LOCUS       NM_053650               1595 bp    mRNA    linear   ROD 29-MAR-2024
DEFINITION  Rattus norvegicus PDZ and LIM domain 3 (Pdlim3), mRNA.
ACCESSION   NM_053650
VERSION     NM_053650.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1595)
  AUTHORS   Pashmforoush,M., Pomies,P., Peterson,K.L., Kubalak,S., Ross,J. Jr.,
            Hefti,A., Aebi,U., Beckerle,M.C. and Chien,K.R.
  TITLE     Adult mice deficient in actinin-associated LIM-domain protein
            reveal a developmental pathway for right ventricular cardiomyopathy
  JOURNAL   Nat Med 7 (5), 591-597 (2001)
   PUBMED   11329061
REFERENCE   2  (bases 1 to 1595)
  AUTHORS   Jo,K., Rutten,B., Bunn,R.C. and Bredt,D.S.
  TITLE     Actinin-associated LIM protein-deficient mice maintain normal
            development and structure of skeletal muscle
  JOURNAL   Mol Cell Biol 21 (5), 1682-1687 (2001)
   PUBMED   11238905
REFERENCE   3  (bases 1 to 1595)
  AUTHORS   Xia,H., Winokur,S.T., Kuo,W.L., Altherr,M.R. and Bredt,D.S.
  TITLE     Actinin-associated LIM protein: identification of a domain
            interaction between PDZ and spectrin-like repeat motifs
  JOURNAL   J Cell Biol 139 (2), 507-515 (1997)
   PUBMED   9334352
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000016.1.
            
            On Dec 2, 2020 this sequence version replaced NM_053650.1.
            
            Sequence Note: This sequence has been modified as follows: removed
            18 bp suspected to be vector contamination from the 5' end.
            
            ##Evidence-Data-START##
            Transcript exon combination :: FQ215471.1, AF002281.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760386,
                                           SAMEA5760475 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-189               JAXUCZ010000016.1  53116029-53116217   c
            190-341             JAXUCZ010000016.1  53105129-53105280   c
            342-426             JAXUCZ010000016.1  53103919-53104003   c
            427-494             JAXUCZ010000016.1  53095336-53095403   c
            495-758             JAXUCZ010000016.1  53090802-53091065   c
            759-889             JAXUCZ010000016.1  53089222-53089352   c
            890-1001            JAXUCZ010000016.1  53086787-53086898   c
            1002-1595           JAXUCZ010000016.1  53085020-53085613   c
FEATURES             Location/Qualifiers
     source          1..1595
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="16"
                     /map="16q11"
     gene            1..1595
                     /gene="Pdlim3"
                     /gene_synonym="Actn2lp; Alp"
                     /note="PDZ and LIM domain 3"
                     /db_xref="GeneID:114108"
                     /db_xref="RGD:620427"
     exon            1..189
                     /gene="Pdlim3"
                     /gene_synonym="Actn2lp; Alp"
                     /inference="alignment:Splign:2.1.0"
     CDS             97..1191
                     /gene="Pdlim3"
                     /gene_synonym="Actn2lp; Alp"
                     /note="SK-2; actinin-associated LIM protein;
                     alpha-actinin-2-associated LIM protein; actinin alpha 2
                     associated LIM protein"
                     /codon_start=1
                     /product="PDZ and LIM domain protein 3"
                     /protein_id="NP_446102.2"
                     /db_xref="GeneID:114108"
                     /db_xref="RGD:620427"
                     /translation="MPQNVVLPGPAPWGFRLSGGIDFNQPLVITRITPGSKAEAANLC
                     PGDVILAIDGFGTESMTHADAQDRIKAASYQLCLKIDRAETRLWSPQVSEDGKAHPFK
                     INLEAEPQDVNYFEHKHNIRPKPFIIPGRTSGCSTPSGIDCGSGRSTPSSVSTVSTIC
                     PGDLKVAAKMAPNIPLEMELPGVKIVHAQFNTPMQLYSDDNIMETLQGQVSTALGETP
                     SMSEPTASVPPQSDVYRMLHDNRDEPAAPRQSGSFRVLQELVNDGSDDRPAGTRSVRA
                     PVTKVHGGAGGAQRMPLCDKCGSGIVGAVVKARDKYRHPECFVCADCNLNLKQKGYFF
                     VEGELYCEMHARARTRPPEGYDTVTLYPKA"
     exon            190..341
                     /gene="Pdlim3"
                     /gene_synonym="Actn2lp; Alp"
                     /inference="alignment:Splign:2.1.0"
     exon            342..426
                     /gene="Pdlim3"
                     /gene_synonym="Actn2lp; Alp"
                     /inference="alignment:Splign:2.1.0"
     exon            427..494
                     /gene="Pdlim3"
                     /gene_synonym="Actn2lp; Alp"
                     /inference="alignment:Splign:2.1.0"
     exon            495..758
                     /gene="Pdlim3"
                     /gene_synonym="Actn2lp; Alp"
                     /inference="alignment:Splign:2.1.0"
     exon            759..889
                     /gene="Pdlim3"
                     /gene_synonym="Actn2lp; Alp"
                     /inference="alignment:Splign:2.1.0"
     exon            890..1001
                     /gene="Pdlim3"
                     /gene_synonym="Actn2lp; Alp"
                     /inference="alignment:Splign:2.1.0"
     exon            1002..1595
                     /gene="Pdlim3"
                     /gene_synonym="Actn2lp; Alp"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 aggttgcagc ccccgggaac taagtgggtt gtccgggttc cgagactagc gctctgcaga
       61 gacaccgatc gctggaccct ctcacaggaa ggcgtcatgc cccaaaacgt agttctcccg
      121 ggccctgcgc cctggggctt cagactctca ggaggcatag acttcaacca gcctttggtc
      181 atcaccagga tcactccggg aagcaaggca gaagccgcca acctgtgccc tggagacgtc
      241 atcctggcta tcgatggctt tggtacggag tccatgactc atgctgatgc tcaggacagg
      301 atcaaagcag catcttacca gttgtgtctc aagattgaca gggcagaaac tcgcttatgg
      361 tccccgcagg tgtcggaaga tgggaaagcg catcccttta aaatcaacct agaggctgaa
      421 ccgcaggatg tgaactactt tgaacacaag cacaatattc ggcccaaacc tttcataatt
      481 ccaggccgaa ccagtggctg cagcactcct tccggtattg actgtggcag tggacgtagc
      541 accccttctt ccgtcagtac cgttagtacg atctgcccag gtgacttgaa agttgctgct
      601 aagatggccc ctaacattcc tttggaaatg gaacttccgg gcgtgaagat tgtacatgct
      661 cagtttaaca ctcctatgca gttgtactca gatgacaata ttatggaaac acttcagggt
      721 caggtttcca cagctctagg ggagacaccc tccatgagtg aacccacagc ttcagttccc
      781 cctcagtcgg acgtgtaccg aatgctgcac gacaatcggg atgaaccagc tgctcctcgc
      841 cagtcaggct ccttcagggt cctgcaggag ctggtgaacg acgggtctga tgaccgtcct
      901 gctggaactc gaagtgtgag ggctccggtt actaaagtcc atggcggggc tggcggtgcc
      961 cagaggatgc cactctgtga caagtgtggc agtggtattg taggtgctgt ggtcaaggcc
     1021 cgggataagt accggcaccc cgagtgcttt gtgtgtgctg actgtaacct caacctcaag
     1081 cagaaaggtt acttcttcgt ggagggggag ctgtattgtg agatgcacgc aagagcccgc
     1141 acgaggcccc cagaaggcta cgacaccgtc actctgtacc ccaaagctta aattctttac
     1201 agacgagaac actcattcac gcatgcgcac acacgaacac cggcggatga taaggaggac
     1261 ttcaagcagg aggagtgcga aaggtcacct cccaatcgaa agccgaggct tttagtcatt
     1321 tatcttactg tgtagtgagg gaaagacatg gggaggcaga ggcctgccta ctgacaaaag
     1381 tattatctgt gggttgtaat tctttatctt tggggacagc aatggtgaca tttaaagcaa
     1441 taacgttgta ataccatgct ctacggtttc catctgttac acgcccatcc gatgcgtgaa
     1501 cacctggata tgtagggggg tccacttgtc tttccttcca agttgctttt ggtaattgta
     1561 gtaacgccaa attacagctt tgtactggaa caaaa
//
