LOCUS       NM_001191984            5185 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus paired box 7 (Pax7), mRNA.
ACCESSION   NM_001191984 XM_575941
VERSION     NM_001191984.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 5185)
  AUTHORS   Bi,J., Jing,H., Zhou,C., Gao,P., Han,F., Li,G. and Zhang,S.
  TITLE     Regulation of skeletal myogenesis in C2C12 cells through modulation
            of Pax7, MyoD, and myogenin via different low-frequency
            electromagnetic field energies
  JOURNAL   Technol Health Care 30 (S1), 371-382 (2022)
   PUBMED   35124612
  REMARK    GeneRIF: Regulation of skeletal myogenesis in C2C12 cells through
            modulation of Pax7, MyoD, and myogenin via different low-frequency
            electromagnetic field energies.
REFERENCE   2  (bases 1 to 5185)
  AUTHORS   Choo,H.J., Cutler,A., Rother,F., Bader,M. and Pavlath,G.K.
  TITLE     Karyopherin Alpha 1 Regulates Satellite Cell Proliferation and
            Survival by Modulating Nuclear Import
  JOURNAL   Stem Cells 34 (11), 2784-2797 (2016)
   PUBMED   27434733
REFERENCE   3  (bases 1 to 5185)
  AUTHORS   Budry,L., Balsalobre,A., Gauthier,Y., Khetchoumian,K., L'honore,A.,
            Vallette,S., Brue,T., Figarella-Branger,D., Meij,B. and Drouin,J.
  TITLE     The selector gene Pax7 dictates alternate pituitary cell fates
            through its pioneer action on chromatin remodeling
  JOURNAL   Genes Dev 26 (20), 2299-2310 (2012)
   PUBMED   23070814
REFERENCE   4  (bases 1 to 5185)
  AUTHORS   Diao,Y., Guo,X., Li,Y., Sun,K., Lu,L., Jiang,L., Fu,X., Zhu,H.,
            Sun,H., Wang,H. and Wu,Z.
  TITLE     Pax3/7BP is a Pax7- and Pax3-binding protein that regulates the
            proliferation of muscle precursor cells by an epigenetic mechanism
  JOURNAL   Cell Stem Cell 11 (2), 231-241 (2012)
   PUBMED   22862948
REFERENCE   5  (bases 1 to 5185)
  AUTHORS   Cheung,T.H., Quach,N.L., Charville,G.W., Liu,L., Park,L.,
            Edalati,A., Yoo,B., Hoang,P. and Rando,T.A.
  TITLE     Maintenance of muscle stem-cell quiescence by microRNA-489
  JOURNAL   Nature 482 (7386), 524-528 (2012)
   PUBMED   22358842
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 5185)
  AUTHORS   Seale,P., Sabourin,L.A., Girgis-Gabardo,A., Mansouri,A., Gruss,P.
            and Rudnicki,M.A.
  TITLE     Pax7 is required for the specification of myogenic satellite cells
  JOURNAL   Cell 102 (6), 777-786 (2000)
   PUBMED   11030621
REFERENCE   7  (bases 1 to 5185)
  AUTHORS   Mansouri,A. and Gruss,P.
  TITLE     Pax3 and Pax7 are expressed in commissural neurons and restrict
            ventral neuronal identity in the spinal cord
  JOURNAL   Mech Dev 78 (1-2), 171-178 (1998)
   PUBMED   9858722
REFERENCE   8  (bases 1 to 5185)
  AUTHORS   Kay,P.H., Harmon,D., Fletcher,S., Robertson,T., Ziman,M. and
            Papadimitriou,J.M.
  TITLE     Pax7 includes two polymorphic homeoboxes which contain
            rearrangements associated with differences in the ability to
            regenerate damaged skeletal muscle in adult mice
  JOURNAL   Int J Biochem Cell Biol 30 (2), 261-269 (1998)
   PUBMED   9608680
REFERENCE   9  (bases 1 to 5185)
  AUTHORS   Ericson,J., Rashbass,P., Schedl,A., Brenner-Morton,S., Kawakami,A.,
            van Heyningen,V., Jessell,T.M. and Briscoe,J.
  TITLE     Pax6 controls progenitor cell identity and neuronal fate in
            response to graded Shh signaling
  JOURNAL   Cell 90 (1), 169-180 (1997)
   PUBMED   9230312
REFERENCE   10 (bases 1 to 5185)
  AUTHORS   Mansouri,A., Stoykova,A., Torres,M. and Gruss,P.
  TITLE     Dysgenesis of cephalic neural crest derivatives in Pax7-/- mutant
            mice
  JOURNAL   Development 122 (3), 831-838 (1996)
   PUBMED   8631261
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000005.1.
            
            On Sep 13, 2022 this sequence version replaced NM_001191984.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR22582416.673328.1,
                                           SRR26360172.2138945.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760386, SAMEA5760475
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-120               JAXUCZ010000005.1  157381002-157381121 c
            121-356             JAXUCZ010000005.1  157378306-157378541 c
            357-486             JAXUCZ010000005.1  157377686-157377815 c
            487-615             JAXUCZ010000005.1  157376788-157376916 c
            616-815             JAXUCZ010000005.1  157327259-157327458 c
            816-981             JAXUCZ010000005.1  157323822-157323987 c
            982-1184            JAXUCZ010000005.1  157322646-157322848 c
            1185-1431           JAXUCZ010000005.1  157291761-157292007 c
            1432-5185           JAXUCZ010000005.1  157279623-157283376 c
FEATURES             Location/Qualifiers
     source          1..5185
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="5"
                     /map="5q36"
     gene            1..5185
                     /gene="Pax7"
                     /gene_synonym="RGD1564360"
                     /note="paired box 7"
                     /db_xref="GeneID:500574"
                     /db_xref="RGD:1564360"
     exon            1..120
                     /gene="Pax7"
                     /gene_synonym="RGD1564360"
                     /inference="alignment:Splign:2.1.0"
     CDS             36..1547
                     /gene="Pax7"
                     /gene_synonym="RGD1564360"
                     /note="paired box gene 7"
                     /codon_start=1
                     /product="paired box protein Pax-7"
                     /protein_id="NP_001178913.1"
                     /db_xref="GeneID:500574"
                     /db_xref="RGD:1564360"
                     /translation="MAALPGAVPRMMRPGPGQNYPRTGFPLEVSTPLGQGRVNQLGGV
                     FINGRPLPNHIRHKIVEMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIRPGAIG
                     GSKPRQVATPDVEKKIEEYKRENPGMFSWEIRDRLLKDGHCDRSTVPSVSSISRVLRI
                     KFGKKEDDEEGDKKEEDGEKKAKHSIDGILGDKGNRLDEGSDVESEPDLPLKRKQRRS
                     RTTFTAEQLEELEKAFERTHYPDIYTREELAQRTKLTEARVQVWFSNRRARWRKQAGA
                     NQLAAFNHLLPGGFPPTGMPTLPPYQLPDSAYPTTTVSQDGGSTVHRPQPLPPSTMHQ
                     GGLAAAAAAADSSSAYGARHSFSSYSDSFMNPGAPSNHMNPVSNGLSPQVMSILSNPS
                     AVPPQPQADFSISPLHGGLDSASSISASCSQRADSIKPGDSLPTSQSYCPPTYSTTGY
                     SVDPVAGYQYSQYGQTAVDYLAKNVSLSTQRRMKLGEHSAVLGLLPVETGQAY"
     exon            121..356
                     /gene="Pax7"
                     /gene_synonym="RGD1564360"
                     /inference="alignment:Splign:2.1.0"
     exon            357..486
                     /gene="Pax7"
                     /gene_synonym="RGD1564360"
                     /inference="alignment:Splign:2.1.0"
     exon            487..615
                     /gene="Pax7"
                     /gene_synonym="RGD1564360"
                     /inference="alignment:Splign:2.1.0"
     exon            616..815
                     /gene="Pax7"
                     /gene_synonym="RGD1564360"
                     /inference="alignment:Splign:2.1.0"
     exon            816..981
                     /gene="Pax7"
                     /gene_synonym="RGD1564360"
                     /inference="alignment:Splign:2.1.0"
     exon            982..1184
                     /gene="Pax7"
                     /gene_synonym="RGD1564360"
                     /inference="alignment:Splign:2.1.0"
     exon            1185..1431
                     /gene="Pax7"
                     /gene_synonym="RGD1564360"
                     /inference="alignment:Splign:2.1.0"
     exon            1432..5185
                     /gene="Pax7"
                     /gene_synonym="RGD1564360"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 agccgactct ggattcgtct ccggcgtgcg caggaatggc ggcgctgccc ggcgcggtcc
       61 ccaggatgat gagacccggc ccggggcaga actacccgcg caccggcttc cccctggaag
      121 tgtccacccc tcttggccaa ggccgggtca atcagcttgg tggggtcttc atcaacgggc
      181 gacccctgcc gaaccatatc cggcacaaga tagtggaaat ggcccaccac ggcatccggc
      241 cctgcgtcat ctcccgtcag ctccgcgtat cccatggctg tgtctccaag attctgtgcc
      301 ggtaccagga gactgggtcc atccggcccg gggccatcgg tggcagcaag cccagacagg
      361 tggcgactcc ggatgtggag aaaaagattg aggagtataa gagggagaac cccggaatgt
      421 tcagctggga aatccgggac cggctgctga aggacggcca ctgtgaccgc agcacggtgc
      481 cctcagtgag ttcgattagc cgagtgctca gaatcaagtt cgggaagaaa gaggacgatg
      541 aggaaggaga caaaaaggaa gaagatggcg agaagaaagc caaacacagc atcgatggca
      601 tcctgggcga caaaggcaac cgtcttgatg aaggctcgga cgtggaatca gaacccgacc
      661 tcccactgaa gcgtaagcag cgtcgcagtc ggaccacatt cacggctgag cagctggagg
      721 agctggagaa ggctttcgag aggacccact acccggacat ctacacccgg gaggagctgg
      781 cacagaggac caagctcacg gaggcacgcg tccaggtctg gttcagtaac cgtcgtgcgc
      841 gctggcgcaa gcaggcaggc gctaaccagc tggccgcctt caaccacctt ctgccgggag
      901 gtttcccacc cactggtatg cccacgctgc caccctacca gctgccggac tctgcctatc
      961 ccaccaccac cgtctcccaa gatgggggca gcacagtaca caggccccag ccccttccgc
     1021 catcaaccat gcatcagggt gggctggctg cggccgctgc agcagctgac agcagctctg
     1081 cctacggagc ccgccacagc ttctccagct actcggacag cttcatgaac cccggggccc
     1141 cctccaacca catgaacccc gtcagcaatg gcctgtctcc tcaggtgatg agcattctca
     1201 gcaacccgag tgctgtgcct ccacagcccc aggccgactt ctccatctcc ccgctgcatg
     1261 gaggtctgga ctctgcctcc tccatctcag ccagttgcag ccagcgggcc gactccatca
     1321 agccaggaga cagcttgccc acctcccagt cttactgccc acccacctac agcaccacgg
     1381 gctacagtgt ggaccctgtg gctggttacc agtacagcca gtacggtcaa actgctgttg
     1441 attacctggc caaaaacgtg agcctgtcta cacagcgccg tatgaagctc ggggaacact
     1501 ccgcggtgct gggacttctt cctgtggaga cgggacaagc ctactagggt ccctggggca
     1561 acttgcccta tccagtgacc cagcttagcc cttcccaaac cctgagtctc ctccccttat
     1621 ccccctgggg tcgcaggagg ccagggaaga aaccctctcc cttcctacag gcagccctct
     1681 ggagacggac aaccagtgcg ccaatcactc atggttaatg acctagattg gctttctgcc
     1741 tccccctctt tctccagagg ggttcctcac cattctgcag tgacctccag ctcagaccca
     1801 cctcctagtg tcatggcctt ggtcctgtct cagtgtagag attgagactc aagttgaacc
     1861 aagcacctag ctatcagagg aaaatggtgc caaagacaag gccctggagt ctttgacctc
     1921 tgagtcctgg gtgcccggcc acaggtgcag gtggagctca tgggtgtcct cagtcacaga
     1981 gctgggagct ctctcttgct tggcatcagc actgcagtcc ctttcactgg acactgacat
     2041 gagtcccaag ggcgttccca agggagaaag caggaaacat ctcagcttta cctgggaatc
     2101 cagaggactt tgggactgtc cctatgcacc ctgctgcaaa tcaggagacc aggaattcta
     2161 gcagagggta gggtgcacag agcttgctgg ccatgagcta tctcagaatg cctggtctca
     2221 ggtccagcag caggaggtgc aggactccta agttgcaatc tgacagaggc ttgcccaccg
     2281 taccaggtct aggcagccca cagaacctgt cagtctcctc aactggtagg agaagagaag
     2341 gtcttgaggt gacaggaggc aggaggtggg ctcagacagt ctgagttgag ctttcaagtc
     2401 tgcaccccta gagttctgca caccatcttg ctggcagctg ggaacctgcc tcatgcatgc
     2461 tggtcccctg aaaagggggc ctccatcttc cagcatgtaa ggctcttgat gccactggat
     2521 gcagagagcc ttctcggacc agacaaaatt attgatccac accagagaag atgctcccca
     2581 tctccttggc atcgccttgt ctctgtcctt ttcggagtag catttttcaa tgttggttgc
     2641 tcagtcagga ggcttctgtc gcctcacgag gcatagtgcg ccttgggcca ccacccaccc
     2701 cctggcagag gaagatgcca gaagtcccag caatgaggac aaggcgcctt ccttaaacac
     2761 tccagagtct tccttgcact cccgccctct cttagagctg ggtcttttgg ggtaaatgga
     2821 ttgctgaggc ccctgattct ctcctctgtg gaggtcttta tcaccatcta tttatcaaga
     2881 ttacatccac tttgaccttc tccctcgcta taacctccac ttgggccatc ctcatccagt
     2941 gctaggatcc cacagcacca aatccaggat ccctgggcct gattgcttgt tgccaccatg
     3001 cacacgagac cacctgctga cgcagtccat gcctcctggc ctcagccatc gagacattcc
     3061 tagagagatg ggctatgggc tcaaaagccc tgacttcctt ttgactgggg acctgaaccg
     3121 gcaagatgct gggacactcg tctacatgaa catgtgacca atgtatctca tctctagagc
     3181 catcatctga agcctattcc aagctgtgac tgggatggct tgtatctgtg gtttagagaa
     3241 gcctattcgt aactgggagg aaactggctc tctggcatcc tggagcacca gacatataga
     3301 gcttatccgt tcagtccagg cttcaaggaa gacttttggg ctcttcaagg tctggacaag
     3361 agggaagcca tgttgccccc cttggaaacc cagattctcc ttttgaagtt cttatagctg
     3421 caagcacctc tttcagaaga ccaaatgcat cttcctccac attccttgcc ccttggaggc
     3481 ctggctctgg atacacctga gtctcctttc accaagtatg cttcaggacc agggacctca
     3541 agcaggtgac atccacaggg cccagtctca gccccaggag caacattcca atgcttggac
     3601 caatcacaat gatctgccca caagggtaac cgcaaccaga gacctgcttg cgagaaaatg
     3661 aaatgacttc tcattccatg caacgtctct gaatgctccc ccaagccgcc atcttggtat
     3721 aaaatgggac ttgtgttctg aggggccctt gaccccaaca gatttcccca accgtctcat
     3781 gcttttgtga atctgtccac cttgatctgt aaaactcagc cttgttgggg caacttgcaa
     3841 ctgcaccatt gaggtgatga aggttaggcg agaggtacca ggcctctccc ctgtccctct
     3901 ggggttgagc acagcctaca aaggccgatt tccagtggcc aggctggatc agaaacagcc
     3961 cccaccccaa ctcctgtaaa tagaatcaat agtaagataa gaggggtgcc ctccatgtca
     4021 cctcaagtag ctactggttc ttctgtgggg gcccctctga acttattgta tggtagttga
     4081 tgtgacgtcg tgccgtttgt ttatagaaca ttggcttttt atatataaat ctatatactt
     4141 aaaaacaaaa caaaaacaaa aaaatggaaa gaaaccccca cagtgcgtgt cgtgctagtg
     4201 ccagggatca tctgtaggga tctcactgtg tgtttgggtt acgaattcca gcctctcttt
     4261 gattccttct tctttttccc tttgtcattt ccctactccc aatttggctt ttctctcttg
     4321 ctatgaaatt gaaagagaag gcttcaagag ccaagcatct actcctttat actcgtttta
     4381 actttgccct tcttttaggg gaccaggaag gaacgagcac aggaaacaga cattgggaag
     4441 caagagggta ggagagaaaa gtgaggggag gagctggccg gggagacagg agagcagggc
     4501 agtttcacag ccagatgatg ggtgcagccc aggacggagg ctggattggt atctgcacca
     4561 gagtcgggca ttgttttgca tggaaatcgt agaaggttct aagacgtgga actaagggac
     4621 tccacagttg ccaactaaaa agactgtgca agtcctctat gagactcatt cttcccaggc
     4681 tcctggaaat gtctctccct gctggatgct tctctaggct acacagcatc ctcaccttct
     4741 acagaagacg caccaagcca agaccaaatg ggggtatgtg ggctgccgcg ttgaaatgct
     4801 tcgagatacc tgtgcgttta atgtttcctc tgtctacacg gacctgggca gcccccagct
     4861 gggagaatac cacactgtgc tggagaacat tccttctacc tagtgactgc aacattgttg
     4921 cttcagtgtt tggctcagcc atttctctcc aggcaaagtg agtgtgtgtg catgaggggt
     4981 gtgagtggaa tgtgcgtgtg tgggcgggtg tctaaatata accgcaccat aatttattca
     5041 gctatatgga gtagtagact agaaagacaa actggtattt gctttaacta cctgctgctt
     5101 gtaagcgctg cctctgtaac tcaggcgtaa ctgttacaca ttaaaagaaa ttaaaaaaaa
     5161 aaaaaaacat cgtgaaggtt ctgca
//
