LOCUS       NM_001191883            2022 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus poly(rC) binding protein 4 (Pcbp4), mRNA.
ACCESSION   NM_001191883 XM_343468
VERSION     NM_001191883.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2022)
  AUTHORS   Bogdan,A.R., Miyazawa,M., Hashimoto,K. and Tsuji,Y.
  TITLE     Regulators of Iron Homeostasis: New Players in Metabolism, Cell
            Death, and Disease
  JOURNAL   Trends Biochem Sci 41 (3), 274-286 (2016)
   PUBMED   26725301
  REMARK    Review article
REFERENCE   2  (bases 1 to 2022)
  AUTHORS   Lane,D.J., Merlot,A.M., Huang,M.L., Bae,D.H., Jansson,P.J.,
            Sahni,S., Kalinowski,D.S. and Richardson,D.R.
  TITLE     Cellular iron uptake, trafficking and metabolism: Key molecules and
            mechanisms and their roles in disease
  JOURNAL   Biochim Biophys Acta 1853 (5), 1130-1144 (2015)
   PUBMED   25661197
  REMARK    Review article
REFERENCE   3  (bases 1 to 2022)
  AUTHORS   Zheng,S., Damoiseaux,R., Chen,L. and Black,D.L.
  TITLE     A broadly applicable high-throughput screening strategy identifies
            new regulators of Dlg4 (Psd-95) alternative splicing
  JOURNAL   Genome Res 23 (6), 998-1007 (2013)
   PUBMED   23636947
REFERENCE   4  (bases 1 to 2022)
  AUTHORS   Castello,A., Fischer,B., Eichelbaum,K., Horos,R., Beckmann,B.M.,
            Strein,C., Davey,N.E., Humphreys,D.T., Preiss,T., Steinmetz,L.M.,
            Krijgsveld,J. and Hentze,M.W.
  TITLE     Insights into RNA biology from an atlas of mammalian mRNA-binding
            proteins
  JOURNAL   Cell 149 (6), 1393-1406 (2012)
   PUBMED   22658674
REFERENCE   5  (bases 1 to 2022)
  AUTHORS   Scoumanne,A., Cho,S.J., Zhang,J. and Chen,X.
  TITLE     The cyclin-dependent kinase inhibitor p21 is regulated by
            RNA-binding protein PCBP4 via mRNA stability
  JOURNAL   Nucleic Acids Res 39 (1), 213-224 (2011)
   PUBMED   20817677
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from
            JAXUCZ010000008.1.
            
            On Jul 17, 2010 this sequence version replaced XM_343468.4.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26360172.874304.1,
                                           SRR26360194.2396096.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-156               JAXUCZ010000008.1  115971751-115971906
            157-301             JAXUCZ010000008.1  115978112-115978256
            302-325             JAXUCZ010000008.1  115978390-115978413
            326-358             JAXUCZ010000008.1  115978511-115978543
            359-475             JAXUCZ010000008.1  115978761-115978877
            476-607             JAXUCZ010000008.1  115979105-115979236
            608-736             JAXUCZ010000008.1  115979386-115979514
            737-811             JAXUCZ010000008.1  115979745-115979819
            812-856             JAXUCZ010000008.1  115980000-115980044
            857-920             JAXUCZ010000008.1  115980128-115980191
            921-973             JAXUCZ010000008.1  115980300-115980352
            974-1143            JAXUCZ010000008.1  115980439-115980608
            1144-2022           JAXUCZ010000008.1  115981109-115981987
FEATURES             Location/Qualifiers
     source          1..2022
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="8"
                     /map="8q32"
     gene            1..2022
                     /gene="Pcbp4"
                     /note="poly(rC) binding protein 4"
                     /db_xref="GeneID:363133"
                     /db_xref="RGD:1307910"
     exon            1..156
                     /gene="Pcbp4"
                     /inference="alignment:Splign:2.1.0"
     exon            157..301
                     /gene="Pcbp4"
                     /inference="alignment:Splign:2.1.0"
     CDS             221..1432
                     /gene="Pcbp4"
                     /codon_start=1
                     /product="poly(rC)-binding protein 4"
                     /protein_id="NP_001178812.1"
                     /db_xref="GeneID:363133"
                     /db_xref="RGD:1307910"
                     /translation="MSSSDAGLEEEPELSITLTLRMLMHGKEVGSIIGKKGETVKRIR
                     EQSSARITISEGSCPERITTITGSTAAVFHAVSMIAFKLDEDLCAAPANGGSVSRPPV
                     TLRLVIPASQCGSLIGKAGTKIKEIRETTGAQVQVAGDLLPNSTERAVTVSGVPDAII
                     LCVRQICAVILESPPKGATIPYHPSLSLGTVLLSANQGFSVQGQYGAVTPAEVTKLQQ
                     LSGHAVPFASPSVVPGLDPSTQTSSQEFLVPNDLIGCVIGRQGSKISEIRQMSGAHIK
                     IGNQAEGAGERHVTITGSPVSIALAQYLITACLETAKSTSGGTPGSAPADLPTPFSPP
                     LTALPTAPPGLLGTPYAISLSNFIGLKPVPFLALPPASPGPPPGLAAYTAKMAAANGS
                     KKAERQKFSPY"
     exon            302..325
                     /gene="Pcbp4"
                     /inference="alignment:Splign:2.1.0"
     exon            326..358
                     /gene="Pcbp4"
                     /inference="alignment:Splign:2.1.0"
     exon            359..475
                     /gene="Pcbp4"
                     /inference="alignment:Splign:2.1.0"
     exon            476..607
                     /gene="Pcbp4"
                     /inference="alignment:Splign:2.1.0"
     exon            608..736
                     /gene="Pcbp4"
                     /inference="alignment:Splign:2.1.0"
     exon            737..811
                     /gene="Pcbp4"
                     /inference="alignment:Splign:2.1.0"
     exon            812..856
                     /gene="Pcbp4"
                     /inference="alignment:Splign:2.1.0"
     exon            857..920
                     /gene="Pcbp4"
                     /inference="alignment:Splign:2.1.0"
     exon            921..973
                     /gene="Pcbp4"
                     /inference="alignment:Splign:2.1.0"
     exon            974..1143
                     /gene="Pcbp4"
                     /inference="alignment:Splign:2.1.0"
     exon            1144..2022
                     /gene="Pcbp4"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ccgggccggc cgggctccgc gcctgtcaaa cccctcattg ttcgcagctg atgtcactcg
       61 cagttgtgag cggccgcctt tcccggggac aatgtgggac tgagcggccc agccgccgcg
      121 ccgccgctgc cgccaccgca gaacagcccc agagagagcc agctgaacca cagcgtggac
      181 acactgcccg gccactgtgg ccccagcccc gcctgacagg atgagcagtt cagatgcggg
      241 gctggaggag gagccagagc ttagtatcac cctcaccctg cggatgctga tgcatgggaa
      301 ggaggtgggc agcatcattg ggaagaaggg agagactgta aagcgaatcc gggagcagag
      361 cagtgcccgg atcaccatct ccgagggctc ctgccctgag cgaattacca ccatcaccgg
      421 ctccacggct gccgtcttcc atgcagtctc catgatcgcc ttcaagctgg atgaggacct
      481 ttgtgctgct cctgcaaatg gtggcagtgt ctccagacct ccagtgacct tgcgccttgt
      541 catccctgcc agccagtgtg gatcactgat tgggaaggca ggtaccaaaa tcaaggagat
      601 ccgagagact acaggagccc aggtgcaggt ggcaggggac ctgcttccaa attccacaga
      661 gcgtgctgtc actgtgtctg gggtgcctga tgccatcatc ctgtgtgttc gccagatctg
      721 tgctgttatc ctggagtccc cacccaaagg agccactatc ccgtatcacc cgagcctctc
      781 cctaggcacc gtcctcctct ccgccaacca gggtttctct gtccagggtc agtatggagc
      841 agtgacccct gcagaggtca ccaagctcca gcagctctca ggccatgcag ttccctttgc
      901 gtcacccagt gtggtgccag gactggatcc cagcacgcag accagctcgc aggagtttct
      961 ggttcccaat gatctgattg gctgtgtgat cgggcgccag ggcagcaaga tcagcgagat
     1021 ccggcagatg tcaggggcac acattaagat cgggaaccaa gcggagggtg ctggggagcg
     1081 gcatgtgacc atcactggct caccggtctc cattgccctg gctcagtacc tcatcactgc
     1141 ctgtctagag acggccaagt ctacctctgg ggggacgcct ggctcagccc ccgcagacct
     1201 gcccacccct ttctcgccac ccctgacggc cctgcccaca gctcccccag gcctgctggg
     1261 cacaccttat gccatctccc tctccaactt catcggcctc aagcctgtgc ccttcctggc
     1321 tctaccacct gcttccccag ggccaccgcc gggcttggcg gcctacactg ccaagatggc
     1381 agcggccaat gggagcaaga aagctgaacg gcagaaattc tccccctact gaggccggct
     1441 gaggcacagg cgggggcagg caggaccgcc ggcaggggct gcctctacat ccttcctgcc
     1501 caaggagact ccaccacggg gtctcaagcg ccagtaatgc cagacgcatg gatgcacccc
     1561 ctaccctgcc ccatctttgg agatcctcct cagagagggg acagttcctg gcccagggtt
     1621 ctaggagttt ggcagcccca gagcaggggc tccacccctt cagacctatg cttggatgca
     1681 gggagtagct ggggcctccc cagtgccctg ccgtgggagg ggctactcgt gtcctctcca
     1741 tccctttggg cttcttcctg ctgccccagt gggaattgga ggagagtgag gggtggctgg
     1801 ggccaagctt ctcttcatcc cctgcagatc ctgctgcttc cactgatacc cttttgactg
     1861 gaatagactg gctgggcttg tccggggggc aacccaaaga gagggctctg cctatagcag
     1921 ggggtgtggc ctggggggca ggggcccagt tctcagcagc agacactctg tacagttttt
     1981 ttcaatcccc gtttttgaat aaatattctc agcgaccaga aa
//
