LOCUS       NM_001134780            1997 bp    mRNA    linear   ROD 27-MAR-2024
DEFINITION  Rattus norvegicus parvin, beta (Parvb), mRNA.
ACCESSION   NM_001134780 XM_343303
VERSION     NM_001134780.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1997)
  AUTHORS   Nicholson,L., Madawala,R., Lindsay,L. and Murphy,C.R.
  TITLE     alpha-Parvin and beta-parvin in the rat uterus during
            decidualisation and uterine receptivity
  JOURNAL   Histochem Cell Biol 151 (5), 395-406 (2019)
   PUBMED   30515554
  REMARK    GeneRIF: The beta-parvin acts in opposition; significantly
            increasing in both UECs and ESCs at the time of implantation,
            suggesting a role in the process of decidualisation.
REFERENCE   2  (bases 1 to 1997)
  AUTHORS   Stiegler,A.L., Draheim,K.M., Li,X., Chayen,N.E., Calderwood,D.A.
            and Boggon,T.J.
  TITLE     Structural basis for paxillin binding and focal adhesion targeting
            of beta-parvin
  JOURNAL   J Biol Chem 287 (39), 32566-32577 (2012)
   PUBMED   22869380
REFERENCE   3  (bases 1 to 1997)
  AUTHORS   Matsuda,C., Kameyama,K., Suzuki,A., Mishima,W., Yamaji,S.,
            Okamoto,H., Nishino,I. and Hayashi,Y.K.
  TITLE     Affixin activates Rac1 via betaPIX in C2C12 myoblast
  JOURNAL   FEBS Lett 582 (8), 1189-1196 (2008)
   PUBMED   18325335
REFERENCE   4  (bases 1 to 1997)
  AUTHORS   Legate,K.R., Montanez,E., Kudlacek,O. and Fassler,R.
  TITLE     ILK, PINCH and parvin: the tIPP of integrin signalling
  JOURNAL   Nat Rev Mol Cell Biol 7 (1), 20-31 (2006)
   PUBMED   16493410
  REMARK    Review article
REFERENCE   5  (bases 1 to 1997)
  AUTHORS   Mishima,W., Suzuki,A., Yamaji,S., Yoshimi,R., Ueda,A., Kaneko,T.,
            Tanaka,J., Miwa,Y., Ohno,S. and Ishigatsubo,Y.
  TITLE     The first CH domain of affixin activates Cdc42 and Rac1 through
            alphaPIX, a Cdc42/Rac1-specific guanine nucleotide exchanging
            factor
  JOURNAL   Genes Cells 9 (3), 193-204 (2004)
   PUBMED   15005707
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from
            JAXUCZ010000007.1.
            
            On Sep 5, 2008 this sequence version replaced XM_343303.3.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643289.21637.1,
                                           SRR26643298.41438.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-144               JAXUCZ010000007.1  117240238-117240381
            145-234             JAXUCZ010000007.1  117279201-117279290
            235-305             JAXUCZ010000007.1  117281337-117281407
            306-408             JAXUCZ010000007.1  117288564-117288666
            409-549             JAXUCZ010000007.1  117299380-117299520
            550-665             JAXUCZ010000007.1  117301585-117301700
            666-724             JAXUCZ010000007.1  117304304-117304362
            725-744             JAXUCZ010000007.1  117308659-117308678
            745-806             JAXUCZ010000007.1  117314145-117314206
            807-875             JAXUCZ010000007.1  117314602-117314670
            876-977             JAXUCZ010000007.1  117319221-117319322
            978-1050            JAXUCZ010000007.1  117322919-117322991
            1051-1997           JAXUCZ010000007.1  117323137-117324083
FEATURES             Location/Qualifiers
     source          1..1997
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="7"
                     /map="7q34"
     gene            1..1997
                     /gene="Parvb"
                     /note="parvin, beta"
                     /db_xref="GeneID:362973"
                     /db_xref="RGD:1311485"
     exon            1..144
                     /gene="Parvb"
                     /inference="alignment:Splign:2.1.0"
     CDS             30..1127
                     /gene="Parvb"
                     /codon_start=1
                     /product="beta-parvin"
                     /protein_id="NP_001128252.1"
                     /db_xref="GeneID:362973"
                     /db_xref="RGD:1311485"
                     /translation="MSSALPRSPTPRAPKMKKDESFLGKLGGTLARKKKTREVTDLQE
                     EGKSAINSPMAPALVDIHPEDTQLEENEERTMIDPTSREDPKFKELVKVLLDWINDVL
                     AEERIIVKQLEEDLYDGQVLQKLLEKLAHCKLNVAEVTQSEIGQKQKLQTVLEAVQDL
                     LRPHGWPLRWNVDSIHGKNLVSILHLLVSLAMHFRAPIHLPEHVTVQVVVVRKREGLL
                     HSSHISEELTTTTEIMMGRFERDAFDTLFDHAPDKLNLVKKSLITFVNKHLNKLNLEV
                     TDLETQFADGVYLVLLLGLLEDYFVPLHNFYLTPDSFDQKVHNVAFAFELMLDGGLKK
                     PKARPEDVVNLDLKSTLRVLYTLFTKYKDVE"
     exon            145..234
                     /gene="Parvb"
                     /inference="alignment:Splign:2.1.0"
     exon            235..305
                     /gene="Parvb"
                     /inference="alignment:Splign:2.1.0"
     exon            306..408
                     /gene="Parvb"
                     /inference="alignment:Splign:2.1.0"
     exon            409..549
                     /gene="Parvb"
                     /inference="alignment:Splign:2.1.0"
     exon            550..665
                     /gene="Parvb"
                     /inference="alignment:Splign:2.1.0"
     exon            666..724
                     /gene="Parvb"
                     /inference="alignment:Splign:2.1.0"
     exon            725..744
                     /gene="Parvb"
                     /inference="alignment:Splign:2.1.0"
     exon            745..806
                     /gene="Parvb"
                     /inference="alignment:Splign:2.1.0"
     exon            807..875
                     /gene="Parvb"
                     /inference="alignment:Splign:2.1.0"
     exon            876..977
                     /gene="Parvb"
                     /inference="alignment:Splign:2.1.0"
     exon            978..1050
                     /gene="Parvb"
                     /inference="alignment:Splign:2.1.0"
     exon            1051..1997
                     /gene="Parvb"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ggccggcggt gggtggtgcg cactcgctta tgtcctccgc gctaccacga tcgcccaccc
       61 cgcgggcccc caagatgaag aaggacgagt ctttcttggg caagttgggc ggcacactgg
      121 caaggaagaa gaagaccagg gaggtgaccg acttgcagga agaaggcaag agcgccatca
      181 attctccaat ggccccggct ttggtggaca ttcaccctga agacacccag ctagaggaga
      241 atgaggagcg caccatgatc gatcccacct ctagagaaga ccccaagttc aaggagttgg
      301 tcaaggtgct tctggactgg atcaacgacg tgctggcaga ggagcgcatc attgtgaagc
      361 agctggagga ggacctgtac gatggccagg tgctacagaa acttctggaa aagctggcac
      421 actgcaagct gaatgtggca gaggtgacgc agtctgagat cgggcagaag cagaagttgc
      481 agacagttct ggaagccgtg caagacctgc tccggcccca cggctggccg ctgcgttgga
      541 atgtggactc tatccacggg aagaacctgg tgtccattct gcacctcctc gtctccctgg
      601 ccatgcactt cagggccccc atccaccttc ctgaacacgt caccgtgcag gtggtggtcg
      661 tccggaagcg ggaaggcctg ctgcactcca gccacatctc agaggagctg accacgacca
      721 cagagatcat gatgggccgg tttgagcggg atgccttcga cacgctcttc gaccacgcgc
      781 cggacaagct caaccttgtg aagaagtctc tcatcacgtt tgtgaacaaa cacctgaaca
      841 agctaaactt ggaggtcact gacctggaga cccagtttgc agatggtgtg tacctggttc
      901 tactcctggg cctccttgaa gactactttg tccccctcca caacttctac ctgactcctg
      961 acagctttga ccagaaggtg cacaacgtgg cctttgcctt tgaactgatg ctggacgggg
     1021 gactcaagaa gcccaaggca cgccctgaag acgtcgtgaa cttggacctc aagtccactc
     1081 tgcgggtcct ttacacactg ttcaccaagt acaaggacgt cgagtgacag agcagccggt
     1141 tcttcaggga caagttttag acaagaaaaa aatggtcgtg tccatccaca gtccctgatt
     1201 tcccaggaac cgtctcctca gggaggcctc aggcttccca ggtctagctg tgtaatgcct
     1261 ctgctctctg ctccctgcct ggtttggttt taaacccttt tcccttgtgg ttccctagct
     1321 gattagatca ttgagaactt ggtgcttcaa acacccactc cagtttgagg cctcacttcc
     1381 tctttttctc tgcctcccct gaagatgaaa gagaacaaag gcccagccta gccctcagct
     1441 ggaaagggct gtccacctgt gctccaaccc acggagcaat tacagcaaca gccctggctc
     1501 cagggactcc gccccatttg tcctcaggaa tcccctgggc tgggctctcc ctggaagcag
     1561 ggtctcgcct cagtaaaaag atcctctcgg gtttttttct ttcctgaatc tcagaagatt
     1621 tagactcctg acatgtgtct ccacccccat cctgtcttgc ggtttgctga tttttaactg
     1681 accttttaca tgaactctca ggacccagaa tgccttgggg ccccagggca gcttgtacaa
     1741 gggcatgtct gggtctcttg ctggctctga acatgcagct tgagccggct cggagttgga
     1801 accttccatc tctgaggccc tgttagggaa tggatacatt tttagagact ttacaagagg
     1861 gagggaatcc attatgaggg ctgcctgacc acaggctacc ggcagccaga attacagagg
     1921 cgtgcgtctg gcagctctgg aggctgagag taggagacag aggtgctggc aggttgcctc
     1981 tctctgcctt cacacca
//
