LOCUS       NM_017365               1391 bp    mRNA    linear   ROD 05-JUN-2024
DEFINITION  Rattus norvegicus PDZ and LIM domain 1 (Pdlim1), mRNA.
ACCESSION   NM_017365
VERSION     NM_017365.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1391)
  AUTHORS   Yan,Y., Qin,X., Zheng,Y., Jin,T., Hu,Y., An,Q. and Leng,B.
  TITLE     Decreased PDLIM1 expression in endothelial cells contributes to the
            development of intracranial aneurysm
  JOURNAL   Vasc Med 29 (1), 5-16 (2024)
   PUBMED   38334094
  REMARK    GeneRIF: Decreased PDLIM1 expression in endothelial cells
            contributes to the development of intracranial aneurysm.
REFERENCE   2  (bases 1 to 1391)
  AUTHORS   Guo,Z., Neilson,L.J., Zhong,H., Murray,P.S., Zanivan,S. and
            Zaidel-Bar,R.
  TITLE     E-cadherin interactome complexity and robustness resolved by
            quantitative proteomics
  JOURNAL   Sci Signal 7 (354), rs7 (2014)
   PUBMED   25468996
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 1391)
  AUTHORS   Miyazaki,K., Ohno,K., Tamura,N., Sasaki,T. and Sato,K.
  TITLE     CLP36 and RIL recruit alpha-actinin-1 to stress fibers and
            differentially regulate stress fiber dynamics in F2408 fibroblasts
  JOURNAL   Exp Cell Res 318 (14), 1716-1725 (2012)
   PUBMED   22659164
  REMARK    GeneRIF: The CLP36 has a redundant role in the formation of stress
            fibers, but have different effects on stress fiber dynamics in
            F2408 cells.
REFERENCE   4  (bases 1 to 1391)
  AUTHORS   Kuo,J.C., Han,X., Hsiao,C.T., Yates,J.R. 3rd and Waterman,C.M.
  TITLE     Analysis of the myosin-II-responsive focal adhesion proteome
            reveals a role for beta-Pix in negative regulation of focal
            adhesion maturation
  JOURNAL   Nat Cell Biol 13 (4), 383-393 (2011)
   PUBMED   21423176
REFERENCE   5  (bases 1 to 1391)
  AUTHORS   Tamura,N., Ohno,K., Miyazaki,K., Sato,K., Tamura,N. and Kanayama,N.
  TITLE     Expression of stress fiber-associated protein CLP36 during
            differentiation of Rcho-1 trophoblast giant cells
  JOURNAL   Placenta 31 (8), 743-745 (2010)
   PUBMED   20599268
  REMARK    GeneRIF: expression linked to the differentiation of Rcho-1 cells
REFERENCE   6  (bases 1 to 1391)
  AUTHORS   Tamura,N., Ohno,K., Katayama,T., Kanayama,N. and Sato,K.
  TITLE     The PDZ-LIM protein CLP36 is required for actin stress fiber
            formation and focal adhesion assembly in BeWo cells
  JOURNAL   Biochem Biophys Res Commun 364 (3), 589-594 (2007)
   PUBMED   17964547
  REMARK    GeneRIF: These findings indicate that CLP36 plays a critical role
            in stress fiber formation and the assembly of focal adhesions in
            BeWo cells.
REFERENCE   7  (bases 1 to 1391)
  AUTHORS   Kioussi,C., Briata,P., Baek,S.H., Rose,D.W., Hamblet,N.S.,
            Herman,T., Ohgi,K.A., Lin,C., Gleiberman,A., Wang,J., Brault,V.,
            Ruiz-Lozano,P., Nguyen,H.D., Kemler,R., Glass,C.K.,
            Wynshaw-Boris,A. and Rosenfeld,M.G.
  TITLE     Identification of a Wnt/Dvl/beta-Catenin --> Pitx2 pathway
            mediating cell-type-specific proliferation during development
  JOURNAL   Cell 111 (5), 673-685 (2002)
   PUBMED   12464179
REFERENCE   8  (bases 1 to 1391)
  AUTHORS   Bauer,K., Kratzer,M., Otte,M., de Quintana,K.L., Hagmann,J.,
            Arnold,G.J., Eckerskorn,C., Lottspeich,F. and Siess,W.
  TITLE     Human CLP36, a PDZ-domain and LIM-domain protein, binds to
            alpha-actinin-1 and associates with actin filaments and stress
            fibers in activated platelets and endothelial cells
  JOURNAL   Blood 96 (13), 4236-4245 (2000)
   PUBMED   11110697
REFERENCE   9  (bases 1 to 1391)
  AUTHORS   Kotaka,M., Kostin,S., Ngai,S., Chan,K., Lau,Y., Lee,S.M., Li,Hy.,
            Ng,E.K., Schaper,J., Tsui,S.K., Fung,Kp., Lee,Cy. and Waye,M.M.
  TITLE     Interaction of hCLIM1, an enigma family protein, with alpha-actinin
            2
  JOURNAL   J Cell Biochem 78 (4), 558-565 (2000)
   PUBMED   10861853
REFERENCE   10 (bases 1 to 1391)
  AUTHORS   Wang,H., Harrison-Shostak,D.C., Lemasters,J.J. and Herman,B.
  TITLE     Cloning of a rat cDNA encoding a novel LIM domain protein with high
            homology to rat RIL
  JOURNAL   Gene 165 (2), 267-271 (1995)
   PUBMED   8522188
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from U23769.1.
            
            On Feb 21, 2013 this sequence version replaced NM_017365.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: U23769.1, FQ214797.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760400, SAMEA5760476
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1391              U23769.1           1-1391
FEATURES             Location/Qualifiers
     source          1..1391
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="Sprague-Dawley"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q54"
     gene            1..1391
                     /gene="Pdlim1"
                     /gene_synonym="CLP36"
                     /note="PDZ and LIM domain 1"
                     /db_xref="GeneID:54133"
                     /db_xref="RGD:68324"
     exon            1..162
                     /gene="Pdlim1"
                     /gene_synonym="CLP36"
                     /inference="alignment:Splign:2.1.0"
     CDS             67..1050
                     /gene="Pdlim1"
                     /gene_synonym="CLP36"
                     /note="elfin; LIM domain protein CLP-36; C-terminal LIM
                     domain protein 1; LIM protein"
                     /codon_start=1
                     /product="PDZ and LIM domain protein 1"
                     /protein_id="NP_059061.1"
                     /db_xref="GeneID:54133"
                     /db_xref="RGD:68324"
                     /translation="MTTQQIVLQGPGPWGFRLVGGKDFEQPLAISRVTPGSKAAIANL
                     CIGDLITAIDGEDTSSMTHLEAQNKIKGCVDNMTLTVSRSEQKIWSPLVTEEGKRHPY
                     KMNLASEPQEVLHIGSAHNRSAMPFTASPAPGTRVITNQYNSPTGLYSSENISNFNNA
                     VESKTSASGEEANSRPSAQPHPSGGLIIDKESEVYKMLQEKQELNEPPKQSTSFLVLQ
                     EILESDGKGDPNKPSGFRSVKAPVTKVAASVGNAQKLPICDKCGTGIVGVFVKLRDHH
                     PHPECYVCTDCGINLKQKGHFFVGDQIYCEKHARERVTPPEGYDVVTVFPK"
     exon            163..314
                     /gene="Pdlim1"
                     /gene_synonym="CLP36"
                     /inference="alignment:Splign:2.1.0"
     exon            315..399
                     /gene="Pdlim1"
                     /gene_synonym="CLP36"
                     /inference="alignment:Splign:2.1.0"
     exon            400..593
                     /gene="Pdlim1"
                     /gene_synonym="CLP36"
                     /inference="alignment:Splign:2.1.0"
     exon            594..745
                     /gene="Pdlim1"
                     /gene_synonym="CLP36"
                     /inference="alignment:Splign:2.1.0"
     exon            746..863
                     /gene="Pdlim1"
                     /gene_synonym="CLP36"
                     /inference="alignment:Splign:2.1.0"
     exon            864..1391
                     /gene="Pdlim1"
                     /gene_synonym="CLP36"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ccgggatccc tgcgcgccgt ggtgttctgt gccttgccgg tctgttccct ccgattgtgc
       61 ctagcaatga ccacccagca gattgttctc cagggcccgg gaccctgggg tttccgactc
      121 gtgggcggca aggactttga gcaacctctc gccatttccc gggtcactcc cgggagcaag
      181 gctgctatag ctaacttatg cataggagat ttgatcacag ccattgatgg ggaagatacc
      241 agcagtatga cacacttgga agctcagaac aaaatcaagg gctgcgtaga caacatgacg
      301 ctcacagtat ccaggtctga gcagaagatt tggtctcctc tagtgaccga ggaggggaaa
      361 cgtcacccct acaagatgaa tttagcgtcg gaaccccaag aagtcctgca catcggaagt
      421 gcccacaacc gtagtgctat gccatttacc gcctcacctg ctcctggcac ccgggtcatc
      481 acaaaccagt acaacagccc taccggcctc tactcatctg aaaacatctc taacttcaac
      541 aatgcagtgg agtcaaagac ctcagccagt ggggaggagg cgaacagcag gccctcggct
      601 cagcctcatc cctccggcgg ccttatcatc gacaaggaat ccgaagttta caagatgctt
      661 caggagaagc aagagttaaa cgagcccccc aaacagtcca catcattcct ggttctgcag
      721 gagatcctgg agtcggatgg gaaaggggac cccaacaagc catcaggatt tagaagtgtt
      781 aaagctccag tcaccaaagt ggctgcatct gttggaaatg ctcagaagct gcccatctgt
      841 gacaaatgtg gaaccggcat tgttggtgtg tttgtgaagc tgagggacca tcatccccac
      901 cctgaatgtt atgtgtgcac cgactgtggc atcaacctga aacagaaggg ccatttcttt
      961 gtaggggatc agatttattg tgaaaagcat gcccgggaga gggtcacacc acctgagggc
     1021 tatgatgtgg tcacagtgtt ccccaagtga tcgagaggac ctgccctgtc tgctgccctc
     1081 cagcctgcct gctgcacctg gttgtcagaa tgttctggtt ctctcctccc tgacagtcct
     1141 gtgcttagtg ttagtcctgc tcagtaaaca ttgagtttct cctgtactga ctgaccctga
     1201 ctggcagtgt gacacctgct tttacattac cgggaggtgg ttttgtccct gtcccctcac
     1261 ccacaccaca atgcaccttc ttcccttgga gtcttccctg ctgaaaatgg acattggtca
     1321 cattggaatt aagccaaatg ttttatctct gatgttactt tgttttactt aataaattta
     1381 gactttaaag c
//
