LOCUS       NM_001037154            4712 bp    mRNA    linear   ROD 21-MAR-2023
DEFINITION  Rattus norvegicus protocadherin gamma subfamily A, 3 (Pcdhga3),
            mRNA.
ACCESSION   NM_001037154
VERSION     NM_001037154.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 4712)
  AUTHORS   O'Leary R, Reilly JE, Hanson HH, Kang S, Lou N and Phillips GR.
  TITLE     A variable cytoplasmic domain segment is necessary for
            gamma-protocadherin trafficking and tubulation in the
            endosome/lysosome pathway
  JOURNAL   Mol Biol Cell 22 (22), 4362-4372 (2011)
   PUBMED   21917590
REFERENCE   2  (bases 1 to 4712)
  AUTHORS   Zou C, Huang W, Ying G and Wu Q.
  TITLE     Sequence analysis and expression mapping of the rat clustered
            protocadherin gene repertoires
  JOURNAL   Neuroscience 144 (2), 579-603 (2007)
   PUBMED   17110050
REFERENCE   3  (bases 1 to 4712)
  AUTHORS   Wu Q.
  TITLE     Comparative genomics and diversifying selection of the clustered
            vertebrate protocadherin genes
  JOURNAL   Genetics 169 (4), 2179-2188 (2005)
   PUBMED   15744052
REFERENCE   4  (bases 1 to 4712)
  AUTHORS   Murata Y, Hamada S, Morishita H, Mutoh T and Yagi T.
  TITLE     Interaction with protocadherin-gamma regulates the cell surface
            expression of protocadherin-alpha
  JOURNAL   J Biol Chem 279 (47), 49508-49516 (2004)
   PUBMED   15347688
REFERENCE   5  (bases 1 to 4712)
  AUTHORS   Zhang T, Haws P and Wu Q.
  TITLE     Multiple variable first exons: a mechanism for cell- and
            tissue-specific gene regulation
  JOURNAL   Genome Res 14 (1), 79-89 (2004)
   PUBMED   14672974
REFERENCE   6  (bases 1 to 4712)
  AUTHORS   Johnson KJ, Patel SR and Boekelheide K.
  TITLE     Multiple cadherin superfamily members with unique expression
            profiles are produced in rat testis
  JOURNAL   Endocrinology 141 (2), 675-683 (2000)
   PUBMED   10650949
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AY574014.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AY574014.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132268, SAMD00132291
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..4712
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="18"
                     /map="18p11"
     gene            1..4712
                     /gene="Pcdhga3"
                     /note="protocadherin gamma subfamily A, 3"
                     /db_xref="GeneID:498847"
                     /db_xref="RGD:1598664"
     exon            1..2585
                     /gene="Pcdhga3"
                     /inference="alignment:Splign:2.1.0"
     CDS             171..2960
                     /gene="Pcdhga3"
                     /note="protocadherin gamma-A3"
                     /codon_start=1
                     /product="protocadherin gamma-A3 precursor"
                     /protein_id="NP_001032231.1"
                     /db_xref="GeneID:498847"
                     /db_xref="RGD:1598664"
                     /translation="MIRLGRGTAGALLCALLGTLSAAGFRQIRYSVPEELDKGSYVGN
                     ISKDLGLEPHELAERGVRIISRGRSQLFSLDPRSGSLVTAGRIDREELCAQSAPCVVS
                     FNILVEDKLKIFEVEVDISDINDNAPSFPTEELEIKIGELTVPGTRFPLKTAFDPDVG
                     MNSLQNYKLNSNDYFSLAVNSVIDDAKYPELVLERALDREKKAVHQLDLIASDGGDPA
                     HTGKLCIQVIVLDANDNPPVFTKPEYRVSVLENVPVGTRLTTVNATDPDEGFNAQVSY
                     ILDKMPGKIAQIFHLNSVTGDVSILKSLDYEDAVFYEIKIEAQDGPGLFSRAKILVTV
                     LDVNDNAPEISVTSLTSSVPEEAPAGREIALINVHDRDSGQNGQVSVFVLGNLPFTLE
                     KSIDQYYRLVTARSLDHEKESQYNISLRATDGGSPPLSTETHITLHVTDINDNPPTFT
                     RASYLAYIPENNARGASIFSVTAQDPDTDKNAQITYSLAEDTLQGVPLSSFVSINSNT
                     GVLYALCSFDYEQFRDLQLHITARDSGNPPLSSNSTLSLFVLDKNDNSPEILYPALPV
                     DGSTGVELAPRSAEPGYLVTKVVAVDKDSGQNSWLSYRLIKASEPGLFSVGLHTGEVR
                     TARALLDRDALKQSLVVAVQDHGQPPLSATVTLTIAVADSIPDILGDLESIHTPANPK
                     NSDLTLYLVVAVAAVSCIFLAFVIVLLALRLRRWHSSRLLQASGNGLAGIPASHFVGV
                     DGVQAFLQTYSQEVSLTAGSRKSHLIFPQPNYADTLISQESCGKSEPLIIPQDLLETQ
                     EDPELPEQAPPNTDWRFSQAQRPGTSGSQNGDETGTWPNNQFDTEMLQAMILASASEA
                     ADGSSTLGGGTGTMGLSARYGPQFTLQHVPDYRQNVYIPGSNATLTNAAGKRDGKAPA
                     GGNGNKKKSGKKEKK"
     exon            2586..2644
                     /gene="Pcdhga3"
                     /inference="alignment:Splign:2.1.0"
     exon            2645..2733
                     /gene="Pcdhga3"
                     /inference="alignment:Splign:2.1.0"
     exon            2734..4712
                     /gene="Pcdhga3"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ctctgctgca aagcaacacc aagaacaatc tgagaagaca gaagcgacct caccacatca
       61 tcgggcaact ctgtggtgtg tgaattaaat ccatgaaaga tttaactact tgaaggggta
      121 aggctgggac ccatcgtggg aatcagagga aaaataaaac agaaaaggaa atgatccgac
      181 tgggacgagg aaccgccgga gctttgttgt gcgcgctcct ggggacactg agcgcggctg
      241 gcttcaggca gatccgctac tccgtgccgg aggagctgga caaaggctcc tacgtgggca
      301 acatctccaa ggacctgggg ctggagcccc acgagctggc ggagcgcggg gtccgcatca
      361 tctccagagg taggtcgcag cttttctctc tggacccgcg aagcggcagc ttggttaccg
      421 cgggcaggat agaccgggag gagctgtgcg cccagagcgc gccctgtgtc gtgagcttta
      481 acatccttgt agaggataag ctgaaaatat ttgaggtaga agttgacatc agcgatatta
      541 atgataatgc tcctagtttt ccaacggagg aattggaaat aaaaattggg gaactaacag
      601 ttcctggaac ccgatttcca cttaaaactg cgtttgaccc ggatgtgggc atgaactccc
      661 tgcagaacta taagctcaac tccaatgact acttctcctt ggctgtgaac agcgtcatcg
      721 atgacgccaa gtacccagag ctggtgctgg agcgagccct ggatcgtgag aaaaaggcag
      781 tccatcagct tgatctcatt gcctctgatg gcggagaccc tgcccacacc ggcaagttgt
      841 gcatccaagt gatagtcttg gatgcaaatg acaacccgcc cgtgtttact aagccagagt
      901 accgtgtcag tgttctggaa aatgtgccag tgggcacgcg gctgaccaca gtgaatgcca
      961 ctgatcctga cgagggattc aatgctcaag tgtcctacat tctagataaa atgcctggga
     1021 aaattgctca gattttccat ctcaattcag tgactggaga tgtatcaata ttaaaaagtc
     1081 ttgattatga ggacgctgta ttctatgaaa tcaaaattga agcacaagac ggaccaggtc
     1141 ttttttcaag agccaagatt cttgtcacgg ttctggatgt gaatgacaac gccccagaaa
     1201 tctcagtcac ttccctcaca agctcggtcc cagaggaggc tcctgctgga agagaaatcg
     1261 ctcttatcaa tgtacatgac cgagattctg gccagaacgg gcaagtctca gtttttgtcc
     1321 tgggaaatct gccctttact ctagaaaaat caatcgacca atactaccgc ttagtgacag
     1381 ccagatctct ggatcatgag aaggagtctc aatataatat cagtctgaga gccactgatg
     1441 ggggaagccc accactatcc acagaaactc atatcactct gcatgtgaca gacatcaatg
     1501 acaaccctcc taccttcaca cgtgcctcct atttagccta tatcccagaa aacaatgcta
     1561 ggggagcatc catcttctct gttacagcac aggacccgga cactgacaag aatgcacaaa
     1621 tcacttactc actggctgag gacacacttc agggggtgcc actgtcatcc ttcgtctcca
     1681 tcaactctaa tactggtgtc ctgtatgccc tttgctcctt tgactacgag cagtttagag
     1741 acctgcagtt acacataaca gccagggaca gtgggaaccc tccactcagc agcaactcga
     1801 ccctgagtct atttgtgctg gacaagaatg acaactcacc tgaaatcctg taccctgccc
     1861 tcccagtaga tggctccact ggggttgagt tagcaccccg ctctgcagaa cctggatacc
     1921 tggtaaccaa ggtggtggca gttgacaaag attcaggaca aaactcttgg ctgtcctacc
     1981 gcctgatcaa ggccagcgag ccagggctct tctcggtggg gctgcacaca ggcgaggtac
     2041 gcacggctcg ggccctcctg gaccgagatg ctctcaaaca gagcctggtg gtggctgtgc
     2101 aggaccatgg ccagccccct ctttccgcca cagtcacact caccatagca gtggctgaca
     2161 gcattcctga catcctgggg gacttggaaa gcatccatac ccctgctaac cccaaaaatt
     2221 cagacctcac cctctacctg gtggtggcag tggctgcggt ctcctgcatc ttcctggcct
     2281 ttgtcattgt gctgctggcc cttaggctac ggcgttggca ctcatcgcgc ctgctacagg
     2341 cttcaggaaa tgggttagcc ggcataccag cctctcactt tgtgggtgta gatggggtgc
     2401 aagcgttcct gcagacctat tcccaggaag tttcgcttac tgcaggctct aggaagagtc
     2461 acctgatctt cccgcagccc aactatgcag acacgctcat cagccaggag agctgtggga
     2521 aaagcgagcc tcttataata cctcaagatt tacttgaaac gcaagaagac cccgagctgc
     2581 ctgagcaagc cccgcccaac actgactggc gtttctctca agcccagaga cccggcacga
     2641 gcggatccca aaatggggat gaaaccggca cctggcccaa caaccagttc gatacagaga
     2701 tgctgcaagc catgatcttg gcctctgcca gtgaagccgc tgatgggagc tccactctgg
     2761 gagggggcac tggcactatg ggtttgagcg ctcgatatgg accccagttt accctgcagc
     2821 acgtgcctga ctaccgccag aacgtgtaca tccctggcag caatgccaca ctgaccaacg
     2881 cagctggcaa acgagatggc aaggctccgg caggcggcaa tggcaacaag aagaagtcgg
     2941 gcaagaaaga gaagaagtaa tatggaggcc aggccttgag ccacagggca gcctccctcc
     3001 ccagccagtc cagcttgtcc ttacttgtac ccaggcctca gaatttcagg gctcacccca
     3061 ggattctggt aggagccaca gccaggccat gctccccgtt gggaaacaga aacaagtgcc
     3121 caagccaaca ccccctcttt gtaccctagg ggggttgaat atgcaaagag agttctgctg
     3181 ggacccccta tccaatcagt gattgtaccc acataggtag cagggttagt gtggatacac
     3241 acacacacac acacacacac acacacacac acacaaacac catgccacac tcccctagtt
     3301 acagctgaac tccccatctt ccaacccagt caggctcatt catctccagc ctccctctcc
     3361 ccaccccacc ctttcagtca acaccctctc tttgagccag gtagttgggc tgttggggtg
     3421 acaggtgagc taagggggct cctagttctg aacaggtggg agagtattac aatcctttgg
     3481 cctctccttc agttcagctg tcccccaaag catggtttgg taccagtctt ctcatttcct
     3541 cctagagcct gagaccaatg cttaagtttt ggggaacagt caccatgccc ctggtactga
     3601 tgatgcttgc tggatttttg ggaaggcatt ttgctactaa gcctcttttc aatgcctggg
     3661 gactaccagt cttctgttct ccattgtttg atgttcccac tgcatgctgt gacttcctac
     3721 tcctcaaaga agagactcct ttgcatgtct ggagacagta gggggtggta aactaaaggg
     3781 aagctgagtg tatactgctg ggagtggggg cagtggacaa aacagcctgt taatagggtc
     3841 ttgcaagggg ctctgtacgt acccagggta ctggctcaat cctcaaattc tagccataga
     3901 caaacatcag gccagacccc tccctcctgg ttcagcctgg gcagcttggg ctgagccacc
     3961 aggaccaatg gatttaagct gacatttcag tccaagaaga cttctaagtg agtttaagac
     4021 cagagaggaa agaggggcct ctgtgggtgc tgggtactcc agaggtgccc ttggtgggag
     4081 ggtcagtggt cctagcagga agggagccca gcaaggtcat tcttggaccc tgggtctagt
     4141 ccggtagcta gaacaaggga ccaagtggct ataaagtctc agccaatgat gaggcttttc
     4201 ccctgggcct ctgggcccct gtattcctca agcccctggc ctccacctta ccaggtgcca
     4261 tttctcagaa ggccactgcc caggccccca ggccgccccc tcgtggccac agaccggtta
     4321 aagcccccca gtgcctcctt gtgcatagaa cttcctctgc ccgagccctt acagtagtgt
     4381 agaagccccc ttcctcctcc cgctggtgta gaatagccaa tagtatagtg tggtgtgctt
     4441 ttacgtgatg gcgagtgggc agcgggcggt gggctgtgcg cagccgtctg tcctttgaat
     4501 ctcaatctgc ctgcgcggcc agtgctgtgt tttgtgctgt gtccacacgc tgcggcgacc
     4561 cctccctgta ctgacttctc tataaaagct tctcttcgca tagtcacgta gctcctgccc
     4621 atcccccttc cgatatctct cgcaagtttt atactctaat atttatatgg cttttttctt
     4681 cgaaaattaa aaataaaaaa tggtttcttc tg
//
