LOCUS       XM_039103518            3444 bp    mRNA    linear   ROD 11-JUN-2023
DEFINITION  PREDICTED: Rattus norvegicus poly (ADP-ribose) polymerase family,
            member 8 (Parp8), transcript variant X1, mRNA.
ACCESSION   XM_039103518
VERSION     XM_039103518.1
DBLINK      BioProject: PRJNA677964
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_051337.1) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            [WARNING] On Jan 9, 2024 this sequence was replaced by
            NM_001427069.1.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_015227675.2-RS_2023_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/06/2023
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3444
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN/NHsdMcwi"
                     /db_xref="taxon:10116"
                     /chromosome="2"
                     /sex="male"
                     /tissue_type="kidney"
                     /geo_loc_name="USA: Wisconsin, Milwaukee, Medical College
                     of Wisconsin"
                     /collection_date="2019-03-08"
                     /collected_by="Rebecca Schilling"
     gene            1..3444
                     /gene="Parp8"
                     /note="poly (ADP-ribose) polymerase family, member 8;
                     Derived by automated computational analysis using gene
                     prediction method: Gnomon. Supporting evidence includes
                     similarity to: 19 ESTs, 15 Proteins, and 100% coverage of
                     the annotated genomic feature by RNAseq alignments,
                     including 107 samples with support for all annotated
                     introns"
                     /db_xref="GeneID:294762"
                     /db_xref="RGD:1587384"
     CDS             486..3170
                     /gene="Parp8"
                     /codon_start=1
                     /product="protein mono-ADP-ribosyltransferase PARP8
                     isoform X1"
                     /protein_id="XP_038959446.1"
                     /db_xref="GeneID:294762"
                     /db_xref="RGD:1587384"
                     /translation="MQSRPPPPPPPPPPPPPPPLSPGITSETTSPSAPASARGIYLMG
                     MCSRQERIQKDIDVVIQKSRAEKDCLFADFRYSDSTFTFTYVGGPKSVSYSVHVSEDY
                     PDNTYVSSSENDEDVLVTTDPIPVIFHRIATELRKTNDINCCLSIRSKLQKENGEESR
                     QNSTVEEDSEGDNDSEEFYYGGQVNYDGELHKHPQLEADLSAVRELYGPHAVSLREYG
                     AIDDVDIDLHIDVSFLDEEIAVAWEVIRTEPIIVRLHCSLTQYLNGPVPTVDVFQIST
                     KERFGLGHQLKKIMQTFVSQQWKQSKEKSNCPHGKKLSEKKVKSPLHLFSTLRRSPSY
                     PPPGCGKSKSKLKPEQDGISKTHKLLRRTCSSTVKADDMCAKSHRTFGRSLSSDPRAE
                     QAMSTIKSHKLLGRPCSAASKQEDCLTLKSHKLLTRSCSGDPRCEHNTNLKPHKLLSR
                     SYSSNLRMEELYGLKNHKLLSKSYSSAPKSSKTEHFKEPNAEGRRLSLTSGLIGILTP
                     SSSSSQPPTNGAKCIPIRDRGFLVQTIEFAEQRIPVLNEYCVVCDEPHVFQNGPMLRP
                     TVCERELCVFAFQTLGVMNEAADEIATGAQVVDLLVSMCRSALESPRKVVIFEPYPSV
                     VDPNDPQMLAFNPRKKNYDRVMKALDSITSIREMTQAPYLEIKKQMDKQDPLAHPLLQ
                     WVISSNRSHIVKLPVNRQLKFMHTPHQFLLLSSPPAKESNFRAAKKLFGSTFAFHGSH
                     IENWHSILRNGLVVASNTRLQLHGAMYGSGIYLSPMSSISFGYSGMNKKQKVSTKDEP
                     ASSSKSSNASQSQKKGQQSQFLQSRNLKCIALCEVITSPDLHKHGEIWVVPNTDHVCT
                     RFFFVYEDGQVGDANINTQEGGIHKEILRVIGNQTATG"
ORIGIN      
        1 agggagtctt cactacctac actgtcactc agctcccggc gcgagtggca gtcgggggtg
       61 gggaaatcca gcctgcgcgg atggcggata ctattaaagc cccagcggcg cgcagccggg
      121 cccggtgacc cgcggcgggt gcgggagggt ctgcggctgg cgggcggcgc tgcagcagcc
      181 tgggcacggc cgccgcccgc gggcgcgagt gtgcgcgggt gtgggaaggc cggcgtgcgg
      241 gccgcgaggg gtgtgcgcgc gtgagtcgga gcggggctcg cccctcgccg gcgcctgccg
      301 ctccacggct gccgatcgct ctccagcggt ccccggcccc cttcgggccc ctcggttccc
      361 tacggccgtc agtccgggcg ggggagggag aaagtgagac tcggtgtcat caccatccat
      421 tgtcagaacg ggaggaaatt ggaatccagc agcggcgagc agcagctggg cggtcacatc
      481 tgggaatgca aagccgacct cccccccctc ctcctcctcc tcctccacct cctcctcctc
      541 ctctctcacc cgggatcact tccgaaacca cttcgccttc agcccctgcc tcggccagag
      601 ggatttattt aatggggatg tgttcaaggc aagagagaat tcagaaggat atcgacgtcg
      661 tgatccagaa gtccagagca gagaaagact gcctgtttgc agatttcaga tactcagact
      721 ccacctttac tttcacctac gttggcggcc ccaaaagtgt atcctactca gtacacgttt
      781 cagaagacta tccagacaat acatatgtgt caagttcaga aaatgatgag gatgtcctag
      841 tcaccacgga cccgattcct gtcattttcc atagaattgc aacagaatta agaaaaacaa
      901 atgatattaa ctgctgtttg tccataagat ctaaattaca aaaggaaaat ggggaggagt
      961 caaggcagaa tagtacagtg gaagaagact cggagggtga caacgactct gaagagtttt
     1021 attatggagg acaggtgaac tatgacgggg aactgcacaa gcaccctcag ttagaagctg
     1081 atctgtctgc agtgagagag ctctatggac cacatgcagt ttctctcagg gaatatggag
     1141 ctatcgatga tgtagatatt gatctgcaca tagatgtcag cttcctggat gaggaaattg
     1201 ctgtggcctg ggaagtgatt cgaacagaac ctattattgt ccgactacac tgttctctta
     1261 cacagtacct aaatggccca gtgcccacgg ttgatgtctt tcagatttca acaaaagagc
     1321 ggtttggatt gggacatcag ctgaaaaaaa tcatgcagac atttgtttct cagcagtgga
     1381 aacagagcaa agaaaagtcc aattgcccgc acggtaagaa gctgtcggag aagaaggtga
     1441 agtctcctct acatttgttt tctaccctgc gcaggtcgcc cagctatcct ccccctggat
     1501 gtggcaaaag caaatccaaa ctgaaacccg aacaagacgg catctccaaa actcataagc
     1561 tgctgcggag gacttgctcc agtaccgtca aagctgacga tatgtgtgcc aagtcgcaca
     1621 ggacttttgg gcgctcgctg tccagtgatc ccagggccga gcaggcgatg tccaccatta
     1681 aatcgcacaa acttttgggc cggccctgtt ccgcagccag caagcaggag gactgcctca
     1741 cactaaagtc ccataagtta ttgactcgat cttgttctgg agacccacga tgtgagcaca
     1801 acaccaactt gaagccccac aaactgctaa gcaggtctta ctctagtaat ctcagaatgg
     1861 aagagttata tgggctgaaa aaccacaaat tgctcagcaa gtcttactcc agtgccccca
     1921 agtcatcgaa aacagagcat ttcaaggaac ccaacgcaga gggcaggagg ctctcgctta
     1981 cctcagggct tatcggtatt ttaacaccat catcgtcttc ttcccagcct cctacaaatg
     2041 gtgcaaaatg cattccaatc cgagaccgcg gcttcctggt gcagaccatt gagtttgctg
     2101 agcagcggat ccctgtactg aatgaatact gtgtggtgtg tgatgaacca cacgtgtttc
     2161 aaaatggccc catgcttagg cccacagtgt gtgagcgaga gctgtgtgta tttgcttttc
     2221 aaaccctggg agtgatgaat gaagctgccg atgagatagc taccggagct caggtggtag
     2281 acctcctcgt gtccatgtgt agatctgcgc tggaatctcc tagaaaagtt gtcatttttg
     2341 agccatatcc ttctgtggta gatcctaatg accctcagat gttagccttc aaccccagga
     2401 agaagaacta tgatcgagta atgaaagctc tggacagcat aacttccatc agagaaatga
     2461 cacaggcacc ttatctggaa atcaagaagc agatggataa acaggacccc cttgctcatc
     2521 cacttctgca atgggtcatc tccagtaata ggtcacatat tgtgaaactg ccagtcaaca
     2581 ggcaactgaa gttcatgcac actccacacc agttcctcct cctcagcagc ccaccagcca
     2641 aagagtccaa cttcagagct gccaagaagc tctttggaag caccttcgcc tttcatggct
     2701 ctcacattga aaactggcac tctatcctga ggaatggtct ggtcgttgcc tctaacacac
     2761 gtctgcagct ccacggtgcg atgtacggaa gtgggatcta tcttagccca atgtcgagca
     2821 tatcgtttgg ttactcaggg atgaacaaga agcagaaggt atcaaccaag gacgagccag
     2881 cttcgagtag taaaagcagc aatgcgtcac agtctcagaa aaaaggacag caatcccagt
     2941 tcctgcaaag ccgtaacttg aaatgcatag ccttatgtga agtgatcacg tcacctgacc
     3001 tgcacaaaca tggcgagata tgggttgtcc cgaacacgga tcatgtctgt acacgattct
     3061 tttttgtcta tgaagatggc caggtgggcg atgccaatat caacacacaa gaaggaggta
     3121 ttcacaaaga gatactccga gtgattggga atcagactgc aactggttaa aggaccacca
     3181 catcacagga tttgaaagcc ttcctcgggt tcaaagctgg attttgaact gaagaagatg
     3241 acaaaataat ttattgttat tataaacaaa attaaccctt tgaatactga tttttctttt
     3301 cttagtattt ctaaatattt cattaaatgc ctaaaatggt ataagattta ccaattgtag
     3361 ggtaatggaa tccagtaaat aaaaattgaa cagcacttaa accgaatttc gggttgcata
     3421 cacaataaac agattgaaaa aaca
//
