LOCUS       NM_001037159            4714 bp    mRNA    linear   ROD 20-MAR-2023
DEFINITION  Rattus norvegicus protocadherin gamma subfamily B, 8 (Pcdhgb8),
            mRNA.
ACCESSION   NM_001037159 XM_344672
VERSION     NM_001037159.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 4714)
  AUTHORS   Zou C, Huang W, Ying G and Wu Q.
  TITLE     Sequence analysis and expression mapping of the rat clustered
            protocadherin gene repertoires
  JOURNAL   Neuroscience 144 (2), 579-603 (2007)
   PUBMED   17110050
REFERENCE   2  (bases 1 to 4714)
  AUTHORS   Wu Q.
  TITLE     Comparative genomics and diversifying selection of the clustered
            vertebrate protocadherin genes
  JOURNAL   Genetics 169 (4), 2179-2188 (2005)
   PUBMED   15744052
REFERENCE   3  (bases 1 to 4714)
  AUTHORS   Murata Y, Hamada S, Morishita H, Mutoh T and Yagi T.
  TITLE     Interaction with protocadherin-gamma regulates the cell surface
            expression of protocadherin-alpha
  JOURNAL   J Biol Chem 279 (47), 49508-49516 (2004)
   PUBMED   15347688
REFERENCE   4  (bases 1 to 4714)
  AUTHORS   Zhang T, Haws P and Wu Q.
  TITLE     Multiple variable first exons: a mechanism for cell- and
            tissue-specific gene regulation
  JOURNAL   Genome Res 14 (1), 79-89 (2004)
   PUBMED   14672974
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AY574027.1.
            
            On Nov 9, 2005 this sequence version replaced XM_344672.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AY574027.1, SRR8487231.188459.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132267, SAMD00132273
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..4714
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="18"
                     /map="18p11"
     gene            1..4714
                     /gene="Pcdhgb8"
                     /gene_synonym="Pcdhgb5"
                     /note="protocadherin gamma subfamily B, 8"
                     /db_xref="GeneID:364845"
                     /db_xref="RGD:1307432"
     exon            1..2587
                     /gene="Pcdhgb8"
                     /gene_synonym="Pcdhgb5"
                     /inference="alignment:Splign:2.1.0"
     CDS             173..2962
                     /gene="Pcdhgb8"
                     /gene_synonym="Pcdhgb5"
                     /note="protocadherin gamma subfamily B, 5; protocadherin
                     gamma-B3"
                     /codon_start=1
                     /product="protocadherin gamma-B3 precursor"
                     /protein_id="NP_001032236.1"
                     /db_xref="GeneID:364845"
                     /db_xref="RGD:1307432"
                     /translation="MERSVKLGSRTLWRQVLFPFLLPLFCTGLAEQVRYSIPEEMAMG
                     SVVGNLAEDLGLPVQDLLIRNLRVISEKPYLTVNPENGNIVVSDKIDRELLCFQSPLC
                     VLPLEIVAENPLNVFHVSVVIEDINDNPPRFLQNRIVLQINEFAIPGTRFGLESAIDA
                     DVGPNSLQSYQLSLNEHFSLVVKDKTEGKDAPELVLEKPLDREKQSSQLLVLTAVDGG
                     EPVLTGTAQIQIEVTDANDNPPVFSQSTYKVSLRENMPSGTSVLTVMATDPDEGVNAE
                     ITYSFKSLGEDIRSKFILDHQSGEIKSKGPIDFEARRTYTMNIEAKDGGGMATECKVV
                     IEILDENDNAPEVVFTSVSNSITEDAEPGTVVALFKTYDKDAEENGRVSCFVKETVPF
                     RIESSASNYYKLVTDGILDREQTPEYNVTIVATDKGKPSLSSSTSVTLHVGDVNDNAP
                     VFHQASYLIQVAENNPPGASIAQVSASDPDLGSNGLISYSIIASDLEPKSLWSYVSVN
                     RDSGVVFAQRAFDHEQLRSFQLTLQARDQGSPALSANVSMRVLVGDRNDNAPRVLYPA
                     LEPDGSALFDMVPRAAEPGYLVTKVVAVDADSGHNAWLSYHVLQASDPGLFSLGLRTG
                     EVRTARALGDRDSARQRLLVAVRDGGQPPLSATATLHLIFADSLQEVLPELRDEPLPS
                     DPQNELQFYLVVALALVSVLFLFVVILAIALRLRQSQGPAVSGCFQSGLCCKTRPGVS
                     LNYSEGTLPYSYNLYVASNCQKMSQFLTLTPEMAPPRDLCMEASVPVSVTEENNKIVS
                     DSIASNHQAPPNTDWRFSQAQRPGTSGSQNGDETGTWPNNQFDTEMLQAMILASASEA
                     ADGSSTLGGGTGTMGLSARYGPQFTLQHVPDYRQNVYIPGSNATLTNAAGKRDGKAPA
                     GGNGNKKKSGKKEKK"
     exon            2588..2646
                     /gene="Pcdhgb8"
                     /gene_synonym="Pcdhgb5"
                     /inference="alignment:Splign:2.1.0"
     exon            2647..2735
                     /gene="Pcdhgb8"
                     /gene_synonym="Pcdhgb5"
                     /inference="alignment:Splign:2.1.0"
     exon            2736..4714
                     /gene="Pcdhgb8"
                     /gene_synonym="Pcdhgb5"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ggttgaaatt gtatacattc actggaggct taaagagtga ggggggcttg aatttcctgc
       61 gtggaaaatc agattagaga ctgcgatatc ctcaaacttg gcgcatttgg gttttcttcc
      121 tggtggaagt aattcgtgaa gcctcttccc ttcacaccgg tgcaggagaa agatggagcg
      181 cagcgtgaag ctagggagca ggaccctgtg gaggcaagta ctctttccct tcttgctgcc
      241 tttgttctgc acggggcttg cagagcaagt ccgctactct attccggaag aaatggccat
      301 gggttcggtc gtgggaaacc tcgctgagga cctggggctg cctgttcagg acttactgat
      361 tcgcaatctt agagttatct cggagaaacc gtatcttact gtgaaccccg agaacgggaa
      421 catagttgtg agcgacaaaa tagatcgaga gttactctgc ttccaaagcc ctctgtgtgt
      481 cctgccctta gagattgtgg cagaaaatcc cctaaacgtt tttcacgtca gtgtagtgat
      541 agaagatata aatgataacc ctccccgttt cctccaaaat aggattgttt tgcaaatcaa
      601 tgaatttgca attccaggca ctaggtttgg cctggagtct gccatagacg cagatgtagg
      661 accgaactct ctccagagtt accagctcag tttgaatgag cacttctctc tggtggtgaa
      721 ggacaagact gaaggaaagg atgccccaga attagtgttg gagaaacctc tggacaggga
      781 aaagcagagc tcccagctct tggtcctaac agcagtggat gggggagaac cagtcctaac
      841 tggtactgct cagattcaaa tcgaagtcac tgatgccaat gataaccccc cagtgttcag
      901 ccaaagtaca tacaaagtca gtcttcgaga gaacatgccc tcaggcacct ctgtgctaac
      961 agtgatggct actgacccgg atgagggtgt caatgcagaa atcacctact ccttcaaatc
     1021 actaggagaa gatattagaa gtaagtttat cctagatcat caaagtggag aaattaaatc
     1081 caaaggccct atagactttg aggccaggag gacttacacc atgaacatag aggccaagga
     1141 tggtggcggc atggccacag aatgtaaagt tgtaatagaa attctcgatg agaacgacaa
     1201 tgccccagaa gtggttttta cctctgtgtc caattctata accgaagatg cagaaccggg
     1261 gacagtggtg gctctgttca aaacatacga taaagatgca gaagaaaatg gaagagtgag
     1321 ttgcttcgta aaagaaacag ttccttttag aattgagtcg tctgccagca attactataa
     1381 gcttgtaaca gatgggatcc tggaccggga gcagactcca gagtacaatg tcaccatcgt
     1441 cgccactgat aaaggcaagc cctctctctc ttccagcaca agtgttaccc tgcatgttgg
     1501 ggatgtcaat gacaatgctc cagttttcca ccaggcctcc tatttgatcc aagtagctga
     1561 aaataaccct ccgggagctt ccattgctca ggtcagcgcc tccgacccgg atttgggatc
     1621 caatggtctc atctcctact ccatcatagc cagcgacctt gaacctaaat cactgtggtc
     1681 ctatgtgtct gtgaaccggg acagtggggt ggtgttcgcg cagcgcgcct tcgaccacga
     1741 gcagctgcgc tccttccagc tgacactgca ggcgcgcgac cagggatcgc ccgcgctcag
     1801 cgccaacgtg agcatgcgcg tgctggtggg cgaccgcaat gacaacgcgc cacgcgtgct
     1861 gtatcccgct ctcgagccgg acggctctgc gctcttcgac atggtgcctc gcgctgccga
     1921 gcccggatac ttggtcacga aggtggtggc tgtggacgca gactcaggac acaatgcctg
     1981 gctgtcttac cacgtgctac aggccagcga tcccgggctc ttcagcttgg ggctgcgcac
     2041 aggcgaggtc cgcacagccc gtgccctggg agacagggac tcagcgcgac agcgcctact
     2101 ggtcgctgtg cgtgatggtg gacagccgcc cctctcggct acagccacgc tgcacctgat
     2161 cttcgctgac agcctgcagg aggtcctccc agaactcaga gatgagcctt tgccgtctga
     2221 cccccagaat gagcttcagt tttacctggt ggtggccttg gccttagtct cagtgctctt
     2281 tcttttcgtt gtgattctgg caatcgccct tcgccttcgg cagtcccagg gtcctgctgt
     2341 ctcgggctgt tttcagtcag gcctttgctg taagacgaga ccaggggttt ctctcaacta
     2401 cagcgagggg actcttcctt attcctacaa tctctacgtt gcctccaatt gtcaaaaaat
     2461 gtctcaattt cttaccttga cgccagaaat ggcccctccg cgagatcttt gtatggaagc
     2521 ttccgtgcca gtgagtgtca ctgaggagaa taacaagata gtctctgatt ctattgcttc
     2581 taaccaccaa gccccgccca acactgactg gcgtttctct caagcccaga gacccggcac
     2641 gagcggatcc caaaatgggg atgaaaccgg cacctggccc aacaaccagt tcgatacaga
     2701 gatgctgcaa gccatgatct tggcctctgc cagtgaagcc gctgatggga gctccactct
     2761 gggagggggc actggcacta tgggtttgag cgctcgatat ggaccccagt ttaccctgca
     2821 gcacgtgcct gactaccgcc agaacgtgta catccctggc agcaatgcca cactgaccaa
     2881 cgcagctggc aaacgagatg gcaaggctcc ggcaggcggc aatggcaaca agaagaagtc
     2941 gggcaagaaa gagaagaagt aatatggagg ccaggccttg agccacaggg cagcctccct
     3001 ccccagccag tccagcttgt ccttacttgt acccaggcct cagaatttca gggctcaccc
     3061 caggattctg gtaggagcca cagccaggcc atgctccccg ttgggaaaca gaaacaagtg
     3121 cccaagccaa caccccctct ttgtacccta ggggggttga atatgcaaag agagttctgc
     3181 tgggaccccc tatccaatca gtgattgtac ccacataggt agcagggtta gtgtggatac
     3241 acacacacac acacacacac acacacacac acacacaaac accatgccac actcccctag
     3301 ttacagctga actccccatc ttccaaccca gtcaggctca ttcatctcca gcctccctct
     3361 ccccacccca ccctttcagt caacaccctc tctttgagcc aggtagttgg gctgttgggg
     3421 tgacaggtga gctaaggggg ctcctagttc tgaacaggtg ggagagtatt acaatccttt
     3481 ggcctctcct tcagttcagc tgtcccccaa agcatggttt ggtaccagtc ttctcatttc
     3541 ctcctagagc ctgagaccaa tgcttaagtt ttggggaaca gtcaccatgc ccctggtact
     3601 gatgatgctt gctggatttt tgggaaggca ttttgctact aagcctcttt tcaatgcctg
     3661 gggactacca gtcttctgtt ctccattgtt tgatgttccc actgcatgct gtgacttcct
     3721 actcctcaaa gaagagactc ctttgcatgt ctggagacag tagggggtgg taaactaaag
     3781 ggaagctgag tgtatactgc tgggagtggg ggcagtggac aaaacagcct gttaataggg
     3841 tcttgcaagg ggctctgtac gtacccaggg tactggctca atcctcaaat tctagccata
     3901 gacaaacatc aggccagacc cctccctcct ggttcagcct gggcagcttg ggctgagcca
     3961 ccaggaccaa tggatttaag ctgacatttc agtccaagaa gacttctaag tgagtttaag
     4021 accagagagg aaagaggggc ctctgtgggt gctgggtact ccagaggtgc ccttggtggg
     4081 agggtcagtg gtcctagcag gaagggagcc cagcaaggtc attcttggac cctgggtcta
     4141 gtccggtagc tagaacaagg gaccaagtgg ctataaagtc tcagccaatg atgaggcttt
     4201 tcccctgggc ctctgggccc ctgtattcct caagcccctg gcctccacct taccaggtgc
     4261 catttctcag aaggccactg cccaggcccc caggccgccc cctcgtggcc acagaccggt
     4321 taaagccccc cagtgcctcc ttgtgcatag aacttcctct gcccgagccc ttacagtagt
     4381 gtagaagccc ccttcctcct cccgctggtg tagaatagcc aatagtatag tgtggtgtgc
     4441 ttttacgtga tggcgagtgg gcagcgggcg gtgggctgtg cgcagccgtc tgtcctttga
     4501 atctcaatct gcctgcgcgg ccagtgctgt gttttgtgct gtgtccacac gctgcggcga
     4561 cccctccctg tactgacttc tctataaaag cttctcttcg catagtcacg tagctcctgc
     4621 ccatccccct tccgatatct ctcgcaagtt ttatactcta atatttatat ggcttttttc
     4681 ttcgaaaatt aaaaataaaa aatggtttct tctg
//
