LOCUS       NM_001416003            2979 bp    mRNA    linear   ROD 09-APR-2024
DEFINITION  Rattus norvegicus phosphodiesterase 6C (Pde6c), mRNA.
ACCESSION   NM_001416003 XM_006231329
VERSION     NM_001416003.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2979)
  AUTHORS   Lei,B.
  TITLE     Rod-driven OFF pathway responses in the distal retina: dark-adapted
            flicker electroretinogram in mouse
  JOURNAL   PLoS One 7 (8), e43856 (2012)
   PUBMED   22937111
REFERENCE   2  (bases 1 to 2979)
  AUTHORS   Won,J., Shi,L.Y., Hicks,W., Wang,J., Hurd,R., Naggert,J.K.,
            Chang,B. and Nishina,P.M.
  TITLE     Mouse model resources for vision research
  JOURNAL   J Ophthalmol 2011, 391384 (2011)
   PUBMED   21052544
REFERENCE   3  (bases 1 to 2979)
  AUTHORS   Lei,B., Yao,G., Zhang,K., Hofeldt,K.J. and Chang,B.
  TITLE     Study of rod- and cone-driven oscillatory potentials in mice
  JOURNAL   Invest Ophthalmol Vis Sci 47 (6), 2732-2738 (2006)
   PUBMED   16723493
REFERENCE   4  (bases 1 to 2979)
  AUTHORS   Cote,R.H.
  TITLE     Characteristics of photoreceptor PDE (PDE6): similarities and
            differences to PDE5
  JOURNAL   Int J Impot Res 16 Suppl 1, S28-S33 (2004)
   PUBMED   15224133
  REMARK    Review article
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000001.1.
            
            On Jan 6, 2023 this sequence version replaced XM_006231329.3.
            
            ##Evidence-Data-START##
            RNAseq introns :: partial sample support SAMEA5760383, SAMEA5760389
                              [ECO:0000350]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            inferred exon combination :: based on alignments, homology
            RefSeq Select criteria    :: based on conservation, expression,
                                         longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-672               JAXUCZ010000001.1  245322015-245322686
            673-825             JAXUCZ010000001.1  245331429-245331581
            826-915             JAXUCZ010000001.1  245331681-245331770
            916-1056            JAXUCZ010000001.1  245332847-245332987
            1057-1131           JAXUCZ010000001.1  245342001-245342075
            1132-1196           JAXUCZ010000001.1  245343005-245343069
            1197-1263           JAXUCZ010000001.1  245343161-245343227
            1264-1311           JAXUCZ010000001.1  245345107-245345154
            1312-1461           JAXUCZ010000001.1  245349098-245349247
            1462-1605           JAXUCZ010000001.1  245350127-245350270
            1606-1674           JAXUCZ010000001.1  245351413-245351481
            1675-1821           JAXUCZ010000001.1  245353423-245353569
            1822-1929           JAXUCZ010000001.1  245353802-245353909
            1930-2039           JAXUCZ010000001.1  245354258-245354367
            2040-2127           JAXUCZ010000001.1  245360677-245360764
            2128-2228           JAXUCZ010000001.1  245366842-245366942
            2229-2336           JAXUCZ010000001.1  245369991-245370098
            2337-2400           JAXUCZ010000001.1  245370200-245370263
            2401-2475           JAXUCZ010000001.1  245373875-245373949
            2476-2559           JAXUCZ010000001.1  245374038-245374121
            2560-2716           JAXUCZ010000001.1  245374676-245374832
            2717-2979           JAXUCZ010000001.1  245377599-245377861
FEATURES             Location/Qualifiers
     source          1..2979
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q53"
     gene            1..2979
                     /gene="Pde6c"
                     /note="phosphodiesterase 6C"
                     /db_xref="GeneID:361752"
                     /db_xref="RGD:1309844"
     exon            1..672
                     /gene="Pde6c"
                     /inference="alignment:Splign:2.1.0"
     CDS             193..2778
                     /gene="Pde6c"
                     /EC_number="3.1.4.35"
                     /note="phosphodiesterase 6C, cGMP specific, cone, alpha
                     prime"
                     /codon_start=1
                     /product="cone cGMP-specific 3',5'-cyclic
                     phosphodiesterase subunit alpha'"
                     /protein_id="NP_001402932.1"
                     /db_xref="GeneID:361752"
                     /db_xref="RGD:1309844"
                     /translation="MGEISQDAVERYLEENPCFAKEYFDKKLRVETPGAIFKNSHAGV
                     QAGTSLPRMTQVEESALCLELLQHMQDETGSAEQVAHRALQRLARLLQAECCSMFSCR
                     SRNGIPEVASRLLNVTPTSKFEDNLVAPNREVVFPLDIGIVGWVAHVKKALNVSNVKK
                     NSHFSDFMDKQTGYVTRNLLAVPIMTGKEVLAVVMAVNKINAPEFSKQDEEVFSKYLS
                     FVAIALRLQHTSYLYSVESRRSQILMWSANKVFEELTDVERQFHKALYTVRTYLNCER
                     YSIGLLDMTKEKEFYDEWPIKLGEVEPYKGPKTPDGREIIFYKIIDYILHGKEEISVI
                     PSPPADHWTLVSGLPTYIAENGFICNMMNAPADEYFTFQKGPVDETGWVIKNVLSLPI
                     VNKKEDIVGVATFYNRKDGKPFDEHDEHITETLTQFLGWSLLNTDTYERVNKLESRKD
                     IAQEMIMNLTKATPSEISSILKFKEKLNIDVIEECEERQLLAILKEELPDPRAADLYE
                     FRFSDFPVTEHELVKCGLRLFLEINVVEKFKVPVEVLTRWMYTVRKGYRPVTYHNWRH
                     GFNVGQTMFTLLMTGRLKKYYTDLEAFAMLAAAFCHDIDHRGTNNLYQMKSTSPLARL
                     HGTSILERHHLEYSKTLLQDESLNIFQNLSKRQFETVIHLFEVAIIATDLALYFKKRT
                     MFQKIVDTCEQMQSEEETIKYVTADPTKKEVIMAMMMTACDLSAITKPWEVQSQVALL
                     VANEFWEQGDLERTVLQQQPIPMMDRNKKGELPKLQVGFIDFVCTFVYKEFSRFHGEI
                     TPMLTGLQNNRVEWKSLAEEYEAKVKVTEEEVGKQEEVTSDGKAATDLGSSTDDKKSK
                     TCLML"
     exon            673..825
                     /gene="Pde6c"
                     /inference="alignment:Splign:2.1.0"
     exon            826..915
                     /gene="Pde6c"
                     /inference="alignment:Splign:2.1.0"
     exon            916..1056
                     /gene="Pde6c"
                     /inference="alignment:Splign:2.1.0"
     exon            1057..1131
                     /gene="Pde6c"
                     /inference="alignment:Splign:2.1.0"
     exon            1132..1196
                     /gene="Pde6c"
                     /inference="alignment:Splign:2.1.0"
     exon            1197..1263
                     /gene="Pde6c"
                     /inference="alignment:Splign:2.1.0"
     exon            1264..1311
                     /gene="Pde6c"
                     /inference="alignment:Splign:2.1.0"
     exon            1312..1461
                     /gene="Pde6c"
                     /inference="alignment:Splign:2.1.0"
     exon            1462..1605
                     /gene="Pde6c"
                     /inference="alignment:Splign:2.1.0"
     exon            1606..1674
                     /gene="Pde6c"
                     /inference="alignment:Splign:2.1.0"
     exon            1675..1821
                     /gene="Pde6c"
                     /inference="alignment:Splign:2.1.0"
     exon            1822..1929
                     /gene="Pde6c"
                     /inference="alignment:Splign:2.1.0"
     exon            1930..2039
                     /gene="Pde6c"
                     /inference="alignment:Splign:2.1.0"
     exon            2040..2127
                     /gene="Pde6c"
                     /inference="alignment:Splign:2.1.0"
     exon            2128..2228
                     /gene="Pde6c"
                     /inference="alignment:Splign:2.1.0"
     exon            2229..2336
                     /gene="Pde6c"
                     /inference="alignment:Splign:2.1.0"
     exon            2337..2400
                     /gene="Pde6c"
                     /inference="alignment:Splign:2.1.0"
     exon            2401..2475
                     /gene="Pde6c"
                     /inference="alignment:Splign:2.1.0"
     exon            2476..2559
                     /gene="Pde6c"
                     /inference="alignment:Splign:2.1.0"
     exon            2560..2716
                     /gene="Pde6c"
                     /inference="alignment:Splign:2.1.0"
     exon            2717..2979
                     /gene="Pde6c"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 atctcgtgag tcccaggcag cttggaagaa ctactaagca accttcctgc ttctcttttg
       61 gggatttaat gagggaccac ctgcggcttc cttggtgatt tttgaccagg atgtatttcc
      121 tcgttatgct gctcagggta tcgctctgag gaaccctccg ctctgggtag cagcagcaac
      181 acaagccaca acatggggga gatcagccaa gatgccgtgg agcgctacct ggaggagaac
      241 ccttgttttg ccaaggagta ctttgacaag aagctgcggg tggagacacc gggggcgatc
      301 ttcaaaaaca gccatgcggg ggtccaggct ggcacgtctc tcccccggat gacacaggtg
      361 gaggagtcgg ccttgtgcct ggagctacta cagcatatgc aggacgagac aggaagcgcc
      421 gagcaggtgg ctcacagggc cctgcagagg ctggctcggc ttctacaggc tgaatgctgc
      481 agtatgttct catgccgatc aagaaacggc ataccggagg tggcctccag gctgctgaac
      541 gtcaccccaa cttctaagtt tgaggacaac ctcgtggccc ctaacagaga agttgtattt
      601 ccgttggaca ttgggatagt tggctgggtc gctcatgtga agaaagccct taatgtctca
      661 aatgtcaaaa agaacagcca tttttctgac tttatggaca agcaaactgg atatgtcacc
      721 aggaatctgc tggcagtccc catcatgacg ggcaaggagg ttcttgctgt ggtcatggca
      781 gtgaacaaaa tcaacgctcc cgagttttcc aaacaggatg aggaggtctt ttccaagtac
      841 ctcagctttg ttgcgatcgc tctaaggctg cagcacacca gttacctgta cagtgtggag
      901 tcccggagaa gccagatcct tatgtggtca gccaataaag tattcgagga gctcactgac
      961 gttgagcgac agtttcacaa ggccctgtac accgtcagaa catacctgaa ctgcgagcgc
     1021 tactccattg gtcttctgga catgaccaag gagaaggaat tttacgacga gtggccaatc
     1081 aagcttggag aagttgaacc ttataaagga ccaaagactc cagatggcag ggaaatcatc
     1141 ttttataaaa tcatcgatta cattttacat ggaaaagaag agatcagcgt gattccgtca
     1201 cctccagcag atcactggac actcgttagt ggattgccaa catacattgc tgaaaatgga
     1261 tttatctgta acatgatgaa cgcccctgca gatgagtact tcacattcca gaaaggacca
     1321 gtggacgaaa ctggctgggt cattaaaaat gtcttgtccc tgcctattgt caacaagaaa
     1381 gaagacatcg tgggtgtggc tacgttttac aaccggaagg atgggaaacc ctttgatgag
     1441 catgacgaac acatcactga gactttaacc cagtttcttg gatggtctct tttaaacacc
     1501 gatacctatg agcgagtgaa caagctggaa agccgaaagg acattgctca ggaaatgatt
     1561 atgaacctca ccaaagccac ccctagtgaa atcagctcta ttttgaaatt taaagagaag
     1621 ttaaacatag atgtaattga agaatgtgag gagagacagc tcctggccat attgaaggag
     1681 gagctgcccg acccaagagc agcagacctg tacgagttcc gtttcagcga cttccccgtt
     1741 acggagcacg agttggttaa atgcgggctg cggctgtttt tggagataaa tgtggtggag
     1801 aaattcaaag taccggtcga ggttcttaca cggtggatgt acacagttcg gaaagggtac
     1861 cgccctgtca cctaccacaa ctggcgacac ggattcaacg tggggcagac catgttcact
     1921 ttgttaatga ctgggagact aaagaaatac tacacagacc tcgaagcttt tgccatgctt
     1981 gctgctgcct tctgccatga cattgaccac agaggaacca ataacttgta ccaaatgaag
     2041 tccacatctc cactggcaag gcttcatggg acttccattt tagagcgaca tcacctggaa
     2101 tatagcaaga ctctcttgca ggatgagagt ttaaacatct tccagaatct aagcaagcgg
     2161 cagtttgaaa cggtgatcca cttgtttgag gttgcgataa tagcaactga cctggcactc
     2221 tatttcaaga agagaaccat gtttcaaaag attgttgata cctgtgaaca gatgcaaagc
     2281 gaagaagaaa ccatcaaata tgtaaccgcc gacccgacca aaaaggaggt catcatggcc
     2341 atgatgatga ctgcctgcga cctgtctgcc atcaccaagc cctgggaggt gcagagtcag
     2401 gtagcacttc tggttgcaaa tgaattttgg gaacaaggag atctggaaag gacagtgctt
     2461 cagcagcaac caattcctat gatggacaga aacaaaaagg gtgaactccc aaaacttcaa
     2521 gtgggattca ttgattttgt ttgtactttt gtatataagg agttctctcg ctttcacggg
     2581 gagatcaccc ccatgctgac cggccttcag aataacagag tggaatggaa atcactggcg
     2641 gaggagtatg aggcgaaggt gaaggtgact gaagaggagg tgggaaagca ggaagaagtt
     2701 acctcagatg gaaaagctgc cacagattta ggaagcagca cagatgacaa aaagtccaaa
     2761 acgtgcttaa tgttataatc taacccgtct gtatttcaag tatcatctta gttcccatgg
     2821 gaaaataaaa atgtccaaaa gaacctcctt gagttctttc agtgaccatg aaatgacgga
     2881 agagaaggag ccccagagac tctgctatgg gactatgccc agatcatcta ttgatgaccc
     2941 ggaaacctgc gagctaaata aagttcagtc aaaaaacaa
//
