LOCUS       NM_001305995            2510 bp    mRNA    linear   ROD 29-MAR-2024
DEFINITION  Rattus norvegicus paralemmin A kinase anchor protein (Pakap),
            transcript variant 3, mRNA.
ACCESSION   NM_001305995
VERSION     NM_001305995.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2510)
  AUTHORS   Carnegie,G.K., Means,C.K. and Scott,J.D.
  TITLE     A-kinase anchoring proteins: from protein complexes to physiology
            and disease
  JOURNAL   IUBMB Life 61 (4), 394-406 (2009)
   PUBMED   19319965
  REMARK    Review article
REFERENCE   2  (bases 1 to 2510)
  AUTHORS   Kinderman,F.S., Kim,C., von Daake,S., Ma,Y., Pham,B.Q.,
            Spraggon,G., Xuong,N.H., Jennings,P.A. and Taylor,S.S.
  TITLE     A dynamic mechanism for AKAP binding to RII isoforms of
            cAMP-dependent protein kinase
  JOURNAL   Mol Cell 24 (3), 397-408 (2006)
   PUBMED   17081990
REFERENCE   3  (bases 1 to 2510)
  AUTHORS   Tasken,K. and Aandahl,E.M.
  TITLE     Localized effects of cAMP mediated by distinct routes of protein
            kinase A
  JOURNAL   Physiol Rev 84 (1), 137-167 (2004)
   PUBMED   14715913
  REMARK    Review article
REFERENCE   4  (bases 1 to 2510)
  AUTHORS   Dong,F., Feldmesser,M., Casadevall,A. and Rubin,C.S.
  TITLE     Molecular characterization of a cDNA that encodes six isoforms of a
            novel murine A kinase anchor protein
  JOURNAL   J Biol Chem 273 (11), 6533-6541 (1998)
   PUBMED   9497389
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000005.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643286.16603.1,
                                           SRR26360194.819909.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760386, SAMEA5760389
                                           [ECO:0000348]
            ##Evidence-Data-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-252               JAXUCZ010000005.1  77108793-77109044
            253-333             JAXUCZ010000005.1  77176065-77176145
            334-464             JAXUCZ010000005.1  77186199-77186329
            465-579             JAXUCZ010000005.1  77224648-77224762
            580-601             JAXUCZ010000005.1  77225760-77225781
            602-2510            JAXUCZ010000005.1  77243878-77245786
FEATURES             Location/Qualifiers
     source          1..2510
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="5"
                     /map="5q24"
     gene            1..2510
                     /gene="Pakap"
                     /gene_synonym="AKAP-2; Akap2; Palm2"
                     /note="paralemmin A kinase anchor protein"
                     /db_xref="GeneID:298024"
                     /db_xref="RGD:1305135"
     exon            1..252
                     /gene="Pakap"
                     /gene_synonym="AKAP-2; Akap2; Palm2"
                     /inference="alignment:Splign:2.1.0"
     CDS             208..1338
                     /gene="Pakap"
                     /gene_synonym="AKAP-2; Akap2; Palm2"
                     /note="isoform 3 is encoded by transcript variant 3;
                     A-kinase anchor protein 2; A kinase (PRKA) anchor protein
                     2; paralemmin 2; paralemmin-2-like; A-kinase anchoring
                     protein 2"
                     /codon_start=1
                     /product="A-kinase anchor protein 2 isoform 3"
                     /protein_id="NP_001292924.1"
                     /db_xref="GeneID:298024"
                     /db_xref="RGD:1305135"
                     /translation="MAEAELHKERLQAIAEKRKRQTEIEGKRQQLDEQVLLLQHSKSK
                     VLREKWLLQGVPAGTAEEEEARRRQSEEDEFKVKQLEDNIQRLEQEIQALESEESQIS
                     AKEQIILEKLKETEKSFKDLQKSFSTADGAIYAMEINVEKDKQTGETKILSASTIGPE
                     GVHQRGVKVYDDGTKVVYEVHSGGTVVENGVHKLSAKDVEELIQKAGQSSFRGHMSER
                     TVVADGSLGHPKEHMLCKEAKLEMVQKSRKDQSSGNPGHQAQPPSTEGPEVNLDQPVT
                     MIFMGYQNIEDEEETKKVLGYDETIKAELVLIDEDDEKSLREKTVTDVSTIDGNAAEL
                     VSGRPMSDTTEPSSPEDKEESLATDPAPGTQKKKRCQCCVVM"
     exon            253..333
                     /gene="Pakap"
                     /gene_synonym="AKAP-2; Akap2; Palm2"
                     /inference="alignment:Splign:2.1.0"
     exon            334..464
                     /gene="Pakap"
                     /gene_synonym="AKAP-2; Akap2; Palm2"
                     /inference="alignment:Splign:2.1.0"
     exon            465..579
                     /gene="Pakap"
                     /gene_synonym="AKAP-2; Akap2; Palm2"
                     /inference="alignment:Splign:2.1.0"
     exon            580..601
                     /gene="Pakap"
                     /gene_synonym="AKAP-2; Akap2; Palm2"
                     /inference="alignment:Splign:2.1.0"
     exon            602..2510
                     /gene="Pakap"
                     /gene_synonym="AKAP-2; Akap2; Palm2"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cggccgcgcc ggtggagacc gaggctgagc tctgagccag ccgtgcgcac agctttaccc
       61 gccccccagg agcagacccc acgcgccctt aggctgtccc cgggatccag ttgagtcccc
      121 cacgggtgcc ctttcatcat cttgggtgac tacagcgtgt gttttgtttt tcttccttct
      181 tcccctgccc gtgtgccctt ctccaggatg gcagaggcgg aattgcacaa ggagaggctg
      241 caagccatag cagaaaaaag aaagaggcag acggaaatag aagggaagag acaacagctt
      301 gacgagcagg tgctgctgct ccaacattcc aagtccaaag tgcttcggga aaaatggctg
      361 ctgcagggtg taccggcggg aacagcggag gaggaggaag ccagacgccg acagtctgag
      421 gaggatgaat tcaaagtcaa gcagcttgaa gataacattc agaggctgga gcaggaaata
      481 caagcgctcg aaagcgaaga gtcccagata tcggccaaag agcagatcat cctcgagaaa
      541 ctgaaggaga cagagaaatc cttcaaggac ttgcagaaga gtttctccac tgctgatgga
      601 gctatatacg ccatggaaat taatgtggag aaagacaaac aaacaggaga gaccaagatt
      661 ctctctgcat ccaccattgg cccagagggg gtccatcaga gaggagtcaa agtctatgat
      721 gatggtacca aagtagtgta tgaggtgcac tcaggaggca ccgtggtaga gaacggagtc
      781 cacaaactaa gcgcaaagga tgtggaagag ctaattcaga aggctggaca atcgagcttc
      841 agaggacaca tgtcagaaag aactgttgtt gcagatggga gcctaggcca tcccaaggaa
      901 cacatgctct gcaaagaggc caagttagaa atggtgcaaa aatccaggaa agatcagtct
      961 tcgggaaacc ccgggcacca agcccaaccc cccagcacag agggtccaga ggtcaacctg
     1021 gatcaaccgg tcaccatgat ttttatgggc taccaaaaca tcgaggatga agaggagact
     1081 aagaaggtgc taggctatga cgaaaccatc aaggccgaat tagtgctgat tgacgaagac
     1141 gatgaaaagt cgctgaggga gaagacagtg acggatgtgt ccacgatcga tgggaatgca
     1201 gctgaactgg tgtccggcag gcccatgtcg gacaccacag aaccctcatc cccagaagac
     1261 aaggaagaga gcctggccac agacccggcc ccaggtaccc aaaagaaaaa gcgctgtcaa
     1321 tgctgtgttg tcatgtgacc acttctttct cctccccttt cttccgggca gcctctctac
     1381 tctccgcctc ttaaatagac ctcactgtac cactaactgc gatactgtga actggaagca
     1441 atcacctgcc ttgcctcgca gttggatttg ctttgatctc tccctcacat ctttcctcct
     1501 cctcacttgg gaaacaacgt gcatgtgtgt gcttcatttt ctccccccaa gaacttacat
     1561 tttttccctc taaacctttc tttgtgtctt cgagagttga atccgtgcgc tactactcaa
     1621 ttggagtgga ctcttcatag cagctggtta tcttgtagcc ttaattgact tgactggact
     1681 ccaaccgttg gcaccggggg ttttcatttc ggcgtgtgtt cctctaacct agacctagac
     1741 acacacacac acacacacac acacacacac acacacacac acacacactg ccgtgcccct
     1801 ggcttctcac ctgcctcctc tgctgtgtag atctttgttt ttatatcttg tgtggcagaa
     1861 atgctgtggg ctgtagccgg ttgctagcgt agccaaaagt ggacctacct taatctgggc
     1921 tgttctagga tgacgctttt cctttgctgc cttacgtaag cttccagatt ccagtattgt
     1981 gctttccttc tgttaaaacc acaatgaagt tgacctgaga gcaaagaacc cagcgcctgt
     2041 cccagcggaa gtgtagggac tgactcccca cctggcggtc agcagctctc tatggcttac
     2101 gcaatgaacc ctttgtacgg gattttctaa ggacctcagg ccaccattgt tctctgcgcc
     2161 cgctgtgctc gccagtccac aagccttgtt tccatgctcc cccaaaatgt aaagtttcat
     2221 attgttttcc ttttcatgta tattttctga tagaactcat ctattttcaa agaggggatc
     2281 gttttgagag gtctctctac agtgaccata ttccttaaaa cagtctttct gacatagtgg
     2341 ggctgtcata atatccccca ctgtatcaag gatggtgctg tatgcattaa ctgtccattt
     2401 cctgcgccca gtcttacatc tgtgcttttt taaaatttaa tgttcccatg ggttagagaa
     2461 tgtttcaggt aacgtcaata tataagtatc ttcactcaaa aaaaaaaaaa
//
