LOCUS       NM_001164288            3157 bp    mRNA    linear   ROD 21-MAR-2023
DEFINITION  Rattus norvegicus protocadherin gamma subfamily C, 5 (Pcdhgc5),
            mRNA.
ACCESSION   NM_001164288
VERSION     NM_001164288.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3157)
  AUTHORS   Li Y, Xiao H, Chiou TT, Jin H, Bonhomme B, Miralles CP, Pinal N,
            Ali R, Chen WV, Maniatis T and De Blas AL.
  TITLE     Molecular and functional interaction between protocadherin-gammaC5
            and GABAA receptors
  JOURNAL   J Neurosci 32 (34), 11780-11797 (2012)
   PUBMED   22915120
REFERENCE   2  (bases 1 to 3157)
  AUTHORS   Chen WV, Alvarez FJ, Lefebvre JL, Friedman B, Nwakeze C, Geiman E,
            Smith C, Thu CA, Tapia JC, Tasic B, Sanes JR and Maniatis T.
  TITLE     Functional significance of isoform diversification in the
            protocadherin gamma gene cluster
  JOURNAL   Neuron 75 (3), 402-409 (2012)
   PUBMED   22884324
  REMARK    Erratum:[Neuron. 2012 Sep 6;75(5):928-9]
REFERENCE   3  (bases 1 to 3157)
  AUTHORS   Wu Q.
  TITLE     Comparative genomics and diversifying selection of the clustered
            vertebrate protocadherin genes
  JOURNAL   Genetics 169 (4), 2179-2188 (2005)
   PUBMED   15744052
REFERENCE   4  (bases 1 to 3157)
  AUTHORS   Murata Y, Hamada S, Morishita H, Mutoh T and Yagi T.
  TITLE     Interaction with protocadherin-gamma regulates the cell surface
            expression of protocadherin-alpha
  JOURNAL   J Biol Chem 279 (47), 49508-49516 (2004)
   PUBMED   15347688
REFERENCE   5  (bases 1 to 3157)
  AUTHORS   Zhang T, Haws P and Wu Q.
  TITLE     Multiple variable first exons: a mechanism for cell- and
            tissue-specific gene regulation
  JOURNAL   Genome Res 14 (1), 79-89 (2004)
   PUBMED   14672974
REFERENCE   6  (bases 1 to 3157)
  AUTHORS   Johnson KJ, Patel SR and Boekelheide K.
  TITLE     Multiple cadherin superfamily members with unique expression
            profiles are produced in rat testis
  JOURNAL   Endocrinology 141 (2), 675-683 (2000)
   PUBMED   10650949
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from GQ131870.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: GQ131870.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132262
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..3157
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="Sprague-Dawley"
                     /db_xref="taxon:10116"
                     /chromosome="18"
                     /map="18p11"
     gene            1..3157
                     /gene="Pcdhgc5"
                     /note="protocadherin gamma subfamily C, 5"
                     /db_xref="GeneID:641525"
                     /db_xref="RGD:2312582"
     exon            1..2541
                     /gene="Pcdhgc5"
                     /inference="alignment:Splign:2.1.0"
     CDS             82..2916
                     /gene="Pcdhgc5"
                     /note="protocadherin gamma c5"
                     /codon_start=1
                     /product="protocadherin gamma-C5"
                     /protein_id="NP_001157760.1"
                     /db_xref="GeneID:641525"
                     /db_xref="RGD:2312582"
                     /translation="MGPMASPQVTGKRQVLYMLSLCCCGWVSGQLRYSVVEESEPGTL
                     VGNVAQDLGLKVADLLSRRLRLGSEENGRYFSLSLMSGALAVNLKIDRESLCGASTSC
                     LLPVQVVTEHPLELTRVEVEILDLNDNSPSFATPEREMRISESAAPGARFPLDSAQDP
                     DVGTNTVSFYTLSPSSHFSLNVKTLKDGKLFPELVLEQQLDREAQARHQLVLTAVDGG
                     TPARSGTSLISVIVLDINDNAPTFQSSVLRVGLPENTPPGTLLLRLNATDPDEGTNGQ
                     LDYSFGDHTSEAVKNLFGLDPNTGAIHVLGPVDFEESNFYEIHARARDQGQPAMEGHC
                     VIQVDVGDANDNPPEVLLASLVNPVLESTPVGTVVGLFNVRDRDSGRNGEVILETTPN
                     LPFQIKPSENHYSLLTSQPLDREVTSHYTIDLLASDAGSPPLHTHLTIRLNISDVNDN
                     APHFTQQLYTAYIPENRPPGSLLCTVAASDPDEGDNARLTYSIVGSQIQGAPASSFVY
                     VNPEDGRVFAQRTFDYELLQMLQIVVGVRDSGSPRLYANTSLHVFVLDQNDNAPTVLH
                     PRSGREFSAPQRLPRSAPPGSLVTKVTAVDADAGHNAWLSYSLLPQSTAPGLFLVSTH
                     TGEVRTARALLEDDSDTQQVVVLVRDNGDPSLSSTATVLLVLEDEDAEEMPKSSDFLT
                     HPPERSDLTLYLIVALAAVSLLSLVTFTFMSAKCLRRHEDRDRGGGQCCRGQDSPSRE
                     FYKQSSPNLQVSSDGTLKYMEVTLRPTDSQSHCYRTCFSPASDGSDFTFLRPLSVQQP
                     SALALEPEALRSRSSTLRERSQQAPPNTDWRFSQAQRPGTSGSQNGDETGTWPNNQFD
                     TEMLQAMILASASEAADGSSTLGGGTGTMGLSARYGPQFTLQHVPDYRQNVYIPGSNA
                     TLTNAAGKRDGKAPAGGNGNKKKSGKKEKK"
     exon            2542..2600
                     /gene="Pcdhgc5"
                     /inference="alignment:Splign:2.1.0"
     exon            2601..2689
                     /gene="Pcdhgc5"
                     /inference="alignment:Splign:2.1.0"
     exon            2690..3139
                     /gene="Pcdhgc5"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cagcttctgc actccaggct ctgggttttt accttggaga caggactgca cagttgctct
       61 ccaagaaggg acttctgggt catggggcct atggcatcac cacaggtcac tggtaaacgg
      121 caagtgctgt atatgttgtc cttgtgctgc tgtggctggg tgtctgggca gcttcgttat
      181 tcagtggtgg aggaatcaga gccggggact ttggtgggga acgttgctca agatctgggc
      241 ttaaaggtgg cagatctgtt gagtcgcagg ctgagactgg gctctgagga gaacgggcgc
      301 tatttttccc tgagcttgat gagtggagct ttggcagtga atctaaaaat tgaccgagag
      361 agcctgtgtg gagccagcac gagctgcctg ctgcctgtac aggtggtaac cgaacacccc
      421 ctggagctca cccgggtaga ggtagagatc ctagatctca acgacaactc tcctagcttt
      481 gccactcctg agcgagagat gcgcatctca gaatcagcgg cacctggagc caggttccca
      541 ctggacagtg cccaagaccc agacgtgggc accaatactg tgagctttta tactctaagc
      601 cccagcagtc acttctctct gaatgtgaag accctaaaag atgggaagct cttcccagag
      661 ctagtgctag agcagcagct agaccgggaa gcccaggcaa ggcatcagct ggtactcact
      721 gctgtggatg ggggaacccc agcccgctca gggaccagcc ttatctctgt cattgtgctg
      781 gacatcaatg ataatgcccc aaccttccag tcctcagttc tacgtgtggg actcccagag
      841 aacacacccc cggggaccct gctgctccgt ctcaatgcca ctgatccaga cgagggcacc
      901 aatggccaac tagactactc tttcggagac catacatctg aagcagtgaa gaatctcttt
      961 ggcctggatc ctaacactgg agcaatccac gtgttgggtc cggtagattt tgaggaatca
     1021 aatttctatg aaattcatgc aagagctcga gaccagggac agccagccat ggagggccac
     1081 tgtgtaatcc aggtggatgt aggggatgct aacgacaatc cccctgaggt gctgctggca
     1141 tctttggtca accctgtcct agagagcaca cccgtgggca cagttgtggg gttgtttaat
     1201 gtgcgggacc gagactcagg tagaaatggt gaggtgatcc tggagacaac tccaaacctg
     1261 ccatttcaga tcaagccttc cgagaaccat tactcactgc tcaccagcca gcctttggac
     1321 cgagaggtca catcccatta caccatcgac ctgctggcca gtgatgctgg atcacctccc
     1381 ctgcatacac atctcaccat caggctgaac atttcagatg ttaatgacaa cgcaccccat
     1441 ttcacccaac agctctacac tgcttatatc ccagaaaacc ggccaccagg ctctctcctc
     1501 tgtactgtgg ctgcctctga tccagatgag ggggataatg cccgcctcac ctattctatt
     1561 gtgggaagtc aaattcaggg agccccagcc tcctccttcg tgtatgtcaa ccccgaagat
     1621 ggacgagtct ttgcccagcg gacctttgac tatgaattac tgcagatgct gcagattgtg
     1681 gtgggggtcc gagattccgg ctctccccga ctgtatgcta acacatctct ccatgtgttt
     1741 gtccttgatc agaacgataa cgccccaact gtactgcacc cacgatctgg cagggagttc
     1801 tcagcccctc agcgtctccc ccgatctgct cctcctggtt ctctggtcac caaggtgaca
     1861 gctgtggatg ctgatgctgg tcacaatgca tggctctctt actctctatt acctcagtcc
     1921 acagcccctg gactgttcct cgtatctaca cacactggtg aggtgcgcac agcccgggcc
     1981 ttattggagg acgactctga tacccaacag gtggtggtcc tggtgaggga caatggtgac
     2041 ccttcactat cctccacagc aacagtattg ctggttctgg aggacgagga tgcagaggaa
     2101 atgcccaaat ccagcgactt cctcacacac cctcccgagc ggtcagacct caccctttat
     2161 cttattgtgg cgctggcagc tgtcagtctc ttatccctag ttaccttcac tttcatgtca
     2221 gctaagtgtc tgcggaggca tgaagatagg gaccggggtg ggggccagtg ctgcaggggc
     2281 caggactcgc cctccaggga gttctataaa cagtccagtc ccaaccttca ggtcagctca
     2341 gatggcactc taaagtacat ggaggtgacc ctgcggccca cagattctca gagccattgc
     2401 tacaggacgt gcttttctcc agcctccgat ggcagtgact tcactttcct caggcccctc
     2461 agcgttcagc agccctcagc cttggcgctg gagcccgagg ccttgcgttc ccggtctagt
     2521 acgctgcggg agcggagcca gcaagccccg cccaacactg actggcgttt ctctcaagcc
     2581 cagagacccg gcacgagcgg atcccaaaat ggggatgaaa ccggcacctg gcccaacaac
     2641 cagttcgata cagagatgct gcaagccatg atcttggcct ctgccagtga agccgctgat
     2701 gggagctcca ctctgggagg gggcactggc actatgggtt tgagcgctcg atatggaccc
     2761 cagtttaccc tgcagcacgt gcctgactac cgccagaacg tgtacatccc tggcagcaat
     2821 gccacactga ccaacgcagc tggcaaacga gatggcaagg ctccggcagg cggcaatggc
     2881 aacaagaaga agtcgggcaa gaaagagaag aagtaatatg gaggccaggc cttgagccac
     2941 agggcagcct ccctccccag ccagtccagc ttgtccttac ttgtacccag gcctcagaat
     3001 ttcagggctc accccaggat tctggtagga gccacagcca ggccatgctc cccgttggga
     3061 aacagaaaca agtgcccaag ccaacacccc ctctttgtac cctagggggg ttgaatatgc
     3121 aaagagagtt ctgctgggaa aaaaaaaaaa aaaaaaa
//
