LOCUS       NM_130829               2671 bp    mRNA    linear   ROD 01-APR-2024
DEFINITION  Rattus norvegicus paralemmin (Palm), mRNA.
ACCESSION   NM_130829
VERSION     NM_130829.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2671)
  AUTHORS   Arstikaitis,P., Gauthier-Campbell,C., Carolina Gutierrez
            Herrera,R., Huang,K., Levinson,J.N., Murphy,T.H., Kilimann,M.W.,
            Sala,C., Colicos,M.A. and El-Husseini,A.
  TITLE     Paralemmin-1, a modulator of filopodia induction is required for
            spine maturation
  JOURNAL   Mol Biol Cell 19 (5), 2026-2038 (2008)
   PUBMED   18287537
  REMARK    GeneRIF: This study identifies a key role for paralemmin-1 in spine
            maturation through modulation of filopodia induction.
REFERENCE   2  (bases 1 to 2671)
  AUTHORS   Munton,R.P., Tweedie-Cullen,R., Livingstone-Zatchej,M.,
            Weinandy,F., Waidelich,M., Longo,D., Gehrig,P., Potthast,F.,
            Rutishauser,D., Gerrits,B., Panse,C., Schlapbach,R. and Mansuy,I.M.
  TITLE     Qualitative and quantitative analyses of protein phosphorylation in
            naive and stimulated mouse synaptosomal preparations
  JOURNAL   Mol Cell Proteomics 6 (2), 283-293 (2007)
   PUBMED   17114649
REFERENCE   3  (bases 1 to 2671)
  AUTHORS   Kutzleb,C., Petrasch-Parwez,E. and Kilimann,M.W.
  TITLE     Cellular and subcellular localization of paralemmin-1, a protein
            involved in cell shape control, in the rat brain, adrenal gland and
            kidney
  JOURNAL   Histochem Cell Biol 127 (1), 13-30 (2007)
   PUBMED   16847661
  REMARK    GeneRIF: analysis of the cellular and subcellular localization of
            paralemmin-1 in the rat tissues is consistent with a role for
            paralemmin-1 in the formation and stabilization of plasma membrane
            elaborations, in neurons as well as in other cell types
REFERENCE   4  (bases 1 to 2671)
  AUTHORS   Basile,M., Lin,R., Kabbani,N., Karpa,K., Kilimann,M., Simpson,I.
            and Kester,M.
  TITLE     Paralemmin interacts with D3 dopamine receptors: implications for
            membrane localization and cAMP signaling
  JOURNAL   Arch Biochem Biophys 446 (1), 60-68 (2006)
   PUBMED   16386234
REFERENCE   5  (bases 1 to 2671)
  AUTHORS   Gauthier-Campbell,C., Bredt,D.S., Murphy,T.H. and
            El-Husseini,Ael.-D.
  TITLE     Regulation of dendritic branching and filopodia formation in
            hippocampal neurons by specific acylated protein motifs
  JOURNAL   Mol Biol Cell 15 (5), 2205-2217 (2004)
   PUBMED   14978216
REFERENCE   6  (bases 1 to 2671)
  AUTHORS   Hu,B., Copeland,N.G., Gilbert,D.J., Jenkins,N.A. and Kilimann,M.W.
  TITLE     The paralemmin protein family: identification of paralemmin-2, an
            isoform differentially spliced to AKAP2/AKAP-KL, and of
            palmdelphin, a more distant cytosolic relative
  JOURNAL   Biochem Biophys Res Commun 285 (5), 1369-1376 (2001)
   PUBMED   11478809
REFERENCE   7  (bases 1 to 2671)
  AUTHORS   Kutzleb,C., Sanders,G., Yamamoto,R., Wang,X., Lichte,B.,
            Petrasch-Parwez,E. and Kilimann,M.W.
  TITLE     Paralemmin, a prenyl-palmitoyl-anchored phosphoprotein abundant in
            neurons and implicated in plasma membrane dynamics and cell process
            formation
  JOURNAL   J Cell Biol 143 (3), 795-813 (1998)
   PUBMED   9813098
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000007.1 and BC072525.1.
            
            On Apr 7, 2017 this sequence version replaced NM_130829.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC072525.1, AB058889.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760393,
                                           SAMEA5760433 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-36                JAXUCZ010000007.1  10562972-10563007   c
            37-2671             BC072525.1         1-2635
FEATURES             Location/Qualifiers
     source          1..2671
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="7"
                     /map="7q11"
     gene            1..2671
                     /gene="Palm"
                     /note="paralemmin"
                     /db_xref="GeneID:170673"
                     /db_xref="RGD:620341"
     exon            1..137
                     /gene="Palm"
                     /inference="alignment:Splign:2.1.0"
     CDS             133..1284
                     /gene="Palm"
                     /codon_start=1
                     /product="paralemmin-1"
                     /protein_id="NP_570842.1"
                     /db_xref="GeneID:170673"
                     /db_xref="RGD:620341"
                     /translation="MEVLATDTVSQQERLQAIAEKRRKQAEIESKRRQLEDDRRQLQY
                     LKSKALRERWLLEGTPSSASEGDEDMRKQMQEDEQKARSLEESITRLEKEIDVLEFGE
                     SAPAAPKENSAAPSPIRPHSTSPAKEEQKSETMVNAQQTPLGTPKENRKSTPVRSPGG
                     STMMKAAMYSVEITVEKDKVTGETRVLSSTTLLPRDPLPQGVKVYEDETKVVHAVDGL
                     SENGIQPLSSSEVDELIHKADEVTLSEAGSTTGPAEPRGLAEDVTRTTPSRREITGVE
                     AQPGEATSGPPGIQPGQEPPVTMVFMGYQNVEDEAETKKVLGLQDTIKAELVVIEDSV
                     TPREPAPLNGSAAELPATKEENQTGPTTTPSDTQDLDMKKPRCRCCSVM"
     exon            138..189
                     /gene="Palm"
                     /inference="alignment:Splign:2.1.0"
     exon            190..270
                     /gene="Palm"
                     /inference="alignment:Splign:2.1.0"
     exon            271..401
                     /gene="Palm"
                     /inference="alignment:Splign:2.1.0"
     exon            402..552
                     /gene="Palm"
                     /inference="alignment:Splign:2.1.0"
     exon            553..574
                     /gene="Palm"
                     /inference="alignment:Splign:2.1.0"
     exon            575..631
                     /gene="Palm"
                     /inference="alignment:Splign:2.1.0"
     exon            632..763
                     /gene="Palm"
                     /inference="alignment:Splign:2.1.0"
     exon            764..2650
                     /gene="Palm"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cgcgcccgga caatacccgg cgcgctgggg acgatgcccg ccccggtgcc gcccccgcgc
       61 cgcacaaccc cggccgccag gccctagagt cggccctgcc ccgtgctgca ccgcccacgg
      121 acctcgcggg agatggaggt cctggcgaca gacactgtgt cccagcagga gcggcttcaa
      181 gcaatcgctg agaagcgtag gaagcaggca gagattgaga gcaagcggag acaattggag
      241 gatgaccgaa gacagctgca gtacctgaag tccaaggcac ttcgggaacg ctggctgctg
      301 gaggggacac catcctcagc ctcggagggc gacgaggaca tgaggaagca gatgcaggag
      361 gatgaacaga aagcccggag cctggaggag tccatcacca gactcgagaa agaaattgat
      421 gtcctagagt tcggtgagtc agccccagct gccccaaagg agaactcagc ggcccccagc
      481 cccatccggc cccactctac aagccccgcc aaggaggagc aaaagtcaga aaccatggtg
      541 aacgcccagc agactccact gggcacccca aaagagaatc gaaagtccac accggtgcgg
      601 agtcccgggg gatccacgat gatgaaggca gccatgtatt cggtggagat cacggtggag
      661 aaggacaagg tgaccgggga gaccagggtg ctgtccagca ccacattgct cccccgggac
      721 ccactccctc agggcgtgaa agtctacgag gacgaaacaa aagtggtcca tgccgtggac
      781 ggcctctctg agaacggaat ccagcctcta agttcctccg aggtggatga actcattcac
      841 aaggccgatg aggtcacact gagtgaggcc gggtccacaa ctgggccagc agagcctcgg
      901 ggactcgcag aggatgtcac caggaccaca ccatccagaa gggagatcac aggagtcgag
      961 gctcagccag gagaggccac gtcaggcccg ccaggcatcc agcccggtca ggagcccccg
     1021 gtcaccatgg tcttcatggg ttatcagaat gtggaagatg aagcagagac caagaaggta
     1081 ctcggcctgc aggacaccat caaggctgaa ctggtggtga ttgaagactc ggtcaccccc
     1141 agggagcctg caccactcaa tggcagcgcg gctgagctcc cagccaccaa ggaggagaac
     1201 cagacggggc ccacgaccac acccagcgac acccaagatc ttgacatgaa gaagcctcgc
     1261 tgtagatgct gttctgtcat gtgagccgtc ggggcacccc agtccccggt ccctgtccta
     1321 tgctccacac tcaaacccag cagcccggcc ctccccggcg cctgcccacc ttcaccctcc
     1381 gcctcacagg ccccagacac gtgtgtggtc cctatgcacc tcgagtcgcg ggtggggggt
     1441 gctgtgcccg tcaccacact ccacactcac cccgtacctc tgagccgtgt gtcatccctt
     1501 ggtgagagac aggctgaccc ttatcagccc ctctaagaat ggggatcccc ccagtccagg
     1561 tcacagcagg tttacacagg tggcttatgc ccaccatggt cccagcctgg tgtccccttg
     1621 ccgccccagg ccagcctgtc tgtgccttat tgttactttt ggggagtctc cgaggggacc
     1681 agaaaggctc tccctggcca aggcgccagc agccaaatgt gggcaagtga gatgaggcca
     1741 cacttctttg gggactcaaa gtcttgacgt cctaacgtgg aggacgggca cctgtggatc
     1801 ccctccagta ggtagcggag ctcaaaacag gagaagccct tcactgggga tggaacagtc
     1861 acccacaaga tggagtcatt gttggtcagc caagccactc cctgtcctaa gtgtcccctc
     1921 ccctccatgc acacactggg cccttcttcc tggtgctaat tttgggacct tcggggtcac
     1981 ctctgccctc ttctctagtt ggcttggacc agggtcctgg gtttcccaca tacccccata
     2041 ccccagaagt cagtgggtat gtctgccagc actgcaaagc ctagcgtttc caggcaggat
     2101 taggttgctc cacacacaca ccttgggtgg gagtaaggga accccccacc tgccacctgg
     2161 ccagacggga gcctggcagg aggtcaccaa ccttcgggca gacaggcagc agtagccact
     2221 ttggtcccca gaggcacaac cttgcacaca ggcgctgact cagcttcaaa ggaccacgcc
     2281 cggtccaggt ccctttcttg ggactccagc ctggtgtgca gcagggcaca ggaccccctg
     2341 cagagtcccg tcactacccg cagctgcagt agggccacaa gcagaggcca cgacggggtc
     2401 tgtgtcccgt ccttcccgtg gcctggagga gaggcgctct tcactgaggg gtgacccatg
     2461 gccacggtca tggtgcccct ccttttcctc ctcctctgat tctgcctgag ttcctcaagc
     2521 cctgagcctc ggctgaagtg cccttgctgc ccccttctgc ttttgacgtg tgacgaggcc
     2581 ccacccttca cccccatgtt cttgactttc ccagagaaac agattaaaaa aaaaaaaaaa
     2641 agtgtgcaga aaaaaaaaaa aaaaaaaaaa a
//
