LOCUS       NM_001106828            2610 bp    mRNA    linear   ROD 22-MAR-2023
DEFINITION  Rattus norvegicus poly (ADP-ribose) polymerase family, member 6
            (Parp6), mRNA.
ACCESSION   NM_001106828 XM_001073042 XM_217149
VERSION     NM_001106828.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2610)
  AUTHORS   Huang JY, Wang K, Vermehren-Schmaedick A, Adelman JP and Cohen MS.
  TITLE     PARP6 is a Regulator of Hippocampal Dendritic Morphogenesis
  JOURNAL   Sci Rep 6, 18512 (2016)
   PUBMED   26725726
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2610)
  AUTHORS   Barkauskaite E, Jankevicius G and Ahel I.
  TITLE     Structures and Mechanisms of Enzymes Employed in the Synthesis and
            Degradation of PARP-Dependent Protein ADP-Ribosylation
  JOURNAL   Mol Cell 58 (6), 935-946 (2015)
   PUBMED   26091342
  REMARK    Review article
REFERENCE   3  (bases 1 to 2610)
  AUTHORS   Vyas S, Matic I, Uchima L, Rood J, Zaja R, Hay RT, Ahel I and Chang
            P.
  TITLE     Family-wide analysis of poly(ADP-ribose) polymerase activity
  JOURNAL   Nat Commun 5, 4426 (2014)
   PUBMED   25043379
  REMARK    Publication Status: Online-Only
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473975.1.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_001073042.1, XM_217149.4.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMD00132261,
                              SAMD00132263 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..2610
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="8"
                     /map="8q24"
     gene            1..2610
                     /gene="Parp6"
                     /gene_synonym="RGD1310937"
                     /note="poly (ADP-ribose) polymerase family, member 6"
                     /db_xref="GeneID:300759"
                     /db_xref="RGD:1310937"
     exon            1..50
                     /gene="Parp6"
                     /gene_synonym="RGD1310937"
                     /inference="alignment:Splign:2.1.0"
     exon            51..291
                     /gene="Parp6"
                     /gene_synonym="RGD1310937"
                     /inference="alignment:Splign:2.1.0"
     exon            292..486
                     /gene="Parp6"
                     /gene_synonym="RGD1310937"
                     /inference="alignment:Splign:2.1.0"
     CDS             484..2376
                     /gene="Parp6"
                     /gene_synonym="RGD1310937"
                     /EC_number="2.4.2.30"
                     /note="poly [ADP-ribose] polymerase 6"
                     /codon_start=1
                     /product="protein mono-ADP-ribosyltransferase PARP6"
                     /protein_id="NP_001100298.1"
                     /db_xref="GeneID:300759"
                     /db_xref="RGD:1310937"
                     /translation="MDIKGQFWNDDDSEGDNESEEFLYGVQGSCAADLYRHPQLDADI
                     EAVKEIYSENSVSIREYGTIDDVDIDLHINISFLDEEVSTAWKVLRTEPIVLRLRFSL
                     SQYLDGPEPSIEVFQPSNKEGFGLGLQLKKILYMFTSQQWKHLSNDLLKTQQEKRHSW
                     FKASGSIRKFRAGLSIFSPIPKSPSFPIIQDSMLKGKLGVPELRVGRLMNRSISCTMK
                     NPKVEVFGYPPSPQAGLLCPQHVGLPPPARTSPLVSGHCKNIPTLEYGFLVQIMKYAE
                     QRVPTLNEYCVVCDEQHVFQNGSMLKPAVCTRELCVFSFYTLGVMSGAAEEVATGAEV
                     VDLLVAMCRAALESPRKSIIFEPYPSVVDPTDPKTLAFNPKKKNYERLQKALDSVMSI
                     REMTQGSYLEIKKQMDKLDPLAHPLLQWIISSNRSHIVKLPLSRLKFMHTSHQFLLLS
                     SPPAKEARFRTAKKLYGSTFAFHGSHIENWHSILRNGLVNASYTKLQLHGAAYGKGIY
                     LSPISSISFGYSGMGKGQHRMPSKDELVQRYNRMNTIPQTRSIQSRFLQSRNLNCIAL
                     CEVITSKDLQKHGNIWVCPVSDHVCTRFFFVYEDGQVGDANINTQDPKIQKEIMRVIG
                     TQVYTN"
     exon            487..564
                     /gene="Parp6"
                     /gene_synonym="RGD1310937"
                     /inference="alignment:Splign:2.1.0"
     exon            565..659
                     /gene="Parp6"
                     /gene_synonym="RGD1310937"
                     /inference="alignment:Splign:2.1.0"
     exon            660..720
                     /gene="Parp6"
                     /gene_synonym="RGD1310937"
                     /inference="alignment:Splign:2.1.0"
     exon            721..811
                     /gene="Parp6"
                     /gene_synonym="RGD1310937"
                     /inference="alignment:Splign:2.1.0"
     exon            812..878
                     /gene="Parp6"
                     /gene_synonym="RGD1310937"
                     /inference="alignment:Splign:2.1.0"
     exon            879..1028
                     /gene="Parp6"
                     /gene_synonym="RGD1310937"
                     /inference="alignment:Splign:2.1.0"
     exon            1029..1239
                     /gene="Parp6"
                     /gene_synonym="RGD1310937"
                     /inference="alignment:Splign:2.1.0"
     exon            1240..1293
                     /gene="Parp6"
                     /gene_synonym="RGD1310937"
                     /inference="alignment:Splign:2.1.0"
     exon            1294..1389
                     /gene="Parp6"
                     /gene_synonym="RGD1310937"
                     /inference="alignment:Splign:2.1.0"
     exon            1390..1482
                     /gene="Parp6"
                     /gene_synonym="RGD1310937"
                     /inference="alignment:Splign:2.1.0"
     exon            1483..1608
                     /gene="Parp6"
                     /gene_synonym="RGD1310937"
                     /inference="alignment:Splign:2.1.0"
     exon            1609..1674
                     /gene="Parp6"
                     /gene_synonym="RGD1310937"
                     /inference="alignment:Splign:2.1.0"
     exon            1675..1742
                     /gene="Parp6"
                     /gene_synonym="RGD1310937"
                     /inference="alignment:Splign:2.1.0"
     exon            1743..1791
                     /gene="Parp6"
                     /gene_synonym="RGD1310937"
                     /inference="alignment:Splign:2.1.0"
     exon            1792..1901
                     /gene="Parp6"
                     /gene_synonym="RGD1310937"
                     /inference="alignment:Splign:2.1.0"
     exon            1902..1974
                     /gene="Parp6"
                     /gene_synonym="RGD1310937"
                     /inference="alignment:Splign:2.1.0"
     exon            1975..2044
                     /gene="Parp6"
                     /gene_synonym="RGD1310937"
                     /inference="alignment:Splign:2.1.0"
     exon            2045..2124
                     /gene="Parp6"
                     /gene_synonym="RGD1310937"
                     /inference="alignment:Splign:2.1.0"
     exon            2125..2188
                     /gene="Parp6"
                     /gene_synonym="RGD1310937"
                     /inference="alignment:Splign:2.1.0"
     exon            2189..2273
                     /gene="Parp6"
                     /gene_synonym="RGD1310937"
                     /inference="alignment:Splign:2.1.0"
     exon            2274..2610
                     /gene="Parp6"
                     /gene_synonym="RGD1310937"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cccgggccgc tcgtcccctc cgcggcggcc gcgcgcggcc cggggtcgcc cagcagaaag
       61 caaacagcaa accctgaaga gatgctcagt ttttcttgac ttctacagtg aaagaccttg
      121 aaaaagttgg cacttctagc ctaagcggcc ctcattctac tgctcacccc aagacaaccc
      181 aggctggact gtagcgcttc cctcatcaac cagagcagca tttgactgtt ttcaaatcta
      241 aaagaaccct ggccccaaac ttcataattg gcacctcagc tgctctttaa ggacagtgac
      301 ttattaccac cacaacagag cctgccatcc ccagcagatt gccagcacct atgacatcat
      361 ccccttcttt gtctcattct gtggtctgct aaatgctcat ctcgttggct tggatttagt
      421 tggtggtatg gaggggtgct gcttagcact gacctgagag tgtgtgtgaa acccactgac
      481 ccaatggaca tcaaaggcca gttctggaat gatgatgatt cagaaggaga taatgaatca
      541 gaggagtttc tgtatggagt tcaggggagc tgtgcagctg acctttatag acacccacag
      601 cttgatgcag acattgaagc agtgaaggag atctacagcg agaactccgt gtccatcaga
      661 gaatatggaa ctatcgatga tgtggacatt gacctccaca ttaacatcag cttcctcgat
      721 gaagaagtat ctacagcttg gaaggtcctc cgaacagaac ctattgtgtt gaggctacgg
      781 ttttctctct cccagtacct tgatggacca gaaccatcaa tcgaggtttt ccagccatcg
      841 aataaggaag ggtttgggct aggtcttcag ttgaaaaaaa tcctgtatat gtttacatcc
      901 caacaatgga agcatctgag caacgatctc ctgaagaccc agcaggagaa gagacacagt
      961 tggttcaagg cgagtggtag catcaggaag ttccgagctg gcctcagcat cttctcaccc
     1021 attcccaagt ctcccagttt tcctatcata caggactcca tgctgaaggg caaactgggt
     1081 gtaccagagc ttcgagttgg acgccttatg aatcgttcca tttcttgcac catgaagaac
     1141 ccaaaagtag aggtgtttgg ctatcccccc agcccccagg caggtctcct gtgcccccag
     1201 cacgtgggcc tccctccccc agcacggact tctcctttgg tcagtggtca ctgcaagaac
     1261 atccccactc tggagtatgg attccttgta cagattatga agtatgcaga gcagagggtt
     1321 ccgacgttga atgagtactg tgtggtgtgt gatgagcagc acgtcttcca gaatgggtcc
     1381 atgctcaagc cagctgtctg tactcgggag ttatgtgtct tctccttcta cacactggga
     1441 gtcatgtctg gagctgcaga agaagtggct acaggagcag aggtggtaga tctgctggtg
     1501 gccatgtgta gagcagcttt ggagtcccct agaaaaagca tcatcttcga gccttatccc
     1561 tctgtggtgg accccactga tcccaagact ctggccttta accctaagaa gaagaattat
     1621 gagcggcttc agaaagctct ggatagtgtg atgtctattc gggagatgac ccagggctca
     1681 tatttggaaa tcaagaaaca gatggacaag ctggatccct tggcccatcc tcttctgcag
     1741 tggataattt ctagcaacag gtcacacatt gtcaaactac ctctcagcag gctgaagttc
     1801 atgcacacct cacaccaatt cctcctgctg agcagccctc ctgccaagga ggctcggttc
     1861 cggaccgcca agaagctcta cggaagcacc tttgccttcc atgggtccca cattgagaat
     1921 tggcattcaa tcctgcgcaa tgggctggtc aatgcatcct acactaaact gcagctgcat
     1981 ggagcagcct atggcaaagg catctacctg agccccatct ccagtatttc ctttggatac
     2041 tcaggaatgg gcaaaggaca gcacaggatg ccttccaagg acgagctggt ccagagatac
     2101 aacaggatga acaccatccc ccagacccga tccattcagt caaggttcct gcagagtcgg
     2161 aatctaaact gtatagcact ctgtgaagtg attacatcta aggacctcca gaagcatgga
     2221 aacatttggg tgtgccctgt gtctgaccat gtctgcacaa ggttcttctt tgtatatgag
     2281 gatgggcaag tgggcgatgc caacattaat actcaggacc ccaagataca gaaggaaatc
     2341 atgcgtgtga ttggaactca ggtttacaca aactgagggg gccccagccc tcgtaccacc
     2401 ctgttcccca ggatccatct gcccttgtca aagggctcag gagcagcaag tgaggctgcc
     2461 ctgagaaatc caaggggcaa gaaaagaaga ggcggccttc atggtggaga ttgatccagg
     2521 aactactcca catttggatg gccctgactg actcccaccc ctgattgtaa ataaaacaat
     2581 aaaatggaag gtgctgtgga ctggatatga
//
