggatttccc tcacatcaga tcagccttgc ttcctgtcct acatcacaaa
     2161 tccaaaaaag gaccacctcg tcaggccaag tacgccatcc actgcattca tgccatattt
     2221 tccagtaaag agacccagtt tgcacagata tttgagcctc tgcataaaag cctggacccc
     2281 agcaacctgg agcacctgat caccccgctg gtcaccattg gtcacatcgc tctgctcgcg
     2341 cctgatcagt tcgctgcccc actcaagtcc ttggtagcaa ctttcattgt gaaggacctt
     2401 ctcatgaacg atcggcttcc aggaaaaaag acaactaagc tttgggttcc tgatgaagaa
     2461 gtctcccctg agacaatggt caaaattcag gctattaaga tgatggttcg ctggctgctc
     2521 ggaatgaaaa ataatcacag taaatcagga acttccaccc tcagattact aactacgata
     2581 ctgcatagtg atggggactt gacagaacaa gggaaaatta gtaaaccgga catgtcccgc
     2641 ctgagacttg ctgctgggag tgctattgtg aagctggcgc aagagccctg ttaccacgag
     2701 atcatcacac tggagcagta ccagctgtgc gcactggcca tcaatgacga gtgctatcaa
     2761 gtcaggcagg tgtttgctca gaaacttcac aaaggcctct cccgcttacg gctcccacta
     2821 gagtacatgg ccatctgtgc tctctgtgcc aaagacccgg tgaaagagcg gagagcgcat
     2881 gccaggcagt gcctggtgaa gaacatcact gtgaggaggg agtacctgaa gcagcacgcg
     2941 gctgttagtg aaaaattatt gtctcttctc ccagagtatg ttgttccgta tacaattcac
     3001 cttttggcac atgaccccga ctatgtcaaa gtgcaggata ttgaacaact taaagatgtg
     3061 aaagaatgcc tttggtttgt tctggagata ttgatggcta aaaatgaaaa caacagccat
     3121 gcatttatca gaaagatggt agaaaatatt aaacagacaa aagatgctca aggaccagat
     3181 gatacaaaaa tgaatgaaaa attgtacacc gtgtgtgatg tagccatgaa catcatcatg
     3241 tcaaagagca ccacatacag tctggagtcc ccaaaagacc cagtgttgcc tgctcggttt
     3301 ttcacccagc ctgacaagaa ttttagtaac accaaaaatt acctgcctcc agaaatgaaa
     3361 tcatttttca ctcctggaaa acctaaaaca gccaatgtcc tcggagcagt taataagccg
     3421 ctttcatcgg caggcaaaca gtctcagacc aaatcctcac ggatggaaac cgtgagcaac
     3481 gcgagcagca gctcaaaccc aagctctcct ggaagaataa aggggaggca atctgagttg
     3541 gagaagccta gaagtcggaa aaaagcatct gtcacagacc cagaagagaa attaggtatg
     3601 gatgacctta gtaagctggt ccaggaacag aaacctaaag gcagtcagcg gggccggaaa
     3661 agaggccatg cggcttcaga atcagaggag cagcagtggc ctgaggagaa gaggcacaaa
     3721 gaggagctcc tgggaaatga ggacgagcag aacagccccc cgaagaaggg caagagaggc
     3781 aggccaccaa agcctcttgg ggggacatcc aaggaagagc cagtggtgaa aacatccaag
     3841 aagggaaaca agaagaagcc tgcacctcct gtagtagacg aagatgaaga agaagaaaga
     3901 caaatgggaa acacagaaca gaagtcaaag agcaaacagc agcgcacgtc caagagggct
     3961 cagcagagag cagaatctcc tgagactagt gcagttgaat ccacacagtc cacaccacag
     4021 aaaggacggg gaagaccatc aaaaacgcca tcaccatcac aacccaaaaa aaatatccgt
     4081 gtaggacgct ccaaacaggt agctactaaa gaaaacgatt caagtgaaga aatggatgtg
     4141 cttcaggcca gctctcctgt cagcgacgac actacgcagg aaggagcaga agaggaggat
     4201 atttctgcag gaaatgtacg gcggcgaagc tccaaacgag agagacgatg aacatgccat
     4261 taactttctt tatgaaagct ttgggaaaaa aataacattt ttttgtcaag tatgaggcta
     4321 aataaagccc ttgatgcaca aaacgggact gccaaagtgt ggacagttgg acttttgatg
     4381 accatgaatt tgtggtcaca tgcatcagcc attcacagag tgatgacatt gactccagag
     4441 tcttgtgaaa gtgtcatgtg tgacggctgt gtaggcataa actaaagaga agcgtgtaaa
     4501 tagtcccact ccccatctct gacttctaaa gtgcttgtat agcttttatc tacggcttta
     4561 aactgacagt acccagctgc ttactggatc tattaatttg aaaagcattt gctagggtgg
     4621 atcttaagca gcagtctgtc agtgtttata ttggaattct ctgcaatttt actgtgaaaa
     4681 cttgttttca acaattggtg tcattttctt gatgtcacta cttgttggag ttaagtggtc
     4741 tcttcctgcc ccttcacagc tcatctgtgt gtactccagg gcacccgtca tctccgagtg
     4801 ctaagcctct gtcgccagcg ctaatgcctc tgtttggggc actgcacggg gcgggagata
     4861 gtcctgaact tacctgatga ctttacacct cagtattgct cccagaattt tctggccttt
     4921 catggcaatg aaaattttaa gaaagagatt taaaatattt taattttaaa gagtgtgtta
     4981 taaaataatg tactaaattc tttattccat tctatcatct tttttcagtt tatattaatc
     5041 tactgtatca ataaaattct gtaatttgaa tgggctttta atagtctaga atgttattgt
     5101 gtatagatat tcttgaacat tatgttcaga aatgcaaatt attacactat aatataaaat
     5161 ctgatatata cacattagga aagttctcat tctctataac catgtaaagt taatcagaaa
     5221 caaaaaattt tattgatgca gtgtatcttt ataaatctgt tcttgaaagc caagtgtttt
     5281 gtattttata gtgagttgca tgtttatgaa aaaattgctg atcatgagat gtgcttttct
     5341 gtaaattcat acttagccat agtatatgat agatgacccc ttaacatagt ttttcatcaa
     5401 gagtttataa ttgtacttta ttttggagcc aaaaaaattg tttttggggg aggggctggg
     5461 tggcagtgat ttatctagtt tgggctgaga ctttaggcgt cacactcaca aacgctgaga
     5521 ctcccactgc gtccagaaca ggagaagtgg acacttgcct gggtttaatt tagaggtctg
     5581 cagagtctaa aaatggatca tcgaggaggc tcacagcgcc ctttacatag agtgtgagct
     5641 gaaatgtatt gggtgccacc ttatgctccc ctgaattaac tttaggtttc tgggtgcagg
     5701 gttgtttttg cacagttgtt aacaatagaa aagaaagtta cattctgcgc taccgagttt
     5761 actataccaa gtagcagcag tttcacacag tacgcctttg tgtttaaggt gtgtttccaa
     5821 aactgaatat aatcaattgg gatgctatac agaagtgact attttagaaa tgacatcgtg
     5881 ctattttcta gtatgtattg cagatgatgt gattattttt ctttttaata tttcctcatg
     5941 tttatgaaac actttatttt taaaaagatg tttgaattgt gtcttaatct ttcagtgttt
     6001 aacttcattt gcaacagtgt tggcaccagt ggtgatggga ggcgctgtct gtcaggacag
     6061 ctaatgctgg attaggacac tttgagtttt aaatgtttca ttagctcagc tctccaaaca
     6121 atgatgtttc catctcagca gtacagaagc atgtttttaa atttatggca aaaataataa
     6181 aggatagcac tgtatttttg tcgttaacaa cttcattgga aatatttatg gaaacatgtt
     6241 caaaaccatt ttataagaca tacgaaatta ttatggagga tttttatttg catgatcata
     6301 gttcaccaga tttcactgca cattaatgct gtgcatcagt tcatggcaaa catggtcatc
     6361 gtagactttg tgttcaatgc cagtgagtct gtaattctac agcccacccg ttcacctttt
     6421 ggaaggacta taatgtaaaa tttccatttc ttgtgtagag aaataggtgc aataatgatc
     6481 aagtttttat gtcctgagtc tccgtcctgg gagcttcttc ttatgttaaa cttaacacgt
     6541 catgtactaa catctggaga gccacatact ttaaagtaaa ttaaagtaaa gctaagtatg
     6601 tgtccagcat ctgtgccgac agccgttagc acacgctgct gcggccatgc tcttttgagc
     6661 tgtatagctc attgtaacag acgccctggc ggatctgatg actcccgggt gagcctcgct
     6721 tgctgcagtg ccacactaag ctctcccagt gatccccact gtgtgtgtaa atgagaaatg
     6781 tgctgtaaaa cttgttctag acattaaagt ttaaatgact ttctacatct tcctacagct
     6841 tgcaagtttg acttttaagg ttccctttgc ctcctcgaag gatatcgggg atgtgatgat
     6901 ttgtttaact taggcataac tccactgcat agtgttatgt taccataacg aacagttggt
     6961 tctagatgac aagtttccag acacagtttt ggattttctg tgaacttaaa taaacgtaga
     7021 agctcatgta attatattcc tatgtgactc aatatatatt taccagagaa a
//
