LOCUS       NM_001389234            8353 bp    mRNA    linear   ROD 24-JUN-2024
DEFINITION  Rattus norvegicus phosphodiesterase 4D interacting protein
            (Pde4dip), transcript variant 3, mRNA.
ACCESSION   NM_001389234 XM_017591087
VERSION     NM_001389234.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 8353)
  AUTHORS   Bouguenina,H., Salaun,D., Mangon,A., Muller,L., Baudelet,E.,
            Camoin,L., Tachibana,T., Cianferani,S., Audebert,S.,
            Verdier-Pinard,P. and Badache,A.
  TITLE     EB1-binding-myomegalin protein complex promotes centrosomal
            microtubules functions
  JOURNAL   Proc Natl Acad Sci U S A 114 (50), E10687-E10696 (2017)
   PUBMED   29162697
REFERENCE   2  (bases 1 to 8353)
  AUTHORS   Wu,J., de Heus,C., Liu,Q., Bouchet,B.P., Noordstra,I., Jiang,K.,
            Hua,S., Martin,M., Yang,C., Grigoriev,I., Katrukha,E.A.,
            Altelaar,A.F.M., Hoogenraad,C.C., Qi,R.Z., Klumperman,J. and
            Akhmanova,A.
  TITLE     Molecular Pathway of Microtubule Organization at the Golgi
            Apparatus
  JOURNAL   Dev Cell 39 (1), 44-60 (2016)
   PUBMED   27666745
REFERENCE   3  (bases 1 to 8353)
  AUTHORS   Uys,G.M., Ramburan,A., Loos,B., Kinnear,C.J., Korkie,L.J.,
            Mouton,J., Riedemann,J. and Moolman-Smook,J.C.
  TITLE     Myomegalin is a novel A-kinase anchoring protein involved in the
            phosphorylation of cardiac myosin binding protein C
  JOURNAL   BMC Cell Biol 12, 18 (2011)
   PUBMED   21569246
  REMARK    GeneRIF: MMGL isoform 4 is involved in the phosphorylation of
            Cardiac Myosin Binding Protein-C as well as cardiac troponin I.
            Publication Status: Online-Only
REFERENCE   4  (bases 1 to 8353)
  AUTHORS   Jakobsen,L., Vanselow,K., Skogs,M., Toyoda,Y., Lundberg,E.,
            Poser,I., Falkenby,L.G., Bennetzen,M., Westendorf,J., Nigg,E.A.,
            Uhlen,M., Hyman,A.A. and Andersen,J.S.
  TITLE     Novel asymmetrically localizing components of human centrosomes
            identified by complementary proteomics methods
  JOURNAL   EMBO J 30 (8), 1520-1535 (2011)
   PUBMED   21399614
REFERENCE   5  (bases 1 to 8353)
  AUTHORS   Soejima,H., Kawamoto,S., Akai,J., Miyoshi,O., Arai,Y., Morohka,T.,
            Matsuo,S., Niikawa,N., Kimura,A., Okubo,K. and Mukai,T.
  TITLE     Isolation of novel heart-specific genes using the BodyMap database
  JOURNAL   Genomics 74 (1), 115-120 (2001)
   PUBMED   11374908
REFERENCE   6  (bases 1 to 8353)
  AUTHORS   Verde,I., Pahlke,G., Salanova,M., Zhang,G., Wang,S., Coletti,D.,
            Onuffer,J., Jin,S.L. and Conti,M.
  TITLE     Myomegalin is a novel protein of the golgi/centrosome that
            interacts with a cyclic nucleotide phosphodiesterase
  JOURNAL   J Biol Chem 276 (14), 11189-11198 (2001)
   PUBMED   11134006
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000002.1.
            
            On Dec 1, 2020 this sequence version replaced XM_017591087.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            RNAseq introns :: mixed sample support SAMEA5760383, SAMEA5760386
                              [ECO:0006172]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-219               JAXUCZ010000002.1  188178267-188178485 c
            220-275             JAXUCZ010000002.1  188135602-188135657 c
            276-427             JAXUCZ010000002.1  188133574-188133725 c
            428-538             JAXUCZ010000002.1  188116503-188116613 c
            539-615             JAXUCZ010000002.1  188085359-188085435 c
            616-739             JAXUCZ010000002.1  188082180-188082303 c
            740-915             JAXUCZ010000002.1  188081818-188081993 c
            916-1033            JAXUCZ010000002.1  188081413-188081530 c
            1034-1165           JAXUCZ010000002.1  188050848-188050979 c
            1166-1285           JAXUCZ010000002.1  188049710-188049829 c
            1286-1378           JAXUCZ010000002.1  188049386-188049478 c
            1379-1591           JAXUCZ010000002.1  188049066-188049278 c
            1592-1750           JAXUCZ010000002.1  188047587-188047745 c
            1751-1864           JAXUCZ010000002.1  188046573-188046686 c
            1865-2002           JAXUCZ010000002.1  188045932-188046069 c
            2003-2182           JAXUCZ010000002.1  188044682-188044861 c
            2183-2377           JAXUCZ010000002.1  188043472-188043666 c
            2378-2548           JAXUCZ010000002.1  188039485-188039655 c
            2549-2630           JAXUCZ010000002.1  188039238-188039319 c
            2631-2722           JAXUCZ010000002.1  188038416-188038507 c
            2723-2839           JAXUCZ010000002.1  188035392-188035508 c
            2840-2977           JAXUCZ010000002.1  188035071-188035208 c
            2978-3090           JAXUCZ010000002.1  188034256-188034368 c
            3091-3218           JAXUCZ010000002.1  188033134-188033261 c
            3219-3307           JAXUCZ010000002.1  188023032-188023120 c
            3308-3540           JAXUCZ010000002.1  188016318-188016550 c
            3541-3973           JAXUCZ010000002.1  188011278-188011710 c
            3974-4166           JAXUCZ010000002.1  188009372-188009564 c
            4167-4283           JAXUCZ010000002.1  188008187-188008303 c
            4284-4812           JAXUCZ010000002.1  188007140-188007668 c
            4813-5048           JAXUCZ010000002.1  188005480-188005715 c
            5049-5100           JAXUCZ010000002.1  188004201-188004252 c
            5101-5324           JAXUCZ010000002.1  188003017-188003240 c
            5325-5426           JAXUCZ010000002.1  188002312-188002413 c
            5427-5612           JAXUCZ010000002.1  188000147-188000332 c
            5613-5861           JAXUCZ010000002.1  187996531-187996779 c
            5862-5993           JAXUCZ010000002.1  187995641-187995772 c
            5994-6113           JAXUCZ010000002.1  187994898-187995017 c
            6114-6303           JAXUCZ010000002.1  187992912-187993101 c
            6304-6428           JAXUCZ010000002.1  187992264-187992388 c
            6429-6662           JAXUCZ010000002.1  187989388-187989621 c
            6663-6782           JAXUCZ010000002.1  187987865-187987984 c
            6783-7003           JAXUCZ010000002.1  187986854-187987074 c
            7004-7147           JAXUCZ010000002.1  187985991-187986134 c
            7148-7286           JAXUCZ010000002.1  187984868-187985006 c
            7287-7333           JAXUCZ010000002.1  187984571-187984617 c
            7334-8353           JAXUCZ010000002.1  187982002-187983021 c
FEATURES             Location/Qualifiers
     source          1..8353
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="2"
                     /map="2q34"
     gene            1..8353
                     /gene="Pde4dip"
                     /note="phosphodiesterase 4D interacting protein"
                     /db_xref="GeneID:64183"
                     /db_xref="RGD:708410"
     exon            1..219
                     /gene="Pde4dip"
                     /inference="alignment:Splign:2.1.0"
     CDS             38..7375
                     /gene="Pde4dip"
                     /note="isoform 3 is encoded by transcript variant 3;
                     phosphodiesterase-binding protein clone 46; myomegalin"
                     /codon_start=1
                     /product="myomegalin isoform 3"
                     /protein_id="NP_001376163.1"
                     /db_xref="GeneID:64183"
                     /db_xref="RGD:708410"
                     /translation="MKRTDSGSICHHAPPPCWAHHAPRQSPRQPSSRERRPPERAGSW
                     AVAAEEEEAVSSAPWMRHYFGEEDGEMVPRTSNAAAFLSDTKDRGPPVQSQVWRSAEK
                     VPFGQAHSLRAFEKPPLVQTQALRDFEKHLNDLKKENFSLKLRIYFLEERMQQKYEVS
                     REDVYKRNIELKVEVESLKRELQDRKQHLHKTWADEEDLNSQNEAELRRQVEEPQQET
                     EHVYELLDNNIQLLQEESRFAKDEATQMETLVEAEKGCNLELSERWKDATKNREDAPG
                     DQVKLDQYSAALAQRDRRIEELRQSLAAQEGLVEQLSREKQQLLHLLEEPGGMEVQPM
                     PKGLPTQQKPDLNETPTTQPSVSDSHLAELQDKIQQTEVTNKILQEKLNDMSCELRSA
                     QESSQKQDTTIQSLKEMLKSRESETEELYQVIEGQNDTMAKLREMLHQSQLGQLQSSE
                     GIAPAQQQVALLDLQSALFCSQLEIQKLQRLLRQKERQLADGKRCMQFVEAAAQEREQ
                     QKEAAWKHNQELRKALQHLQGELHSKSQQLHVLEAEKYNEIRTQGQNIQHLSHSLSHK
                     EQLIQELQELLQYRDTTDKTLDTNEVFLEKLRQRIQDRAVALERVIDEKFSALEEKDK
                     ELRQLRLAVRDRDHDLERLRCVLSANEATMQSMESLLRARGLEVEQLTATCQNLQWLK
                     EELETKFGHWQKEQESIIQQLQTSLHDRNKEVEDLSATLLHKLGPGQSEVAEELCQRL
                     QRKERVLQDLLSDRNKQAMEHEMEVQGLLQSMGTREQERQAVAEKMVQAFMERNSELQ
                     ALRQYLGGKELMAASQAFISNQPAGATSVGPHHGEQTDQGSTQMPSRDDSTSLTAREE
                     ASIPRSTLGDSDTVAGLEKELSNAKEELELMAKKERESQIELSALQSMMAVQEEELQV
                     QAADLESLTRNIQIKEDLIKDLQMQLVDPEDMPAMERLTQEVLLLREKVASVEPQGQE
                     GSENRRQQLLLMLEGLVDERSRLNEALQAERQLYSSLVKFHAQPETSERDRTLQVELE
                     GAQVLRSRLEEVLGRSLERLSRLETLAAIGGATAGDETEDTSTQFTDSIEEEAAHNSH
                     QQLIKVSLEKSLTTMETQNTCLQPPSPVGEDGNRHLQEEMLHLRAEIHQHLEEKRKAE
                     AELKELKAQIEEAGFSSVSHIRNTMLSLCLENAELKEQMGEAMSDGWEVEEDKEKGEV
                     MVETVVAKGGLSEDSLQAEFRKVQGRLKSAYNIINLLKEQLVLRSSEGNTKEMPEFLV
                     RLAREVDRMNMGLPSSEKHQHQEQENMTARPGPRPQSLKLGTALSVDGYQLENKSQAQ
                     DSGHQPQFSLPGSTKHLRSQLAQCRQRYQDLQEKLLISEATVFAQANQLEKYRAILSE
                     SLVKQDSKQIQVDLQDLGYETCGRSENEAEREETTSPECEEHGNLRPVVLVEGLCSEQ
                     GYLDPVLVSSPVKKPLENKPGKREEFQAQGTSDDSSLLRKDIRDLKAQLQNAYKVIQN
                     LRSRVRSLSATSDYSSSLERPRKLRAVATLEGASPHSVTDEDEGWLSDGTGAFYPPGL
                     QAKKNLENLIQRVSQLEAQLPKTGLEGKLAEELRSASWPGKYDSLIQDQARELSYLRQ
                     KIREGRGICYLLTQHSKDTVKSFEDLLRSNDIDYYLGQSFREQLAQGGQLTDRLTSKL
                     STKDHKSEKEEAGLEPLALRLSRELQEKEKVIEVLQAKLDTRSLSPPSSHAASDSHRS
                     ASSTSFLSDDIEACSDMDVASEYTHYEEKKPSPSNSAASASQGLKGEPRSSSISLPTP
                     QNPPKEASQAQPGFHFNSIPKPASLSQAPMHFTVPSFMPFGPSGPPLLGCCETPVVSL
                     AEAQQELQMLQKQLGESVSIAPPTSTSTLLSNHTEASSPRYSNPAQPHSPARGTIELG
                     RILEPGYLGSGQWDMMRPQKGSISGELSSGSSMYQLNSKPTGADLLEEHLGEIRNLRQ
                     RLEESICVNDRLREQLQHRLSSTARENGSTSHFYSQGLESMPQLYNENRALREENQSL
                     QTRLSHASRGHSQEVDHLREALLSSSSQLQELEKELEQQKAERRQLLEDLQEKQDEIV
                     HFREERLSLQENNSRLQHKLALLQQQCEEKQQLSLSLQSELQIYESLYENPKKGLKAF
                     SLDSCYQVPGELSCLVAEIRALRVQLEQSIQVNNRLRLQLEQQMDHGAGKASLSSCPV
                     NQSFSAKAELANQQPPFQGSAASPPVRDVGLNSPAVVLPSNSCSVPGSDSAIISRTNN
                     GSDESAATKTPPKMEVDAADGPFASGHGRHVIGHVDDYDTLQQQIGEGKLLIQKILSL
                     TRPARSVPALDAQGTEAPGTKSVHELRSSARALNHSLEESASLLTMFWRAALPNSHGS
                     VLVGEEGKLMEKELLDLRAQVSQQQQLLQSTAVRLKTANQRKKSMEQFIVSHLTRTHD
                     VLKKARTNLEMKSFRALMCTPAL"
     exon            220..275
                     /gene="Pde4dip"
                     /inference="alignment:Splign:2.1.0"
     exon            276..427
                     /gene="Pde4dip"
                     /inference="alignment:Splign:2.1.0"
     exon            428..538
                     /gene="Pde4dip"
                     /inference="alignment:Splign:2.1.0"
     exon            539..615
                     /gene="Pde4dip"
                     /inference="alignment:Splign:2.1.0"
     exon            616..739
                     /gene="Pde4dip"
                     /inference="alignment:Splign:2.1.0"
     exon            740..915
                     /gene="Pde4dip"
                     /inference="alignment:Splign:2.1.0"
     exon            916..1033
                     /gene="Pde4dip"
                     /inference="alignment:Splign:2.1.0"
     exon            1034..1165
                     /gene="Pde4dip"
                     /inference="alignment:Splign:2.1.0"
     exon            1166..1285
                     /gene="Pde4dip"
                     /inference="alignment:Splign:2.1.0"
     exon            1286..1378
                     /gene="Pde4dip"
                     /inference="alignment:Splign:2.1.0"
     exon            1379..1591
                     /gene="Pde4dip"
                     /inference="alignment:Splign:2.1.0"
     exon            1592..1750
                     /gene="Pde4dip"
                     /inference="alignment:Splign:2.1.0"
     exon            1751..1864
                     /gene="Pde4dip"
                     /inference="alignment:Splign:2.1.0"
     exon            1865..2002
                     /gene="Pde4dip"
                     /inference="alignment:Splign:2.1.0"
     exon            2003..2182
                     /gene="Pde4dip"
                     /inference="alignment:Splign:2.1.0"
     exon            2183..2377
                     /gene="Pde4dip"
                     /inference="alignment:Splign:2.1.0"
     exon            2378..2548
                     /gene="Pde4dip"
                     /inference="alignment:Splign:2.1.0"
     exon            2549..2630
                     /gene="Pde4dip"
                     /inference="alignment:Splign:2.1.0"
     exon            2631..2722
                     /gene="Pde4dip"
                     /inference="alignment:Splign:2.1.0"
     exon            2723..2839
                     /gene="Pde4dip"
                     /inference="alignment:Splign:2.1.0"
     exon            2840..2977
                     /gene="Pde4dip"
                     /inference="alignment:Splign:2.1.0"
     exon            2978..3090
                     /gene="Pde4dip"
                     /inference="alignment:Splign:2.1.0"
     exon            3091..3218
                     /gene="Pde4dip"
                     /inference="alignment:Splign:2.1.0"
     exon            3219..3307
                     /gene="Pde4dip"
                     /inference="alignment:Splign:2.1.0"
     exon            3308..3540
                     /gene="Pde4dip"
                     /inference="alignment:Splign:2.1.0"
     exon            3541..3973
                     /gene="Pde4dip"
                     /inference="alignment:Splign:2.1.0"
     exon            3974..4166
                     /gene="Pde4dip"
                     /inference="alignment:Splign:2.1.0"
     exon            4167..4283
                     /gene="Pde4dip"
                     /inference="alignment:Splign:2.1.0"
     exon            4284..4812
                     /gene="Pde4dip"
                     /inference="alignment:Splign:2.1.0"
     exon            4813..5048
                     /gene="Pde4dip"
                     /inference="alignment:Splign:2.1.0"
     exon            5049..5100
                     /gene="Pde4dip"
                     /inference="alignment:Splign:2.1.0"
     exon            5101..5324
                     /gene="Pde4dip"
                     /inference="alignment:Splign:2.1.0"
     exon            5325..5426
                     /gene="Pde4dip"
                     /inference="alignment:Splign:2.1.0"
     exon            5427..5612
                     /gene="Pde4dip"
                     /inference="alignment:Splign:2.1.0"
     exon            5613..5861
                     /gene="Pde4dip"
                     /inference="alignment:Splign:2.1.0"
     exon            5862..5993
                     /gene="Pde4dip"
                     /inference="alignment:Splign:2.1.0"
     exon            5994..6113
                     /gene="Pde4dip"
                     /inference="alignment:Splign:2.1.0"
     exon            6114..6303
                     /gene="Pde4dip"
                     /inference="alignment:Splign:2.1.0"
     exon            6304..6428
                     /gene="Pde4dip"
                     /inference="alignment:Splign:2.1.0"
     exon            6429..6662
                     /gene="Pde4dip"
                     /inference="alignment:Splign:2.1.0"
     exon            6663..6782
                     /gene="Pde4dip"
                     /inference="alignment:Splign:2.1.0"
     exon            6783..7003
                     /gene="Pde4dip"
                     /inference="alignment:Splign:2.1.0"
     exon            7004..7147
                     /gene="Pde4dip"
                     /inference="alignment:Splign:2.1.0"
     exon            7148..7286
                     /gene="Pde4dip"
                     /inference="alignment:Splign:2.1.0"
     exon            7287..7333
                     /gene="Pde4dip"
                     /inference="alignment:Splign:2.1.0"
     exon            7334..8353
                     /gene="Pde4dip"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gatcatagct agggcgcagt gcccaggcct cggatccatg aagcgcacgg acagcgggtc
       61 catctgtcac cacgcgccgc cgccgtgctg ggctcaccac gcacctcgcc agtctccacg
      121 gcagccctcc agccgggaac gacgaccccc agagcgggct gggagctggg cggtggcagc
      181 agaggaggag gaggcagtct cgtcggcacc ctggatgaga cattattttg gagaagaaga
      241 tggagagatg gtgcccagaa caagcaatgc agcagctttt ctcagcgaca ctaaagatcg
      301 cggtcctccg gttcagtcgc aggtctggag aagtgccgag aaggtcccct ttgggcaggc
      361 acactccttg agagcatttg agaagccccc tctggtgcag acccaggctc ttcgagactt
      421 tgagaagcac ctcaatgacc tgaagaagga gaacttcagc ctcaagctgc gcatctactt
      481 cctggaggag cgcatgcaac agaagtatga agtcagccgg gaggacgtct acaagcggaa
      541 cattgagctg aaggttgaag tggagagcct gaaacgagag ctccaggaca ggaaacagca
      601 tctacataaa acatgggccg atgaggagga tctcaacagc cagaatgaag cagagctccg
      661 gcgccaggtt gaagaaccgc agcaggagac agaacacgtt tatgagctcc tagacaacaa
      721 cattcagctg ctgcaggagg aatccaggtt tgcaaaggat gaagccacac agatggagac
      781 tctggtggag gcagagaagg ggtgtaatct ggagctctca gagaggtgga aggatgctac
      841 caagaacagg gaagatgcac cgggagacca ggtgaagctt gaccaatatt ctgcggcact
      901 ggctcagagg gacaggagaa ttgaagagct gaggcagagc ttggctgccc aggaggggct
      961 tgtggaacag ctgtctcgag agaaacaaca actgttacat ctgctggagg agcctggggg
     1021 catggaagtg cagcccatgc ctaaagggtt acccacgcaa caaaagccag acctaaatga
     1081 gacccctaca acccagccat ctgtgtctga ttcccacctg gcagaactcc aggacaaaat
     1141 ccagcaaaca gaggtcacca acaagattct tcaagagaaa ctgaatgaca tgagctgtga
     1201 gctcagatct gcacaggagt cgtctcagaa gcaagatacg acaatccaaa gcctcaagga
     1261 aatgctaaag agcagggaaa gtgagactga ggagctgtac caggtgattg aaggtcaaaa
     1321 tgacacaatg gcaaagcttc gggaaatgct acaccagagc cagctcggac agctccagag
     1381 ctcagagggc attgcccctg ctcagcagca agtggccctg cttgaccttc agagtgctct
     1441 gttctgcagc cagcttgaaa tccagaagct ccagaggctg ttacgccaga aagagcgtca
     1501 gctggctgac ggcaagcggt gcatgcaatt tgtggaggct gcagcacagg agagagagca
     1561 gcagaaggaa gctgcttgga aacataacca ggaattacga aaagctttgc aacacctcca
     1621 aggagaactg cacagtaaga gccaacagct ccacgttctg gaggcagaaa aatataatga
     1681 aattcgaacc cagggacaaa acattcaaca cctaagtcac agtctgagtc acaaagagca
     1741 gctaattcag gaacttcagg agctcctaca gtatcgggat accacagaca aaactctaga
     1801 cacaaatgag gtgtttcttg agaaactacg gcaacgaata caagaccggg cagttgctct
     1861 agagcgggtt atagatgaaa agttctctgc tctagaagaa aaggacaagg aactgcggca
     1921 gctccggctt gctgtgaggg accgagacca tgacttagag agactgcgtt gtgtcctgtc
     1981 tgccaatgaa gctaccatgc aaagtatgga gagtctcctg agggccagag gcctggaagt
     2041 ggagcagtta actgccacct gccaaaacct ccagtggctg aaggaagaat tggaaaccaa
     2101 gtttggccac tggcagaagg aacaggagag catcattcag cagttacaga catctctgca
     2161 tgacaggaac aaagaagtag aggatctcag cgcaactttg ctccacaaac ttggacccgg
     2221 ccagagtgaa gtagctgagg agctgtgcca gcgcctgcag cggaaggaaa gggtgctgca
     2281 ggaccttctg agtgatcgga acaaacaagc catggagcac gagatggagg tccagggact
     2341 gctccagtcg atgggcaccc gggaacagga aagacaggct gttgcagaaa aaatggtaca
     2401 agccttcatg gaaagaaact cggaattaca ggccctgcgg cagtatctag gggggaagga
     2461 attaatggca gcatctcagg cattcatctc taaccaacca gctggagcga cttctgtagg
     2521 cccccaccat ggagagcaaa ctgaccaagg ttctacgcag atgccctctc gagacgacag
     2581 cacctcgctg actgccagag aggaggccag cataccccgg tctacattag gagactcaga
     2641 cacagttgca gggctggaga aagaactgag caatgccaag gaggagcttg agctcatggc
     2701 caaaaaagaa agagaaagcc agatagaatt gtctgccctg cagtccatga tggctgtgca
     2761 agaggaagag ctgcaggtgc aggctgctga cttggagtcc ctgaccagga acatacagat
     2821 aaaagaagac ctcataaagg acctgcaaat gcaactggtt gaccctgaag atatgccagc
     2881 catggagcgc ctgacccaag aggtcttact tcttcgggaa aaagttgctt cagtggaacc
     2941 ccagggtcag gaagggtcag agaacaggag acaacagttg ctgctgatgt tagaaggact
     3001 agtggatgaa cggagtcggc tcaacgaggc cctgcaagct gagcggcagc tctacagcag
     3061 cctggtcaag ttccatgccc aaccagagac ctctgagaga gaccgaactc tgcaggtgga
     3121 actggaaggg gcccaggtgt tacgcagtcg actagaagaa gttcttggaa gaagcctgga
     3181 gcgcttaagc aggctggaga ccctggctgc cattggaggt gctactgcag gcgatgagac
     3241 tgaagataca agcacacagt tcacagacag cattgaggag gaggctgcac acaacagcca
     3301 ccagcaactc atcaaggtgt ctttggagaa aagcctgacc accatggaga cccagaacac
     3361 atgtcttcag cccccttccc cagtaggaga ggatggtaac aggcatcttc aggaggaaat
     3421 gctccacctg agggctgaaa tccaccagca cttagaggag aagagaaaag ctgaggcaga
     3481 actcaaggag ctaaaggctc aaattgagga agcaggattc tcctctgtgt cccacatcag
     3541 gaacaccatg ctgagccttt gccttgagaa tgcagagctg aaagagcaga tgggagaagc
     3601 aatgtctgat ggatgggagg tggaggaaga caaggagaag ggcgaggtga tggtggagac
     3661 cgtggtggcc aaagggggtc tgagtgagga cagccttcag gctgagttca ggaaagtcca
     3721 ggggagactc aagagtgcct acaacatcat caacctcctc aaagagcagc tggtcctgag
     3781 aagctcggaa gggaacacta aggagatgcc agagttcctc gtgcgcctgg ccagggaggt
     3841 ggacagaatg aacatgggct tgccttcctc ggagaagcat caacaccaag aacaggagaa
     3901 tatgaccgca aggcctggcc ccaggcccca gagtctcaag cttgggacag ctctctcagt
     3961 agacggctac caactggaga acaagtccca ggcccaagac tctggacatc agccacaatt
     4021 tagcctacca gggtccacca aacacctgcg ctcccagctg gctcagtgta gacaacggta
     4081 ccaagatctc caggagaagc tgctcatctc agaagccact gtgtttgccc aggcaaacca
     4141 gctagagaag tacagagcca tattaagtga atccctggtg aagcaggaca gcaagcagat
     4201 ccaggtggac cttcaggacc tgggctatga gacttgtggc cgaagtgaga atgaagctga
     4261 acgtgaggag accaccagcc ctgagtgtga ggagcacggt aacctgaggc ctgtggtgct
     4321 ggtggagggc ttgtgctctg agcaggggta cctggaccct gtcttggtca gctcacctgt
     4381 gaagaagccc ttggagaaca agccagggaa gcgagaggag ttccaggcac aaggaacttc
     4441 agacgacagc tctctcctga ggaaggacat ccgagatctg aaagcccagc tacagaatgc
     4501 ctacaaggtc attcagaacc tgaggagccg ggtccggtcc ctgtctgcca caagcgatta
     4561 ctcatcgagt ctggagagac cccgcaagct gagagccgtg gcaacccttg agggggcctc
     4621 accccacagt gtcactgatg aagacgaggg ctggttgtca gatggcaccg gggcttttta
     4681 ccctccaggg ctccaggcca aaaagaatct agagaatctc atccagagag tatcccagct
     4741 ggaggcccag ctccccaaaa ctggactaga ggggaagctg gctgaggagc tgaggtccgc
     4801 ctcgtggcct ggaaaatacg attctttgat tcaggatcag gcccgagaac tgtcatatct
     4861 gcgtcagaaa atacgagaag ggagagggat ttgttatctt ctcacccaac attcgaaaga
     4921 tacagtcaaa tcttttgagg acctcctgag gagcaacgac attgactact acctgggcca
     4981 gagcttccgg gagcaactag ctcaaggcgg tcagctgaca gacaggctga ccagcaaact
     5041 cagcacaaag gatcataaga gtgaaaaaga agaagctggg cttgagccac tggccctcag
     5101 gctcagcagg gaactacagg agaaagagaa agtgattgaa gtcctgcagg ccaagctgga
     5161 tacccggtct ctctcacccc ccagcagcca tgctgcgtct gactcccacc gctctgccag
     5221 cagcacatcc ttcctgtcgg atgacataga agcctgctct gacatggacg tagccagcga
     5281 gtacacacac tatgaagaga agaagccctc acccagtaac tcagcagcca gtgcatctca
     5341 ggggcttaag ggcgagccca gaagcagctc catcagcttg ccaactcccc agaacccccc
     5401 taaggaggcc agccaggccc agccaggctt tcactttaac tccataccca agccggctag
     5461 cctttcccag gcaccaatgc acttcactgt acccagcttc atgcctttcg gcccctctgg
     5521 gcctcccctt cttggttgct gtgagacacc agtggtgtcc ttggctgagg ctcaacaaga
     5581 gctgcagatg ctgcagaagc agctgggaga aagtgttagc attgcccctc ccacctccac
     5641 atccacgttg cttagcaacc acacagaagc tagctctccc cgctacagca accctgctca
     5701 gccccactcc ccagcaaggg gcaccataga gctgggcaga atcctggagc ctggatacct
     5761 gggcagcggc cagtgggaca tgatgaggcc tcagaaaggg agcatctctg gggagctgtc
     5821 ctcaggctcc tcgatgtacc agcttaactc caaacccaca ggggccgacc tgttggaaga
     5881 gcatttaggt gagatccgga acctgcgcca gcgcctggag gagtccatat gtgtcaatga
     5941 caggctacgg gagcagctgc agcataggct cagctccacg gcccgagaaa atggttccac
     6001 ctctcacttc tacagtcagg gcctggagtc catgcctcag ctctacaatg agaacagagc
     6061 cctcagggaa gaaaaccaaa gcctgcagac acggctcagt catgcttcca ggggacactc
     6121 ccaggaagtg gaccacctga gggaggctct gctttcctca agttcccagc tccaggagct
     6181 ggagaaggag ctggagcagc agaaggctga gcggcggcag cttctggaag acttgcagga
     6241 gaagcaggat gagatcgtgc atttccgaga ggagaggctg tccctccagg aaaacaactc
     6301 caggctgcag cacaagctgg ccctcctgca acaacagtgt gaggagaaac agcagctctc
     6361 cctgtccctg cagtcagagc tccagatcta cgagtccctc tacgaaaatc ctaagaaggg
     6421 cttgaaagcc ttcagcctag attcctgtta ccaagtcccg ggtgagttga gctgcctggt
     6481 ggcagagatt cgagctctga gagtgcagtt ggagcagagc attcaagtga acaaccgtct
     6541 gcggctgcag ctggaacagc agatggatca cggtgctggc aaagccagtc tcagttcctg
     6601 ccctgttaac cagagcttct cagccaaggc ggagctggca aaccagcagc cacccttcca
     6661 aggttcagct gcttcccctc cagtccggga cgttggcttg aattctccag ccgtggtcct
     6721 ccccagcaat tcgtgctctg ttcctggctc agactctgcc atcatcagta ggacaaacaa
     6781 tggttcggat gagtctgcag caacgaagac ccctcccaag atggaggtcg atgctgctga
     6841 tggcccattt gccagtggac acggcagaca cgtcatcggc catgtggatg actacgacac
     6901 cctacagcag cagattgggg aagggaagct gctgatccaa aagatactgt ctctcacgag
     6961 gccagcacgc agcgtccctg cactggacgc gcagggcaca gaggcaccag gtaccaaaag
     7021 tgtccatgag cttcggagca gcgccagggc tctgaaccac agcctagaag agtcagcttc
     7081 cctcctcacc atgttctgga gagcagcttt gccaaactct catggttctg tactggtagg
     7141 cgaagaggga aaactgatgg agaaagaact cctagacctg cgagcccaag tgtcccaaca
     7201 gcaacagctc cttcagagca ctgctgtgcg tctgaagacg gccaaccaga ggaagaaaag
     7261 catggagcag ttcatcgtga gccatctgac caggacccat gatgtcttga agaaagcacg
     7321 gactaattta gagatgaaat ccttcagggc cctgatgtgc actccagcct tgtgaccctt
     7381 gccttccagg agccacataa aaggcgaagc caggagtcct taaaacagca ggaagggtgg
     7441 gcctgcccgc ccctagtaca gctgcctgtc tgctgaggaa tacctggtcc gactcctccc
     7501 ctgctggagc tccacggaag ggctcagaga tgtgtccaca tgggacaggc aggaaggaaa
     7561 gtggcatcct gacaatgaat atgattagcc aaggcccact gggcccagca ctaagcaaaa
     7621 ctcatgtaga ctgtgtagaa ggccccccgg cactgcttct agacagcctc agcagcacgg
     7681 tgcccacctc gttacagttc tcacctcagt atctgtcctc aagatagcca actcagggga
     7741 actaggacct taccacccac aaacaggatg tatggtccca atgccaacgc tcctcagaca
     7801 gttgtaaaag cacacatcat tgagtggcag cgtccagccg gacactgttg gagactacca
     7861 aacccctcac tgacccagtc ttgggccagg ccagctctgt gggccaagtc tggtagtact
     7921 ttggtctcta ccaccacacc agagagagtc tatatagcaa atgtggtaac ttgtaggtgc
     7981 cctgcactta gcctagcacc ttctgtttct tacgtgatct caagttgaac caacttcctt
     8041 aactctgctg tcccctgtaa tcctaacttc cctcagggga attggagact ggtggccaca
     8101 tcatgcctat tgaatgtcta gtgaacagca tatcggtgcc tcttaatggc atgggcaagg
     8161 cctgctctgt actgaagact gtgtcttcac agtgctcata ggacgtgggt gtgtgtataa
     8221 atgtataata tagatttata tatgtcgcta tggctatgtg ttgaaggcca gcataatgtg
     8281 cagagcgatg ggtgagaaga cgctaagcag tctttcttat ggctattaaa gctaactgtg
     8341 tataaagaaa tta
//
