LOCUS       NM_001395615            2243 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus PEST proteolytic signal containing nuclear
            protein (Pcnp), transcript variant 1, mRNA.
ACCESSION   NM_001395615 XM_006248241
VERSION     NM_001395615.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2243)
  AUTHORS   Mori,T., Li,Y., Hata,H. and Kochi,H.
  TITLE     NIRF is a ubiquitin ligase that is capable of ubiquitinating PCNP,
            a PEST-containing nuclear protein
  JOURNAL   FEBS Lett 557 (1-3), 209-214 (2004)
   PUBMED   14741369
REFERENCE   2  (bases 1 to 2243)
  AUTHORS   Mori,T., Li,Y., Hata,H., Ono,K. and Kochi,H.
  TITLE     NIRF, a novel RING finger protein, is involved in cell-cycle
            regulation
  JOURNAL   Biochem Biophys Res Commun 296 (3), 530-536 (2002)
   PUBMED   12176013
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000011.1.
            
            On Jul 22, 2021 this sequence version replaced XM_006248241.4.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26360181.1603019.1,
                                           SRR26360186.641955.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-105               JAXUCZ010000011.1  58061885-58061989
            106-320             JAXUCZ010000011.1  58067700-58067914
            321-395             JAXUCZ010000011.1  58070160-58070234
            396-451             JAXUCZ010000011.1  58073393-58073448
            452-2243            JAXUCZ010000011.1  58074645-58076436
FEATURES             Location/Qualifiers
     source          1..2243
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="11"
                     /map="11q12"
     gene            1..2243
                     /gene="Pcnp"
                     /gene_synonym="Ab2-416"
                     /note="PEST proteolytic signal containing nuclear protein"
                     /db_xref="GeneID:288165"
                     /db_xref="RGD:1563775"
     exon            1..105
                     /gene="Pcnp"
                     /gene_synonym="Ab2-416"
                     /inference="alignment:Splign:2.1.0"
     CDS             42..578
                     /gene="Pcnp"
                     /gene_synonym="Ab2-416"
                     /note="isoform 1 is encoded by transcript variant 1;
                     PEST-containing nuclear protein; liver
                     regeneration-related protein LRRG084"
                     /codon_start=1
                     /product="PEST proteolytic signal-containing nuclear
                     protein isoform 1"
                     /protein_id="NP_001382544.1"
                     /db_xref="GeneID:288165"
                     /db_xref="RGD:1563775"
                     /translation="MADGKAGEEKPEKPQRAGAAGGPEEEAEKPVKTKTVSSSNGGES
                     SSRSAEKRSAEDEAADLPTKPTKMSKFGFAIGSQTARKASAISIRLGASKPKETVPTL
                     APKTLSVAAAFNEDEDSEPEEMPPEAKMRMKNIGRDTPTSAGPNSFNKGKHGFSDNQK
                     LWERNIKSHLGNVHDQDN"
     exon            106..320
                     /gene="Pcnp"
                     /gene_synonym="Ab2-416"
                     /inference="alignment:Splign:2.1.0"
     exon            321..395
                     /gene="Pcnp"
                     /gene_synonym="Ab2-416"
                     /inference="alignment:Splign:2.1.0"
     exon            396..451
                     /gene="Pcnp"
                     /gene_synonym="Ab2-416"
                     /inference="alignment:Splign:2.1.0"
     exon            452..2243
                     /gene="Pcnp"
                     /gene_synonym="Ab2-416"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gttcttgccc ggactgcaag ggggaggccg cggcggggaa gatggcggac gggaaggcgg
       61 gagaggagaa gcccgagaag ccgcagcgag ccggagccgc cggaggacct gaagaagaag
      121 cagaaaaacc tgtgaaaact aagactgttt cttccagtaa tggaggggaa agttccagtc
      181 gcagcgctga aaagcgatca gctgaagacg aagctgcaga cctcccaaca aagcctacaa
      241 agatgtccaa gtttggattt gccataggta gtcagacagc aaggaaagca tccgccatct
      301 ccattagact cggagcaagt aagcctaagg aaacagttcc aactcttgct ccaaaaactc
      361 tttcagtagc agcagctttc aatgaagatg aagatagtga gccggaagaa atgcctccag
      421 aagcgaagat gaggatgaag aacatcggaa gggacacgcc aacatcagcc ggaccaaact
      481 cctttaataa aggaaagcat ggcttttccg ataaccagaa gctgtgggag cgaaatatca
      541 aatctcatct tggaaacgtc cacgaccaag acaattaaga gaagtgttct gagattgggg
      601 tgtgggcggg tgcattagaa ggagcagtca gcctcctttt tgtaaagaat ggtgtaagac
      661 tagctttgga gccgtttttc tttcttcttt tttcttttcc ttttttcttt tttttttttt
      721 aagattgagt ggtacactaa taaatgagag tttgcaatta gaggtaattt atgttttata
      781 tacagatttc aagacatttg ctaattttgt agtttcacat gattagtttc caagggttac
      841 agataataaa gaaatcagaa gtggtacctt tctaagaatt gcatattttt ttagacacaa
      901 ctattagcac attaagaggg aagccaaaag ttattgccta cttcaaagtg aaagcagttc
      961 ctctcctgac ttctccccca cattacctga ctgtctgtct ggctccctgg aacagcctta
     1021 cgagagggaa ttggattgag aagacaattg ttactggact attgactgaa agtaaattta
     1081 gatacaatta aaataaacct tttcctatgg gcatttcacc ttgttctggg ccattatatg
     1141 ctagtactgc ttcgctatca gtacagacgc tttgctcttt aaaaactttt ttcgttaaaa
     1201 attcttgtat gaagtattga gtattataac tagcccactt taatggaggt tgtctccctt
     1261 caggattctt caaaggacac tatttgctac caaagtgaat cagtatttga atgtgcttct
     1321 cttggtttct attctagttc ctataatcat ttccaccaga acttgaggca agacataagg
     1381 aagctgtttc ttttaaagta caaaccgctg aaaacatcag tgtgcgcact gcttaagtat
     1441 ttggctggct tttatttttt aaaaggttta aataccaaaa gaggaaaagg gtgtaacgtg
     1501 gtgtgaagac aggtgaggca gctcacccgt gacttttgaa gcatttaagt tactgactta
     1561 ctagatccag ttttgaactg aattcacacg atttcttatt tgtacaactc catggtttat
     1621 tttaagtatg tacatactga gcagtggttt caaaagcaca tttagtgact gaaatgggac
     1681 agaaatgctt cttcagacac actttcattg tgagtctctc atcgcatatg ctcttagatt
     1741 tctgtatcta gggtgtttgt tttgtatttt ttgtatcgta tatgggcttt ttaaacgtga
     1801 cagttaatgc atctttaata gtcacagact aaagaaatga taaaatgtcc ttgaaaatga
     1861 caatgttaag tttggaggcg gcttgggtga gtttcatggg tggtgatgat tcactaggca
     1921 atttttactg taatgacttc cgagaagcag cctgcgggtg tacctgacac gttcactaca
     1981 ttgagtccac ttagtaagcc cgagtacacg atgggaatgt acattagcac tattagttca
     2041 tacatgattt aagtatatca agatacatac atttaccttt tacgtctgca aactgtcctg
     2101 tggccatttt actgtttgtt gaaataacac ctctcctaca tgttctttac ttgactggaa
     2161 gaacagttaa cctgaggtca agatggagag acgactaagc taagtgtctt tactaaaact
     2221 acaataaatt ttgtcaaact tgg
//
