LOCUS       NM_001416815            6105 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus protocadherin beta 22 (Pcdhb22), mRNA.
ACCESSION   NM_001416815 NM_001014808 XM_226034
VERSION     NM_001416815.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 6105)
  AUTHORS   Junghans,D., Heidenreich,M., Hack,I., Taylor,V., Frotscher,M. and
            Kemler,R.
  TITLE     Postsynaptic and differential localization to neuronal subtypes of
            protocadherin beta16 in the mammalian central nervous system
  JOURNAL   Eur J Neurosci 27 (3), 559-571 (2008)
   PUBMED   18279309
REFERENCE   2  (bases 1 to 6105)
  AUTHORS   Wu,Q.
  TITLE     Comparative genomics and diversifying selection of the clustered
            vertebrate protocadherin genes
  JOURNAL   Genetics 169 (4), 2179-2188 (2005)
   PUBMED   15744052
REFERENCE   3  (bases 1 to 6105)
  AUTHORS   Zhang,T., Haws,P. and Wu,Q.
  TITLE     Multiple variable first exons: a mechanism for cell- and
            tissue-specific gene regulation
  JOURNAL   Genome Res 14 (1), 79-89 (2004)
   PUBMED   14672974
REFERENCE   4  (bases 1 to 6105)
  AUTHORS   Johnson,K.J., Patel,S.R. and Boekelheide,K.
  TITLE     Multiple cadherin superfamily members with unique expression
            profiles are produced in rat testis
  JOURNAL   Endocrinology 141 (2), 675-683 (2000)
   PUBMED   10650949
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000018.1.
            
            On Feb 17, 2023 this sequence version replaced NM_001014808.1.
            
            ##Evidence-Data-START##
            Transcript is intronless :: SRR26643290.51244.1,
                                        SRR26360172.1985824.1 [ECO:0000345]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-6105              JAXUCZ010000018.1  29497038-29503142
FEATURES             Location/Qualifiers
     source          1..6105
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="18"
                     /map="18p11"
     gene            1..6105
                     /gene="Pcdhb22"
                     /gene_synonym="pcdh-T5"
                     /note="protocadherin beta 22"
                     /db_xref="GeneID:307486"
                     /db_xref="RGD:1310328"
     exon            1..6105
                     /gene="Pcdhb22"
                     /gene_synonym="pcdh-T5"
                     /inference="alignment:Splign:2.1.0"
     CDS             122..2509
                     /gene="Pcdhb22"
                     /gene_synonym="pcdh-T5"
                     /note="protocadherin-T5"
                     /codon_start=1
                     /product="protocadherin beta-15"
                     /protein_id="NP_001403744.1"
                     /db_xref="GeneID:307486"
                     /db_xref="RGD:1310328"
                     /translation="MKIGREHRQRQVLLIFLFLGVAGAGWKPRRYFVMEETPSGTVLA
                     DLVQDLGLGVAELAARGAQVVCEENESRLQLDLQTGKLILNEKLDREELCGPTEPCVI
                     HFQVLLKKPLEIFQAELQVGDINDHSPEFPEREMTVKIIETSPVDTAFLLKTAQDLDV
                     GNNSIQNYKIGTNSHFHVSIRNRGDGRKYPELVLDKELDREEQAEFRLTLTALDGGSP
                     PRTGTSQIRIIVLDVNDNAPEFAQAFYRVQILENSPLGSLVAKVSAKDSDIGTNGEVS
                     YSLFHSSQKMSKTFELNALSGEVRLIKTLDFETTSSYEVDIEASDGGGLSGKCSVSIQ
                     VVDVNDNYPELIMSSLTNPIPENSPETEVALFRVRDRDSGENGKTICSIQEGVPFTLE
                     PSVENFFRLMTDGALDRESRAEYNITIFVSDLGTPRLTTQHTITVQVSDINDNAPAFT
                     QTSYTMFVHENNSPALHIGTISATDSDSGSNAHITYSLLPPHDPQLALTSLISINTDN
                     GQLFALRAMDYEALQAFEFHVGATDRGSPALSSQALVRVVVLDNNDNAPFVLYPLQNA
                     SVPFTELLPRAAEPGYLITKVVAVDSDSGQNAWLSFQLLKATEPGLFSVWAHNGEVRT
                     TRLLNERDVHKHKLLLMVKDNGEPPRSASVMLQVLLVDGFSQPYLPLPEVVRDPSDQD
                     EDVLTLYLVIALASVSSLFLLSVLLFVGVRLCRRAREATPGVCSMAEGHFPGHLVDVS
                     GVGTLSQSYQYEVCLTGDSQSNEFKFLKPVFSSIVDQNSGRELGDNSSSPSILGM"
ORIGIN      
        1 aggcagagct cagaccttta acgctccaga gaatgctgcc aatctacact tccaagaaag
       61 ctattaacta acaggtttac cgctatctgg atgtccttgt accctgggtg cagaaacaaa
      121 gatgaagatt ggaagagaac acaggcaaag gcaagttctg ttaatctttc ttttcctggg
      181 agtggctggg gcgggctgga aaccccgccg ttactttgtg atggaggaaa cacccagcgg
      241 cactgttttg gcagatctag tccaggacct agggctggga gttgcggagc tagctgctcg
      301 aggagcccaa gtagtgtgtg aggaaaatga atcacgcttg cagcttgatc tacagactgg
      361 gaagctaatc ttaaatgaaa aactggaccg ggaggagctg tgcggcccca ctgagccctg
      421 tgtcattcat ttccaagtgt tactgaaaaa accactggaa atatttcaag ctgagctaca
      481 agtaggagac atcaatgatc attctcccga gtttcctgaa agagaaatga ccgtgaaaat
      541 catagagact agccctgttg acactgcatt tctactcaaa accgctcagg atttggatgt
      601 gggaaataac agcattcaga actataaaat tggtaccaat tctcatttcc atgtttccat
      661 ccgcaaccga ggtgatggga gaaaataccc agagctcgtg ctggacaaag agcttgatcg
      721 cgaggagcag gcagagttca gattaactct gaccgcgctg gatggcggtt ctccacccag
      781 gactggcacc tcgcaaatcc ggattattgt cttggatgtc aatgacaatg cccctgagtt
      841 tgcacaggct ttctaccgtg tgcaaatcct agagaacagc cccttgggtt ccctggttgc
      901 taaggtctct gctaaggatt cagacattgg gacaaatgga gaggtatcat actctctttt
      961 tcatagctct cagaagatga gcaaaacttt tgagctaaat gctctatcag gagaagttcg
     1021 actaattaaa acactggact ttgagacaac atcttcatat gaagtagaca tagaggcatc
     1081 cgatggcggg ggtctttctg gaaaatgttc tgtttctatt caggtggtgg atgtcaatga
     1141 taattaccca gaactaatta tgtcatccct caccaacccc atcccagaaa attcaccaga
     1201 gacagaggtg gcactgtttc gggttcgaga ccgagactct ggagaaaatg gaaagacaat
     1261 ttgttccatc caggaaggtg ttccctttac attggaacct tctgttgaga acttctttag
     1321 actgatgaca gacggagctt tggacagaga gagcagagct gagtataaca tcaccatctt
     1381 cgtctcagac ctgggcacac ccaggctcac aacccagcac accataacag tgcaggtgtc
     1441 tgacatcaac gacaacgccc ccgccttcac ccaaacctcc tacaccatgt ttgtccacga
     1501 gaacaacagc cccgccctgc acataggcac catcagcgcc acagactcag actcaggatc
     1561 caatgcccac atcacctact cgctgctgcc gccccatgac ccgcagctgg ccctcacctc
     1621 acttatctcc attaacactg acaatggcca gctattcgcg ctcagggcaa tggactatga
     1681 ggccctgcag gccttcgagt tccacgtggg tgccacggac cgaggctcac ctgcactcag
     1741 cagccaggct ctggtgcggg tggtggtgct ggacaacaat gacaatgcgc ccttcgtgct
     1801 ctacccactg cagaacgcct ctgtgccctt tactgagcta ctgcccaggg cggcagagcc
     1861 tggctacctg atcaccaagg tggtagcagt ggactctgac tctggccaga atgcctggct
     1921 gtcgttccag ctgcttaagg ccacggagcc cggactgttc agcgtgtggg cgcataatgg
     1981 cgaagtgcgc accaccaggc tgctgaacga gcgcgatgtg cacaagcaca aactgctgct
     2041 aatggtcaag gacaatggag agcctccgcg ctctgccagc gtcatgcttc aagtgcttct
     2101 ggtggatggc ttctcccagc cctacctacc tctgccagag gtggtgcgcg accccagtga
     2161 ccaagatgag gacgtgctca ctctgtacct ggttattgcc ttggcttctg tgtcttctct
     2221 cttccttttg tctgtgctgc tgtttgtcgg ggtgaggctg tgcaggaggg ccagggaggc
     2281 cactccgggt gtctgctcta tggctgaggg acactttcct ggtcacctag tggatgtcag
     2341 tggtgtgggg accctgtccc agagctacca gtatgaggtg tgtcttacag gagattctca
     2401 gagtaatgag ttcaaattct tgaagcctgt gttttctagt attgtagacc aaaactctgg
     2461 tagggaacta ggagataatt catcctcccc aagcatttta ggcatgtgaa acaacacatt
     2521 tcattctttg tatacttctg ttgcttttgc attctcgttt tcttttcgaa tctggtagta
     2581 atgttcactt cttttgtttt tcattttctc tactagttta tatagtattt ttgtttgttt
     2641 attggcttta ttacgtattt ttccaaattt gttgttactg aacattttac atcaggacac
     2701 ttcatgttcc tgattgaatt tgcagtagtc tctcctaaag aatgtgtatt ttctgtaatg
     2761 aataaaattc taattataaa agtatatgtc ctggcctatg gggaatggat tggtttatag
     2821 agagcttgtg tactttgttg gagaccttag gttaggtctc tctgtaaatc cagccccaga
     2881 ggtggagaca cactatcggg aatttaaggt catcatcttc tacatagaga atgcaagctc
     2941 agcctgggct atgtgatgat caagggagat taggtctcaa aattaaaaat atattcctgg
     3001 tgtgcgtgat gccatagaag gacatatgat ttcttttaaa taatacttca ttttaaaact
     3061 ggaagtcctt agttttattg tttgcctggg catgacttcg gtagcctcat tttgttctct
     3121 ctggaagcag ttcatagtca ttaatgccgt ttcttccaga ttcccttatt atattttcta
     3181 ctctccaaca ctgtacatat cgtctcatga aaccggaccc gcatcatcca ttctttgtct
     3241 ccaaagttaa cactgaaaag gctaaaagtc tcttcattct ctttagctga ttgtcacact
     3301 tggcatgtta ctgatatcat aaactcaata agctccagga agagtgatgc atgtgtgtgt
     3361 gcgtgtgtgt gtgtgtgtgt gtgtgtgtgt gtgcacgcgc tactatcact tattatagtg
     3421 aggaaatcct gatgtaaatc ccaaaattcc tggtaatttc tggtggtaca gcatgccaat
     3481 atttacatgc tttggatgat gatattgctc taattgacaa ggaatttgga agaaaatgta
     3541 ttatatagaa tttgcatttg ttaactaaac aaatttagta aagatttgtt gatgtagtat
     3601 taaatgattt ggagaaattt tcagggggaa aactgattcc ccaaatatgt tcagtcctga
     3661 tccctagaat ctgtgaatat tactttatat tgtagagata aaacatgaac aaaattaagg
     3721 ttgttcataa gctaaactta aaacaggatg tacagtctag atcatttaag tgggtctgag
     3781 agaaccagtg aaaggcttta aaagcaaagt tgaatctacc tagagatgaa gaatagccag
     3841 ccatagtggc acatgtcttt agtccttggg aggcagagac aagcagatct ctgtgagttc
     3901 aaggccagct ggtctacatg gtgagttcca ggacagctag gaccctgtct tgaaaaacca
     3961 tgtgagagag gtgtgggaag agaaagaaat tccctaagga ctttaggtgc atcttgtgat
     4021 tcagtgtttt aacctgccac attctgaata tcatgtggat tttgaacttt ctagtgaact
     4081 cccagagtag aataagtcac ttccttgtgg tatgttttct gatcgttctc cttctccagg
     4141 tgaagcctga ggatgcagct gataaaaaga cttaaaaata tggaagtgga gccaggcagt
     4201 ggcggtgtcc tcctttaatc ccagcactca caaggcagag gcaggcagat ctttaagttt
     4261 gaggccagtc tggtctacag agtaagttcc agtacagcca gggctacaga gataaactct
     4321 gttttggaga aaggtatgga cctgggtttt taactgggtg gtggtcaggc acagaagaaa
     4381 ttgcagacac agaaaatgtt caggttgctt tggtagactt ggtagaaata tggtattaac
     4441 aagtctgcca gtaaagacac gagaggaagt gaggcatgta gtatttataa aatacattgg
     4501 cttatagaac ttataattta aagcaacaat ggcaagaaat ctggatgtta gagttacttc
     4561 tagttggagc ccaggcaagg aaaacattat taaaaactgg aggaaattaa cacttttatt
     4621 tttatgcaat tgcagaaaac ttagctgaat catgacttac attatatgag ggaaagaaca
     4681 cattcacttg gtcctttggc agtggaaatt tccaggaaaa ctgccagaac ttgatttctt
     4741 ttcactggtt atagtaaagt atcagatgaa aaataaaaac aaaatatatc caggacctga
     4801 tgactggagg gaaactctca ttctaattac attataacat atgttaaaat caggaaaaat
     4861 cactggcaag gatgcatgca tgggagagaa gtcaactggg aaacatttca ctagtgcctg
     4921 ggaaatctga aagttaataa tagaaatgag agttacagag ttaataatac agaagcccca
     4981 ttgaagggcc aaacacattt aattggatat tctatttatt tacttttcaa ctgttatccc
     5041 ctttcctggt ttcccctctg gaaaccccta tctcatcccc tccctctgtt tctatgaggg
     5101 tactcctcca cccacccacc cacccactcc agcctccctg ccctggtgtt cacctacaca
     5161 ggggtattga gccttcgtag taccaaggct tctcctccca ttaatgtcaa acaatgccat
     5221 cctctactac atatgcggct ggagccatga gtcattccaa gtgtactctt tggttggtga
     5281 tttagtccct gggagttctg gggggtctgg ttgattgata ttgttgttct tcaagcacat
     5341 ttttaatgaa tttttcctca tctttagata taatgtgatg ctaattactg taatcgtata
     5401 acacactctc tgactgacag aactttcaga agttgatccc atcttcccat tttccattgt
     5461 gcctgctaat gggttagaaa atagcaagta ttattttttc caggatactg tcattagcaa
     5521 ccaatcagta ggagtagttc ttgtcctttg gaagcaatga caaaaaaact taaataatgt
     5581 tgatttgaat agaaaacgag aaaaggaaat gtattactgg tatatttaga tttggacttt
     5641 ctcttcattt gtctaaacat tatacttgga tcaattctat cagccttctc atatgttgaa
     5701 atgtttttga agcaggccca gagattcgaa cacgttaggt cagttcattc aagttcccat
     5761 tgtctcatta agttagctgg ccatcgcttc tccctcttct attttataaa ggtttgtata
     5821 aggtatttgt gattgtttga gtgaaaattg tttcctataa gctaataatt cgagtacttg
     5881 gtccccagtt gctggatctg tttaaggagg cagtacgggt ctgctggaga aagcccctca
     5941 ctgcgggtga gcttcgagag ttcacagcat cactccacaa ccaggttctt ctcttcccta
     6001 gtgtttgtgg ctcaatatgt gacctgctgc ctgctgctgt acctcacaac cattgtatat
     6061 tctccttctg gaaacgtaag caaaaataaa cactttcttc cttca
//
