LOCUS       XM_006240521            4685 bp    mRNA    linear   ROD 11-JUN-2023
DEFINITION  PREDICTED: Rattus norvegicus poly (A) polymerase alpha (Papola),
            transcript variant X2, mRNA.
ACCESSION   XM_006240521
VERSION     XM_006240521.4
DBLINK      BioProject: PRJNA677964
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_051341.1) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            [WARNING] On Feb 22, 2024 this sequence was replaced by
            XM_006240521.5.
            
            On Jan 21, 2021 this sequence version replaced XM_006240521.3.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_015227675.2-RS_2023_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/06/2023
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4685
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN/NHsdMcwi"
                     /db_xref="taxon:10116"
                     /chromosome="6"
                     /sex="male"
                     /tissue_type="kidney"
                     /geo_loc_name="USA: Wisconsin, Milwaukee, Medical College
                     of Wisconsin"
                     /collection_date="2019-03-08"
                     /collected_by="Rebecca Schilling"
     gene            1..4685
                     /gene="Papola"
                     /note="poly (A) polymerase alpha; Derived by automated
                     computational analysis using gene prediction method:
                     Gnomon. Supporting evidence includes similarity to: 29
                     ESTs, 43 long SRA reads, 9 Proteins, and 100% coverage of
                     the annotated genomic feature by RNAseq alignments,
                     including 95 samples with support for all annotated
                     introns"
                     /db_xref="GeneID:314417"
                     /db_xref="RGD:1308673"
     CDS             296..2572
                     /gene="Papola"
                     /codon_start=1
                     /product="poly(A) polymerase alpha isoform X2"
                     /protein_id="XP_006240583.1"
                     /db_xref="GeneID:314417"
                     /db_xref="RGD:1308673"
                     /translation="MPFPVTTQGSQQTQPPQRHYGITSPISLAAPKETDCLLTQKLIE
                     TLKPFGVFEEEEELQRRILILGKLNNLVKEWIREISESKNLPQSVIENVGGKIFTFGS
                     YRLGVHTKGADIDALCVAPRHVDRSDFFTSFYDKLKLQEEVKDLRAVEEAFVPVIKLC
                     FDGIEIDILFARLALQTIPEDLDLRDDSLLKNLDIRCIRSLNGCRVTDEILHLVPNID
                     NFRLTLRAIKLWAKRHNIYSNILGFLGGVSWAMLVARTCQLYPNAIASTLVHKFFLVF
                     SKWEWPNPVLLKQPEECNLNLPVWDPRVNPSDRYHLMPIITPAYPQQNSTYNVSVSTR
                     MVMVEEFKQGLAITDEILLSKAEWSKLFEAPNFFQKYKHYIVLLASAPTEKQRLEWVG
                     LVESKIRILVGSLEKNEFITLAHVNPQSFPAPKESPDREEFRTMWVIGLVFKKTENSE
                     NLSVDLTYDIQSFTDTVYRQAINSKMFELDMKIAAMHVKRKQLHQLLPSHVLQKRKKH
                     STEGVKLAALNDSSLDLSMDSDNSMSVPSPTSAMKTSPLNSSGSSQGRNSPAPAVTAA
                     SVTSIQASEVSVPQANSSESPGGPSSESIPQTATQPAISPPPKPTVSRVVSSTRLVNP
                     SPRPSGNAATKVPNPIVGVKRTSSPHKEESPKKTKTEEDETSEDANCLALSGHDKTET
                     KEQVGMETSAAPSEAAPASASLVASQEEAVGDASPVSDSALNRAVFFAFVLRKHPVQT
                     FPISLLSLQTLFLLSRIQ"
ORIGIN      
        1 ttcaagaact acatttcccg tcgggccttg tggtgccgtg cagagagtgc gcaggcgtgc
       61 gctcggtgtg cgtggcggcg tcagcgattc tagaacgttg ctgtggtagc gctcgggcgc
      121 catgttagga cgaaggggaa ggaggagaag cgcttaaagc ggcggggcgc gggtgcagga
      181 ctgggttggc cctggggctg aggcaggccg ccgtccctcc cgcctcggtg gatcatgccc
      241 agggcggcag cggtcgcggg ggggaagtga ctgggcggtg ccggcgccgg agacgatgcc
      301 gtttccagtt acaacgcagg gatcacaaca aacgcagccg ccacagaggc actatggcat
      361 tacctctcct atcagcttag cagcccccaa ggagaccgac tgcctactca cacagaaact
      421 catcgagacg ctgaagccct ttggggtttt tgaagaagaa gaggaactgc agcgcaggat
      481 tttaattttg ggaaaattaa ataacctggt gaaagaatgg atacgagaaa tcagtgaaag
      541 caagaatctt ccacaatctg taattgaaaa tgttggagga aaaattttta catttggatc
      601 ctacagacta ggagtacata cgaaaggtgc tgatattgat gcgttgtgtg ttgcaccaag
      661 acatgttgat cgaagtgatt ttttcacctc attctatgat aaattgaaat tacaagaaga
      721 agtgaaagat ttaagagctg ttgaagaggc atttgtacca gttatcaaac tctgttttga
      781 tggaatagag attgatattt tgtttgcaag attagcactg cagactattc cagaagattt
      841 ggacctacga gatgacagtc tgcttaaaaa cctagatata agatgcataa gaagccttaa
      901 tggttgcagg gtaaccgatg agattttaca tctagtacca aacattgaca acttcaggtt
      961 aactctgaga gccatcaaac tgtgggccaa acggcacaac atctattcca atatattagg
     1021 tttcctcggt ggtgtttcct gggctatgct agtagcaaga acttgccagc tttatccaaa
     1081 tgcaatagca tcaactcttg tacataaatt tttcttggta ttttctaaat gggaatggcc
     1141 aaatccagtg ctattgaaac agcctgaaga atgcaatctt aatttgcctg tgtgggaccc
     1201 aagggtaaac cccagtgata ggtaccatct tatgcctata attacaccag catacccaca
     1261 acagaactcc acgtacaatg tgtccgtttc aacacggatg gtcatggttg aggagtttaa
     1321 acaaggtctt gctatcacag atgaaatttt gctgagtaag gcagagtggt ccaaactttt
     1381 tgaagctcca aacttctttc aaaagtacaa gcattatatt gtacttctag caagtgcgcc
     1441 cacggaaaag cagcgtctgg aatgggtggg cttggtggaa tcaaaaattc gtatcctggt
     1501 tggaagttta gagaagaatg agtttattac actggctcat gtgaatcccc agtcatttcc
     1561 agcccccaag gaaagtcctg atagggaaga atttcgcaca atgtgggtga ttggtttagt
     1621 gtttaaaaaa actgaaaact ctgagaatct cagtgtggac ctcacctatg atatccagtc
     1681 tttcacagac acagtttata ggcaagcaat aaacagcaag atgtttgagt tggatatgaa
     1741 gatcgcagca atgcatgtga agagaaagca gctccaccag ctgctgccaa gtcatgtgct
     1801 tcagaagagg aagaagcatt caacagaagg agtcaagtta gcagctctga atgacagcag
     1861 ccttgacttg tctatggaca gtgataacag catgtctgtg ccttcaccca ccagtgctat
     1921 gaagaccagt ccattgaaca gttctggcag ctctcagggc agaaacagtc ctgctccagc
     1981 tgtgaccgca gcatctgtga ccagcattca ggcttctgag gtttctgtac cacaagcaaa
     2041 ttccagtgaa agcccagggg gtccatcgag cgaaagcatt cctcaaactg ccacacagcc
     2101 agccatttct ccaccaccaa agcctacagt ctccagagtt gtctcctcaa cacgactggt
     2161 aaacccgtcg cctagacctt caggaaacgc agcaacaaaa gtacctaatc ctatagtagg
     2221 agtcaagaga acgtcctcac cccataaaga agaaagtcct aagaaaacca aaacagaaga
     2281 ggatgaaaca agtgaagatg ctaactgtct tgctttgagt ggacatgata aaacagagac
     2341 aaaggaacaa gttggcatgg agacaagtgc ggctccgtca gaagctgctc cggcctcggc
     2401 gtctctggtg gcctctcagg aggaagcagt gggagacgca tcccctgtga gcgacagtgc
     2461 tttaaaccgt gctgtgttct ttgctttcgt tctcagaaaa catccagtac agacctttcc
     2521 gatatccctg ctctccctgc aaaccctatt cctgttatca agaattcaat aaaactgaga
     2581 ctgaatcggt aaaaccacct cagggtccat aaacagtatc tgccaactca acccgttgtc
     2641 tccagatgct taaacaaaag aaagaaagaa aaaagaaagg agaaaggaga ttggagggac
     2701 aggactagcc ctgactgact gggtttagtc ttggtgacct cccttacttg ggctcatcag
     2761 cacttgatca gcagtccagg ttagtatgga agccaggagt actgttatta ttgtgttagc
     2821 aacagttgca ttaactattt cagaaaaatt actgccttta agaaggaaag aaaacaaaac
     2881 cctcaagctg cgtttgtatc cataattgac atccagattg ggtttatgtg tgatgatgca
     2941 ttgtttggaa aattgcaata caaactggca taagaactcc ttattctgat gatgcacttt
     3001 tatgtatttt ttttattaga aagtagaact aattttagat tttcagctta atggattttc
     3061 aatttttttc ccaaagaatt ttctttacaa ttagtcttta aattggattc cttgtgcagt
     3121 ggtgtaccat tctgcctcag aaaggacagt aggacaccta gctcagtcct tacgggcagc
     3181 tgtaaccctt agggtgcatt gtcaatgcta aggtatactt tggacactga aagaagaatt
     3241 aggcgatact tggttttgat gaggttatga ttaagaagta tatattcctt ttatttatag
     3301 agttgtttta tagtgcatac aaatcagcag tcagccaaca agtgtggtct ttgagctttc
     3361 tcaagctctg ttcttttgcc ttcagtctgt tagtctttga aacaacgaca gtgctttctc
     3421 cccatccccc ttttttcttt tgcctgtttt tcccttttgc ttgaatgcac aaggtaaggc
     3481 ttatttcaca gaaaccagaa tgccagtatt ttcctaagcc atgacatgta accgtgacct
     3541 gtggctacgt gacacagaac actaacgttg gtcccatggc tagaacttga gaatgactga
     3601 aagccatacc cgtgaagcat ctccggagga tggccatttg atctctgaga ggacttttgt
     3661 acactccaca gaactcctgt tcctgtctta cacaaagttg attttcaatt ttaaaagtgg
     3721 gcaaaaaggc attttcttcc agatttttaa actaattttt atttttaacc agtttatcaa
     3781 aatttgtcag tgaattttac atacagaaac attttaaaaa tcattcctag taagcacttg
     3841 acgtttagtc agctctccac ttttgaattt ttttgttcta tcaaaaatta gaaacttcct
     3901 ttaaagacaa tgatttctca taattaagta gcagaattct cgtccatctt gtgacgtgtg
     3961 aggacgccag aggttgataa ggttcctctt gtcgatctgg gtagagcagg cctgtagcag
     4021 cagatctttg tatgagcatg gtttccaatc cttcatctcg ctgcattcta tcacacattt
     4081 gtgcattttc acgtaacact gcaattaaac tctcctgtcc tcctaaatta atttccaaag
     4141 ttggagtata gtctttccct tcagctgtgc attaattaag gctttcttta ccacttacat
     4201 tgtttatata cagtgttctt tctgctctcc acctctcgct ctgcagtcac cttgccctcc
     4261 ctccctccct gcctccctcc ctcccaccac ttgagtaaag aagacagttc gctaacaggt
     4321 gacatgtccc gtgtctgtgt gtgtagctgc agagttagat tgacatcacc aggcacagat
     4381 ttagtcttgt cgttttgttt acacattggg gaaaaattca gtttaataaa cgttccatgt
     4441 aactgcatcc aagtttcacc aggctggaga cgtggatctt ttctgtgtag tgacttttta
     4501 cttctagttt ccataacctg gagatcagac tgttgctttc gcatgatgta agtagtgtct
     4561 catgactgga gtttgctttg ttttatagta tctgtactcc ttgtattttt caagagctat
     4621 tttgtaaaca gatgatgtat ttctccattg aaaacacaat aaaaaaaaaa aaggcacaaa
     4681 tccca
//
