LOCUS       NM_001103351            3179 bp    mRNA    linear   ROD 22-MAR-2023
DEFINITION  Rattus norvegicus poly (ADP-ribose) polymerase family, member 9
            (Parp9), mRNA.
ACCESSION   NM_001103351 XM_001071222 XM_221404
VERSION     NM_001103351.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3179)
  AUTHORS   Yang CS, Jividen K, Spencer A, Dworak N, Ni L, Oostdyk LT,
            Chatterjee M, Kusmider B, Reon B, Parlak M, Gorbunova V, Abbas T,
            Jeffery E, Sherman NE and Paschal BM.
  TITLE     Ubiquitin Modification by the E3 Ligase/ADP-Ribosyltransferase
            Dtx3L/Parp9
  JOURNAL   Mol Cell 66 (4), 503-516 (2017)
   PUBMED   28525742
REFERENCE   2  (bases 1 to 3179)
  AUTHORS   Iwata H, Goettsch C, Sharma A, Ricchiuto P, Goh WW, Halu A, Yamada
            I, Yoshida H, Hara T, Wei M, Inoue N, Fukuda D, Mojcher A, Mattson
            PC, Barabasi AL, Boothby M, Aikawa E, Singh SA and Aikawa M.
  TITLE     PARP9 and PARP14 cross-regulate macrophage activation via STAT1
            ADP-ribosylation
  JOURNAL   Nat Commun 7, 12849 (2016)
   PUBMED   27796300
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 3179)
  AUTHORS   Zhang Y, Mao D, Roswit WT, Jin X, Patel AC, Patel DA, Agapov E,
            Wang Z, Tidwell RM, Atkinson JJ, Huang G, McCarthy R, Yu J, Yun NE,
            Paessler S, Lawson TG, Omattage NS, Brett TJ and Holtzman MJ.
  TITLE     PARP9-DTX3L ubiquitin ligase targets host histone H2BJ and viral 3C
            protease to enhance interferon signaling and control viral
            infection
  JOURNAL   Nat Immunol 16 (12), 1215-1227 (2015)
   PUBMED   26479788
REFERENCE   4  (bases 1 to 3179)
  AUTHORS   Barkauskaite E, Jankevicius G and Ahel I.
  TITLE     Structures and Mechanisms of Enzymes Employed in the Synthesis and
            Degradation of PARP-Dependent Protein ADP-Ribosylation
  JOURNAL   Mol Cell 58 (6), 935-946 (2015)
   PUBMED   26091342
  REMARK    Review article
REFERENCE   5  (bases 1 to 3179)
  AUTHORS   Yan Q, Xu R, Zhu L, Cheng X, Wang Z, Manis J and Shipp MA.
  TITLE     BAL1 and its partner E3 ligase, BBAP, link Poly(ADP-ribose)
            activation, ubiquitylation, and double-strand DNA repair
            independent of ATM, MDC1, and RNF8
  JOURNAL   Mol Cell Biol 33 (4), 845-857 (2013)
   PUBMED   23230272
REFERENCE   6  (bases 1 to 3179)
  AUTHORS   Ghosh D, Lippert D, Krokhin O, Cortens JP and Wilkins JA.
  TITLE     Defining the membrane proteome of NK cells
  JOURNAL   J Mass Spectrom 45 (1), 1-25 (2010)
   PUBMED   19946888
REFERENCE   7  (bases 1 to 3179)
  AUTHORS   Juszczynski P, Kutok JL, Li C, Mitra J, Aguiar RC and Shipp MA.
  TITLE     BAL1 and BBAP are regulated by a gamma interferon-responsive
            bidirectional promoter and are overexpressed in diffuse large
            B-cell lymphomas with a prominent inflammatory infiltrate
  JOURNAL   Mol Cell Biol 26 (14), 5348-5359 (2006)
   PUBMED   16809771
REFERENCE   8  (bases 1 to 3179)
  AUTHORS   Aguiar RC, Takeyama K, He C, Kreinbrink K and Shipp MA.
  TITLE     B-aggressive lymphoma family proteins have unique domains that
            modulate transcription and exhibit poly(ADP-ribose) polymerase
            activity
  JOURNAL   J Biol Chem 280 (40), 33756-33765 (2005)
   PUBMED   16061477
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC128756.1.
            
            On Aug 30, 2012 this sequence version replaced NM_001103351.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC128756.1, SRR8487231.181254.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760400, SAMEA5760494
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-3179              BC128756.1         4-3182
FEATURES             Location/Qualifiers
     source          1..3179
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="11"
                     /map="11q22"
     gene            1..3179
                     /gene="Parp9"
                     /gene_synonym="RGD1307534"
                     /note="poly (ADP-ribose) polymerase family, member 9"
                     /db_xref="GeneID:303905"
                     /db_xref="RGD:1307534"
     exon            1..202
                     /gene="Parp9"
                     /gene_synonym="RGD1307534"
                     /inference="alignment:Splign:2.1.0"
     exon            203..298
                     /gene="Parp9"
                     /gene_synonym="RGD1307534"
                     /inference="alignment:Splign:2.1.0"
     CDS             284..2776
                     /gene="Parp9"
                     /gene_synonym="RGD1307534"
                     /EC_number="2.4.2.30"
                     /note="poly [ADP-ribose] polymerase 9"
                     /codon_start=1
                     /product="protein mono-ADP-ribosyltransferase PARP9"
                     /protein_id="NP_001096821.1"
                     /db_xref="GeneID:303905"
                     /db_xref="RGD:1307534"
                     /translation="MAYYTGTGAAAPTERPADDSLEHYHRWQIPIKHNIFEILKSNES
                     QLYEVLQKKFGCICTLRYPTPAGSSSPAQKVFRRMLTPGIELSVWKDDLTRHVVDAVV
                     NAANEDLLHGGGLAGSLVKIGGSEIQEESKKWIATHGKIPVGGFAVTRAGKLPCYLII
                     HAVGPRWTVMDSQTAIGLLSVAITNILDYVTKWNTCIKTVAIPALSSGIFQFPLHLCT
                     RIIVETICLYFQDKQTVSNLREIHLVSNEGPTVESFKSSSENIFGKEPSSWESLETNP
                     SSNVTLHIGQGLTLQIVQGCIELQTTDVIVNSGHLQDFKSGQVAQSILKRAGFEMEME
                     LDKIKLSSDYQVVQVTKGFKLSCQYVFHVSWHYSISKDQILKNAMKSCLERCLKRDIN
                     SISFPALGTGAINLEKSIAAKIMFEEIVAFAKEHKEKTLTVKIVIFPVDVETYKVFCA
                     EMTKRSSELNLNSDGGLLSLPWTRGEQRSSSLEDGSPAIDLMGVEVGEMCEAKEWIER
                     LLTSKDHHIVENNHILYLGIKEHGMLSQLQTSSNVSISATVSPRTATLEVKGSQADLI
                     EAVMKIECMLCGVQEEVAGKKERSLRSLSGWGTDQQGKLKEMEESCTFQRYPVSLTQE
                     FLDQKKHFDKCGLCVVKVEEVDNEVLLAAFQEKKKMMEEKMPKGSGSQRLFQQVPHQF
                     CNAVCRVGFHRLYSTHNDPVYGAGIYFTKSLKKLADKARKTSSTDRLIYVFEAEVLTG
                     SFCQGNFSNIIPPPLSPGALDVHDSVVDSVSNPETFVIFSGVQAMPRYLWTCTQDRTF
                     SQHPMWSQGYSSEPGMASSLQSWGRVSNGSPV"
     exon            299..332
                     /gene="Parp9"
                     /gene_synonym="RGD1307534"
                     /inference="alignment:Splign:2.1.0"
     exon            333..1186
                     /gene="Parp9"
                     /gene_synonym="RGD1307534"
                     /inference="alignment:Splign:2.1.0"
     exon            1187..1402
                     /gene="Parp9"
                     /gene_synonym="RGD1307534"
                     /inference="alignment:Splign:2.1.0"
     exon            1403..1621
                     /gene="Parp9"
                     /gene_synonym="RGD1307534"
                     /inference="alignment:Splign:2.1.0"
     exon            1622..1679
                     /gene="Parp9"
                     /gene_synonym="RGD1307534"
                     /inference="alignment:Splign:2.1.0"
     exon            1680..2069
                     /gene="Parp9"
                     /gene_synonym="RGD1307534"
                     /inference="alignment:Splign:2.1.0"
     exon            2070..2206
                     /gene="Parp9"
                     /gene_synonym="RGD1307534"
                     /inference="alignment:Splign:2.1.0"
     exon            2207..2381
                     /gene="Parp9"
                     /gene_synonym="RGD1307534"
                     /inference="alignment:Splign:2.1.0"
     exon            2382..3152
                     /gene="Parp9"
                     /gene_synonym="RGD1307534"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ggttcaagca gtttcttctg tcttccgaga cgctgtgggg gagcaccact gttgagaagg
       61 ccgttctttc gacgtttttc ctggtctcag cactttccta tcctaagtct accaacacca
      121 tcaagacctc acttccacag agcgtttcct gttccagccc ctacaggttt ccccctctga
      181 cttcaaccac cattaccaga agggcaccat ctcctggatt acagagtaca cttggaaaca
      241 caaacgagta taaacatccg gagacccgcg tgggacgtga agaatggcct attacacggg
      301 tacaggagca gcagctccca ccgaaagacc agccgatgat tctcttgaac actaccatag
      361 atggcaaatt cccattaaac acaacatctt cgaaattttg aaaagcaatg agagtcagtt
      421 gtatgaagtc ctccagaaaa agtttggatg tatctgtacc ctgagatatc caactccagc
      481 aggaagcagc tctcctgctc agaaggtctt cagaaggatg ctgacccctg ggatagagct
      541 atctgtctgg aaggatgacc tcaccagaca tgttgttgat gctgtggtga acgcagccaa
      601 tgaagacctt ttgcatggag gtggcctggc tggaagcttg gtgaaaattg gtggctctga
      661 aatccaagaa gagagcaaaa aatggattgc cacccatggt aaaattccag tcggtggatt
      721 tgctgtcacc agagcgggga agcttccttg ctatttgatt atccatgcag ttggacctcg
      781 gtggaccgtt atggacagcc agacagctat tggattactg tcagtcgcca ttaccaacat
      841 tctagactat gtcaccaaat ggaatacatg cattaagaca gtagcaattc cagccctgag
      901 ctctggaatt ttccagttcc ctctgcattt gtgtacacgc ataattgtag aaactatctg
      961 tctttatttc caagacaagc aaacagtcag taatttgcga gagattcatc tggtgagcaa
     1021 tgagggcccc actgttgagt cctttaaatc ctcctcagaa aacatcttcg ggaaggagcc
     1081 gagctcctgg gagagcctag aaactaaccc ttcttccaac gtaactcttc acattggcca
     1141 gggcctgact cttcagattg tccaaggctg cattgagctg caaacaacag atgtaattgt
     1201 taattctgga cacctgcagg attttaaatc gggacaagtg gcacaatcga ttcttaaaag
     1261 agcagggttt gaaatggaaa tggaacttga caagattaaa ctgtcctcag attatcaagt
     1321 ggtacaggtc acaaaaggat ttaaattgtc ctgtcagtac gtgttccacg tgtcatggca
     1381 ttacagtatc agcaaggacc agatattgaa aaatgcaatg aagtcctgtc tagaaagatg
     1441 ccttaaacga gatataaatt ccatttcctt tcctgctctc gggacaggag caattaattt
     1501 agagaagagt atagcagcta agataatgtt tgaggaaatt gttgcatttg ctaaagagca
     1561 caaggagaaa acgttaactg tgaagattgt gatctttcca gtagatgtgg agacatacaa
     1621 ggttttttgt gctgaaatga cgaaaaggtc cagtgagctg aatctcaaca gtgatggagg
     1681 ccttttatcc ctgccgtgga ccagagggga gcaaagaagc agcagccttg aggatggatc
     1741 tcctgccatc gatctcatgg gtgtagaagt gggagagatg tgtgaggcca aggaatggat
     1801 tgaaaggttg ctgacctcca aggaccatca catcgttgag aataatcata ttctctacct
     1861 tgggataaaa gagcacggca tgttgtctca gctccagaca agttcaaacg tctccatttc
     1921 agcgacagtc agtcctagaa cggcaacttt agaggttaaa ggttcccagg ccgacctcat
     1981 tgaagcagtt atgaagattg aatgtatgct gtgtggagtt caggaagaag tggcaggaaa
     2041 aaaggaaaga agtcttcgga gcttgtcagg atggggaact gaccagcaag gaaaactgaa
     2101 agaaatggaa gaatcgtgca catttcaacg atacccagta tctttaactc aggaatttct
     2161 ggaccaaaag aaacactttg acaagtgtgg cttgtgtgtt gtgaaggtgg aggaggtaga
     2221 caatgaggtg ttgctggctg cgttccaaga gaagaagaag atgatggaag agaagatgcc
     2281 aaagggatct gggagccaaa ggttgtttca gcaggtccca caccagttct gcaatgcagt
     2341 atgcagagtc ggcttccaca gactgtactc cacacacaat gacccagttt atggagccgg
     2401 catatatttc accaagagcc tcaaaaaact agcagacaag gccaggaaaa cctctagcac
     2461 agacaggcta atctatgtgt ttgaggcaga agtactcaca gggtccttct gtcagggtaa
     2521 tttctcaaat atcatccctc cgccattgag tcctggggct ttagatgttc atgacagcgt
     2581 ggttgacagt gtttccaacc ctgaaacctt tgttattttt agtggcgtac aggcgatgcc
     2641 caggtacttg tggacttgta cacaggatag gacattctca cagcatccaa tgtggtccca
     2701 gggctactcg tcagaaccag gaatggcctc ttcgctgcag tcctggggaa gggtctcaaa
     2761 tggcagccct gtttagtctc cacgtcattt taacaagcag aagggtttgc gtgaactgac
     2821 aaaaatgacg accattagtg acttgagtaa caggttatct gttcagattg atggggtcac
     2881 taaaggcacc agccacacac tagcatctag tgccttcacc agtagctggg cagatgccag
     2941 ctaaaacttc ctcactgtct tttctacttg acatctttta tctccttccc tgtaggtgac
     3001 agcaagaata ctttatatag aacaaggatt cttttttcaa gtctgttatt ctaaaatgtg
     3061 atagcacaaa ctaggacgac aggatgattt tgatttttct atataatttt ataaagtgct
     3121 ttggatattc aaataaatca cctttgtctg aaaaaaaaaa aaaaaaaaaa aaaaaaaaa
//
