LOCUS       NM_001007000             919 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus polycomb group ring finger 1 (Pcgf1), mRNA.
ACCESSION   NM_001007000 XM_232109
VERSION     NM_001007000.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 919)
  AUTHORS   Almeida,M., Pintacuda,G., Masui,O., Koseki,Y., Gdula,M., Cerase,A.,
            Brown,D., Mould,A., Innocent,C., Nakayama,M., Schermelleh,L.,
            Nesterova,T.B., Koseki,H. and Brockdorff,N.
  TITLE     PCGF3/5-PRC1 initiates Polycomb recruitment in X chromosome
            inactivation
  JOURNAL   Science 356 (6342), 1081-1084 (2017)
   PUBMED   28596365
REFERENCE   2  (bases 1 to 919)
  AUTHORS   Taherbhoy,A.M., Huang,O.W. and Cochran,A.G.
  TITLE     BMI1-RING1B is an autoinhibited RING E3 ubiquitin ligase
  JOURNAL   Nat Commun 6, 7621 (2015)
   PUBMED   26151332
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 919)
  AUTHORS   Gil,J. and O'Loghlen,A.
  TITLE     PRC1 complex diversity: where is it taking us?
  JOURNAL   Trends Cell Biol 24 (11), 632-641 (2014)
   PUBMED   25065329
  REMARK    Review article
REFERENCE   4  (bases 1 to 919)
  AUTHORS   Simon,J.A. and Kingston,R.E.
  TITLE     Occupying chromatin: Polycomb mechanisms for getting to genomic
            targets, stopping transcriptional traffic, and staying put
  JOURNAL   Mol Cell 49 (5), 808-824 (2013)
   PUBMED   23473600
  REMARK    Review article
REFERENCE   5  (bases 1 to 919)
  AUTHORS   Vandamme,J., Volkel,P., Rosnoblet,C., Le Faou,P. and Angrand,P.O.
  TITLE     Interaction proteomics analysis of polycomb proteins defines
            distinct PRC1 complexes in mammalian cells
  JOURNAL   Mol Cell Proteomics 10 (4), M110.002642 (2011)
   PUBMED   21282530
REFERENCE   6  (bases 1 to 919)
  AUTHORS   Van Kirk,C.A., VanGuilder,H.D., Young,M., Farley,J.A., Sonntag,W.E.
            and Freeman,W.M.
  TITLE     Age-related alterations in retinal neurovascular and inflammatory
            transcripts
  JOURNAL   Mol Vis 17, 1261-1274 (2011)
   PUBMED   21633715
REFERENCE   7  (bases 1 to 919)
  AUTHORS   Gearhart,M.D., Corcoran,C.M., Wamstad,J.A. and Bardwell,V.J.
  TITLE     Polycomb group and SCF ubiquitin ligases are found in a novel BCOR
            complex that is recruited to BCL6 targets
  JOURNAL   Mol Cell Biol 26 (18), 6880-6889 (2006)
   PUBMED   16943429
REFERENCE   8  (bases 1 to 919)
  AUTHORS   Gong,Y., Wang,X., Liu,J., Shi,L., Yin,B., Peng,X., Qiang,B. and
            Yuan,J.
  TITLE     NSPc1, a mainly nuclear localized protein of novel PcG family
            members, has a transcription repression activity related to its PKC
            phosphorylation site at S183
  JOURNAL   FEBS Lett 579 (1), 115-121 (2005)
   PUBMED   15620699
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000004.1.
            
            On Dec 3, 2020 this sequence version replaced NM_001007000.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AY662670.1, SRR26360176.2339136.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-135               JAXUCZ010000004.1  117142061-117142195
            136-241             JAXUCZ010000004.1  117142615-117142720
            242-394             JAXUCZ010000004.1  117142818-117142970
            395-466             JAXUCZ010000004.1  117143135-117143206
            467-572             JAXUCZ010000004.1  117143343-117143448
            573-606             JAXUCZ010000004.1  117143667-117143700
            607-693             JAXUCZ010000004.1  117143797-117143883
            694-774             JAXUCZ010000004.1  117144418-117144498
            775-919             JAXUCZ010000004.1  117144585-117144729
FEATURES             Location/Qualifiers
     source          1..919
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="4"
                     /map="4q34"
     gene            1..919
                     /gene="Pcgf1"
                     /gene_synonym="Nspc1"
                     /note="polycomb group ring finger 1"
                     /db_xref="GeneID:312480"
                     /db_xref="RGD:1549782"
     exon            1..135
                     /gene="Pcgf1"
                     /gene_synonym="Nspc1"
                     /inference="alignment:Splign:2.1.0"
     CDS             43..822
                     /gene="Pcgf1"
                     /gene_synonym="Nspc1"
                     /note="nervous system Polycomb-1; nervous system polycomb
                     1"
                     /codon_start=1
                     /product="polycomb group RING finger protein 1"
                     /protein_id="NP_001007001.2"
                     /db_xref="GeneID:312480"
                     /db_xref="RGD:1549782"
                     /translation="MASPQGGQIAIAMRLRNQLQSVYKMDPLRNEEEVRVKIKDLNEH
                     IVCCLCAGYFVDATTITECLHTFCKSCIVKYLQTSKYCPMCNIKIHETQPLLNLKLDR
                     VMQDIVYKLVPGLQDSEEKRIREFYQSRGLDRVSQPSGEEPALSNLGLPFSSFDHSKA
                     HYYRYDEQLSLCLERLSSGKDKNKNVLQNKYVRCSVRAEVRHLRRVLCHRLMLNPQHV
                     QLLFDNEVLPDHMTMKQLWLSRWFGKPSPLLLQYSVKEKRR"
     exon            136..241
                     /gene="Pcgf1"
                     /gene_synonym="Nspc1"
                     /inference="alignment:Splign:2.1.0"
     exon            242..394
                     /gene="Pcgf1"
                     /gene_synonym="Nspc1"
                     /inference="alignment:Splign:2.1.0"
     exon            395..466
                     /gene="Pcgf1"
                     /gene_synonym="Nspc1"
                     /inference="alignment:Splign:2.1.0"
     exon            467..572
                     /gene="Pcgf1"
                     /gene_synonym="Nspc1"
                     /inference="alignment:Splign:2.1.0"
     exon            573..606
                     /gene="Pcgf1"
                     /gene_synonym="Nspc1"
                     /inference="alignment:Splign:2.1.0"
     exon            607..693
                     /gene="Pcgf1"
                     /gene_synonym="Nspc1"
                     /inference="alignment:Splign:2.1.0"
     exon            694..774
                     /gene="Pcgf1"
                     /gene_synonym="Nspc1"
                     /inference="alignment:Splign:2.1.0"
     exon            775..919
                     /gene="Pcgf1"
                     /gene_synonym="Nspc1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gcaggcggta ccggaagtgg caggctggga tcagccttta agatggcgtc tcctcagggg
       61 ggccagattg cgatcgcgat gaggcttcgg aaccagctcc agtcagtgta caagatggac
      121 ccactacgga acgaggagga ggtccgggtg aagatcaaag acctgaatga acacatcgtt
      181 tgctgcctat gcgcgggcta cttcgtggac gccaccacta tcacagagtg cctccacacc
      241 ttctgcaaaa gttgtatcgt gaagtacctg cagaccagca agtactgccc catgtgtaac
      301 atcaagatcc acgagacgca gccgttgctc aatctcaaac tggatcgggt catgcaggac
      361 atagtgtata agctagtacc aggcttgcaa gacagtgaag agaaacggat tcgggaattc
      421 tatcagtccc gaggcttgga cagagtctcc cagcccagtg gtgaagagcc agccctgagc
      481 aaccttggcc tccccttcag cagttttgac cactctaaag cccactatta tcgatacgat
      541 gagcagctga gcctatgcct ggagcggctg agttctggca aagacaagaa taaaaatgtc
      601 cttcagaaca agtatgttcg atgttctgtt agagctgagg tccgccatct ccgaagggtt
      661 ctgtgtcacc gactaatgct aaatccacaa catgtacagc tcctttttga caatgaggtt
      721 ctccctgatc acatgacaat gaagcagcta tggctttccc gctggttcgg caagccatct
      781 cctttgcttc tacaatacag tgtgaaagag aagaggaggt aggggccagg cttgcttcca
      841 cccccttccc acccctccca gatatttatg tgaaattaac tgcggtttta ttttttgaaa
      901 taaatgcttt taaaaagca
//
