LOCUS       NM_001014064            3292 bp    mRNA    linear   ROD 22-SEP-2024
DEFINITION  Rattus norvegicus prolyl-tRNA synthetase 2, mitochondrial (Pars2),
            mRNA; nuclear gene for mitochondrial product.
ACCESSION   NM_001014064 XM_233267
VERSION     NM_001014064.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3292)
  AUTHORS   Morgenstern,M., Peikert,C.D., Lubbert,P., Suppanz,I., Klemm,C.,
            Alka,O., Steiert,C., Naumenko,N., Schendzielorz,A., Melchionda,L.,
            Muhlhauser,W.W.D., Knapp,B., Busch,J.D., Stiller,S.B.,
            Dannenmaier,S., Lindau,C., Licheva,M., Eickhorst,C., Galbusera,R.,
            Zerbes,R.M., Ryan,M.T., Kraft,C., Kozjak-Pavlovic,V., Drepper,F.,
            Dennerlein,S., Oeljeklaus,S., Pfanner,N., Wiedemann,N. and
            Warscheid,B.
  TITLE     Quantitative high-confidence human mitochondrial proteome and its
            dynamics in cellular context
  JOURNAL   Cell Metab 33 (12), 2464-2483 (2021)
   PUBMED   34800366
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000005.1.
            
            On Mar 11, 2021 this sequence version replaced NM_001014064.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC088403.1, SRR26360186.604183.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760386, SAMEA5760389
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            gene product(s) localized to mito. :: inferred from homology
            RefSeq Select criteria             :: based on conservation,
                                                  expression, longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-46                JAXUCZ010000005.1  126662919-126662964
            47-3292             JAXUCZ010000005.1  126664736-126667981
FEATURES             Location/Qualifiers
     source          1..3292
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="5"
                     /map="5q34"
     gene            1..3292
                     /gene="Pars2"
                     /gene_synonym="RGD1305345"
                     /note="prolyl-tRNA synthetase 2, mitochondrial"
                     /db_xref="GeneID:313429"
                     /db_xref="RGD:1305345"
     exon            1..46
                     /gene="Pars2"
                     /gene_synonym="RGD1305345"
                     /inference="alignment:Splign:2.1.0"
     exon            47..3292
                     /gene="Pars2"
                     /gene_synonym="RGD1305345"
                     /inference="alignment:Splign:2.1.0"
     CDS             205..1647
                     /gene="Pars2"
                     /gene_synonym="RGD1305345"
                     /EC_number="6.1.1.15"
                     /note="probable prolyl-tRNA synthetase, mitochondrial;
                     proRS; proline--tRNA ligase; prolyl-tRNA synthetase
                     (mitochondrial)(putative); probable proline--tRNA ligase,
                     mitochondrial; prolyl-tRNA synthetase 2, mitochondrial
                     (putative)"
                     /codon_start=1
                     /product="probable proline--tRNA ligase, mitochondrial
                     precursor"
                     /protein_id="NP_001014086.2"
                     /db_xref="GeneID:313429"
                     /db_xref="RGD:1305345"
                     /translation="MYQGIMEGLLTRCRTLSALATCSLRHSRCIVRKCYHCAPGRGQR
                     LVVSRMFQPQNLREDQVLSLEGRASDLTCKSQRLMLQVGLILPASPGCYHLMPYTVRA
                     VEKLVRVIDQEMQAIGGQKINMPSLSPAELWRATGRWDLMGRELLRLKDRHGKEYCLG
                     PTHEEAVTALVASQKKLSYKQLPLLLYQVTRKFRDEPRPRFGLLRGREFYMKDMYTFD
                     SSSEAAQETYSLVCDAYCRLFDRLGLRWMKARADVGSIGGTMSHEFQLPVDIGEDRLV
                     VCPSCHFSANTEIVDLSQKICPDCQGPLTETKGIEVGHTFYLGTKYSSIFNAHFTNAH
                     GESLLAEMGCYGLGVTRILAAAIEVLSTEDCIRWPSLLAPYQVCIIPPKKGSKEAAAT
                     EIVERLYDDVTEALPQLRGEVLLDDRTHLTIGNRLKDANKLGYPFVIIASKRALEDPA
                     HFEVWSQNTGEVVFLTKEGVMELLTGVHVV"
ORIGIN      
        1 ggcttcgcgt gactgaagag gccggcgctg gtatagagtg ctgctggtgc tggagtgctg
       61 ggattaaagg catatgtcac tatacccgga tgaatttctt taagtgtgat atcttgagct
      121 aatagacatg gaaggatcca catcttggag cccaggctga gaacccagct ataaccatca
      181 tacccacgtg actcattttt ctccatgtac cagggtatca tggaaggttt gctgacaaga
      241 tgcagaacac tgtctgcctt ggctacctgc agcctccgtc actccaggtg catcgtccgc
      301 aagtgttacc actgtgcacc agggagaggg cagcgcttgg tagtatcccg catgttccag
      361 cctcagaacc tccgggaaga ccaggtgctt tctctggagg gcagagctag tgacctgacc
      421 tgtaagagtc agcggctgat gctgcaagtg ggcctgatcc ttccagcgag ccctggctgt
      481 taccacctca tgccctatac agttcgtgcc gtggagaagc ttgtgcgggt gatagaccag
      541 gagatgcagg ccatcggtgg gcagaaaatc aacatgccca gcctcagccc agctgagctg
      601 tggcgggcca ccggccgctg ggacctgatg ggcagggagc tgctgagact gaaagacagg
      661 cacggcaaag agtactgctt gggacccact catgaggaag cagttacagc cctggttgcc
      721 tcccagaaga aactgtccta caagcagctt cccttactgc tgtaccaagt tacaaggaag
      781 tttcgggatg agcctcggcc ccgttttggt ctcctccgtg gccgagagtt ctatatgaag
      841 gacatgtaca cctttgactc ctcctctgag gctgcccagg agacctatag cctggtgtgt
      901 gatgcttatt gtaggctttt cgacaggctg gggttgcgat ggatgaaggc cagggcagat
      961 gtgggcagca ttgggggcac aatgtcccat gaattccagc tgccagtgga cattggagag
     1021 gaccggcttg tggtctgtcc cagctgccac ttctcagcca acacagagat agtagacttg
     1081 tcacaaaaaa tctgccctga ctgccagggt cccctgacag aaaccaaagg catcgaggtg
     1141 gggcacacat tctacctcgg taccaagtac tcttccattt tcaatgccca ctttaccaat
     1201 gcccacgggg aatctttgct ggctgaaatg gggtgctacg gcctgggagt cactcggatc
     1261 ctggctgctg ccatcgaagt tctctctaca gaagactgca tccgctggcc cagcctcctg
     1321 gctccttacc aagtctgcat cataccccct aagaagggta gcaaggaggc agcagccaca
     1381 gagattgtgg agcgattata tgatgacgtc acagaggctc tgcctcagct ccgaggggag
     1441 gttctgctgg atgacaggac ccacctgacc attggaaaca gactaaaaga tgccaacaag
     1501 ctcggctacc cctttgtgat cattgcaagc aagagggccc tggaggaccc tgcgcacttt
     1561 gaggtttggt cccagaacac tggtgaggtg gtcttcctca ccaaagaggg agtcatggaa
     1621 ctgctgactg gcgtgcatgt tgtctaagtg cccaaccaca cctgccccca gacttggtgt
     1681 ccactgtaac actgtagttc cctccacttc cctcccggct ggtttctcca gaaatggctt
     1741 ctcatggatg gtgagagtat gttaggaaaa ccactccttg cttgtgatgg ttcatagtta
     1801 gtcattaact cggccctccc agggctggtt gtgctaccat atgccatatc ttttacaaat
     1861 agacacttct gttaggagga ctgaaaggtg acaaagagac ccaggtcact ttccctccag
     1921 ctgagtttct gggtgtaaga caagaatggt tgaaagctgg ggagatgctt ccccaacccc
     1981 aacccacagt ctgagcacac gccttgcatt tcattcattc cagagagcag ggctagctgc
     2041 ccttctcccc tgagaagccc cgagctgcag agccgagctg cagagagtca agaacctggt
     2101 tgctgctaat tcactggtga tttgacaccc ccacacgccc actggagcct gggattccca
     2161 tctgaacatg gtgatggagt taagtcaata aggtcctagg gctctcactg agcagctcca
     2221 caagacacat gggtctggtt gctcatgcct ctatgcttcc ccagaagcca gatggcccaa
     2281 agctacctcc agatacttga ccgtactggg tcacttcagc actgagatca tgttctgctg
     2341 attgaataaa gtcaagcctt tggggtgaac tttgtgtgcg tgttaacttg aaccaaagat
     2401 aacaccagtt tcagtagtac acacagtaga ctgctctccc cgtctgcctc actggggagg
     2461 ggcagggact gggaaatcct ttaaacagtt tctcccagac ttcaggagca gcacactcca
     2521 gccccacagt gaccttgttg tgggttcaga attgaattcc cgtcgctaca agagcgactg
     2581 gttgagagct gactagattc tgtgggaaac ggagtcatga ctggattcca tagcattgct
     2641 ccagcatcta gatgaggaag atccctcgtc catggaacag tgagtcttgc caccttggtt
     2701 gacactctag atgggctctg agacacctcc agaggtgagc ctcataaatc tagtcgaccc
     2761 taaattcaaa aacttgccaa tgaaggtaaa tcctcataaa aaggtctctg ggctccaaag
     2821 ctggtcctgg gatccttcag ggcttggcag atatatgcac tgggaacctt atggtttgtg
     2881 tgtaagggta gagttactgt agaatcacag cagctggaca gacttagagg agaaagcggg
     2941 ctaagcacct gtattcccct tcatgcttct gccagatgtc aagtgaacag ccacctccag
     3001 ccacatgctc ctgcaaccga gtgcaagtcg gggtgactga actgaaaccc aaatactgct
     3061 tctttgggtc gtttctttgg ggtattttgg tctcagtgac atgagatgtg atctgccttt
     3121 gcaatacatg gagttctgag agcaagctcg ggacaggctg catgacagag gctcttagtt
     3181 tactgcagtt gggatccctg agtcccttac agagttggtt ccagtggggc tgttgccttg
     3241 aaccacacaa attaaagcct ccagaagatt ctggctgcag tcagaaccaa ga
//
