LOCUS       NM_001013154            2110 bp    mRNA    linear   ROD 02-JUN-2024
DEFINITION  Rattus norvegicus polycomb group ring finger 6 (Pcgf6), mRNA.
ACCESSION   NM_001013154 XM_219963
VERSION     NM_001013154.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2110)
  AUTHORS   Almeida,M., Pintacuda,G., Masui,O., Koseki,Y., Gdula,M., Cerase,A.,
            Brown,D., Mould,A., Innocent,C., Nakayama,M., Schermelleh,L.,
            Nesterova,T.B., Koseki,H. and Brockdorff,N.
  TITLE     PCGF3/5-PRC1 initiates Polycomb recruitment in X chromosome
            inactivation
  JOURNAL   Science 356 (6342), 1081-1084 (2017)
   PUBMED   28596365
REFERENCE   2  (bases 1 to 2110)
  AUTHORS   Taherbhoy,A.M., Huang,O.W. and Cochran,A.G.
  TITLE     BMI1-RING1B is an autoinhibited RING E3 ubiquitin ligase
  JOURNAL   Nat Commun 6, 7621 (2015)
   PUBMED   26151332
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 2110)
  AUTHORS   Gil,J. and O'Loghlen,A.
  TITLE     PRC1 complex diversity: where is it taking us?
  JOURNAL   Trends Cell Biol 24 (11), 632-641 (2014)
   PUBMED   25065329
  REMARK    Review article
REFERENCE   4  (bases 1 to 2110)
  AUTHORS   Simon,J.A. and Kingston,R.E.
  TITLE     Occupying chromatin: Polycomb mechanisms for getting to genomic
            targets, stopping transcriptional traffic, and staying put
  JOURNAL   Mol Cell 49 (5), 808-824 (2013)
   PUBMED   23473600
  REMARK    Review article
REFERENCE   5  (bases 1 to 2110)
  AUTHORS   Vandamme,J., Volkel,P., Rosnoblet,C., Le Faou,P. and Angrand,P.O.
  TITLE     Interaction proteomics analysis of polycomb proteins defines
            distinct PRC1 complexes in mammalian cells
  JOURNAL   Mol Cell Proteomics 10 (4), M110.002642 (2011)
   PUBMED   21282530
REFERENCE   6  (bases 1 to 2110)
  AUTHORS   Maertens,G.N., El Messaoudi-Aubert,S., Racek,T., Stock,J.K.,
            Nicholls,J., Rodriguez-Niedenfuhr,M., Gil,J. and Peters,G.
  TITLE     Several distinct polycomb complexes regulate and co-localize on the
            INK4a tumor suppressor locus
  JOURNAL   PLoS One 4 (7), e6380 (2009)
   PUBMED   19636380
  REMARK    Publication Status: Online-Only
REFERENCE   7  (bases 1 to 2110)
  AUTHORS   Akasaka,T., Takahashi,N., Suzuki,M., Koseki,H., Bodmer,R. and
            Koga,H.
  TITLE     MBLR, a new RING finger protein resembling mammalian Polycomb gene
            products, is regulated by cell cycle-dependent phosphorylation
  JOURNAL   Genes Cells 7 (8), 835-850 (2002)
   PUBMED   12167161
REFERENCE   8  (bases 1 to 2110)
  AUTHORS   Kanno,M., Hasegawa,M., Ishida,A., Isono,K. and Taniguchi,M.
  TITLE     mel-18, a Polycomb group-related mammalian gene, encodes a
            transcriptional negative regulator with tumor suppressive activity
  JOURNAL   EMBO J 14 (22), 5672-5678 (1995)
   PUBMED   8521824
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC083820.1.
            
            On Apr 20, 2005 this sequence version replaced XM_219963.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC083820.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760434
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..2110
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q54"
     gene            1..2110
                     /gene="Pcgf6"
                     /gene_synonym="Rnf134"
                     /note="polycomb group ring finger 6"
                     /db_xref="GeneID:309457"
                     /db_xref="RGD:1306904"
     exon            1..417
                     /gene="Pcgf6"
                     /gene_synonym="Rnf134"
                     /inference="alignment:Splign:2.1.0"
     CDS             55..1110
                     /gene="Pcgf6"
                     /gene_synonym="Rnf134"
                     /note="ring finger protein 134"
                     /codon_start=1
                     /product="polycomb group RING finger protein 6"
                     /protein_id="NP_001013172.1"
                     /db_xref="GeneID:309457"
                     /db_xref="RGD:1306904"
                     /translation="MEEAETDATENKRASEAKRASAMLPPPPPPISPPALIPAPAAGE
                     EGPASLAQAGAPGCSRSRPPELEPERSLGRLRGRFEDYDEELEEDEEMEEEEEEEEEM
                     SHFSLRLESGRADSEDEEERLINLVELTPYILCSICKGYLIDATTITECLHTFCKSCI
                     VRHFYYSNRCPKCNIVVHQTQPLYNIRLDRQLQDIVYKLVVNLEEREKKQMHDFYKER
                     GLEVPKPAVPQPVPASKGRTKKALESVFRIPPELDVSLLLEFIGANEDTGHFKPLEKK
                     FVRVSGEATIGHVEKFLRRKMGLDPACQVDIICGDHLLERYQTLREIRRAIGDTAMQD
                     GLLVLHYGLVVSPLKIT"
     exon            418..614
                     /gene="Pcgf6"
                     /gene_synonym="Rnf134"
                     /inference="alignment:Splign:2.1.0"
     exon            615..670
                     /gene="Pcgf6"
                     /gene_synonym="Rnf134"
                     /inference="alignment:Splign:2.1.0"
     exon            671..730
                     /gene="Pcgf6"
                     /gene_synonym="Rnf134"
                     /inference="alignment:Splign:2.1.0"
     exon            731..839
                     /gene="Pcgf6"
                     /gene_synonym="Rnf134"
                     /inference="alignment:Splign:2.1.0"
     exon            840..867
                     /gene="Pcgf6"
                     /gene_synonym="Rnf134"
                     /inference="alignment:Splign:2.1.0"
     exon            868..966
                     /gene="Pcgf6"
                     /gene_synonym="Rnf134"
                     /inference="alignment:Splign:2.1.0"
     exon            967..1053
                     /gene="Pcgf6"
                     /gene_synonym="Rnf134"
                     /inference="alignment:Splign:2.1.0"
     exon            1054..2091
                     /gene="Pcgf6"
                     /gene_synonym="Rnf134"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gccaccggac tcccctcgcc tcgcgctcag ctcgcctggt ttctgatccc cgccatggag
       61 gaggctgaga cggacgccac ggaaaacaag cgcgcctctg aggccaagcg agcctcggcc
      121 atgctgccac cgcctccgcc tcccatctct ccgcccgccc tcatcccggc gccagcggcc
      181 ggtgaggagg gcccggcgtc cctggcccag gcgggcgcac ccggctgttc tcgctctcgg
      241 cccccggagt tggagcccga gcgcagcctg ggccgcttga gaggccgctt cgaggactac
      301 gatgaagagt tggaagagga tgaggagatg gaggaggagg aagaggagga ggaagagatg
      361 agccacttct ctctgcgtct ggagtccgga cgggcggact ccgaggacga ggaagagcgc
      421 ctgatcaacc tggttgagct gaccccctac atcttgtgct ccatttgcaa aggttacttg
      481 atagatgcca ccactattac agaatgtctc cacaccttct gtaaaagctg cattgtgaga
      541 catttttact atagcaacag atgccccaaa tgcaacatag tcgtccacca gactcagcct
      601 ctttataata taaggttgga ccggcagtta caagacatag tatacaaatt agtagtcaat
      661 ctagaggaaa gagaaaaaaa gcaaatgcat gacttctata aagaaagagg tctagaagtc
      721 cctaagcctg ctgttccaca gcccgtccct gcaagcaaag gaagaaccaa gaaagcccta
      781 gagtcagtgt ttcgtattcc gcctgaactt gatgtgtctt tattacttga gttcattggt
      841 gctaatgaag acacaggaca ttttaagcca ttggaaaaga agtttgtgcg tgtttcagga
      901 gaagcaacta ttgggcatgt agaaaaattt cttagaagaa aaatgggtct tgatccagct
      961 tgtcaggtag acatcatctg tggggatcac ttactggagc ggtaccaaac tctgcgggaa
     1021 atccgacgtg caataggtga cacagcaatg caggatggtc tacttgttct tcattatggt
     1081 cttgtggttt ctcctttaaa aataacttga aaatccaaga gtatattgga ggcttctgca
     1141 gatgtgcatc acaccaaaga ttctcccaga gcatgtaacc accaccactt acgctgttaa
     1201 gagctagctt ctgttcttag caccagaacc ctagcaatgt gtacaacttg aaacaataga
     1261 atgtatttgc tacactaaag actatgtaaa aaacattcat aactcagggg aaaaaactga
     1321 aaaacactga attttaaaat tccttgtgat tccaaatatg aggaagttgc tggttgcttc
     1381 ccgtccttgt tggtccttcg ggagctgggt ttctgccctc caactccaac tgcatgggtt
     1441 gggtgggtgt cctttagaac agttttgctt tgaatttaaa cctcagagtg cactcagcac
     1501 caaaactact ggccacttac atgttcctgt cctattctga acttaaaaaa attccagtga
     1561 tactactaca gcgctgttac tcagctctga gactgttaga aatggctcgc tcttcttgac
     1621 gtcccttaaa tatgaggtgc ttctttctga tggcttattt gcatctatcg gtgccactgg
     1681 gacaggtgtc acaaaagtcc ctcggtgcgg ctgttgataa tgccattgct tctaacagta
     1741 gcaaaagttt caggtgaatt accagaagtt tacataatcc tcattgtttc ttcagtcact
     1801 tagattatct ggttcgtgtt taatgttttt gttttctcgt catttggata aaaaatcaga
     1861 gtctttgaga accttgcttt tcacaaagac ttacttgtaa acattatttt gcctaaaatt
     1921 agcatcctga tgctttctaa aataaaattt tatagactta tttcatagca aaatttccaa
     1981 atctgtacag aaatttaaaa aattagactt acattggcaa ctgttttgta aagaatttat
     2041 gaattgtaca taaacctctt ctgacattta ataaaagttt attttagcca aaaaaaaaaa
     2101 aaaaaaaaaa
//
