LOCUS       NM_001011945            2082 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus poly(rC) binding protein 3 (Pcbp3), mRNA.
ACCESSION   NM_001011945 XM_006256291 XM_215373
VERSION     NM_001011945.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2082)
  AUTHORS   Bogdan,A.R., Miyazawa,M., Hashimoto,K. and Tsuji,Y.
  TITLE     Regulators of Iron Homeostasis: New Players in Metabolism, Cell
            Death, and Disease
  JOURNAL   Trends Biochem Sci 41 (3), 274-286 (2016)
   PUBMED   26725301
  REMARK    Review article
REFERENCE   2  (bases 1 to 2082)
  AUTHORS   Lane,D.J., Merlot,A.M., Huang,M.L., Bae,D.H., Jansson,P.J.,
            Sahni,S., Kalinowski,D.S. and Richardson,D.R.
  TITLE     Cellular iron uptake, trafficking and metabolism: Key molecules and
            mechanisms and their roles in disease
  JOURNAL   Biochim Biophys Acta 1853 (5), 1130-1144 (2015)
   PUBMED   25661197
  REMARK    Review article
REFERENCE   3  (bases 1 to 2082)
  AUTHORS   Kang,D.H., Song,K.Y., Choi,H.S., Law,P.Y., Wei,L.N. and Loh,H.H.
  TITLE     Novel dual-binding function of a poly (C)-binding protein 3,
            transcriptional factor which binds the double-strand and
            single-stranded DNA sequence
  JOURNAL   Gene 501 (1), 33-38 (2012)
   PUBMED   22521865
REFERENCE   4  (bases 1 to 2082)
  AUTHORS   Castello,A., Fischer,B., Eichelbaum,K., Horos,R., Beckmann,B.M.,
            Strein,C., Davey,N.E., Humphreys,D.T., Preiss,T., Steinmetz,L.M.,
            Krijgsveld,J. and Hentze,M.W.
  TITLE     Insights into RNA biology from an atlas of mammalian mRNA-binding
            proteins
  JOURNAL   Cell 149 (6), 1393-1406 (2012)
   PUBMED   22658674
REFERENCE   5  (bases 1 to 2082)
  AUTHORS   Hu,Y.H., Warnatz,H.J., Vanhecke,D., Wagner,F., Fiebitz,A.,
            Thamm,S., Kahlem,P., Lehrach,H., Yaspo,M.L. and Janitz,M.
  TITLE     Cell array-based intracellular localization screening reveals novel
            functional features of human chromosome 21 proteins
  JOURNAL   BMC Genomics 7, 155 (2006)
   PUBMED   16780588
  REMARK    Publication Status: Online-Only
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000020.1 and BC079196.1.
            
            On or before Jun 19, 2015 this sequence version replaced
            XM_006256291.2, NM_001011945.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC079196.1, SRR26643299.66304.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760389
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-5                 JAXUCZ010000020.1  11677782-11677786
            6-2082              BC079196.1         1-2077
FEATURES             Location/Qualifiers
     source          1..2082
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="20"
                     /map="20p12"
     gene            1..2082
                     /gene="Pcbp3"
                     /note="poly(rC) binding protein 3"
                     /db_xref="GeneID:294336"
                     /db_xref="RGD:1307430"
     exon            1..152
                     /gene="Pcbp3"
                     /inference="alignment:Splign:2.1.0"
     exon            153..248
                     /gene="Pcbp3"
                     /inference="alignment:Splign:2.1.0"
     exon            249..381
                     /gene="Pcbp3"
                     /inference="alignment:Splign:2.1.0"
     CDS             372..1427
                     /gene="Pcbp3"
                     /codon_start=1
                     /product="poly(rC)-binding protein 3"
                     /protein_id="NP_001011945.2"
                     /db_xref="GeneID:294336"
                     /db_xref="RGD:1307430"
                     /translation="MGEGDAIWAPSILPHSTLSTLSHHPELHFGGKMESKVSEGGLNV
                     TLTIRLLMHGKEVGSIIGKKGETVKKMREESGARINISEGNCPERIVTITGPTDAIFK
                     AFAMIAYKFEEDIINSMSNSPATSKPPVTLRLVVPASQCGSLIGKGGSKIKEIRESTG
                     AQVQVAGDMLPNSTERAVTISGTPDAIIQCVKQICVVMLESPPKGATIPYRPKPASTP
                     VIFAGGQAYTIQGQYAIPHPDQLTKLHQLAMQQTPFPPLGQTNPAFPGLDASPPASTH
                     ELTIPNDLIGCIIGRQGTKINEIRQMSGAQIKIANATEGSSERQITITGTPANISLAQ
                     YLINARLTSEVTGMGAL"
     exon            382..536
                     /gene="Pcbp3"
                     /inference="alignment:Splign:2.1.0"
     exon            537..560
                     /gene="Pcbp3"
                     /inference="alignment:Splign:2.1.0"
     exon            561..593
                     /gene="Pcbp3"
                     /inference="alignment:Splign:2.1.0"
     exon            594..710
                     /gene="Pcbp3"
                     /inference="alignment:Splign:2.1.0"
     exon            711..842
                     /gene="Pcbp3"
                     /inference="alignment:Splign:2.1.0"
     exon            843..971
                     /gene="Pcbp3"
                     /inference="alignment:Splign:2.1.0"
     exon            972..1046
                     /gene="Pcbp3"
                     /inference="alignment:Splign:2.1.0"
     exon            1047..1088
                     /gene="Pcbp3"
                     /inference="alignment:Splign:2.1.0"
     exon            1089..1167
                     /gene="Pcbp3"
                     /inference="alignment:Splign:2.1.0"
     exon            1168..1220
                     /gene="Pcbp3"
                     /inference="alignment:Splign:2.1.0"
     exon            1221..1390
                     /gene="Pcbp3"
                     /inference="alignment:Splign:2.1.0"
     exon            1391..2057
                     /gene="Pcbp3"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gcgctgctta ccgtcgcctg agctaggaga cgccgtggcc gccgctgggt cgcctcgggc
       61 ttcgcgtcgc gccgtgtctg cctcctctgc cccacccgat cggcagcaca ggctctacct
      121 agtccgcggc ctccctgtcc gcggcggggc aggtggtttt gctgaggtga actcctgccc
      181 tgccttctgg tagctgctgc ctcctgaccc tgagctctcg gcgaacctgg gaaggggatg
      241 agaatagggt aggtgagctc cagccaagcc agccctgcca gagacctcca gttttggtgg
      301 atggtgctct gagccacagt gcacttgagc gtttggatct atggacctgc tttgaaccat
      361 agagcctgcc tatgggggaa ggtgacgcca tctgggcccc atccatcctt cctcacagta
      421 ccctcagcac cttaagccac caccctgagc tacattttgg agggaagatg gaatctaagg
      481 tctcggaagg tggcctgaac gtaaccctga ccatccgcct cctgatgcat ggaaaggaag
      541 ttggaagcat catcgggaag aaaggagaaa cagtaaagaa gatgcgtgaa gagagtggcg
      601 ccaggatcaa catctcagag ggaaactgcc cagagagaat cgtcaccatc acaggcccaa
      661 cggacgccat cttcaaggcc tttgctatga ttgcatacaa gtttgaggag gacatcatta
      721 attccatgag caacagccct gccaccagca agccccccgt gacactgcga ctagtggtcc
      781 ctgccagcca gtgtgggtcc ctgatcggca aaggtggctc caagatcaag gagatccggg
      841 agtccacagg tgctcaggtc caggtggcag gtgacatgct gcccaactcc acggagcggg
      901 cggtgactat ctcagggacc ccggacgcca tcatccagtg tgtgaaacag atctgtgtgg
      961 tcatgctgga gtccccaccg aaaggtgcca ccattcccta ccgcccaaag cccgcctcca
     1021 cccctgtcat ttttgcaggt ggtcaggcct acacaatcca gggacagtac gccatccccc
     1081 acccagatca gttgaccaag ctccaccagt tggccatgca gcaaaccccc tttcctcccc
     1141 tcggacagac caaccccgct ttccccggtc tggatgccag cccaccggcc agcactcatg
     1201 aactcaccat tcccaatgat cttataggct gcataattgg acgccaaggc accaaaatca
     1261 atgaaatccg acagatgtct ggagctcaga tcaaaatcgc caacgccact gaagggtcat
     1321 cagagcgcca gattaccatc acagggaccc cagccaacat cagcctcgcc cagtatctca
     1381 tcaacgctag gctgacgtct gaggtcactg ggatgggtgc gctctaacct ccccgagatc
     1441 ctccactgca cacatcggat ggctccagcc cgcagcctca ccagctgaca cactgtacag
     1501 actgcctgtc cttccttgca gatatgacta gagcgttttc tttacagaca ggtgatagtg
     1561 cgtgtctgcc cactcaggcc ctgtgcgctc cgtgttagtg tagcctccac gcattggcat
     1621 gcagctcttt actttaatgc tcaacgtatt cccaaatgtg atgtttcaga gatgtattcc
     1681 tcagtatcca tgtgactacc tgtttaaaag ttggtttgat gctttaacag cacttcccat
     1741 gtcctgctgc cccttgttct cagagaccct cctctcccac ccggtctact gactcattgc
     1801 caccctagat tgtccacagg gatcagaggt acttttcttg taacctgcag ggagtgtctg
     1861 gaagaggagg gacttgggga gtatctaagg agcagggtgg agtgccagag ggtggggtgg
     1921 gaccctggct tcactgggat atctcgggga gggggcgctt ggggccccca ggtgtcttcc
     1981 aaaatggcta agaacaagga cttgccagaa agttcatctg cacccatcag agtttaataa
     2041 atgtcgtgtt cctctccaaa aaaaaaaaaa aaaaaaaaaa aa
//
