LOCUS       NM_001025709            1784 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus phosducin-like 3 (Pdcl3), mRNA.
ACCESSION   NM_001025709 XM_237079
VERSION     NM_001025709.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1784)
  AUTHORS   Krzemien-Ojak,L., Goral,A., Joachimiak,E., Filipek,A. and
            Fabczak,H.
  TITLE     Interaction of a Novel Chaperone PhLP2A With the Heat Shock Protein
            Hsp90
  JOURNAL   J Cell Biochem 118 (2), 420-429 (2017)
   PUBMED   27496612
  REMARK    GeneRIF: results have shown that PhLP2A interacts with Hsp90 and
            exhibits molecular chaperone activity toward denatured proteins.
REFERENCE   2  (bases 1 to 1784)
  AUTHORS   Srinivasan,S., Chitalia,V., Meyer,R.D., Hartsough,E., Mehta,M.,
            Harrold,I., Anderson,N., Feng,H., Smith,L.E., Jiang,Y.,
            Costello,C.E. and Rahimi,N.
  TITLE     Hypoxia-induced expression of phosducin-like 3 regulates expression
            of VEGFR-2 and promotes angiogenesis
  JOURNAL   Angiogenesis 18 (4), 449-462 (2015)
   PUBMED   26059764
REFERENCE   3  (bases 1 to 1784)
  AUTHORS   Srinivasan,S., Meyer,R.D., Lugo,R. and Rahimi,N.
  TITLE     Identification of PDCL3 as a novel chaperone protein involved in
            the generation of functional VEGF receptor 2
  JOURNAL   J Biol Chem 288 (32), 23171-23181 (2013)
   PUBMED   23792958
REFERENCE   4  (bases 1 to 1784)
  AUTHORS   Stirling,P.C., Srayko,M., Takhar,K.S., Pozniakovsky,A., Hyman,A.A.
            and Leroux,M.R.
  TITLE     Functional interaction between phosducin-like protein 2 and
            cytosolic chaperonin is essential for cytoskeletal protein function
            and cell cycle progression
  JOURNAL   Mol Biol Cell 18 (6), 2336-2345 (2007)
   PUBMED   17429077
REFERENCE   5  (bases 1 to 1784)
  AUTHORS   Wilkinson,J.C., Richter,B.W., Wilkinson,A.S., Burstein,E.,
            Rumble,J.M., Balliu,B. and Duckett,C.S.
  TITLE     VIAF, a conserved inhibitor of apoptosis (IAP)-interacting factor
            that modulates caspase activation
  JOURNAL   J Biol Chem 279 (49), 51091-51099 (2004)
   PUBMED   15371430
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC099162.1.
            
            On Jul 22, 2005 this sequence version replaced XM_237079.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC099162.1, FQ211568.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132262
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1784
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="9"
                     /map="9q22"
     gene            1..1784
                     /gene="Pdcl3"
                     /note="phosducin-like 3"
                     /db_xref="GeneID:316348"
                     /db_xref="RGD:1309663"
     exon            1..83
                     /gene="Pdcl3"
                     /inference="alignment:Splign:2.1.0"
     CDS             78..800
                     /gene="Pdcl3"
                     /codon_start=1
                     /product="phosducin-like protein 3"
                     /protein_id="NP_001020880.1"
                     /db_xref="GeneID:316348"
                     /db_xref="RGD:1309663"
                     /translation="MQDPNADTEWNDILRKKGILPPKESLKELEEEEEGKEEQRLQQS
                     VVKTYEDMTLEELQENEDEFSEEDERAIEMYRQQRLAEWKATQLRNKFGEVLEISGKD
                     YVQEVTKAGEGLWVVLHLYKQGIPLCSLINHHLSGLARKFPDVKFIKAISTTCIPNYP
                     DRNLPTVFVYREGDIKAQFIGPLVFGGMNLTIDELEWKLSESGAIKTELEENPKKAIK
                     DVLLSSVRDPVPMRRDSDSEDD"
     exon            84..213
                     /gene="Pdcl3"
                     /inference="alignment:Splign:2.1.0"
     exon            214..304
                     /gene="Pdcl3"
                     /inference="alignment:Splign:2.1.0"
     exon            305..448
                     /gene="Pdcl3"
                     /inference="alignment:Splign:2.1.0"
     exon            449..657
                     /gene="Pdcl3"
                     /inference="alignment:Splign:2.1.0"
     exon            658..1746
                     /gene="Pdcl3"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ccgaaggggc ggtgctacaa ggcgccagag gagcggaggc tggggcctag gggctggtcg
       61 gaacttctgg aagcaagatg caggacccca acgcagacac cgagtggaat gacatccttc
      121 gtaaaaaggg catccttccc cctaaggaga gcctgaagga gctggaggag gaggaggagg
      181 gaaaggagga gcagcgtctc cagcagtcag tggtgaagac atatgaagac atgaccctgg
      241 aggagctgca ggagaacgaa gacgagttca gtgaggagga cgagcgagcc atcgagatgt
      301 accggcagca aaggctggcc gagtggaagg cgactcagct gaggaacaag tttggagaag
      361 ttttagagat ctcggggaag gattacgttc aagaagtcac caaggctggc gagggcttgt
      421 gggtggtctt acacctgtac aaacaaggga ttcccctctg ttccttgata aaccatcact
      481 tgagtgggct cgccaggaag tttcccgatg tgaaatttat caaagccatt tcaacgacct
      541 gcatacccaa ttaccctgac aggaacctcc ccacagtgtt cgtctaccgg gagggggata
      601 tcaaggcaca gttcatcggt cccctggtgt tcggtggcat gaacctgacc atagatgagt
      661 tggagtggaa actatctgag tcaggagcaa tcaagacaga gctggaggag aaccccaaga
      721 aagccatcaa agacgtgctg ctgtcctcag tgcgggaccc tgtccccatg aggagggaca
      781 gtgattccga ggacgactaa gatagcagtg atgcagcctt tcgaactctc ttgataagac
      841 gcattgtctg gagtttcaat aaggagggaa aagcaataat ttatcctttt gggttttaac
      901 ctttttataa ttatttaaat tttatacatt tcagatataa tcattgctga aattttttaa
      961 gaaatttgtt ggaactcttt ataatgtttc tttaagaatt taagctctta tgtcacatat
     1021 ccatgttttc ctacatgtgt ttcagcaaac cctgtgactg tttagtatct tttgacatgc
     1081 aactatagag aaaggaatgt ggagtttaaa aacacaatgc aaataaatta agttaaaaac
     1141 taaaacataa cagtgcagaa aacaagaact cggctttata gttaagtcag actgtccatt
     1201 ttcattttat aaagctagca aaagaaatat cagctgatag aaatggctga taattttgag
     1261 acaaatactg tcttatcaaa ctagctgaca gatttcagct tacaccatgt ttgtattcag
     1321 gtcagtcttc cagttaactc acgtgtgtct ctggctgtta agacaccagc tgttctttgt
     1381 ggtggcacat gcttttaatc ccagcactgg gacacaggca ggcaggtcat gtgagttcaa
     1441 ggctggtctg gcttgcaggg ccagggccac ctcaccaaga ccctgtcttg aagccaaaaa
     1501 cagagctgtt cttggctcta aggtcctgtt aggttcggct tgggggactg aggtttaagc
     1561 acacacacat gtaagctgtg tcccagctga tttataaaaa tgtttcggga tactctttga
     1621 gtcagaatcc tataaattga tgatgaaagc tgaaaagtat caataatatt tttgttgaat
     1681 gtggtaacat gtatagctga ttggaacctt agagataaga gtctaagaat acaggatttg
     1741 ttcagaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaa
//
