LOCUS       NM_001107430            2847 bp    mRNA    linear   ROD 19-SEP-2024
DEFINITION  Rattus norvegicus pyruvate dehydrogenase phosphatase regulatory
            subunit (Pdpr), mRNA; nuclear gene for mitochondrial product.
ACCESSION   NM_001107430 XM_001075729 XM_001075755 XM_226475
VERSION     NM_001107430.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2847)
  AUTHORS   Morgenstern,M., Peikert,C.D., Lubbert,P., Suppanz,I., Klemm,C.,
            Alka,O., Steiert,C., Naumenko,N., Schendzielorz,A., Melchionda,L.,
            Muhlhauser,W.W.D., Knapp,B., Busch,J.D., Stiller,S.B.,
            Dannenmaier,S., Lindau,C., Licheva,M., Eickhorst,C., Galbusera,R.,
            Zerbes,R.M., Ryan,M.T., Kraft,C., Kozjak-Pavlovic,V., Drepper,F.,
            Dennerlein,S., Oeljeklaus,S., Pfanner,N., Wiedemann,N. and
            Warscheid,B.
  TITLE     Quantitative high-confidence human mitochondrial proteome and its
            dynamics in cellular context
  JOURNAL   Cell Metab 33 (12), 2464-2483 (2021)
   PUBMED   34800366
REFERENCE   2  (bases 1 to 2847)
  AUTHORS   Huang,B., Gudi,R., Wu,P., Harris,R.A., Hamilton,J. and Popov,K.M.
  TITLE     Isoenzymes of pyruvate dehydrogenase phosphatase. DNA-derived amino
            acid sequences, expression, and regulation
  JOURNAL   J Biol Chem 273 (28), 17680-17688 (1998)
   PUBMED   9651365
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473972.1.
            
            [WARNING] On Nov 12, 2024 this sequence was replaced by
            NM_001107430.2.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_226475.4, XM_001075755.1, XM_001075729.1.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMD00132261,
                              SAMD00132263 [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..2847
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="19"
                     /map="19q12"
     gene            1..2847
                     /gene="Pdpr"
                     /gene_synonym="RGD1308307"
                     /note="pyruvate dehydrogenase phosphatase regulatory
                     subunit"
                     /db_xref="GeneID:307852"
                     /db_xref="RGD:1308307"
     exon            1..274
                     /gene="Pdpr"
                     /gene_synonym="RGD1308307"
                     /inference="alignment:Splign:2.1.0"
     CDS             51..2687
                     /gene="Pdpr"
                     /gene_synonym="RGD1308307"
                     /EC_number="1.5.8.4"
                     /codon_start=1
                     /product="pyruvate dehydrogenase phosphatase regulatory
                     subunit, mitochondrial"
                     /protein_id="NP_001100900.1"
                     /db_xref="GeneID:307852"
                     /db_xref="RGD:1308307"
                     /translation="MLYRLLSIVQRQRTSPGWQTWSSARSSTSAAEAQSIALPAQAQV
                     VICGGGIMGTSVAYHLSKMGWQDIVLLEQGRLAAGSTRFCAGILSTARHSSIEQKMAD
                     YSNKLYHQLEQETGIQTGYLRTGSISLAQTQDRLISLKRINSRLNVVGIPSEIISPKK
                     VAELHPLLNVHDLVGAMHVPEDAVVSSADVALALASAASQNGVQIYDRTSVLHVLTKK
                     GRVTGVDTDKGQIECQYFVNCAGQWAYELGLSSEEPVSIPLHACEHFYLLTRPCDAPL
                     QSSTPTVVDADGRIYIRNWQGGVLSGGFEKNPKPIFTEGKNQLEIQNLREDWDHFEPL
                     LSSLLRRMPGLESVEILKLVNCPETFTADMKCIMGESPVVQGYFVLAGMNSAGLSLGG
                     GAGKLLAEWMVYGYPSENVWELDLQRFGALQGSRTFLRHRVMEVMPLIYDLKVPRWDF
                     QTGRQLRTSPLYDRLDAQGARWMEKHGFERPKYFVPPNKDLLALEQSKTFYKPDWFDI
                     VESEVKCCKEAVCVIDMSSFTKFEITSTGDQALESLQYLFSNDLDVPVGHIVHTGMLN
                     EYGGHENDCSIARLTKRSFFMISPTDQQVHCWAWLHKYLPKDSNLLLEDVTWKYTALN
                     LIGPRAVDVLSELSYAPMTPDHFPTLFCKEMSVGYANGIRVMSMTHTGEPGFMLYIPI
                     EYALHVYNEVMSVGQKYGIRNAGYYALRSLRIEKFFAFWGQDLNTLTTPLECGGESRV
                     KLEKGIDFIGRDALLQQKQTGVYKRLVMFILDDHDTDLDLWPWWGEPIYRNGKYAGKT
                     TSSAYSYTLERHVCLGYVHNFSEDSGEEQVVTADFINRGEYEIDIAGHRFQAKAKLYP
                     VTSFFTHKRRKDDVELSDFHGK"
     exon            275..408
                     /gene="Pdpr"
                     /gene_synonym="RGD1308307"
                     /inference="alignment:Splign:2.1.0"
     exon            409..490
                     /gene="Pdpr"
                     /gene_synonym="RGD1308307"
                     /inference="alignment:Splign:2.1.0"
     exon            491..654
                     /gene="Pdpr"
                     /gene_synonym="RGD1308307"
                     /inference="alignment:Splign:2.1.0"
     exon            655..776
                     /gene="Pdpr"
                     /gene_synonym="RGD1308307"
                     /inference="alignment:Splign:2.1.0"
     exon            777..894
                     /gene="Pdpr"
                     /gene_synonym="RGD1308307"
                     /inference="alignment:Splign:2.1.0"
     exon            895..1044
                     /gene="Pdpr"
                     /gene_synonym="RGD1308307"
                     /inference="alignment:Splign:2.1.0"
     exon            1045..1237
                     /gene="Pdpr"
                     /gene_synonym="RGD1308307"
                     /inference="alignment:Splign:2.1.0"
     exon            1238..1362
                     /gene="Pdpr"
                     /gene_synonym="RGD1308307"
                     /inference="alignment:Splign:2.1.0"
     exon            1363..1518
                     /gene="Pdpr"
                     /gene_synonym="RGD1308307"
                     /inference="alignment:Splign:2.1.0"
     exon            1519..1652
                     /gene="Pdpr"
                     /gene_synonym="RGD1308307"
                     /inference="alignment:Splign:2.1.0"
     exon            1653..1801
                     /gene="Pdpr"
                     /gene_synonym="RGD1308307"
                     /inference="alignment:Splign:2.1.0"
     exon            1802..1914
                     /gene="Pdpr"
                     /gene_synonym="RGD1308307"
                     /inference="alignment:Splign:2.1.0"
     exon            1915..2009
                     /gene="Pdpr"
                     /gene_synonym="RGD1308307"
                     /inference="alignment:Splign:2.1.0"
     exon            2010..2099
                     /gene="Pdpr"
                     /gene_synonym="RGD1308307"
                     /inference="alignment:Splign:2.1.0"
     exon            2100..2282
                     /gene="Pdpr"
                     /gene_synonym="RGD1308307"
                     /inference="alignment:Splign:2.1.0"
     exon            2283..2847
                     /gene="Pdpr"
                     /gene_synonym="RGD1308307"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ttgtattttt ggatcttagc tgagtgaaaa catatatctt ccaggtggtg atgctttacc
       61 ggttgctgtc tattgtccaa agacaaagaa ctagcccagg atggcagacc tggtcatcgg
      121 caagaagcag cacgtccgct gccgaggcgc agtctattgc tctgcctgcc caggcccagg
      181 tggtcatctg tgggggtgga atcatgggta cgtctgtggc ctatcacctc tccaaaatgg
      241 gatggcaaga tattgtcctt ttggagcagg gcaggctggc tgctggctca acaaggttct
      301 gtgctggcat cctaagcact gctaggcatt caagcattga acagaagatg gctgactatt
      361 caaacaaact ctaccatcag ttagaacaag aaacagggat tcaaacaggt tacttaagga
      421 caggctcaat ctctctggcc caaactcagg accggttgat ctctctgaag cgtatcaact
      481 caaggctgaa tgttgtaggt ataccttctg agatcatctc cccgaagaaa gtggccgaac
      541 ttcatcctct cctcaatgtg catgatctgg tgggagccat gcacgttcct gaggacgcag
      601 tagtgtcctc tgctgatgtg gctcttgccc tggcaagtgc tgcctcccag aatggtgttc
      661 agatttatga ccggacaagt gttcttcatg tactgaccaa aaaaggtcga gttactggtg
      721 tggacacaga taaagggcag atcgaatgcc agtattttgt caactgtgct ggtcagtggg
      781 cgtatgagct gggtttgtcc agcgaggagc cggttagtat cccgctgcac gcctgtgagc
      841 acttctacct tctgactcgt ccctgcgacg cccctctgca gagcagcaca ccaaccgttg
      901 tggatgcgga cggaagaatt tacattagga actggcaggg tggcgtcttg tctggaggct
      961 ttgagaagaa cccaaaacct attttcactg aaggcaagaa ccagttggaa attcagaacc
     1021 ttcgggaaga ttgggatcac tttgagcccc tgttgagttc cctcctgcgc aggatgccag
     1081 gattggagtc tgtggagatt ttgaagttgg tgaattgccc tgagaccttc acggcagaca
     1141 tgaagtgcat catgggcgag tcccctgtcg tccagggcta ctttgtcctg gcagggatga
     1201 actctgctgg cctgtcgctg ggcggaggag ctggaaagct cctagctgaa tggatggtgt
     1261 atggttaccc ctctgaaaac gtctgggaat tggacttgca gcgctttgga gccctccagg
     1321 gcagccgcac ctttctgcgc caccgggtca tggaagttat gcctctgata tacgatctga
     1381 aggttcctcg ttgggatttc cagactggaa ggcagttgcg cacatctcct ctttatgacc
     1441 ggctggatgc tcaaggagcc agatggatgg agaaacatgg atttgagagg ccaaagtact
     1501 ttgttccacc caacaaggac cttcttgcat tagaacagag caagactttc tacaagccag
     1561 actggtttga tattgtggag tctgaagtca aatgctgtaa ggaagctgtg tgtgtcattg
     1621 acatgtcttc tttcacaaaa tttgaaataa cttccactgg ggaccaggca ttagaaagtc
     1681 tgcagtacct tttctccaat gacctagatg tgcctgtagg ccacattgtt cacactggca
     1741 tgctcaatga atatggaggg cacgaaaatg actgcagcat tgctcgcctg accaaacgca
     1801 gtttcttcat gatctctcca actgatcagc aggtccactg ttgggcctgg cttcacaagt
     1861 acttgccgaa agacagcaac ttgctgctgg aagacgtcac ctggaagtac acagccctca
     1921 atctgattgg ccctcgagct gtggacgtgc tgtctgagtt gtcctatgcc cctatgactc
     1981 cagaccactt tccaactctc ttttgcaagg agatgagtgt gggctatgca aatgggatcc
     2041 gggtgatgag tatgactcac acaggagaac caggattcat gctgtatatc cccatagagt
     2101 atgctctgca tgtctacaat gaggtgatga gtgttggaca gaaatatgga atccggaatg
     2161 ctgggtatta cgctctcaga agtctccgaa ttgagaagtt ttttgctttc tggggtcagg
     2221 acttaaacac cctcaccacg cccctggaat gtggaggaga gtctcgcgtg aagttagaga
     2281 agggcataga cttcatcggt cgggatgccc tgctgcagca aaagcagacc ggggtatata
     2341 aacgcctcgt tatgtttatt ctggatgacc atgacacaga cctggacttg tggccttggt
     2401 ggggagaacc catttaccgg aacggaaagt acgctggcaa gaccaccagc agtgcctaca
     2461 gctacactct tgagcgccat gtatgcctgg gctatgtaca caacttttct gaggacagcg
     2521 gggaagagca ggtggtgaca gcagatttca tcaaccgagg agaatatgag attgacattg
     2581 caggacatcg gtttcaggcc aaggccaagc tctaccccgt cacctctttt ttcactcaca
     2641 agcgtagaaa ggatgacgtg gagctgagtg actttcatgg gaagtaatgc aagacttttt
     2701 cccttcctcc catcctctca ccatgaggag catcgttctg ggagctgacc tttcctctgt
     2761 ccctgtctcc tcactgaaga aggtactttg tcctctccta gtttttctgt ttgacctaaa
     2821 cccttttcct tgaaagcctg tcttccc
//
