LOCUS       NP_001099845             614 aa            linear   ROD 24-JUN-2024
DEFINITION  bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 2
            [Rattus norvegicus].
ACCESSION   NP_001099845 XP_001079800 XP_215288
VERSION     NP_001099845.2
DBSOURCE    REFSEQ: accession NM_001106375.2
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (residues 1 to 614)
  AUTHORS   Kurima,K., Singh,B. and Schwartz,N.B.
  TITLE     Genomic organization of the mouse and human genes encoding the ATP
            sulfurylase/adenosine 5'-phosphosulfate kinase isoform SK2
  JOURNAL   J Biol Chem 274 (47), 33306-33312 (1999)
   PUBMED   10559207
REFERENCE   2  (residues 1 to 614)
  AUTHORS   Rusiniak,M.E., O'Brien,E.P., Novak,E.K., Barone,S.M., McGarry,M.P.,
            Reddington,M. and Swank,R.T.
  TITLE     Molecular markers near the mouse brachymorphic (bm) gene, which
            affects connective tissues and bleeding time
  JOURNAL   Mamm Genome 7 (2), 98-102 (1996)
   PUBMED   8835524
REFERENCE   3  (residues 1 to 614)
  AUTHORS   Johnson,D.R.
  TITLE     The growth of femur and tibia in three genetically distinct
            chondrodystrophic mutants of the house mouse
  JOURNAL   J Anat 125 (Pt 2), 267-275 (1978)
   PUBMED   624676
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC169061.1.
            
            On Sep 14, 2008 this sequence version replaced NP_001099845.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC169061.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5756307, SAMEA5760384
                                           [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..614
                     /organism="Rattus norvegicus"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q52"
     Protein         1..614
                     /product="bifunctional 3'-phosphoadenosine
                     5'-phosphosulfate synthase 2"
                     /calculated_mol_wt=69281
     Region          22..216
                     /region_name="CysC"
                     /note="Adenylylsulfate kinase or related kinase [Inorganic
                     ion transport and metabolism]; COG0529"
                     /db_xref="CDD:440295"
     Region          243..606
                     /region_name="ATPS"
                     /note="ATP-sulfurylase; cd00517"
                     /db_xref="CDD:173895"
     Site            order(407..411,417,420,484,509..511,513..514,550..552)
                     /site_type="active"
                     /db_xref="CDD:173895"
     Site            414..417
                     /site_type="other"
                     /note="HXXH motif"
                     /db_xref="CDD:173895"
     Site            445..455
                     /site_type="other"
                     /note="flexible loop"
                     /db_xref="CDD:173895"
     CDS             1..614
                     /gene="Papss2"
                     /coded_by="NM_001106375.2:36..1880"
                     /db_xref="GeneID:294103"
                     /db_xref="RGD:1307012"
ORIGIN      
        1 mseikkqktd qqkstnvvyq ahhvsrnkrg qvvgtrggfr gctvwltgls gagkttisfa
       61 leeylvshai pcysldgdnv rhglnknlgf sagdreenir riaevaklfa daglvcitsf
      121 ispfakdren arkihesagl pffeifvdap lnicesrdvk glykrarage ikgftgidsn
      181 yekpetpecv lktnlssvsd cvqqvvellq eqsivphtti kgihelfvpe nkidqirael
      241 etlpslpitk ldlqwvqils egwatplkgf mrekeylqtl hfdtllddgv inmsipivlp
      301 vsgddkarle gcskfalmye grrvallqdp efyehrkeer csrvwgtasa khphikmvme
      361 ggdwlvggdl qvlerirwnd gldqyrltpl elkqkckdmd adavfafqlr npvhnghall
      421 mqdtrrrlle rgykhpvlll hplggwtkdd dvpldwrmkq haavleegil dpkstivaif
      481 pspmlyagpt evqwhcrcrm iaganfyivg rdpagmphpe tkkdlyepth ggkvlsmapg
      541 ltsveiipfr vaaynkikka mdfydparhd efdfisgtrm rklaregedp pdgfmapkaw
      601 kvltdyyrsl ekin
//
