LOCUS       NM_001399658            1890 bp    mRNA    linear   ROD 26-APR-2024
DEFINITION  Rattus norvegicus poly(rC) binding protein 1 (Pcbp1), mRNA.
ACCESSION   NM_001399658 XM_006236844
VERSION     NM_001399658.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1890)
  AUTHORS   Carvalho,L., Chen,H., Maienschein-Cline,M., Glover,E.J.,
            Pandey,S.C. and Lasek,A.W.
  TITLE     Conserved role for PCBP1 in altered RNA splicing in the hippocampus
            after chronic alcohol exposure
  JOURNAL   Mol Psychiatry 28 (10), 4215-4224 (2023)
   PUBMED   37537282
  REMARK    GeneRIF: Conserved role for PCBP1 in altered RNA splicing in the
            hippocampus after chronic alcohol exposure.
REFERENCE   2  (bases 1 to 1890)
  AUTHORS   Wen,W., Su,W., Tang,H., Le,W., Zhang,X., Zheng,Y., Liu,X., Xie,L.,
            Li,J., Ye,J., Dong,L., Cui,X., Miao,Y., Wang,D., Dong,J., Xiao,C.,
            Chen,W. and Wang,H.
  TITLE     Immune cell profiling of COVID-19 patients in the recovery stage by
            single-cell sequencing
  JOURNAL   Cell Discov 6, 31 (2020)
   PUBMED   32377375
  REMARK    Erratum:[Cell Discov. 2020 Jun 20;6:41. PMID: 32595980]
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 1890)
  AUTHORS   Bogdan,A.R., Miyazawa,M., Hashimoto,K. and Tsuji,Y.
  TITLE     Regulators of Iron Homeostasis: New Players in Metabolism, Cell
            Death, and Disease
  JOURNAL   Trends Biochem Sci 41 (3), 274-286 (2016)
   PUBMED   26725301
  REMARK    Review article
REFERENCE   4  (bases 1 to 1890)
  AUTHORS   Lane,D.J., Merlot,A.M., Huang,M.L., Bae,D.H., Jansson,P.J.,
            Sahni,S., Kalinowski,D.S. and Richardson,D.R.
  TITLE     Cellular iron uptake, trafficking and metabolism: Key molecules and
            mechanisms and their roles in disease
  JOURNAL   Biochim Biophys Acta 1853 (5), 1130-1144 (2015)
   PUBMED   25661197
  REMARK    Review article
REFERENCE   5  (bases 1 to 1890)
  AUTHORS   Guo,Z., Neilson,L.J., Zhong,H., Murray,P.S., Zanivan,S. and
            Zaidel-Bar,R.
  TITLE     E-cadherin interactome complexity and robustness resolved by
            quantitative proteomics
  JOURNAL   Sci Signal 7 (354), rs7 (2014)
   PUBMED   25468996
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 1890)
  AUTHORS   Li,K.W., Hornshaw,M.P., Van Der Schors,R.C., Watson,R., Tate,S.,
            Casetta,B., Jimenez,C.R., Gouwenberg,Y., Gundelfinger,E.D.,
            Smalla,K.H. and Smit,A.B.
  TITLE     Proteomics analysis of rat brain postsynaptic density. Implications
            of the diverse protein functional groups for the integration of
            synaptic physiology
  JOURNAL   J Biol Chem 279 (2), 987-1002 (2004)
   PUBMED   14532281
REFERENCE   7  (bases 1 to 1890)
  AUTHORS   Walter,B.L., Parsley,T.B., Ehrenfeld,E. and Semler,B.L.
  TITLE     Distinct poly(rC) binding protein KH domain determinants for
            poliovirus translation initiation and viral RNA replication
  JOURNAL   J Virol 76 (23), 12008-12022 (2002)
   PUBMED   12414943
REFERENCE   8  (bases 1 to 1890)
  AUTHORS   Kiledjian,M., Wang,X. and Liebhaber,S.A.
  TITLE     Identification of two KH domain proteins in the alpha-globin mRNP
            stability complex
  JOURNAL   EMBO J 14 (17), 4357-4364 (1995)
   PUBMED   7556077
REFERENCE   9  (bases 1 to 1890)
  AUTHORS   Leffers,H., Dejgaard,K. and Celis,J.E.
  TITLE     Characterisation of two major cellular poly(rC)-binding human
            proteins, each containing three K-homologous (KH) domains
  JOURNAL   Eur J Biochem 230 (2), 447-453 (1995)
   PUBMED   7607214
REFERENCE   10 (bases 1 to 1890)
  AUTHORS   Aasheim,H.C., Loukianova,T., Deggerdal,A. and Smeland,E.B.
  TITLE     Tissue specific expression and cDNA structure of a human transcript
            encoding a nucleic acid binding [oligo(dC)] protein related to the
            pre-mRNA binding protein K
  JOURNAL   Nucleic Acids Res 22 (6), 959-964 (1994)
   PUBMED   8152927
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000004.1.
            
            On Jan 12, 2022 this sequence version replaced XM_006236844.3.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on transcript alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR22399484.1250276.1,
                                           SRR26643285.16860.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-140               JAXUCZ010000004.1  120531968-120532107 c
            141-1890            JAXUCZ010000004.1  120530100-120531849 c
FEATURES             Location/Qualifiers
     source          1..1890
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="4"
                     /map="4q34"
     gene            1..1890
                     /gene="Pcbp1"
                     /gene_synonym="RGD1561319"
                     /note="poly(rC) binding protein 1"
                     /db_xref="GeneID:500242"
                     /db_xref="RGD:1561319"
     exon            1..140
                     /gene="Pcbp1"
                     /gene_synonym="RGD1561319"
                     /inference="alignment:Splign:2.1.0"
     exon            141..1890
                     /gene="Pcbp1"
                     /gene_synonym="RGD1561319"
                     /inference="alignment:Splign:2.1.0"
     CDS             474..1544
                     /gene="Pcbp1"
                     /gene_synonym="RGD1561319"
                     /codon_start=1
                     /product="poly(rC)-binding protein 1"
                     /protein_id="NP_001386587.1"
                     /db_xref="GeneID:500242"
                     /db_xref="RGD:1561319"
                     /translation="MDAGVTESGLNVTLTIRLLMHGKEVGSIIGKKGESVKRIREESG
                     ARINISEGNCPERIITLTGPTNAIFKAFAMIIDKLEEDINSSMTNSTAASRPPVTLRL
                     VVPATQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERAITIAGVPQSVTECVK
                     QICLVMLETLSQSPQGRVMTIPYQPMPASSPVICAGGQDRCSDAAGYPHATHDLEGPP
                     LDAYSIQGQHTISPLDLAKLNQVARQQSHFAMMHGGTGFAGIDSSSPEVKGYWASLDA
                     STQTTHELTIPNNLIGCIIGRQGANINEIRQMSGAQIKIANPVEGSSGRQVTITGSAA
                     SISLAQYLINARLSSEKGMGCS"
ORIGIN      
        1 gctccgcgat cgaactcttc ggcggagcga gaaaatatta tctgtctccg tcacagagta
       61 gtaactgtcc cagtctcctg ccggtgcctc tagagttaac aaaaacacgt gcttcctctc
      121 aatctttgcc ggattctcag gggtcctgcg cggaaagcac ttccggggtc agagggtacg
      181 cggggttgaa agcgggcttc ccgccccgcc cagaccgccg aggctgccgc cggagtcgcc
      241 accgccgcgc cctcgcccac ccgcccgtcc gccgctcccg gccccgctcg cccccgccgc
      301 tgctgccgct cgtcctgcga cgccgccgcg gcctcccgcc cgcgcccgcc cgctcccgcg
      361 gcccccgctc gcctcgcgcc ggcagttcgg gcctactcct cccctccccc gccagccgcc
      421 caggacttga ccacgtaacg agcccaactc ccgaacgccg cccgccgctc gccatggacg
      481 ccggtgtgac tgaaagcgga ctcaacgtga ctctcaccat tcggctgctg atgcacggaa
      541 aggaagtagg cagcatcatc gggaagaaag gggagtcggt gaagaggatc cgcgaggaga
      601 gcggcgcgcg gatcaacatc tcggagggga actgcccgga gagaatcatc acgctgactg
      661 ggcccaccaa tgccatcttt aaggccttcg ccatgatcat cgacaagctg gaggaagata
      721 tcaacagctc catgaccaac agtacggcgg ccagcaggcc cccggtcact cttcggctgg
      781 tggtgcccgc cacccagtgt ggctccctga tcggcaaggg cggctgcaag atcaaggaga
      841 tccgcgagag cacgggggcc caggtccagg tggcggggga tatgctgccc aactcgaccg
      901 agcgggctat cactatcgcc ggcgtgccgc agtcggtcac cgagtgtgtt aagcagatct
      961 gcctggtcat gctggagacg ctctcccagt ctccgcaagg gagagtcatg accatcccgt
     1021 accagcccat gccggccagt tcgccagtca tctgcgcggg cggccaagat cgctgcagcg
     1081 acgcggcggg ctatccccac gccacccacg acctggaggg accacctcta gacgcctact
     1141 cgattcaagg acaacacacc atttctccgc tggatctggc caagctgaac caggtggcaa
     1201 gacaacagtc tcactttgcc atgatgcacg gcgggacggg attcgccgga attgactcca
     1261 gctctccaga ggtgaaaggc tattgggcaa gtttggatgc atctactcaa accacccatg
     1321 aactcaccat tccaaataac ttaatcggct gcataatcgg gcgccaaggc gccaacatca
     1381 atgagatccg ccagatgtcc ggggcccaga tcaaaattgc caacccagtg gaaggctctt
     1441 ctggaaggca ggtcactatt actggctccg ctgccagtat tagcctggcc cagtatctaa
     1501 tcaatgccag gctttcctct gagaagggca tggggtgcag ctagaacagt gtaggttcgc
     1561 tcgtaacccc cttctgctgt tttcccatga tccaactgtg taatttctgg tcagtgattc
     1621 caggttttaa ataatttgta agtgttcagt ttctacactt tatcatccgc taagaattta
     1681 aagaaaaatc acattctctg ttcagctgtt aatgctggga tccatattta gttttataag
     1741 cttttccctg tttttagttt cgtttgggtt tttggctcat ggattttatt ttctgtttgt
     1801 cgaaaaatgt aagagtggaa tgttaataaa tttcagttta gttctgtaat gtcaagaatt
     1861 taagaattaa aaaaatggat tggttaaaaa
//
